ライフサイエンスコーパス: pathological feature

1 obliterans (BO) representing the predominant pathological feature.

2 mechanisms that may be responsible for this pathological feature.

3 etic etiologies and overlapping clinical and pathological features.

4 rs shared a similar constellation of adverse pathological features.

5 ingioma subgroups with distinct clinical and pathological features.

6 gnisable variants with distinct clinical and pathological features.

7 ts most frequently with similar clinical and pathological features.

8 Huntington's or Prion diseases share similar pathological features.

9 mas with distinct clinical presentations and pathological features.

10 issue localization of deposits and for major pathological features.

11 nd the layers that were most affected by the pathological features.

12 ctly model the human disease, it shares many pathological features.

13 disease with an expanding definition of its pathological features.

14 description of stage-dependent sequences of pathological features.

15 mation of alpha-syn are considered to be key pathological features.

16 ffending antigen, bronchoalveolar lavage and pathological features.

17 ich oligodendrocyte cell-death is one of the pathological features.

18 included lesions with benign and dysplastic pathological features.

19 and cardiovascular involvement were dominant pathological features.

20 nating in larger prostates present favorable pathological features.

21 k, survival, and clinical, radiographic, and pathological features.

22 ination with the progressive nature of other pathological features, aged mdx muscle tissue provides r

23 mes with overlapping clinical, molecular and pathological features, all of which challenge the design

24 lin were compared with RS alone and clinical-pathological features alone using likelihood ratio tests

25 represents the greatest risk factor for CTE pathological features, although clinicopathological corr

26 elevated extracellular glutamate is a common pathological feature among epilepsies with different eti

27 Shared pathological features among muscular dystrophies include

28 himeric model for AD displays human-specific pathological features and allows the analysis of differe

29 These dementias share common pathological features and are referred to as Lewy body d

30 line M(1) receptors (M(1)Rs) reduces AD-like pathological features and enhances cognition in AD trans

31 ice were studied at different ages for renal pathological features and function.

32 special stains, and IHC to characterize the pathological features and investigate the pathogenesis o

33 xacerbating AD-related cognitive decline and pathological features and provide critical preclinical e

34 elation of Rig-G expression with key clinico-pathological features and survival outcomes in a multi-s

35 the development of hallmark amyloid and tau pathological features and that long-term expression of t

36 that have both dysplastic and proliferative pathological features, and neither the International Wor

37 s, absence of specific clinical, imaging, or pathological features, and ongoing dependence for diagno

38 These pathological features are also relevant to other common

39 The defining pathological features are fluid-filled cysts developing

40 teristic of Niemann-Pick type C disease, the pathological features are not well understood.

41 en segment function is disrupted, a range of pathological features are presented.

42 These pathological features are reproduced in a model of chron

43 translational models that reproduce the core pathological features are urgently needed to facilitate

44 S1P(1) agonism alone reduced pathological features as did fingolimod (maximally lymph

45 les (NFT), is considered the most predictive pathological feature associated with cognitive status in

46 Neuritic dystrophy is one of the important pathological features associated with amyloid plaques in

47 g is important as it may explain some of the pathological features associated with changes in NAT1 ex

48 s to date, we characterized the clinical and pathological features associated with hippocampal sclero

49 d-skull brain injury model that mirrors some pathological features associated with mild TBI in humans

50 1R) reduces food intake and improves several pathological features associated with obesity, such as d

51 of misfolded proteins in the cytosol are key pathological features associated with Parkinson's diseas

52 oglycan is sufficient to explain all complex pathological features associated with these diseases is

53 improves survival in patients with high-risk pathological features at radical prostatectomy at the co

54 ionship between in vivo imaging measures and pathological features, at the single subject level, rema

55 ors recently recognized common molecular and pathological features between the 2 conditions.

56 al syndrome with characteristic clinical and pathological features but unknown etiology.

