ライフサイエンスコーパス: patient

1 y (n = 5) and diseased (n = 5) sites of each patient.

2 the Oswestry disability index scores in LDH patients.

3 inflammatory respiratory failure in COVID-19 patients.

4 t of clinical outcomes in heart failure (HF) patients.

5 e included 5,195 AALL0331 and 3,001 AALL0232 patients.

6 RASGRP1 is frequently overexpressed in T-ALL patients.

7 side antibodies, and serum antibodies of GBS patients.

8 inflammation profiles in subpopulation of TB patients.

9 ve pain management strategy in this group of patients.

10 Soft tissue healing was uneventful in all patients.

11 exercise versus a HB exercise program for HD patients.

12 erapy helping in a better stratification GBM patients.

13 n of subretinal fluid was achieved in 93% of patients.

14 isk factors of transfer and mortality in IHT patients.

15 sed HB surface antigen at levels relevant to patients.

16 nd hemodynamic instability in critically ill patients.

17 e BM plasma samples from MM compared to MGUS patients.

18 CNS relapse occurred in only 4 patients.

19 Management was affected in 104 of 182 (57%) patients.

20 was achieved by 20 (47%, 95% CI 31-62) of 43 patients.

21 lty had a stronger adverse impact on younger patients.

22 may also affect the nursing care quality for patients.

23 Patients 10 to 17 years of age who had received stable l

24 All patients (100%) received prior ICIs targeting the PD-1 p

25 Six of 143 died (4%) vs 362 of 2095 patients (17%, P < .001).

26 3; P = .02); RB1 mutation (seen in 19 of 103 patients, 18.4%) was associated with peritoneal carcinom

27 A total of 92 eyes of 47 patients (31 females) with mean age of 48.0 +/- 18.0 yea

28 Of 527 ineligible patients, 386 had full DST, of which 246 were resistant

29 Death occurred in 7 patients (4%) who received SNF472 and 5 patients (6%) wh

30 TP53 mutation (seen in 58 of 103 patients, 56%) was associated with lymphadenopathy (rela

31 in 7 patients (4%) who received SNF472 and 5 patients (6%) who received placebo.

32 linical trials of therapy that included 3074 patients, 9 were case series, and 3 were cohort studies.

33 However, patient access remains limited because of restricted ins

34 Clustering patients according to their PK parameter values revealed

35 l communities from EDC and sputum samples of patients according to type 2 (T2)-asthma endotypes.

36 MRI was performed in all patients after having presented at our department for th

37 res of proximal and distal motor function in patients after hemispherotomy.

38 the outcomes of interhospital transfer (IHT) patients after pancreatectomy, describe the characterist

39 Patients (aged >=16 years) who were being treated non-op

40 In summary, we present a method for ordering patients along a trajectory of LOAD disease progression

41 In 72% of the patients an invasive evaluation was performed, in which

42 reatment of anemia in chronic kidney disease patients and may also be beneficial for the treatment of

43 nt contractures in approximately half of the patients and no myotonia.

44 Also, in a comparison made between normal patients and patients with dissection, right CCA (p = 0.

45 in monogenic PID occurred in 10.3% of these patients, and a Bayesian approach (BeviMed(4)) identifie

46 were 0.70, 0.75, and 0.64 for Asians, black patients, and Hispanics, respectively.

47 id arthritis (RA), a substantial minority of patients are exposed to multiple DMARDs without necessar

48 e, and postoperative care for these youngest patients are paramount.

49 Sixty intrabony defects in AgP and CP patients associated with >= 6 mm residual probing pocket

50 nd in the peripheral blood CD4(+) T cells of patients at all stages of HIV-1 infection.

51 is particularly significant because it puts patients at risk by reducing the capacity of nurses to p

52 as a complication of MMCR surgery with their patients before surgery.

53 reast cancer at age <= 40 years and enrolled patients between 2006 and 2016 (N = 1,302).

