ライフサイエンスコーパス: pathogenicity island

1 uding those carrying virulence determinants (pathogenicity islands).

2 se II (MPII)) are encoded by the B. fragilis pathogenicity island.

3 glJ, or pdpC, three genes of the Francisella pathogenicity island.

4 nd dependent upon a functional H. pylori cag pathogenicity island.

5 binding protein HilD encoded in a different pathogenicity island.

6 Type III secretion system encoded in the LEE pathogenicity island.

7 ion of an H. pylori host receptor by the cag pathogenicity island.

8 (AIEC) that harbors the yersiniabactin (Ybt) pathogenicity island.

9 y using the genes encoded in the Francisella pathogenicity island.

10 tivation of the tcpPH promoter on the Vibrio pathogenicity island.

11 iosynthetic assembly line encoded by the pks pathogenicity island.

12 cteria carrying the colibactin-producing pks pathogenicity island.

13 suppression of the virulence-associated LEE pathogenicity island.

14 borne on the locus of enterocyte effacement pathogenicity island.

15 ial virulence loci encoded within Salmonella pathogenicity islands.

16 open reading frames with characteristics of pathogenicity islands.

17 sing AraC-type transcriptional regulators in pathogenicity islands.

18 neated by CGH in addition to the three known pathogenicity islands.

19 tal acquisition of diverse papGII-containing pathogenicity islands.

20 nce plasmid and, in some cases, the Shigella pathogenicity islands.

21 Staphylococcus aureus pathogenicity island 1 (SaPI1) is a mobile genetic eleme

22 r genes--hilA, invF, and ssrA--in Salmonella pathogenicity island 1 (SPI-1) and 2 (SPI-2), by binding

23 and SC2, harboring variations in Salmonella pathogenicity island 1 (SPI-1) and SPI-2 and exhibiting

24 nterica serovar Typhimurium (S. Typhimurium) pathogenicity island 1 (SPI-1) encodes a type III secret

25 In Salmonella, the Salmonella pathogenicity island 1 (SPI-1) encodes a type three secr

26 aspase-1 activation and, in part, Salmonella pathogenicity island 1 (SPI-1) expression by Salmonella.

27 enhanced bacterial expression of Salmonella pathogenicity island 1 (SPI-1) genes and increased intra

28 cription of the flagellar and the Salmonella pathogenicity island 1 (SPI-1) regulons in a FliZ-depend

29 biquitination is triggered by the Salmonella pathogenicity island 1 (SPI-1) T3SS effectors SopB and S

30 ype III secretion systems (T3SSs)-Salmonella pathogenicity island 1 (SPI-1) T3SS, SPI-2 T3SS, and the

31 pecialized organelle known as the Salmonella pathogenicity island 1 (SPI-1) type 3 secretion system (

32 onal switch is independent of the Salmonella pathogenicity island 1 (SPI-1) type III secretion system

33 ella enterica serovar Typhimurium Salmonella pathogenicity island 1 (SPI-1) type III secretion system

34 e numerous virulence genes within Salmonella pathogenicity island 1 (SPI-1), newly identified flagell

35 terica subsp. salamae encodes the Salmonella pathogenicity island 1 (SPI-1), SPI-2, and the locus of

36 H and mutS genes at the 3' end of Salmonella Pathogenicity Island 1 (SPI-1), ste fimbrial operon, and

37 codes the master-regulator of the Salmonella Pathogenicity Island 1 (SPI-1), was present in the adapt

38 Here, starting with the 35 kb Salmonella pathogenicity island 1 (SPI-1), we eliminated internal r

39 ecretion system (T3SS) encoded in Salmonella pathogenicity island 1 (SPI-1), while macrophage surviva

40 absence and presence of bile in a Salmonella pathogenicity island 1 (SPI-1)-dependent manner.

41 body interferes specifically with Salmonella pathogenicity island 1 (SPI-1)-dependent, but not SPI-1-

42 the Salmonella enterica serovar Typhimurium pathogenicity island 1 (SPI-1)-encoded TTSS are required

43 Host interactions are mediated by Salmonella pathogenicity island 1 (SPI-1).

44 ion system 1 (TTSS-1), encoded on Salmonella pathogenicity island 1 (SPI-1).