57 ice exhibit enhanced amyloid and tau-related pathological features by the age of 15 months, in stark

58 e with ATXN1[30Q]-D776-induced disease share pathological features caused by ATXN1[82Q] having an exp

59 reatment with IL-13-PE can reverse important pathological features caused by inhalation of silica par

60 e well tolerated, producing no behavioral or pathological features characteristic of ALS/FTD and only

61 Both diseases share clinical and pathological features characteristic of excessive allerg

62 ferents from the bladder and distal colon, a pathological feature common to alpha-synucleinopathies i

63 uclein (aSyn) misfolding and aggregation are pathological features common to several neurodegenerativ

64 spinal cord exhibited many key clinical and pathological features consistent with human ALS disease.

65 Brain insulin resistance is a key pathological feature contributing to obesity, diabetes,

66 Clinical, radiological and pathological feature define CLIPPERS syndrome and are di

67 Statistical analysis of clinical and pathological features demonstrated that the expression o

68 ermediate filaments (IFs) represent the main pathological feature detected in neurons and other cell

69 Among other pathological features, DMD muscles show severely derange

70 04 segmented anatomical structures and 8,329 pathological features from 1,772 slit-lamp images.

71 Diverse pathological features have been identified, and their di

72 on, with synaptic dysfunction being an early pathological feature in aging and disease.

73 Defects in axonal transport are an early pathological feature in Alzheimer's disease and defectiv

74 Disruption to axonal transport is an early pathological feature in Alzheimer's disease.

75 The hallmark pathological feature in most cases of ALS is nuclear dep

76 ed, and although demyelination is a hallmark pathological feature in MS, it is unclear to what extent

77 Aberrant protein aggregation is a dominant pathological feature in neurodegenerative diseases.

78 We revealed the same pathological features in a mouse model of human Adrenomy

79 Pathological features in Alzheimer's brains include mito

80 estigate several inflammatory and structural pathological features in bronchial biopsies of severe as

81 Somatostatin (SST) deficits are common pathological features in depression and other neurologic

82 ix, inflammation and fibrosis are the common pathological features in DMD, the underlying mechanisms

83 the need to evaluate the neurocognitive and pathological features in female carriers of the fragile

84 igenesis and metastasis, which resembles the pathological features in human patients.

85 nto the striatum initiated Parkinsonian-like pathological features in mice.

86 cognitive dysfunction, which are invariable pathological features in patients with Alzheimer's disea

87 of the prefrontal cortex (PFC) are prevalent pathological features in schizophrenia (SZ).

88 anatomical structures and the annotation of pathological features in slit-lamp images, and the use o

89 terial lipopolysaccharide, modulates AD-like pathological features in the 3xTg-AD mouse model and pro

90 oach may be applicable to a diverse range of pathological features in the retina and other organs.

91 Pathological features include loss of myocytes and fibro

92 Hallmark pathological features include T-cell mediated inflammato

93 Additional pathological features included cortical Lewy bodies, bra

94 se accurately recapitulate all the key human pathological features including brain enlargement, corti

95 ews were performed to correlate clinical and pathological features (including detailed pathological f

96 D) is characterized by multiple, intertwined pathological features, including amyloid-beta (Abeta) ag

97 dult-onset inherited myopathies with similar pathological features, including hereditary inclusion bo

98 Cav-1 knockout retinas exhibited additional pathological features, including i) eNOS-independent enl

99 Both diseases share multiple pathological features, including overexpression of C-X-C

100 However, the molecular cause of many pathological features, including the frequently observed

101 tion and neuroinflammation are two prominent pathological features increasingly realized as important

102 The pathological features induced by RSV infection in HIS mi

103 ne lymphoma (MGZL) is extremely rare and has pathological features intermediate between NSHL and PMBL

104 (finger flexor and quadriceps weakness) and pathological features (invasion of myofibres by cytotoxi

105 prominent glial reactions, but whether this pathological feature is due primarily to cell proliferat

106 ess SMCs; however, a mechanism linking these pathological features is lacking.