54 We prospectively enrolled 121 patients between October 2015 and January 2019.

55 ADC potentially reflects renal injury in RVD patients, but does not change in response to medical or

56 We used cluster analysis to group patients by the dose, recency, duration, and continuity

57 The major cause of death in prostate cancer patients can be attributed to metastatic spread of disea

58 terventions was low or very low, intensified patient care and rechallenge with the same or a differen

59 ined renal tumors and their association with patient clinical and genetic characteristics.

60 Important patient clinical determinants of self-care included cogn

61 owth factor 12, with differential effects in patients compared to controls.

62 athic pulmonary arterial hypertension (IPAH) patients compared to those from healthy controls.

63 an acute phase from DENV-infected pediatric patients correlates with severe disease development.

64 of care in managing coronavirus disease 2019 patients, current and anticipated resource demands, and

65 Patient demographics, tissue characteristics, intraopera

66 we investigated the structural effects of a patient-derived CF-phenotypic mutation, E217G, located i

67 measure CFTR function using cystic fibrosis patient-derived iPSC lines before and after correction o

68 hromatin immunoprecipitation sequencing of a patient-derived xenograft.

69 Twenty-four of 44 (55%) patients developed moderate to severe hypophosphataemia

70 in situ subtypes) collected from 54 BI-ALCL patients diagnosed through the French Lymphopath network

71 teria resulted in a stage change for >35% of patients diagnosed with invasive breast cancer and refin

72 developed incident TB within 1 year of index patient diagnosis.

73 Of 18 102 patients discharged, 3461 (20%) died within 1 year.

74 SCA7 patients displayed increased poly(ADP-ribose) in cerebel

75 It included 205 eyes from 205 patients distributed in 82 normal corneas, 40 early-stag

76 In addition, a substantial proportion of patients do not respond to therapy despite being infecte

77 Patients exercised at both absolute (0, 5, 10, 15 W) and

78 and two systematic reviews describing older patients' experiences of care in acute hospital settings

79 using data from CT examinations of pediatric patients (February to December 2018).

80 Twenty-one studies (2'930 patients, five RCT, 16 observational studies) were retai

81 he primary imaging modalities used to select patients for endovascular thrombectomy (EVT) are noncont

82 ified 123 patients for the CPI group and 147 patients for the control (CC) group.

83 We identified 123 patients for the CPI group and 147 patients for the cont

84 migraine and was safe and well tolerated in patients for whom multiple previous standard-of-care pre

85 One hundred twenty-two patients from 7 medical centers in the United States wer

86 c data from The Cancer Genome Atlas from 110 patients from five institutions with lower-grade gliomas

87 easing, driven primarily by increased use in patients greater than 12 years old.

88 tinib induction therapy (day 85), 29% of the patients had a molecular response, and this percentage i

89 Only 0.86% of patients had an HZ-related hospitalization.

90 The whole group of antipsychotic-naive patients had lower levels of GABA in dorsal ACC (p = .03

91 All patients had neonatal/early-onset diabetes, severe micro

92 hing hospitals for both hospital-level (safe patient handling programs and organizational practices)

93 index >30), and depressive symptoms (2-item Patient Health Questionnaire score >=2) per quarter-year

94 ntibody sequences across SARS-CoV-2-infected patients, highlighting stereotyped naive responses to th

95 dentification that lack rapid testing of the patient immune response, impeding clinicians from provid

96 ted with EVALI in a convenience sample of 51 patients in 16 states across the United States.

97 ) before PCI impacts on outcomes among these patients in contemporary practice remains unclear.

98 method for capturing RBC images from the SCD patients in normoxia and hypoxia conditions.

99 in the secukinumab group and six (1%) of 427 patients in the adalimumab group had serious infections.

100 ate was lower than that frequently quoted to patients in the clinic.