45 I secretion system encoded within Salmonella pathogenicity island 1 (SPI-1).

46 ependent on multiple genes within Salmonella pathogenicity island 1 (SPI-1).

47 s, many of which are found within Salmonella pathogenicity island 1 (SPI-1).

48 Salmonella pathogenicity island 1 (SPI1) and SPI4 have previously b

49 Infection with a Salmonella pathogenicity island 1 (SPI1) mutant did not result in m

50 ransferase Pat regulates genes on Salmonella Pathogenicity Island 1 (SPI1) that are required for the

51 ecretion system (TTSS) encoded by Salmonella pathogenicity island 1 (SPI1) that were previously shown

52 yphimurium uses a T3SS encoded by Salmonella pathogenicity island 1 (SPI1) to actively invade cells t

53 rica serovar Typhimurium uses the Salmonella pathogenicity island 1 (SPI1) type III secretion system

54 stinal epithelial cells using the Salmonella pathogenicity island 1 (SPI1) type III secretion system

55 o the host cell cytoplasm via the Salmonella pathogenicity island 1 (SPI1) type III secretion system

56 aperone sigma(28), the removal of Salmonella pathogenicity island 1 (Spi1), the removal of flagellar

57 um employing genes encoded within Salmonella Pathogenicity Island 1 (SPI1).

58 tion system (T3SS) encoded within Salmonella pathogenicity island 1 (SPI1).

59 S); the T3SS genes are carried on Salmonella pathogenicity island 1 (SPI1).

60 effect of fim gene expression on Salmonella pathogenicity island 1 (SPI1).

61 e III secretion system encoded on Salmonella pathogenicity island 1 (SPI1).

62 ecretion system (T3SS) encoded on Salmonella pathogenicity island 1 (SPI1).

63 volved in cholera disease is the V. cholerae pathogenicity island 1 (VPI-1).

64 ibute to enteric infection (e.g., Salmonella pathogenicity island 1 [SPI-1], SPI-4, SPI-5, CS54, fliH

65 i cell entry was dependent on the Salmonella pathogenicity island 1 and Shigella mxi/spa type III sec

66 ical Salmonella enterica serovar Typhimurium pathogenicity island 1 basal body, determined using sing

67 A network encoded within Salmonella Pathogenicity Island 1 controls the expression of a type

68 nuclear leukocytes, SipA or other Salmonella pathogenicity island 1 effectors had no effect on induct

69 both a repressor and activator of Salmonella Pathogenicity Island 1 gene expression, and both regulat

70 rium invA mutant defective in the Salmonella pathogenicity island 1 invasion apparatus was less capab

71 onella enterica invasion genes on Salmonella pathogenicity island 1 is under the control of the compl

72 t observed after infection with a Salmonella pathogenicity island 1 mutant deficient in type III secr

73 hanges within the genomic area of Salmonella pathogenicity island 1 suggesting that these genes are i

74 gellin translocation required the Salmonella Pathogenicity Island 1 Type III secretion system (SPI-1

75 A functional Salmonella pathogenicity island 1 type III secretion system appears

76 roteins secreted by the bacterial Salmonella pathogenicity island 1- and Salmonella pathogenicity isl

77 cretion systems (TTSS) encoded in Salmonella pathogenicity islands 1 and 2 (SPI-1 and SPI-2) that del

78 sion of representative genes from Salmonella pathogenicity islands 1 and 2 (SPI1 and SPI2) and the im

79 nds on the virulence determinants Salmonella pathogenicity islands 1 and 2, and it is characterized b

80 virulence determinants, including Salmonella Pathogenicity Islands 1, 2, 3, 4, and 6.