107 rlie disparate claims about its clinical and pathological features, leading to confusion among the pu

108 dependently attenuated clinical symptoms and pathological features (leukocyte infiltration and demyel

109 tween BMI and risk of CRC by major molecular pathological features: microsatellite instability (MSI),

110 y-onset, profound hearing deficits and other pathological features mimicking human laminopathy associ

111 It is a pathological feature observed in certain tumors, referre

112 synthesis was required for induction of all pathological features observed both in vitro and in vivo

113 The major pathological features observed in post-mortem tissue fro

114 We describe here the clinical and pathological features observed in two unrelated females,

115 , and TDP-43 mislocalization in MNs is a key pathological feature of >95% of ALS cases.

116 regation of alpha-synuclein (alpha-syn) is a pathological feature of a number of neurodegenerative co

117 ngs suggest that weight loss is an intrinsic pathological feature of Abeta accumulation and identify

118 Endocytic dysfunction is a pathological feature of AD, and endocytosis of the amylo

119 t showed abnormal activation of GSK-3beta, a pathological feature of AD.

120 A key pathological feature of ALS is cytoplasmically mislocali

121 icate that activated caspase 3 defines a new pathological feature of ALS with intermediate-length ata

122 o evidence of muscle denervation, a cardinal pathological feature of ALS.

123 itive element transcript expression, a novel pathological feature of ALS/FTLD.

124 ta peptides (Abeta) in the brain is a common pathological feature of Alzheimer disease (AD).

125 al plaques and the cerebral vasculature is a pathological feature of Alzheimer disease and related di

126 f beta-amyloid (Abeta) deposits is a primary pathological feature of Alzheimer disease that is correl

127 Senile plaques are a prominent pathological feature of Alzheimer's disease (AD), but li

128 yloid beta-protein (Abeta) in brain is a key pathological feature of Alzheimer's disease and related

129 Accumulation of phosphorylated tau is a key pathological feature of Alzheimer's disease.

130 Insulitis is an important pathological feature of autoimmune diabetes; however, me

131 Metabolic reprogramming is a pathological feature of cancer and a driver of tumor cel

132 pH in the tumor micromilieu is a recognized pathological feature of cancer.

133 Interstitial fibrosis, a common pathological feature of chronic kidney diseases, is ofte

134 Intestinal inflammation is the central pathological feature of colitis and the inflammatory bow

135 One main pathological feature of COPD is the loss of functional a

136 However, bone marrow failure is the primary pathological feature of FA that becomes evident in 70-80

137 not primarily due to MSN loss, the defining pathological feature of HD.

138 as cross-beta sheet amyloids are a defining pathological feature of infectious prion disorders and a

139 fy rapid complex I reactivation as a central pathological feature of ischemia-reperfusion injury and

140 ranslation initiation factor eIF2alpha, is a pathological feature of many neurodegenerative diseases

141 Neuroinflammation is a common pathological feature of many neurodegenerative diseases,

142 Axon degeneration is a critical pathological feature of many neurodegenerative diseases.

143 Oxidative stress is a pathological feature of many neurological disorders; the

144 3 is a major component, are a characteristic pathological feature of most ALS and FTD patients.

145 Fibrosis is a pathological feature of most chronic inflammatory diseas

146 Protein aggregates are a common pathological feature of most neurodegenerative diseases

147 on-hematological conditions and is a central pathological feature of myelofibrosis.

148 Protein aggregates are a common pathological feature of neurodegenerative diseases and s

149 nerve cells and glial cells is the defining pathological feature of neurodegenerative diseases calle

150 Astrocytic necrosis is a prominent pathological feature of neuromyelitis optica (NMO) lesio

151 A pathological feature of Parkinson's disease (PD) is Lewy

152 demonstration that dopamine loss is the key pathological feature of Parkinson's disease (PD), and th

153 Striatal spine loss is a key pathological feature of Parkinson's disease (PD).

154 rebral amyloid angiopathy (CAA), is a common pathological feature of patients with Alzheimer's diseas

155 ession of SV2C within the basal ganglia is a pathological feature of PD.

