ライフサイエンスコーパス: pediatric

1 al symptoms are a common clinical problem in pediatrics.

2 Reductions in driving pressure (pediatric: 12%, adult: 2%), mechanical power (pediatric:

3 ediatric: 12%, adult: 2%), mechanical power (pediatric: 24%, adult: 46%), and modified mechanical pow

4 adult: 46%), and modified mechanical power (pediatric: 44%, adult: 46%) were achievable even when no

5 and gene expression are commonly altered in pediatric acute lymphoblastic leukemia (PALL).

6 ilar to the empirically derived treatment of pediatric acute lymphocytic leukemia, can consistently a

7 the validation cohort, models for intubated pediatric acute respiratory distress syndrome (including

8 ist to guide early adjunctive therapy use in pediatric acute respiratory distress syndrome (PARDS).Ob

9 and determined whether patients met complete pediatric acute respiratory distress syndrome criteria v

10 ially higher than previously recognized, and pediatric acute respiratory distress syndrome developmen

11 The 2015 definition for pediatric acute respiratory distress syndrome did not re

12 Incidence and mortality associated with pediatric acute respiratory distress syndrome following

13 d fluid balance, and PaO2/FIO2 6 hours after pediatric acute respiratory distress syndrome onset.

14 health records to identify patients meeting pediatric acute respiratory distress syndrome oxygenatio

15 Children meeting pediatric acute respiratory distress syndrome oxygenatio

16 xternally validated in a cohort of intubated pediatric acute respiratory distress syndrome patients f

17 (RSV) is the leading global cause of severe pediatric acute respiratory tract illness, and a vaccine

18 but global transcriptomic profiling in early pediatric AD is lacking.

19 e of patients with cleared versus persistent pediatric AD, might define age-specific changes that pre

20 Of the 19,113 pediatric admissions with sepsis (6,300 [33%] previously

21 lopinavir/ritonavir (International Maternal Pediatric Adolescent Acquired Immunodeficiency Syndrome

22 s still predominantly seen among the younger pediatric age group and current interventions targeted f

23 splant Recipients kidney offer data for 3642 pediatric (age <18 years) kidney-only transplant candida

24 The majority of pediatric ALCLs are associated with the t(2;5)(p23;q35)

25 ics (PKPD) of ciprofloxacin prophylaxis in a pediatric ALL population.

26 Four pediatric and 9 adult patients were infused with a singl

27 ch requires involvement of patients and both pediatric and adult care providers.

28 sure or mechanical power consistently across pediatric and adult datasets.

29 ofiles of canine gliomas with those of human pediatric and adult gliomas to characterize evolutionari

30 Although both pediatric and adult patients with anxiety disorders exhi

31 CDI) have increased dramatically in both the pediatric and adult populations.

32 fective as AADI placed with a patch graft in pediatric and adult refractory glaucomas.

33 In pediatric and congenital heart disease patients with sym

34 s a novel analyte for active TB detection in pediatric and extrapulmonary disease.

35 ctivity in certain subspecialties, including pediatrics and nuclear medicine.

36 establishment (i.e., an association between pediatric anxiety and a specific neurocognitive process)

37 The pathophysiology of pediatric anxiety appears to involve greater capture of

38 existing models of information processing in pediatric anxiety disorders and highlight the particular

39 n-specific cognitive training treatments for pediatric anxiety disorders rely on accurate and reliabl

40 oimaging literature on Pavlovian learning in pediatric anxiety disorders.

41 ral and brain-based targets for treatment of pediatric anxiety disorders.

42 on) to provide more robust classification of pediatric anxiety problems.

43 enges in identifying and predicting risk for pediatric anxiety.

44 cated appendicitis using data from the NSQIP-Pediatric Appendectomy Pilot Collaborative.

45 one has the potential to treat uncomplicated pediatric appendicitis with fewer disability days than s

46 vasopressin (AVP) is significantly lower in pediatric ASD cases vs. controls.

47 s support additional studies, given the high pediatric asthma burden and widespread exposure to BPA i

48 magnetic resonance imaging ((129)Xe MRI) in pediatric asthma is poised to advance our understanding

49 /FM could be useful for long-term control of pediatric asthma.