81 s (T3SSs) encoded in two distinct Salmonella pathogenicity islands, 1 and 2 (SPI1 and SPI2, respectiv

82 tellaria baicalensis, targets S. Typhimurium pathogenicity island-1 (SPI-1) type III secretion system

83 S. typhimurium has two T3SS: Salmonella pathogenicity island-1 (SPI1), which encodes the rod pro

84 We investigated the roles of Salmonella pathogenicity island 2 (SPI-2) and two SPI-2 effectors i

85 ls, bacteria failed to upregulate Salmonella pathogenicity island 2 (SPI-2) genes and did not form a

86 While the T3SS within Salmonella pathogenicity island 2 (SPI-2) has been previously shown

87 Our results demonstrated that the Salmonella pathogenicity island 2 (SPI-2) T3SS assembled into a fun

88 effect was dependent on an intact Salmonella pathogenicity island 2 (SPI-2) type 3 secretion system.

89 acuolar membrane pore made by the Salmonella pathogenicity island 2 (SPI-2) type III secretion system

90 ke putative C-ring protein of the Salmonella pathogenicity island 2 (SPI-2)-encoded T3SS.

91 acidifies to pH 5.6; acidification activates pathogenicity island 2 (SPI-2).

92 B two-component system located on Salmonella pathogenicity island 2 (SPI-2).

93 virulence factors encoded by the Salmonella pathogenicity island 2 (SPI-2).

94 endent regulation of genes within Salmonella pathogenicity island 2 (SPI-2).

95 Because PhoP-regulated Salmonella pathogenicity island 2 (SPI2) genes are also repressed b

96 rison of candidate genes from the Salmonella Pathogenicity Island 2 (SPI2) locus was conducted in the

97 iesis in a process independent of Salmonella pathogenicity island 2 (SPI2) or flagellin.

98 We show herein that the Salmonella pathogenicity island 2 (SPI2) response regulator SsrB un

99 translocator and effector of the Salmonella pathogenicity island 2 (SPI2) type III secretion system,

100 (TLR)-dependent signals to induce Salmonella Pathogenicity Island 2 (SPI2), a locus required for intr

101 Vibrio pathogenicity island 2 (VPI-2), a 57-kb region found exc

102 sin (HlyA); C-II encodes a variant of Vibrio pathogenicity island 2 (VPI-2), and Vibrio seventh pande

103 lso preserve the transcription of Salmonella pathogenicity island 2 gene targets from the inhibitory

104 trate up-regulation of particular Salmonella pathogenicity island 2 genes (especially spiC) and incre

105 Salmonella virulence depends in part on its pathogenicity island 2 type III secretion system (SPI-2

106 ofessional phagocytes through the Salmonella pathogenicity island 2 type III secretion system (TTSS).

107 murium virulence determinant, the Salmonella pathogenicity island 2 type III secretion system, is req

108 The Salmonella Pathogenicity Island-2 (i.e. SPI-2) encodes a unique typ

109 Vibrio pathogenicity island-2 (VPI-2) is a 57-kb region integra

110 cteria in a process that required Salmonella pathogenicity island-2 and correlated with increased exp

111 nella pathogenicity island 1- and Salmonella pathogenicity island-2-encoded virulence systems.

112 ation of a number of fimbrial and Salmonella pathogenicity island 3 (SPI-3) and 5 genes, suggesting a

113 that Salmonella enterica serovar Typhimurium pathogenicity island 4 carries a type I secretion system

114 um requires a T6SS encoded within Salmonella pathogenicity island-6 (SPI-6).

115 Salmonella pathogenicity island 7 (SPI-7), found within some pathog

116 vi66 occurs in the cytotoxin-associated gene pathogenicity island, a genomic region known to be assoc

117 Streptococcus pneumoniae is an example of a pathogenicity island acquired through genetic recombinat

118 , is consistent with the notion that certain pathogenicity islands act cooperatively with the LEE isl

119 FIB plasmid harboring components of the ColV pathogenicity island and a multidrug resistance (MDR)-en

120 ses of H. pylori status, carriage of the cag pathogenicity island and assignment of H. pylori to phyl

121 These events are mediated by the cag pathogenicity island and by mitogen-activated protein ki

122 on the locus of enterocyte effacement (LEE) pathogenicity island and display high levels of multifun

123 is located between hrpR and avrE1 in the Hrp pathogenicity island and is carried in the functional cl

124 Virulence factors of H. pylori; the cag pathogenicity island and OipA affected IL-18 induction i

125 lbA and clbP, genes contained within the pks pathogenicity island and required for the synthesis of c

126 ew experimental methods, strain information, pathogenicity islands and external references that link

127 osa may be a useful strategy for identifying pathogenicity islands and novel virulence determinants.