156 osis of interstitial trophoblasts is a novel pathological feature of preeclampsia and SGA.

157 ascular wall is a key currently irreversible pathological feature of pulmonary hypertension, a progre

158 Activated microglia represent a common pathological feature of several neurodegenerative diseas

159 erates oligomeric intermediates, is a common pathological feature of several neurodegenerative disord

160 is induced by neuronal damage and is also a pathological feature of the major aging-related neurodeg

161 A common pathological feature of these diseases is the accumulati

162 aberrant TDP-43 cross-linking is a prominent pathological feature of this disease.

163 ecrete sufficient quantities of insulin is a pathological feature of type-1 and type-2 diabetes, and

164 ore, in this system we recapitulated another pathological feature of VM, the paucity of pericytes aro

165 to delineate clinically relevant genomic and pathological features of a large panel of PSC-associated

166 expression and pulmonary function linked to pathological features of acute lung injury (ALI) and acu

167 ts within the TREM locus are associated with pathological features of AD and aging-related cognitive

168 These H(2)O(2)(-)-induced pathological features of AD in GiDs are consistently rec

169 centers of the observed type are common, key pathological features of AD may arise on a very short ti

170 in those with diabetes is mediated by excess pathological features of AD or other related abnormaliti

171 Tau and beta-amyloid (Abeta), the primary pathological features of AD, are associated with both ob

172 M locus in relation to cognitive decline and pathological features of AD.

173 The Ctrp5(+/-) mice, which have most of the pathological features of age-related macular degeneratio

174 This review examines the pathological features of aggressive bladder cancer and c

175 s and ultimately progressed with clinical or pathological features of AIDS.

176 tion, hyperresponsiveness, and remodeling as pathological features of allergic asthma provoked by hou

177 alpha-synuclein (alpha-syn), are predominant pathological features of Alzheimer's disease (AD) and Pa

178 The hallmark pathological features of Alzheimer's disease (AD) brains

179 Early pathological features of Alzheimer's disease (AD) includ

180 ITRM1-knockout iPSCs spontaneously developed pathological features of Alzheimer's disease (AD), inclu

181 plaque-localized neuro-inflammation are key pathological features of Alzheimer's disease (AD).

182 sfunction and the loss of synapses are early pathological features of Alzheimer's disease (AD).

183 tor associated with accumulation of two core pathological features of Alzheimer's disease (AD): tau a

184 ion that null mutations in Atp13a2 can cause pathological features of both diseases in the same organ

185 tive stress and energy deficit are important pathological features of calpainopathy and possibly repr

186 eterogeneity, and has been linked to clinico-pathological features of cancer.

187 y genes and pathways underlying the specific pathological features of cardiomyopathies.

188 Although the pathological features of clinically characterized Haller

189 All pathological features of collagen-induced arthritis (CIA

190 characterise the clinical, physiological and pathological features of copper-deficient peripheral neu

191 Descriptions of the pathological features of coronavirus disease-2019 (COVID

192 ases is valuable to gain insights into early pathological features of corticobasal degeneration and i

193 Our studies show that pathological features of DBA are recapitulated by iPSCs,

194 the hippocampus, recapitulating several key pathological features of dementia observed in human pati

195 and is one of the first areas to express the pathological features of dementia.

196 n in the 30% hypomorphs almost abolishes the pathological features of diabetic nephropathy, although

197 ALS patients and SOD1(G93A) mice, the first pathological features of disease manifest at the neuromu

198 this monkey model mimicked the clinical and pathological features of early mild to moderate S. aureu

199 asts, were fully functional and mirrored the pathological features of EBS-MD myofibers, including the

200 la enterica serotype Typhimurium and exhibit pathological features of enteric salmonellosis that clos

201 Pseudomonas exotoxin (IL-13-PE) might affect pathological features of experimental silicosis.

202 sion, which is primarily responsible for the pathological features of FXS .