50 ted frequency in patients that suffer from a pediatric autoinflammatory disease, chronic recurrent mu

51 s, Plk1 is a potential therapeutic target in pediatric B-ALL and selective targeting of Plk1 can be a

52 blood and bone marrow mononuclear cells from pediatric B-ALL patients, cultured ex vivo, with Plk1-ta

53 The Adult Basic and Advanced Life Support, Pediatric Basic and Advanced Life Support, Neonatal Life

54 ter, retrospective, cross-sectional study of pediatric BAV patients followed since 2004 was performed

55 ular samples included bacterial culturing of pediatric blood culture bottles; 16SrDNA amplification a

56 toid rhabdoid tumors (ATRTs) are challenging pediatric brain cancers that are predominantly associate

57 Since 2010, 60 postmortem pediatric brain tumor donations from 26 institutions wer

58 or fossa type A (PFA) ependymoma is a lethal pediatric brain tumor proposed to be driven solely by ep

59 that posterior fossa A ependymoma, a lethal pediatric brain tumor with a silent genome, is dependent

60 PET imaging probe for this common malignant pediatric brain tumor.

61 rospectively examined the immune profiles of pediatric brain tumors after immunotherapy.

62 ucture is feasible in long-term survivors of pediatric brain tumors and that metformin is safe to use

63 th cranial radiotherapy for the treatment of pediatric brain tumors by reducing the dose to normal ti

64 n made in developing PET imaging methods for pediatric brain tumors.

65 Keywords: Adults and Pediatrics, Brain/Brain Stem, CNS, Computer Aided Diagno

66 antibacterial prophylaxis administration in pediatric cancer and HSCT patients.

67 ounds were potent cytotoxins toward numerous pediatric cancer cell lines and were minimally toxic to

68 The Oncode Institute, Pediatric Cancer Foundation Rotterdam, Dutch Cancer Soci

69 a therapeutic challenge in neuroblastoma, a pediatric cancer in which MYCN amplification is strongly

70 Pineoblastoma is a rare pediatric cancer induced by germline mutations in the tu

71 : This work was supported by the Luke's Army Pediatric Cancer Research Fund St.

72 dult normal tissue, adult cancer tissue, and pediatric cancer tissue.

73 Improvements in pediatric cancer treatment that include the alleviation

74 Given the importance of this pathway in pediatric cancer, it is imperative that future studies s

75 ources of somatic variation across adult and pediatric cancers and are some of the most clinically-ef

76 coma and malignant rhabdoid tumor (MRT), two pediatric cancers that are sensitive to other p53-depend

77 Different pediatric cancers with a high risk of relapse share a co

78 pediatric donor organs would be allocated to pediatric candidates, compared to only 46% in donor serv

79 Studies of pediatric cardiac arrest use inconsistent outcomes, incl

80 ave not been translated to clinical care for pediatric cardiac arrest, in part because signal noise c

81 is, to the best of our knowledge, the first pediatric case of PLA caused by A. defectiva.

82 One pediatric case, with picornavirus and influenza A coinfe

83 ation was compared between younger and older pediatric cases and between children and adults.

84 Few pediatric cases of coronavirus disease 2019 (COVID-19) h

85 virus type 1 (HIV-1) continues to cause new pediatric cases of infection through breastfeeding, a se

86 Pediatric cases were aged <18 years; congenital and peri

87 The intervention used was pediatric cataract surgery with IOL implantation, and th

88 o further characterize prognostic factors in pediatric CD and to evaluate the impact of treatment alg

89 onset were more likely to have poor outcome (Pediatric Cerebral Performance Category score > 1, incid

90 3 patients with sickle cell anemia and known pediatric cerebrovascular outcomes.

91 ole genome sequencing on isolates from early pediatric CF pulmonary infections and from comparator gr

92 tty liver disease (NAFLD) is the most common pediatric chronic liver disease.

93 r review summarizes the current knowledge of pediatric clinical disease, role in transmission, risks

94 nd conducted validation studies to develop a pediatric CMT-specific QOL outcome measure (pCMT-QOL).

95 ere, we describe the TIME of >6000 primarily pediatric CNS tumors using a deconvolution approach (met

96 The pediatric cohort comprised 452 individuals from 411 fami

97 sure in a predominantly low-income, minority pediatric cohort is associated with asthma morbidity and

98 In this large pediatric cohort of patients with BAV, valve morphology,

99 =16 years) with KC and 31 eyes of 31 healthy pediatric controls.