128 mental conditions that induce the Salmonella pathogenicity islands and present a small RNA expression

129 med pUTI89 with many characteristics of UPEC pathogenicity islands and that likely arose due to horiz

130 adigm in the understanding of the biology of pathogenicity islands and therefore of bacterial pathoge

131 the Type III secretion system of Salmonella pathogenicity islands and two component signal transduct

132 re an initial characterization of this novel pathogenicity island, and we establish that it is stable

133 induction of bacteriophages, the movement of pathogenicity islands, and the expression of virulence f

134 elements such as genomic islands, prophages, pathogenicity islands, and the staphylococcal chromosoma

135 he EHEC locus of enterocyte effacement (LEE) pathogenicity island are known to contribute to this pat

136 Pathogenicity islands are sets of successive genes in a

137 m antibiotic class resistance and a putative pathogenicity island, arginine catabolic mobile element

138 and identify vacuolating cytotoxin A and cag pathogenicity island as the bacterial virulence determin

139 The tos operon is AT rich, resides on pathogenicity island aspV, and is not expressed under la

140 g the organism and strains harboring the cag pathogenicity island augment disease risk.

141 Bacterial virulence factors within the cag pathogenicity island, c-Abl tyrosine kinase, and interac

142 H. pylori strains containing the cag pathogenicity island (cag PAI) are associated with a hig

143 acaque model to study the effects of the cag pathogenicity island (cag PAI) on the H pylori host-path

144 igger inflammation in host cells via its cag pathogenicity island (cag PAI) type IV secretion system

145 H. pylori strains harboring the cag pathogenicity island (cag+), which encodes CagA and a ty

146 trains of Helicobacter pylori (Hp) possess a pathogenicity island, cag, that encodes the effector pro

147 However, 17 other cag pathogenicity island (cagPAI) genes, as well as some non

148 rboring the cag (cytotoxin-associated genes) pathogenicity island (cagPAI).

149 The T3SS is encoded in a pathogenicity island called the locus of enterocyte effa

150 oli are caused by isolates that also carry a pathogenicity island called the locus of enterocyte effa

151 effectors, are carried within a chromosomal pathogenicity island called the locus of enterocyte effa

152 conferring antibiotic resistance, as well as pathogenicity islands, capsule loci and other variable t

153 SPI4 is a 24-kb pathogenicity island containing six open reading frames,

154 The cag pathogenicity island contains genes encoding a secreted

155 anscriptional regulator encoded on the SPI-2 pathogenicity-island, determines the switch between thes

156 occal serine-rich repeat protein (PsrP) is a pathogenicity island-encoded adhesin that mediates attac

157 tion of this regulator, designated PerA (for pathogenicity island-encoded regulator), we first examin

158 which is unusually sheathed by the large cag-pathogenicity-island-encoded protein CagY.

159 The cag-pathogenicity-island-encoded type IV secretion system of

160 This pathogenicity island encodes and expresses staphylococca

161 The locus of enterocyte effacement (LEE) pathogenicity island encodes many genes required for the

162 terohaemorrhagic Escherichia coli harbours a pathogenicity island encoding a type 3 secretion system

163 Analysis of the T3SS2 pathogenicity island encoding the T3SS2 appeared to lack

164 enome is invariably associated with the high-pathogenicity island, encoding the siderophore yersiniab

165 Here we show that their multiple pathogenicity islands form together a coherently organiz

166 ing directly to promoters on the Francisella Pathogenicity Island (FPI) and positively regulating the

167 The Francisella tularensis pathogenicity island (FPI) encodes many proteins that ar

168 These factors activate Francisella pathogenicity island (FPI) gene expression, which is req

169 ion system (T6SS) encoded by the Francisella pathogenicity island (FPI) is critical for the virulence

170 F. novicida DeltaiglB, a Francisella pathogenicity island (FPI) mutant, is deficient in phago

171 Further, Francisella pathogenicity island (FPI) protein expression was induce

172 dependent upon the regulation of Francisella pathogenicity island (FPI) virulence genes, which is poo

173 virulence is dependent upon the Francisella pathogenicity island (FPI), a cluster of genes that we s

174 rotein encoded by the duplicated Francisella pathogenicity island (FPI).