101 60 (57%) of 104 patients in the placebo group, 63 (66%) of 96 in the ixe

102 OCT scans improved by 1 step in 10 patients in the PPV group.

103 Three patients in the RMA group developed relapse.

104 Seven (2%) of 426 patients in the secukinumab group and six (1%) of 427 pa

105 year overall survival estimate of the 16 062 patients in the study cohort was 62.3% (95% CI 59.7-64.4

106 genation to support critically ill, poisoned patients in the United States is increasing, driven prim

107 20 February and 15 March 2020 from infected patients in Washington state in the United States.

108 that anti-ADAMTS13 autoantibodies from iTTP patients induce an open ADAMTS13 conformation.

109 nd collected qualitative data from staff and patient interviews and practice observation.

110 iated with studies of patient pathways using patient interviews.

111 f machine learning algorithms to cluster the patients into discriminative groups to improve prognosis

112 Using patient-level claims data from US commercial and Medicar

113 larly relevant to treatment tolerability for patients living with indolent disease.

114 s needed to determine if there is sufficient patient load to maintain such a service.

115 Patients managed with CCY did not differ in age, insuran

116 Of 614 patients (median age 69 years, (IQR 25) and 62% male), 3

117 Adverse events were reported in 58.4% of patients; most (94.4%) were mild-to-moderate in severity

118 ose of 100 mg twice daily, and to paediatric patients mostly at a dose of 100 mg/m(2) (maximum of 100

119 ve as a predictive tool for graft failure in patients (n = 181) who received a kidney transplant in O

120 A subset of patients (n = 98) were selected for a WES-only pipeline

121 In MS patients, Ndst1 is also found overexpressed in oligodend

122 or surgery, the reasons for inpatient FA in patients older than 3.8 years included the lack of avail

123 In conclusion, patients on aspirin and clopidogrel had a higher inciden

124 nvestigate treatment outcomes among PWID and patients on OST in comparison to control cohorts.

125 ics were not significantly different between patients on the Beat AML sub-studies and those receiving

126 autoantibodies from the sera of 51 adult ICL patients (out of a cohort of 72).

127 ich are typically associated with studies of patient pathways using patient interviews.

128 provement (ACR20) response at week 24 in all patients per assigned treatment group.

129 d for roughly 9 million commercially insured patients per year.

130 ifferences among the studies with regards to patient population, clinical settings, and outcomes exam

131 assessments were completed on 36,261 unique patients presenting to surgical clinics across five hosp

132 Outcomes were assessed according to patients' receipt of initial assessments by a lung cance

133 One hundred forty-five patients received 197 courses of ISA prophylaxis.

134 One hundred percent and 99% of patients received the assigned intervention in the PVI-a

135 Yet, this specific subset of patients remains poorly described.

136 tive use, clinical research parsing what AUD patients remember from alcohol-related episodes is lacki

137 s for all events at every hospital where the patient reported receiving care were acquired for adjudi

138 d distance visual acuity, complications, and patient-reported outcomes measures.

139 r clinical-grade assays developed to predict patient response and, ultimately, to help select those m

140 The ability to rapidly predict SaB patient responses and guide personalized treatment regim

141 Both complications and preoperative patient risk have been shown to increase costs following

142 The patient's father, brother and one aunt were identified a

143 ented in the medical record within 7 days of patient's ICU discharge date to identify and classify ad

144 ms can be life-threatening, greatly decrease patient's quality of life, and are a substantial burden

145 We measured patient's self-care and care partner contributions to se

146 ents in 3D-printed phantoms representing the patient's vasculature.

147 mic, epigenomic and/or proteomic analysis of patient samples, and phenotypic assays in personalized c

148 ected at low rates, and cosmetic outcome and patient satisfaction with breast appearance were high wi

149 These CMR thresholds should be used for patient selection in future trials to determine if tricu

150 r, a general approach to engender endogenous patient-specific cellular therapy, without the need for

151 Patient specimens reveal a strong correlation between st

152 After controlling for patient stability, the intervention was still associated

153 ording to their PK parameter values revealed patient subgroups for each drug in which inter-patient v

154 individuals with limited mobility including patients that are hospitalized or obese.

