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1 rvoir into which antiretroviral drugs poorly penetrate.
2 forces, and migration velocities have yet to penetrate.
5 ysine residue that serves as a "stinger" and penetrates a triad of carboxyl groups in the S3-S4 linke
6 affics to the endoplasmic reticulum (ER) and penetrates a virus-induced structure in the ER membrane
8 ed into both flanks of L6, has enhanced cell-penetrating ability in human bronchoalveolar carcinoma A
9 todynamic therapy (PDT) by the use of highly penetrating acoustic waves to activate a class of sound-
10 d and applied in vivo topically to mice eyes penetrated across all cornea layers and resulted in a si
12 erminant of the ability of a cationic AMP to penetrate and disrupt the bacterial plasma membrane, the
13 on surface-active manatees, and at minimum, penetrate and probe manatee epidermis with their mouthpa
15 ically, capsids with ablated SIA binding can penetrate and transduce the CNS with low to moderate eff
16 x, translocated into the nuclei of initially penetrated and surrounding cells, and reprogram the expr
17 resent a facile method of enhancing the cell penetrating and antibacterial properties of cationic amp
18 has very low bandwidth it is very reliable, penetrating and difficult to jam which makes it a great
19 compounds upon mucosal administration, mucus-penetrating and mucoadhesive particles have been designe
20 th lumbar DRG (L6-L7) were instrumented with penetrating and non-penetrating electrode arrays to reco
21 n agents, including latency reversal agents, penetrate, and function in diverse anatomical sites harb
25 lary sphincter at the transition between the penetrating arteriole and first order capillary, linking
31 robial peptides unusual for their ability to penetrate bacterial membranes and kill cells without cau
32 OR 0.31 (95% CI, 0.15-0.66); P = 0.002), and penetrating behavior [OR = 00.36 (95% CI, 0.16-0.81); P
33 lysis indicated that UV-B radiation does not penetrate below the skin, suggesting a possible signalli
34 r improved polyplex targeting materials that penetrate brain extracellular matrix to increase transfe
35 lyethylene glycol (PEG) coatings efficiently penetrate brain tumor tissue as well as healthy brain pa
36 odify outdoor pollution particles after they penetrate buildings, where the majority of exposure occu
39 resolution, suggests an alternative membrane-penetrating cation-dependent mechanism in its N-terminal
41 showed that the designed alkyl CPs strongly penetrate cell membranes, binding to KRAS and NRAS mRNAs
42 bound CyaA(1-710)/HlyA(411-1024) chimera to penetrate cells and deliver the AC enzyme into their cyt
43 us sabdariffa (of the Malvaceae family) that penetrates cells and inhibits their proteasomal activiti
45 vigate through the host endomembrane system, penetrate cellular membranes, and undergo capsid disasse
46 el demonstrated the effectiveness of the BBB-penetrating combination therapy and the macrophage-media
48 that other types of ocular injuries, such as penetrating corneal trauma and ocular hypertension also
50 exhaust with diameters less than 100 nm may penetrate deep into the human respiratory system and cau
53 Compared with uninjured glands, H pylori penetrated deep within SPEM glands, in situ, through int
54 While light induces enhanced mobility that penetrates deep into the surface, resulting in lower den
56 maller tip cross-sectional geometries should penetrate deeper into a target than projectiles with lar
57 phthalates, dimethyl and diethyl phthalates, penetrate deeper into skin with similar exposure compare
58 egies employ a strong multiphoton laser that penetrates deeply into the tissues of living, anesthetiz
59 that nearly 4% of existing groundwater wells penetrate defined bases of fresh water, and nearly 16% o
60 emale gametophyte, growing pollen tubes must penetrate different tissues within the pistil, the femal
61 = 0.60 (95% CI, 0.41-0.88); P = 0.009], and penetrating disease behavior [OR = 0.58 (95% CI, 0.39-0.