100 d with COVID-19, compared with typical acute pediatric COVID-19 infection, with an emphasis on thorac

101 -recommended core outcome set is lacking for pediatric critical care outcomes.

102 espread adoption of rapid genomic testing in pediatric critical care requires robust clinical and lab

103 Manuscripts evaluating outcomes after pediatric critical illness.

104 (EEN) can induce remission in patients with pediatric Crohn's disease (CD).

105 Lastly, we compare scRNA-seq profiles from pediatric Crohn's disease epithelium alongside matched h

106 Pediatric Crohn's disease is characterized by a higher i

107 l evidence reviews identified the paucity of pediatric data and the need for more research involving

108 hospitalized patients are inappropriate, but pediatric data are limited.

109 ational Surgical Quality Improvement Program-Pediatric database (2012-2016) who underwent a high (>=1

110 atin-modifying enzymes are a common cause of pediatric developmental disorders.

111 Subsequently, a severe and novel pediatric disorder termed multisystem inflammatory syndr

112 C(12) fatty acids, are used to treat several pediatric disorders and are widely consumed as a nutriti

113 With AC allocation, 77% of pediatric donor organs would be allocated to pediatric c

114 livers were split: 54% from adult, 46% from pediatric donors.

115 giectasia in transplanted kidneys, both from pediatric donors.

116 ubjects aged 2 to 26 years from the national Pediatric Eczema Elective Registry (PEER) cohort.

117 A pediatric end -stage liver disease score >=40, postopera

118 ytokine signatures characterizing individual pediatric endotypes might require age-specific therapies

119 sion and activity of KPNA7 in a rare type of pediatric epilepsy.

120 investigating the safety of early feeding in pediatric GI surgery, with or without a fast-track progr

121 been the traditional model of care following pediatric GI surgery.

122 Schlemm's canalization in different forms of pediatric glaucoma is under-reported.

123 Patients with pediatric glaucomas seen at the University of Minnesota

124 rowth and proliferation of primary adult and pediatric glioma cells, but not the viability of normal

125 A high percentage of pediatric gliomas and bone tumors reportedly harbor miss

126 , and based on their expression in adult and pediatric gliomas, nine of these hits are prioritized as

127 rticle describes the key imaging findings in pediatric groin injuries, placing special emphasis on th

128 ed with antibiotic utilization data from the Pediatric Health Information System database from Januar

129 the routine use of hemodynamic assessment in pediatric heart transplant (HT) patients, expected intra

130 d with coronary artery vasculopathy (CAV) in pediatric heart transplant (HT) recipients.

131 25), malignant rhabdoid tumors (n = 229) and pediatric high-grade gliomas (n = 401), we show signific

132 YPHIVs aged >=18 years in the Pediatric HIV/AIDS Cohort Study (PHACS) AMP Up cohort ap

133 e outpatient department of a nongovernmental pediatric hospital in Siem Reap.

134 oma between 1989 and 2017 at a tertiary care pediatric hospital were analyzed.

135 imary or postsecondary DENV infection from a pediatric hospital-based study in Nicaragua using a Mult

136 Compared to all-cause pediatric hospitalizations, severe sepsis hospitalizatio

137 Using the experience of two tertiary pediatric hospitals with six sets of craniopagus twins,

138 We conducted a retrospective chart review of pediatric HT recipients who had undergone HT between Jan

139 ure CAV than rejection on protocol biopsy in pediatric HT recipients.

140 incorporates risk factors that are unique to pediatric hypertrophic cardiomyopathy.

141 sfer of the medical care of individuals with pediatric IEIs to adult facilities is also a complex tas

142 Pediatric immunity is distinct from that of adults, whic

143 Of significant relevance to pediatrics, in utero and perinatal stressors may alter t

144 Pediatric index patients with community-associated methi

145 Sixteen pediatric Indian tuberculosis cases were age- and sex-ma

146 unique features of reservoir composition in pediatric infection that should be considered for eradic

147 ildren admitted to United Kingdom PICUs with pediatric inflammatory multisystem syndrome temporally a

148 Pediatric KC cases <18 years of age were evaluated at a

149 chanical and aberrometric characteristics in pediatric keratoconus (KC).