155 l characteristics of infected critically ill patients that mediate the associated pathogenesis, inclu

156 Patients that undergo a TACE-treatment are categorised i

157 In the 12 patients, the coregistration of multimodal PET/MRI tumor

158 Compared with white patients, the IRRs were 0.70, 0.75, and 0.64 for Asians,

159 Of 197 hospitalized patients, the mean (SD) age of the cohort was 60.6 (16.2

160 ntrivial proportion of trials to assign more patients to an inferior arm, (4) difficulty of validly a

161 oinflammation by using samples from post-FMT patients to colonize GF mice shows a direct effect of fe

162 lly noninvasive tumors that recur and commit patients to long-term invasive surveillance, to aggressi

163 isk calculator might be useful for triage of patients to the limited number of intensive care unit be

164 sub-groups, with the exception of high MELD patients transplanted with "high-risk" grafts.

165 tend to a large region because two thirds of patients treated at KHCC were non-Jordanians.

166 her incidence of aspirin resistance than all patients treated with aspirin alone and TCT decreased th

167 leads to better disease-specific survival in patients treated with surgery alone.

168 istant bacterial strains further complicates patient treatment.

169 of intact, freshly excised specimens from 83 patients undergoing BCS and on dissected specimens from

170 ntestinal and blood cultures of 24 pediatric patients undergoing chemotherapy or hematopoietic stem c

171 rgoing BCS and on dissected specimens from 7 patients undergoing mastectomy.

172 tructive pulmonary disease (4% versus 7%) in patients undergoing metabolic surgery.

173 Patients underwent a 3-month post-CRT positron emission

174 During the 15-year period, 207 patients underwent LT after Y90.

175 Patients underwent prospective, protocol-based monitorin

176 OS2 deficiency was clinically silent in this patient until lethal infection with CMV.

177 tient subgroups for each drug in which inter-patient variability was largely decreased compared to th

178 ecessarily benefitting from them; a group of patients variously designated as having 'difficult to tr

179 The mean preoperative IOP for all patients was 15.2 mmHg (standard deviation [SD], 3.4 mmH

180 mean age +/- standard deviation (SD) of the patients was 28.4 +/- 5.6 years (range: 18-43).

181 set composed of 500 chest radiographs in 500 patients was evaluated by the CV19-Net and three experie

182 Short-term mortality in ICU-admitted stroke patients was high with 30 days mortality of 31% in ische

183 The increase of white blood count in 28 patients was lower after recurrent MI compared with thei

184 Patients were categorized into 4 groups (A, B, C, and D)

185 Results: Forty-eight of 72 patients were evaluable for a first response assessment

186 l articles containing of information of 3328 patients were evaluated.

187 Patients were examined at the end of each 4-month period

188 All patients were followed up over a 1-year period (study en

189 Thirty patients were found to have cysts on initial imaging.

190 Thirteen patients were identified to have RRD within 3 months of

191 216 066 patients were included.

192 These patients were less likely to present Candida growth in a

193 Patients were randomized 3:2 to suprachoroidally injecte

194 All patients were registered at the Thalassemia Comprehensiv

195 Annual mortality rates among breast cancer patients were significantly greater in LMICs in South As

196 reatment (8 mg/kg, 6x, monthly) from 12 cAMR patients who failed standard of care treatment with intr

197 We compared 16 patients who had GHPs showing neoplastic transformation

198 Ps showing neoplastic transformation with 39 patients who had non-neoplastic GHPs.

199 Patients who received pretransplant dialysis treatment i

200 erexcitable only when they were derived from patients who responded to lithium; they featured sustain

201 A total of 151 patients who underwent a major hepatic resection were ra

202 ct validity was evaluated on a sample of 120 patients who underwent laparoscopic Roux-en-Y gastric by

203 is 10-year retrospective review, consecutive patients who underwent primary vitrectomy for TRD from p

204 This was a multicenter study including 4949 patients who underwent TAVR (mean age, 81+/-8 years, mea

205 We included mechanically ventilated ICU patients who were given moderate-to-high doses of opioid

206 even when they had been exposed to an index patient with multidrug-resistant tuberculosis.