203 otentially mimic essential physiological and pathological features of GBM and BBB.

204 he first viable vertebrate model sharing key pathological features of GD in both neuronal and non-neu

205 but regardless of resolution of the cardinal pathological features of GM2 gangliosidosis, a point is

206 in organotypic raft cultures, mirroring the pathological features of higher-grade intraepithelial le

207 These models recapitulate key pathological features of human diseases and provide acce

208 n1 mouse model effectively recapitulates the pathological features of human FAN1 deficiency.

209 edium-sized blood vessels, represent salient pathological features of human rickettsioses, the intera

210 However, the characteristic pathological features of INCL were almost completely abs

211 Changes in pathological features of intermediate AMD eyes were dete

212 immunocytochemical methods to determine the pathological features of intranuclear inclusions in astr

213 replicates hearing loss and the clinical and pathological features of LF will significantly increase

214 t Atm signaling played critical roles in the pathological features of liver failure.

215 y mice faithfully recapitulated clinical and pathological features of meningeal infiltration seen in

216 ugar and its overconsumption exacerbates key pathological features of metabolic syndrome.

217 cohort often, but not exclusively, exhibited pathological features of microvasculitis and ischaemia;

218 Here we define the clinical and pathological features of MN and describe the experimenta

219 ingly recognised, however, that clinical and pathological features of MSA are broader than previously

220 to demyelination and axonal loss, which are pathological features of multiple sclerosis (MS), the mo

221 Nevertheless, studies of the pathological features of multiple sclerosis and NMOSDs h

222 ThT also suppressed pathological features of mutant metastable proteins and

223 Microgliosis and astrogliosis are standard pathological features of neurodegenerative disease.

224 ssion with doxycycline on the NFT-associated pathological features of neuronal system deafferentation

225 with AQP4 plausibly account for the diverse pathological features of NMO: edema, inflammation, demye

226 immunocytochemical methods to determine the pathological features of nuclear and/or cytoplasmic incl

227 The hallmark pathological features of Parkinson's disease are Lewy bo

228 neurons in the locus coeruleus are important pathological features of Parkinson's disease.

229 We evaluated clinical, radiological and pathological features of patients referred for suspected

230 SVAS iPSC-SMCs recapitulate key pathological features of patients with SVAS and may prov

231 One of the main pathological features of PD is loss of dopamine neurons

232 y undiagnosed CC and review the clinical and pathological features of previously reported cases.

233 rtex spongiform change, one of the classical pathological features of prion disease, resolves in prio

234 of auditory stimuli was associated with core pathological features of schizophrenia, increasing confi

235 Importantly, key pathological features of smoking-associated lung disease

236 ropose that tmTNF is responsible for the key pathological features of SpA.

237 cells of SSc patients may underlie the main pathological features of SSc including autoimmunity, vas

238 various approaches attempting to tackle the pathological features of synucleinopathies, antibody-bas

239 Notably, the pathological features of tau pathology in these diseases

240 udy reveals that glaucoma displays signature pathological features of tauopathies, including tau accu

241 geting antibody to rodents reduces or delays pathological features of TBI.

242 n of CSF1 expression was consistent with the pathological features of tenosynovial giant-cell tumor.

243 ls results in an exacerbation of all 3 major pathological features of the AD phenotype: memory defici

244 al dysfunction and synaptic damage are early pathological features of the Alzheimer's disease-affecte

245 rstanding of the mdx mouse model by tracking pathological features of the disease throughout life.

246 s for FD that recapitulate the molecular and pathological features of the disease.

247 h dementia severity when compared with other pathological features of the disease.