150 D8 T cells were measured in 32 of 36 viremic pediatric kidney recipients using intracellular cytokine

151 Pediatric kidney transplant outcomes associated with exp

152 uently used as a reason for organ refusal in pediatric kidney transplantation.

153 En bloc transplantation of small pediatric kidneys in children is associated with superio

154 Pediatric large B-cell lymphomas (LBCLs) share morpholog

155 um of hematologic malignancies, particularly pediatric leukemias with poor patient outcomes.

156 Biliary atresia (BA) is a severe pediatric liver disease resulting in necroinflammatory o

157 Extrahepatic biliary atresia (BA) is a pediatric liver disease with no approved medical therapy

158 lopmental exposure to PFAS can contribute to pediatric liver injury.

159 ere associated with allograft dysfunction in pediatric liver transplant recipients.

160 measure of adherence to immunosuppression in pediatric liver transplant recipients.

161 crease pediatric transplant rates and reduce pediatric liver transplant waitlist mortality.

162 reased from 2% in 2002 to 15% in 2017, while pediatric liver transplants from DO donors only increase

163 ll cohort included immunocompromised status, Pediatric Logistic Organ Dysfunction 2 score, day 0 vaso

164 dian (Q1-Q3) Pediatric Risk of Mortality and Pediatric Logistic Organ Dysfunction scores at PICU admi

165 is (odds ratio [95% CI]), summation of daily Pediatric Logistic Organ Dysfunction scores, 1.01/per po

166 ally and molecularly characterized cohort of pediatric low-grade gliomas (pLGGs) published to date.

167 lid candidates for antitumor drug design for pediatric malignancies driven by the MYC oncogene.

168 athway alterations across a diverse group of pediatric malignancies.

169 ing critical care medicine, palliative care, pediatric medicine, nursing, social work, gerontology, g

170 aring advantage with PRT in the treatment of pediatric medulloblastoma.

171 view of the clinical and imaging findings of pediatric MIS-C associated with COVID-19, compared with

172 ds, the dominant source of FA in adults, the pediatric model also included gastrointestinal symptoms

173 d areas for future research that can use the pediatric model of disease, transmission, and immunity t

174 Thus, it is important to utilize pediatric models to inform cure-directed approaches for

175 followed at 12 clinics in the US Network of Pediatric MS Centers, who received initial therapy with

176 Initial treatment of pediatric MS/CIS with newer DMTs led to better disease a

177 ve cohort study using clinical data from the Pediatric National Surgical Quality Improvement Program

178 tained from the American College of Surgeons Pediatric National Surgical Quality Improvement Program

179 The Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group, consisti

180 Within the Pacific Pediatric Neuro-Oncology Consortium, we assessed the saf

181 The Response Assessment in Pediatric Neuro-Oncology working group, consisting of an

182 Approximately half of sporadic pediatric norovirus AGE cases were caused by GII.4 norov

183 ovide important information on which strains pediatric norovirus vaccines should protect against.

184 ings suggest a neurobiological mechanism for pediatric obesity consistent with rodent work showing th

185 task-positive and task-negative networks in pediatric OCD may contribute to the impaired control ove

186 oides difficile infection, and azithromycin (pediatrics only) expand the role SAARs can play in ASP e

187 c HPDL variants as a cause of a progressive, pediatric-onset spastic movement disorder with variable

188 18 years of age) in the practice of a single pediatric ophthalmologist were eligible.

189 signatures could not be detected in either a pediatric or a second adult IBD cohort.

190 Baseline Pediatric Overall Performance Category was normal in 38%

191 Pediatric palliative care aims to alleviate suffering an

192 advancements in the specific domains within pediatric palliative oncology care including family-cent

193 The field of pediatric palliative oncology-encompassing primary palli

194 ring islet isolation of younger and fibrotic pediatric pancreases, gave increased islet yield with im

195 ational Surgical Quality Improvement Program Pediatric Participant Use Data File from 2013 to 2017.