175 in the iglABCD operon in the Francisella sp. pathogenicity island (FPI).

176 eplicates using the genes in the Francisella pathogenicity island (FPI).

177 n surrounding pmrA or within the Francisella pathogenicity island (FPI).

178 stems from genes encoded on the Francisella pathogenicity island (FPI).

179 tic elements; including an ArdB encoded on a pathogenicity island from uropathogenic Escherichia coli

180 imilarities in their genomic organization to pathogenicity islands from other bacteria and are likely

181 A loss of cag pathogenicity island function was observed in 3 reisolat

182 interleukin 8 from AGS cells (to detect cag pathogenicity island function), neutral red uptake (to d

183 A (SspA) complex and the DNA-binding protein pathogenicity island gene regulator (PigR)-activates FPI

184 073, homologs of the Shigella flexneri SHI-2 pathogenicity island gene shiA, suppress the host inflam

185 elements, but the natural deletion of 13 cag pathogenicity island genes and the truncation of CagA im

186 aken together, our data demonstrate that the pathogenicity island genes tested are essential for F. t

187 ups of motility and chemotaxis genes and for pathogenicity island genes, especially cagA, a predictor

188 nce factors including all of the Francisella pathogenicity island genes, LPS O-antigen synthetic gene

189 The LEE pathogenicity island has been acquired on multiple occas

190 Here we report that the staphylococcal pathogenicity islands have a dual role in gene transfer:

191 gulase-negative staphylococci, no associated pathogenicity islands have been found in the genome of S

192 Two genes within the T3SS pathogenicity island, herein named vttR(A) (locus tag A3

193 The Yersinia high-pathogenicity island (HPI) is common to multiple virulen

194 rinary E. coli isolates is the Yersinia high pathogenicity island (HPI), which directs the biosynthes

195 I secretion system encoded within Salmonella pathogenicity island I (SPI1).

196 Analysis of genetic variation in the LEE pathogenicity island identified 30 distinct LEE subtypes

197 esence of an incomplete or nonfunctional cag pathogenicity island in 18/276 genomes.

198 However, conservation of tomA on a pathogenicity island in S. acidiscabies and S. turgidisc

199 c class of lipoproteins (Lpls), encoded on a pathogenicity island in S. aureus, dampens the H2AX phos

200 thetic pathway and is located on a conserved pathogenicity island in S. scabies, S. turgidiscabies an

201 isparate genomic islands, defines VSP-1 as a pathogenicity island in V. cholerae, and implicates its

202 oded iron transport system is present within pathogenicity islands in all Shigella spp. and some path

203 The SaPIs are 14- to 17-kb mobile pathogenicity islands in staphylococci that carry genes

204 SaPI1 and SaPIbov1 are chromosomal pathogenicity islands in Staphylococcus aureus that carr

205 ther group we term Tn6022-like elements form pathogenicity islands in the Acinetobacter baumannii com

206 ate immune system utilizing genes encoding a pathogenicity island, including iglABCD, and instead uti

207 hin the locus of enterocyte effacement (LEE) pathogenicity island, including the adhesin Intimin and

208 zontal gene transfer (HGT) are the classical pathogenicity islands, including the integrative and con

209 whereas IL-18 protein was OipA dependent-cag pathogenicity island independent, indicating that OipA r

210 stric epithelial cells, mediated via the cag pathogenicity island, induces N-terminally truncated Del

211 Analysis of the chromosome region revealed a pathogenicity island inserted between two tRNA sequences

212 olysin expression, and expression of a novel pathogenicity island involved in alpha-ketoglutarate met

213 licobacter pylori strains containing the cag pathogenicity island is a risk factor for development of

214 ibe a mechanism by which an Escherichia coli pathogenicity island is preferentially packaged into a p