248 ease type 1a) were found to recapitulate key pathological features of the diseases affecting the pati

249 We propose that major pathological features of the DM brain result from disrup

250 fficient extraction of the morphological and pathological features of the entire aortic volume.

251 Although the clinical and pathological features of the GFAP(-/-)Vimentin(-/-)PPT1(

252 This model demonstrates pathological features of the human disease, including in

253 s) that faithfully recapitulate the clinical-pathological features of the human disease.

254 elial cells and reproduces many clinical and pathological features of the more severe forms of diseas

255 e disease in mice resembling biochemical and pathological features of the mucopolysaccharidoses and p

256 nd pathological features (including detailed pathological features of the parenchymal margin) with re

257 Clinical and pathological features of the patients were analyzed.

258 these label-retaining cells exhibit all the pathological features of the primary disease.

259 HCC, especially in patients with pejorative pathological features of the primary tumor that could in

260 array studies, as well as with clinical and pathological features of the tumors and relapse and surv

261 Herein, we review the pathological features of these central nervous system in

262 We describe the clinical and pathological features of these infections and the phylog

263 unohistochemistry and evaluated clinical and pathological features of these patients.

264 ng that altered AV biogenesis is part of the pathological features of this disease.

265 blockade of ST2L with an mAb attenuated key pathological features of this model.

266 ng of a single factor to eliminate c9FTD/ALS pathological features offers advantages over approaches

267 hypotonia and muscle weakness, and specific pathological features on muscle biopsy.

268 e scored by two experienced pathologists for pathological features or analysed by image analysis and

269 sess graft function, it does not reflect the pathological features or progressive nature of the disea

270 tion within the myocardium and driving major pathological features pathognomonic in arrhythmogenic ca

271 Although they share common pathological features, protein aggregates form in differ

272 nd extracellular Abeta deposits are the main pathological feature recapitulated by mouse models, cell

273 recise molecular mechanisms underlying these pathological features remain elusive.

274 The latter group had pathological features resembling those with a final clin

275 hed, mainly for HHV-6A, which reproduce some pathological features seen in humans.

276 Further, they had pathological features similar to those of human triple-n

277 Pathological features such as HLA class I hyperexpressio

278 Because of its distinct clinical and pathological features, such as lack of expression of CD2

279 :Rv3242c M. marinum strains showed prominent pathological features, such as severe emaciation, skin l

280 asomnia with sleep breathing dysfunction and pathological features suggesting a tauopathy.

281 ritis (C3GN) - have overlapping clinical and pathological features suggestive of a disease continuum.

282 The only pathological feature that could potentially explain this

283 aetiology, TDP-43 proteinopathy is a common pathological feature that is observed in >95% of ALS and

284 cyte progenitors and demyelination are major pathological features that are particularly pronounced i

285 rtical impact model to identify the specific pathological features that give rise to the diffusion te

286 asmic reticulum (ER) stress is among several pathological features that underlie beta-cell failure in

287 Consistent with these distinct pathological features, the ErbB2DeltaEx16 tumors exhibit

288 tramyocardial lipid accumulation are the key pathological features, triggering cellular signalling an

289 aracterized by a higher incidence of adverse pathological features, unique gene expression profiles a

290 e present with uniform clinical, genetic and pathological features, we further propose the disorder b

291 at onset, disease duration, and clinical and pathological features were collected when available.

292 defined HP, and clinical, radiographic, and pathological features were described.

293 t have distinct biological, biochemical, and pathological features were identified in transgenic mice

294 progression and early cognitive decline; the pathological features were striking and reminiscent of d

295 The predominant pathological features were that of drug induced liver in

296 This study evaluated the pathological features when exogenous alpha-synuclein pre

297 lar degeneration shares several clinical and pathological features with AD, the measurements were the

298 sue, and then correlate these discriminative pathological features with corresponding spectral signat

299 r neuron survival, and Scyl1(-/-) mice share pathological features with many human neurodegenerative

300 far) along with a review of its imaging and pathological features, with treatment options.