196 possible to achieve low-motion fMRI data in pediatric participants (age range: 7-17 years old) under

197 (DWI) was accurate in detecting arthritis in pediatric participants with juvenile idiopathic arthriti

198 rebral arteriopathy and ischemic stroke in a pediatric patient with coronavirus disease 2019 who pres

199 tive value for the detection of PTLD in a 28-pediatric-patient cohort with a clinical suspicion of th

200 Pediatric patients (< 18 yr old) with a severe isolated

201 mapping data were collected from 48 healthy pediatric patients (14 years +/- 3 [standard deviation];

202 No difference was found in pediatric patients (23 of 67) compared with adults or sp

203 icante, Spain) study comprised 49 eyes of 49 pediatric patients (age <=16 years) with KC and 31 eyes

204 study by using data from CT examinations of pediatric patients (February to December 2018).

205 junal mucosal grafts using biomaterials from pediatric patients and show that patient-derived organoi

206 Pediatric patients are excluded from most coronavirus di

207 age hypertrophic cardiomyopathy in adult and pediatric patients as well as supporting documentation t

208 solated in an acute phase from DENV-infected pediatric patients correlates with severe disease develo

209 retinal gene replacement therapy delivery in pediatric patients exists.

210 Identifying sepsis in pediatric patients is difficult and can lead to treatmen

211 om gastrointestinal and blood cultures of 24 pediatric patients undergoing chemotherapy or hematopoie

212 e and travel destination, 1435 (83%) of 1722 pediatric patients were vaccine-eligible; only 68 (5%) o

213 We report a series of febrile pediatric patients with acute heart failure potentially

214 opoietic stem cell transplantation (HSCT) in pediatric patients with acute lymphoblastic leukemia (AL

215 ol fumarate hydrate (FP/FM) was evaluated in pediatric patients with bronchial asthma.

216 mic antifungal prophylaxis administration in pediatric patients with cancer and HSCT recipients.

217 otic use in febrile, nonseverely neutropenic pediatric patients with cancer.

218 Seventy-seven pediatric patients with clinically confirmed fish allerg

219 Among pediatric patients with EoE, diagnosis most commonly occ

220 Six pediatric patients with glioma tolerated this combinatio

221 Colon from 2 pediatric patients with Hirschsprung disease was used to

222 Here, we studied pediatric patients with IBD and IBD + CDI, comparing lon

223 evalence of monogenic disease in a cohort of pediatric patients with IBD.

224 tion assay using adult patients and stool of pediatric patients with inflammatory bowel disease and i

225 th offering intestinal transplantation in US pediatric patients with short bowel syndrome.

226 mended in the following patient populations: pediatric patients, healthy nonpregnant women, older pat

227 For pediatric patients, routine inclusion of an anaerobic bl

228 I symptom presentations in a large cohort of pediatric patients.

229 t bloodstream infection in immunocompromised pediatric patients.

230 ong-term clinical benefits remain unclear in pediatric patients.

231 terminants for ascending aorta dilatation in pediatric patients.

232 used to slow tumor growth in both adult and pediatric patients.

233 th DHF/Severe dengue disease in hospitalized pediatric patients.

234 While there are many causes of pediatric pharyngitis, group A streptococcal pharyngitis

235 ion lymphoproliferative disorder (PTLD) in a pediatric population and explore its feasibility during

236 scotopic pupillary size and function in the pediatric population in a clinical setting.

237 in mucosal membranes", "pressure injuries in pediatric population", "pressure injury at end of life",

238 egic autorefraction is appropriate to use in pediatric population-based studies.

239 ne x Sex effects of ADCYAP1R1 in a high-risk pediatric population.

240 We excluded animal studies and trials in pediatric populations (age < 16 years old), pregnant wom

241 acquired pressure ulcers occur frequently in pediatric populations, prolonging their hospitalization

242 rn about disease-modifying host factors from pediatric populations.

243 of all literature relating to SARS-CoV-2 in pediatric populations.

244 with early-onset AD, but are not feasible in pediatric populations.

245 care settings, the public health sector, and pediatric populations.

246 cess to younger ages through the forthcoming pediatric praziquantel formulation and improving treatme

247 a priori defined as a respiratory PedsQL, a pediatric quality of life measure, greater than or equal

248 an optimization schema for the practices of pediatric radiology and nuclear medicine.

249 The use of pediatric regimens is likely to lead to more adult patie

250 is not significantly associated with DGF in pediatric renal transplant recipients.

251 wards in 56 US and Canadian hospitals in the Pediatric Research in Inpatient Settings Network from De

252 crossover trial comparing two schedules for pediatric resident physicians during their intensive car

253 Median (Q1-Q3) Pediatric Risk of Mortality and Pediatric Logistic Organ

254 elayed fractional dose regimens of adult and pediatric RTS,S/AS01 formulations.