62 f postoperative smoking, CD prophylaxis, and penetrating disease behavior could be independent predic
65 rimary afferents in the lumbar DRG using non-penetrating electrode arrays and to characterize the rel
66 ) were instrumented with penetrating and non-penetrating electrode arrays to record neural activity d
68 Modification of the inhibitor with a cell-penetrating entity yielded a cell-permeable proteomimeti
69 due to their bioreactivity, their ability to penetrate every organ, including the brain, and their ab
71 ratively, based on the observation that they penetrate farther into membranes as the C2AB tandem than
77 , and/or active dosimetry; however, the ever penetrating GCR will continue to pose the most significa
79 d ticks (Ixodidae) enable these parasites to penetrate host skin, secrete saliva, embed, and suck blo
80 l nucleic acids [L-SNAs]), which are able to penetrate human skin to knock down cutaneous gene target
82 etrated porcine cornea by 60 min and 0.0002% penetrated human cornea and 0.001% penetrated human scle
85 +); however, the C2B domain will bind to and penetrate in trans to a membrane containing phosphatidyl
86 s analog to the magnetic field in metals and penetrates in the frustrated phase as an array of underc
87 composed of hygroscopic polypyrrole chloride penetrating in hydrophilicity-switchable polymeric netwo
93 ase reactivity in the blood plasma, possibly penetrating intact into membranes and significantly help
94 ed capability of CD8(+) cytotoxic T cells to penetrate into a large target, T. gondii cysts, for thei
95 from N. tabacum display a greater ability to penetrate into a stiffer matrix compared with pollen tub
96 e to the ability of accelerated electrons to penetrate into a substance, ELT provides the decompositi
97 can reach the brain after venous injection, penetrate into GBM cells via endocytosis, dissociate to
98 r permeability than GS-AuNPs and can rapidly penetrate into submandibular salivary glands, be efficie
100 stalline film allows gas molecules to easily penetrate into the channel region, thereby improving the
102 were unable to fuse with the egg membrane or penetrate into the ooplasm, and fertilization could only
103 ystems (DDSs), which enable drugs to rapidly penetrate into the tumor cores with no need of long bloo
108 harmacokinetic analyses revealed that INT131 penetrates into the brain with a brain to blood partitio
109 uterine luminal epithelium and subsequently penetrates into the underlying stroma to firmly embed in
111 rmanent posterior teeth demonstrating caries penetrating into inner enamel or outer dentin were inclu
117 intraoperative perforation and conversion to penetrating keratoplasty (PK) and the percentage of pati
122 including endothelial keratoplasty (EK) and penetrating keratoplasty (PK); amphotericin B, voriconaz
126 ears of age or younger who underwent primary penetrating keratoplasty at Department of Ophthalmology,
128 ents, selective keratoplasties have replaced penetrating keratoplasty to treat corneal decompensation
129 : 13.5% required tarsorrhaphy, 5.8% required penetrating keratoplasty, and 1 eye was enucleated.
130 ed tarsorrhaphy, 6 patients (15.4%) required penetrating keratoplasty, and 1 patient required enuclea
137 Aspergillus niger was able to colonize and penetrate manganese nodules embedded in solid medium and
140 ely patrol the tissue and respond swiftly to penetrating microbes, noxious agents, and injurious stim
141 oconjugates (spherical nucleic acids [SNAs]) penetrate mouse skin, three-dimensional (3D) skin equiva
142 d-loop sensory neuroprosthesis utilizing non-penetrating multi-contact cuff electrodes implanted arou
143 nsgenic Nras; bcat* mice, as well as in deep penetrating naevi, a type of human pre-melanoma neoplasm
145 ndo functional materials due to their highly penetrating nature and specific interactions with the nu
151 able BODIPY fluorophore enables the probe to penetrate osteocytic lacunae cavities that are embedded
152 trum intravenous antibiotics with ability to penetrate pancreatic necrosis should be favored (eg, car
154 ng framework, and hybridize it with the cell penetrating peptide (CPP) that allows for effective pene
155 s been previously identified as a novel cell-penetrating peptide (CPP) that is able to efficiently in
156 itin and employed a cyclic polyarginine cell-penetrating peptide (cR(10)) conjugated to the N-terminu
157 itation, we test an arginine-rich Pip6a cell-penetrating peptide and show that Pip6a-conjugated morph
160 t report that documents the benefits of cell-penetrating peptide conjugation to enhance the potential
163 o access targets within cells, a cyclic cell-penetrating peptide is appended to DNA-encoded libraries
166 The linkers are cell compatible; a cell-penetrating peptide that contained this linker was effic
169 cell-permeable by conjugating a cyclic cell-penetrating peptide to their N-terminus, C-terminus, or
170 onjugating an ASO with an arginine-rich cell-penetrating peptide, Pip6a, enhanced delivery, resulting
172 or receptor mediated transcytosis and a cell penetrating peptide-penetratin (Pen) for enhanced cell p
176 epithelial monolayers is conjugation to cell-penetrating peptides (CPPs); however, very little is kno
177 icles bearing phage display peptides or cell-penetrating peptides and expand the receptor repertoire
179 hydrophobic and hydrophilic moments of short penetrating peptides for enhancing mitochondrial localiz
181 r cationic molecules are widely used as cell-penetrating peptides, we studied several cationic polyme
184 MYC peptide (OmoMYC) linked to a functional penetrating 'Phylomer' peptide (FPPa) as a therapeutic s
185 mmunological properties and their ability to penetrate physiological barriers that are impermeable to
186 who underwent FSAK for astigmatism following penetrating (PKP) or deep anterior lamellar keratoplasty