215 amidinotransferase enzyme located in the Hrp pathogenicity island, is required for systemic infection

216 However, cag pathogenicity island knockout strains of H. pylori had v

217 A unique cluster of genes was found in the pathogenicity island-like emm region that included a nov

218 he EPEC locus of enterocyte effacement (LEE) pathogenicity island, non-LEE-encoded effector H1 (NleH1

219 with unchanged cagY, we sequenced the entire pathogenicity island of 60 such isolates using single-mo

220 BM96) encoding a novel AT was located in the pathogenicity island of avian pathogenic Escherichia col

221 o the exchangeable effector locus in the Hrp pathogenicity island of DC3000D28E.

222 on the bi-functional RfaE enzyme and the Cag pathogenicity island of H. pylori, is accompanied by rep

223 e cupD gene cluster is located on the PAPI-1 pathogenicity island of strain PA14 and has probably bee

224 the yersiniabactin system found in the high-pathogenicity island of Yersinia sp. and is the first of

225 oxin (Proteus toxic agglutinin) and the high pathogenicity island of Yersinia spp.

226 and the SprA1(AS) RNA antitoxin are within a pathogenicity island on opposite strands and possess a 3

227 rease activity and is independent of the cag pathogenicity island or VacA.

228 th unknown function, which were localized to pathogenicity islands or APEC O1's large virulence plasm

229 PMI2596-2605 are contained within the high-pathogenicity island, originally described in Yersinia p

230 The Enterococcus faecalis pathogenicity island (PAI) encodes known virulence trait

231 e of a large virulence plasmid that houses a pathogenicity island (PAI) encoding a novel family of su

232 A 150-kb pathogenicity island (PAI) encoding several genes that c

233 jugative virulence plasmid harboring a 21-kb pathogenicity island (PAI) for growth in host macrophage

234 ional regulator was identified on the 153-kb pathogenicity island (PAI) found among virulent Enteroco

235 elicobacter pylori strains harboring the cag pathogenicity island (PAI) have been associated with mor

236 H. pylori strains bearing the cag pathogenicity island (PAI) induced higher levels of intr

237 ls infected with either cagA-negative or cag pathogenicity island (PAI) mutant.

238 es, at more than 11 Mb, and encodes a 100-kb pathogenicity island (PAI) shared with other plant-patho

239 the toxigenic vacA s1 allele, a complete cag pathogenicity island (PAI), cagA alleles containing mult

240 rry the Locus of Enterocyte Effacement (LEE) pathogenicity island (PAI), which encodes genes that med

241 e observed following infection with both cag pathogenicity island (PAI)-positive and -negative strain

242 tion is dependent on the presence of the cag pathogenicity island (PAI).

243 form T4SS, in addition to the status of cag pathogenicity island (PAI).

244 clustered in discrete genetic modules termed pathogenicity islands (PAI).

245 a strain deficient in the major pathway (cag pathogenicity island [PAI] encoded) for delivery of pept

246 in MM were used to determine distribution of pathogenicity islands (PAIs) across C. cellulans, which

247 Pathogenicity islands (PAIs) are a specific group of gen

248 thogen Pseudomonas viridiflava possesses two pathogenicity islands (PAIs) that share many gene homolo

249 Our results suggest that the pathogenicity island PAPI-1 may have evolved by acquisit

250 The pathogenicity island PAPI-1 of strain PA14 is a cluster

251 p2, is similar to the Pseudomonas aeruginosa pathogenicity island PAPI.

252 ns, integrative conjugative elements (ICEs), pathogenicity islands (PIs), prophages, and gene cassett

253 Escherichia coli can carry the pathogenicity island pks, which encodes a set of enzymes

254 esin encoded in the Streptococcus pneumoniae pathogenicity island psrP-secY2A2.

255 While the acquisition of the plasmid-encoded pathogenicity island (pXO1) and capsule genes (pXO2) rep

256 tructural gene, bslA, is located on the pXO1 pathogenicity island (pXO1-90) and bslA expression is bo

257 genes are indeed located within the deleted pathogenicity island region.