207 First- or second-degree blood relatives of a patient with ovarian cancer with a known germline pathog

208 , small sample size, and examination of only patients with 1-year outcome data.

209 s were driven by TCR clusters shared between patients with a characteristic trajectory of clonotypes

210 The secondary group consisted of patients with a history of brain radiation therapy or cr

211 All records from patients with a minimum of 6 months of follow-up and at

212 wo cycles of blinatumomab; the percentage of patients with a molecular response increased further aft

213 Excluding patients with a need or likely need for laser or surgery

214 Methods: Ten patients with a peripheral AVM (mean age, 40 y; 4 men an

215 Methods: Five patients with a prior diagnosis of breast cancer, renal

216 in dorsal ACC (p = .03), and the subgroup of patients with a schizophrenia diagnosis had higher gluta

217 A-A2) that has been observed in about 35% of patients with acute myeloid leukaemia (AML).

218 sed in clinical practice, particularly among patients with alcohol-associated or NASH-related cirrhos

219 isk of cardiovascular death was observed for patients with and without postoperative AF (incidence ra

220 Patients with anemia and lower-risk myelodysplastic synd

221 rquartile range {IQR} 0-1] vs 1 [IQR 0-2] in patients with any positive BDG test; P = .039).

222 n diastolic dysfunction (DD) and outcomes in patients with aortic stenosis undergoing transcatheter a

223 ther such Crs-based phenotypes existed among patients with ARDS before the COVID-19 pandemic and to c

224 ethods: We undertook a secondary analysis of patients with ARDS, who were invasively ventilated on co

225 Patients with bilateral infiltrates more often had a pri

226 esponse syndrome (SIRS) frequently occurs in patients with cardiogenic shock and may aggravate shock

227 in practice to assess endoscopic activity in patients with CD.

228 udy differences between healthy controls and patients with celiac disease (CD).

229 Methods: Forty-three patients with cerebral gliomas (9 low-grade, 34 high-gra

230 hepatocellular carcinomas (HCCs) develop in patients with chronic hepatitis, which creates a microen

231 dietary sodium restriction in reducing BP in patients with CKD stage G3 or G4 and hypertension, we co

232 ) has been observed to improve the health of patients with coronary artery disease (CAD).

233 ected from seven clinical areas, occupied by patients with COVID-19, and a public area of the hospita

234 hibitors or angiotensin receptor blockers in patients with COVID-19.

235 regulation in postmortem cortical samples of patients with depression.

236 ual information on emotional attributions in patients with depression.

237 FA (UWFA) and more challenging situations in patients with developmental delay.

238 preclinical models of diabetes mellitus and patients with diabetes mellitus facilitating the bi-dire

239 comparison made between normal patients and patients with dissection, right CCA (p = 0.000), ICA (p

240 sed risk of acute cerebrovascular disease in patients with dual infection merits further investigatio

241 erived glycation free adducts were higher in patients with early decline in GFR, compared to those wi

242 among 84,479 unique subjects with IHD (2,103 patients with FH) on the basis of 28 studies, 6.7% (95%

243 16 unique subjects with premature IHD (1,471 patients with FH) on the basis of 32 studies, and 7.2% (

244 e subjects in the general population (33,036 patients with FH) on the basis of 44 studies, 3.2% (95%

245 bjects with severe hypercholesterolemia (920 patients with FH) on the basis of 7 studies.

246 Using data from patients with focal brain damage, we demonstrate that th

247 fferences in cognition and behaviour between patients with FTD-ALS and bvFTD alone.

248 safety, and tolerability of berotralstat in patients with HAE over a 24-week treatment period (the p

249 howed encouraging efficacy as monotherapy in patients with heavily pretreated multiple myeloma in the

250 tedanib might provide therapeutic benefit in patients with HHT.