255 Irritability in pediatric samples is associated with higher rates of sub

256 hness, alpha-diversity, or structure between pediatric samples types; however, these were all highly

257 changes that might help distinguish between pediatric sepsis and infection-negative systemic inflamm

258 Accordingly, the Life After Pediatric Sepsis Evaluation investigation was conducted

259 In-hospital pediatric sepsis mortality has decreased substantially,

260 The Improving Pediatric Sepsis Outcomes Sepsis definitions demonstrate

261 Among Improving Pediatric Sepsis Outcomes Sepsis patients, 60.8% were ad

262 Improving Pediatric Sepsis Outcomes Sepsis was defined by electron

263 rapy is associated with improved outcomes in pediatric sepsis, but minimal data exist to guide empiri

264 ders known as the RASopathies, and now large pediatric sequencing studies have identified frequent so

265 still a matter of debate, particularly in a pediatric setting.

266 Among 18,210 pediatric severe sepsis hospitalizations, 1,024 (5.6%) u

267 iferative disorder (PTLD) is reported in the pediatric small bowel transplant (SBTx) population, whic

268 Rhabdomyosarcoma (RMS) is the most prevalent pediatric soft-tissue sarcoma.

269 Neuroblastoma is a deadly pediatric solid tumor with infrequent recurrent somatic

270 omerase I inhibitors used to treat high-risk pediatric solid tumors, but they often show poor efficac

271 incidence and risk factors of obesity among pediatric solid-organ transplant recipients (heart, lung

272 taria; Fondo Europeo de Desarrollo Regional; Pediatrics Spanish Society; Departament de Salut, Genera

273 December 2012 and June 2016, there were 755 pediatric sporadic norovirus cases and 45 reported outbr

274 Thirty-four adult and 5 pediatric studies (3377 patients) from Asia, Europe, and

275 quantify latent reservoirs, particularly in pediatric studies where sample availability is limited.

276 on sequencing has identified three unrelated pediatric subjects, each with a clinical diagnosis of Le

277 iority targets for prevention efforts within pediatric surgery.

278 f revisit-associated resource utilization in pediatric surgery.

279 insic functional connectivity manifests with pediatric symptoms of anxiety, irritability, and attenti

280 re we expanded RASGRP1 expression surveys in pediatric T-ALL and generated a RoLoRiG mouse model cros

281 samples correlate with inferior outcomes for pediatric T-ALL patients.

282 a on profiling the inflammatory responses in pediatric TB are available.

283 l'Hopital Gabriel Toure, the main source of pediatric tertiary care in Bamako, Mali.

284 sources published by the American Academy of Pediatrics, the Society of Critical Care Medicine, the A

285 roaching or having completed transition from pediatric to adult healthcare were included.

286 As a result, PELD-Na-Cr could increase pediatric transplant rates and reduce pediatric liver tr

287 DL-BAAM]) was trained on 15 129 frontal view pediatric trauma hand radiographs obtained between Decem

288 s whose population of interest was neonatal, pediatric, trauma, or noncritically ill.

289 roximately 95% of currently vaccine-eligible pediatric travelers were unvaccinated, and antimicrobial

290 Among 1992 pediatric typhoid fever patients, 1616 (81%) had travele

291 ute severe colitis (ASC), chronically active pediatric UC, cancer and mortality.

292 fy evidence-based predictors for outcomes in pediatric UC, which may be used to optimize treatment al

293 were determined by surveying 202 experts in pediatric UC.

294 We compared 103 pediatrics under 15 yeas old (age, 10.8+/-2.6 years; mal

295 imulator Sickness Questionnaire modified for pediatric use (Peds SSQ).

296 aki disease (KD) display overlap with common pediatric viral illnesses, leading some to hypothesize t

297 ility to study outcomes of rare subgroups of pediatric VTE (eg, renal vein thrombosis), and will be i

298 ical trials of direct oral anticoagulants in pediatric VTE are ongoing, with results anticipated soon

299 Pediatric VTE encompasses a highly heterogenous populati

300 enter cross-sectional study was performed in pediatric wards in 56 US and Canadian hospitals in the P