258 One explanation for this discrepancy is that pathogenicity islands, regions of DNA found in some stra

259 The Francisella pathogenicity island, required for bacterial phagosome e

260 The Staphylococcus aureus pathogenicity island SaPI1 carries the gene for the toxi

261 thesis operon, the betA-betB operon, and the pathogenicity island, SaPI5, while virulence genes were

262 These genes, along with a putative pathogenicity island (SaPIBov) present uniquely in the c

263 Staphylococcus aureus pathogenicity islands (SaPIs) are genetic elements that

264 Staphylococcal pathogenicity islands (SaPIs) are the prototypical membe

265 that induce the cycle of some Staphylococcal pathogenicity islands (SaPIs) by binding to the SaPI-enc

266 Staphylococcal pathogenicity islands (SaPIs) carry superantigen and res

267 r repressor encoded by Staphylococcus aureus pathogenicity islands (SaPIs) that maintains integration

268 e clinically important Staphylococcus aureus pathogenicity islands (SaPIs) use this tactic to spread

269 Staphylococcus aureus pathogenicity islands (SaPIs), such as SaPI1, exploit sp

270 ansfer agents (GTAs), and the staphylococcal pathogenicity islands (SaPIs), the primary focus of this

271 ghly mobile phage satellites, staphylococcal pathogenicity islands (SaPIs), which carry and dissemina

272 ation of genetic elements known as S. aureus pathogenicity islands (SaPIs), which carry genes for sup

273 d virulence factors are encoded on S. aureus pathogenicity islands (SaPIs).

274 cells through the mobilization of S. aureus pathogenicity islands (SaPIs).

275 first evidence of a composite S. epidermidis pathogenicity island (SePI), the product of multiple ins

276 The pgm locus encodes, within a high-pathogenicity island, siderophore biosynthesis genes tha

277 sociated with lower expression of Salmonella pathogenicity island (SPI) 1 genes in S.

278 ystem SsrA/B, which is located on Salmonella Pathogenicity Island (SPI) 2.

279 Horizontal acquisition of Salmonella Pathogenicity Island (SPI)-2 permitted the expansion of

280 ion of genes encoded within and outside of a pathogenicity island (SPI-2), which is required for syst

281 la enterica serovar Typhimurium harbors five pathogenicity islands (SPI) required for infection in ve

282 The two T3SS are encoded on separate pathogenicity islands, SPI-1 and -2, with SPI-1 more str

283 tory cross-talk between two major Salmonella pathogenicity islands, SPI-1 and SPI-2, was responsible

284 557 and two neighbouring genes, located on a pathogenicity island termed SPI-16, resemble genes of th

285 n formation are encoded within a chromosomal pathogenicity island termed the locus of enterocyte effa

286 25-RE, which had a 15-kb deletion in the cag pathogenicity island that truncated CagA and eliminated

287 age therapy for bovine mastitis, we observed pathogenicity island transfer between S. aureus and L. m

288 iffering at 113 gene loci, including the cag pathogenicity island virulence genes.

289 Vibrio Pathogenicity Island (VPI)-1 was present; however, SXT/R

290 tor AphA at the tcpPH promoter on the Vibrio pathogenicity island (VPI).

291 the PhoPQ two-component system nor the SPI-2 pathogenicity island was required for lethal S. Typhi in

292 tuent that increases disease risk is the cag pathogenicity island, which encodes a secretion system t

293 risk is the cytotoxin-associated gene (cag) pathogenicity island, which encodes a secretion system t

294 key virulence factor of H. pylori is the Cag pathogenicity island, which encodes a type IV secretion

295 ments cancer risk is the strain-specific cag pathogenicity island, which encodes a type IV secretion

296 icobacter pylori strains that harbor the cag pathogenicity island, which encodes a type IV secretion

297 Virulence factors include the cag pathogenicity island, which induces proinflammatory, pro

298 H. pylori strains that possess the cag pathogenicity island, which translocates CagA into the h

299 One cancer-linked locus is the cag pathogenicity island, which translocates components of p

300 , EHEC represses flagellar genes and the LEE pathogenicity island while it activates the acid fitness