187 Oenococcus oeni was encapsulated into inter-penetrated polymer networks of silica-alginate (SiO(2)-A
188 min, (representing lacrimal drainage) 0.071% penetrated porcine cornea by 60 min and 0.0002% penetrat
190 concentration to affect either lytic or cell-penetrating properties, which are useful for selective d
192 hysin significantly in mice, indicating that penetrating property of HIV-1 Tat protein attributes to
195 ucture based on data collected by the ground-penetrating radar (GPR) onboard the Yutu-2 rover during
197 ow simple analysis of viscous buckles in ice-penetrating radar data can quantify the seawater content
198 On the basis of X-ray structures of a CNS-penetrating reactivator, monoxime RS194B, reversibly bou
199 estion strategy with trypsin and elastase to penetrate regions with a low density of trypsin-cleavage
200 g region 3 (CDR3) elements of V2A11 and V8E6 penetrate RTA's active site and interact with key cataly
202 ial receptor pool with a blood-brain barrier penetrating S1P(1)-selective agonist can further reduce
204 he HPV16 L2 retromer-binding site and a cell-penetrating sequence enter cells, sequester retromer fro
205 nt that is spatially heterogeneous, at times penetrating several nanometers into the lattice, in a ma
208 acking allow the microneedles to efficiently penetrate skin under compression, and to snap off under
211 y for the sensing medium to support a highly-penetrating surface plasmon evanescent field that extend
212 ty of neurotumors physically enables GBMs to penetrate surrounding tissue, a phenomenon similar to Sa
216 nsporters, such nanocapsules can effectively penetrate the BBB and deliver the therapeutics to the CN
218 due to the failure of infused antibiotics to penetrate the bladder epithelium and accumulate to high
219 antibiotic treatments, which are not able to penetrate the bladder wall and accumulate to an effectiv
220 mproved water solubility, and the ability to penetrate the blood brain barrier (BBB), which indicate
225 ipherally administered NCAM peptide mimetics penetrate the brain and alter the behavior of standardiz
226 is raises the question of whether AV-101 can penetrate the brain and engage the NMDAR and KP effectiv
228 were low-molecular organosilicons enable to penetrate the cell wall as well as chemicals with functi
230 ility and morphology but are equally able to penetrate the cumulus and fertilize the egg once at the
232 esult in substantial Zn diffusion, which can penetrate the full absorber thickness already at moderat
233 ge intestine, whereas A. lumbricoides larvae penetrate the gut mucosa and migrate through the liver a
234 ped polyomavirus simian virus 40 (SV40) must penetrate the host endoplasmic reticulum (ER) membrane t
237 r, we applied dextran blue, which should not penetrate the intact cornea and did not do so in our mod
238 uding coxsackievirus B3 (CVB3), successfully penetrate the intestine to initiate infection and spread
239 ineral oil, in comparison, allowed Fe(VI) to penetrate the layer within shorter lengths of time and s
241 ires a contiguous cell layer but since teeth penetrate the oral epithelium, a modified barrier has ev
242 strated that cells derived from the periderm penetrate the oropharyngeal cavity via the mouth and via
247 cells infused into the renal artery did not penetrate the renal vascular network to generate vessels
251 normal exhibited normal motility, and could penetrate the zona pellucida and bind to the oolemma.
254 of action, we showed that systemic exendin-4 penetrated the brain and bound putative GLP-1 receptors
260 y aimed to understand whether UV-B radiation penetrates the fruit skin and is able to induce metaboli
263 lysis revealed that JM4 forms a hairpin that penetrates the kinase active site, reinforcing autoinhib
264 ity, and neutron reflectometry shows that it penetrates the membrane deeply, whereas gamma-aminobutyr
265 ow that Pt-3 effectively enters breast CSCs, penetrates the nucleus, induces genomic DNA damage, and
267 nical studies show that brolucizumab readily penetrates the retina to reach the retinal pigment epith
274 facilitate transdermal delivery of drugs by penetrating the outer layer of the skins surface, absorb
275 panosomes reach the ectoperitrophic space by penetrating the peritrophic matrix in the anterior midgu
276 corpion toxin (WaTx) that activates TRPA1 by penetrating the plasma membrane to access the same intra
277 l pouch cells result in dendrites completely penetrating the single-layer separator causing high shor
278 CD11b/CD18, or Mac-1) of myeloid phagocytes, penetrates their plasma membrane, and delivers the AC en
279 es for covalent drug conjugation can rapidly penetrate through the full thickness of cartilage in hig
280 ic of acoustic-gravity waves: the ability to penetrate through the sea-bottom, which modifies the pro
281 udied as a sequence of steps: sperm bind and penetrate through the zona pellucida of the egg, adhere
283 f the plateau that the Farallon slab surface penetrated through the proto-plateau SCLM at much shallo
285 rong induced electric field, in the process, penetrates through the narrow hole and generates highly
287 cularly their motility, allow microrobots to penetrate tissues and reach cancers more efficiently.
289 of antibodies as targeting molecules or cell-penetrating tools has emerged at the forefront of pharma
291 ged by endovascular means for both blunt and penetrating trauma (R = 0.92, P < 0.01; and R = 0.86, P
293 t as self-blockage site of posterior scleral penetrating trauma, allowed for surgical stabilization a
295 nctions of macrophages and their capacity to penetrate tumors(5), we genetically engineered human mac
296 d certain histidine residues in the membrane-penetrating VP5 protein that detect cellular pH, leading
299 rauma without previous instrumental signs of penetrating wound and complete visual restoration after