251 retrospective arm of this study included 146 patients with histologically confirmed stage IIIB-IV NSC

252 All patients with histologically verified primary or seconda

253 efects in cardiomyopathy-associated genes in patients with HLHS, which may portend impaired functiona

254 One hundred eighty-three patients with hypertrophic cardiomyopathy and a low- or

255 neral population cohort to as high as 78% in patients with inflammatory bowel disease(2).

256 ) cells was identified in lung and uterus of patients with LAM, sharing close transcriptomic identity

257 Information about where patients with limited health insurance receive maintenan

258 Twenty-seven patients with low CrAg titers were treated with antifung

259 nd of matched metastatic tumor biopsies from patients with metastatic prostate adenocarcinoma and CRP

260 -CoV-2-specific T cells in 10 of 10 COVID-19 patients with mild symptoms.

261 urrent understanding derived from studies of patients with MS and animal models of how specific cytok

262 n associated with regular IVT injections for patients with nAMD.

263 In patients with negative [TIMP-2]*[IGFBP7] at baseline, th

264 Patients with nonischemic HF were randomized to routine

265 rsus placebo and narrowband-ultraviolet B in patients with nonsegmental vitiligo.

266 Patients with opioid use disorder (OUD) who are hospital

267 Improvements in the outcomes of patients with pancreatic ductal adenocarcinoma (PDAC) ha

268 lly, the age at onset of Parkinson's disease patients with pathogenic/likely pathogenic variants in A

269 nitive performance over 1, 2, and 4 years in patients with PD.

270 Patients with PEX achieved a lower maximal workload (PEX

271 t been validated in a well-defined cohort of patients with PG.

272 nge studies may also aid decision-making for patients with PH-LHD or otherwise unexplained dyspnea.

273 ve medications is recommended for some older patients with polypharmacy and multimorbidity when the b

274 Patients with postthrombotic femoral veins and those who

275 ssel densities were significantly reduced in patients with PXG compared with patients with PXS and no

276 y reduced in patients with PXG compared with patients with PXS and normal control subjects (all P < .

277 survival was significantly different between patients with R0 versus R1 margins but wider resection m

278 n (DBS) is an effective treatment option for patients with refractory obsessive-compulsive disorder (

279 Overall survival in patients with relapsed disease remains poor, and thus no

280 educed the risk of relapse versus placebo in patients with resected, BRAF(V600)-mutant, stage III mel

281 Pseudophakic patients with RRD managed with PPV or PPV-SB were analyz

282 Eighty-two Dutch patients with SCA3/MJD were evaluated annually for 15 ye

283 Adult patients with scaphoid waist fractures displaced by 2 mm

284 ution in order to create a cohort of virtual patients with some specific characteristics, resembling

285 ime is a newly available process measure for patients with ST-segment-elevation myocardial infarction

286 esigned to detect improvement in outcomes of patients with stage II to IV DAWT compared with historic

287 predisposition to cancer is warranted in UM patients with strong personal or family history of cance

288 BEST PRACTICE ADVICE 6: Patients with suspected celiac disease who are seronegat

289 Second, among 1,460 patients with suspected sepsis (sepsis-2 definition), BC

290 Patients with the neurological syndrome known as body in

291 er risk for transplant failure compared with patients with the same duration of pretransplant dialysi

292 ively target endocan-EGFR regulatory axis in patients with TKI-resistant NSCLC.

293 therapy with a manageable safety profile in patients with treatment-naive, or relapse or refractory

294 alization for HF and cardiovascular death in patients with type 2 diabetes mellitus.

295 For patients with ulcerative colitis, Eubacterium rectale an

296 dative neovascular AMD in the fellow eyes of patients with unilateral exudative AMD ranged from 6.25%

297 during R-CHOP-14 does not improve outcome in patients with untreated DLBCL.

298 , a novel highly selective BTK inhibitor, in patients with WM.

299 or an outcome and is applied to disaggregate patients within RCTs to define risk-based variation in b

300 roke or TIA: 2.32 versus 0.75 events per 100 patient-years (hazard ratio [HR], 3.05 [95% CI, 1.65 to