ライフサイエンスコーパス: penicillin-binding protein

1 proteins, and SpoVD, a nonessential class B penicillin binding protein.

2 gene that encodes the methicillin-resistant penicillin binding protein.

3 is a bacterial low molecular weight class C penicillin-binding protein.

4 lysine to 8.0-8.5 from that of the parental penicillin-binding protein.

5 values was found for a beta-lactam-resistant penicillin-binding protein.

6 ally encodes a high-molecular-weight class A penicillin-binding protein.

7 tro and in vivo with the major bi-functional penicillin-binding protein.

8 d scoring against the crystal structure of a penicillin-binding protein.

9 amidases, or any of the low-molecular-weight penicillin binding proteins.

10 d-Ala analogues and to prevent the action of penicillin binding proteins.

11 ocks peptidoglycan polymerization by class A penicillin-binding proteins.

12 eB promotes the transglycosylase activity of penicillin-binding proteins.

13 milarity to a noncatalytic domain of class B penicillin-binding proteins.

14 cellular multiprotein complexes that include penicillin-binding proteins.

15 the enzyme targets of the beta-lactams, the penicillin-binding proteins.

16 to any other beta-lactamases or the related penicillin-binding proteins.

17 g all active-site serine beta-lactamases and penicillin-binding proteins.

18 ding determinations for penicillin-sensitive penicillin-binding proteins.

19 ated by structural changes in transpeptidase penicillin-binding proteins.

20 biosynthesis and one encodes a homologue of penicillin-binding proteins.

21 ptibility to penicillin: ponA, which encodes penicillin-binding protein 1 (PBP 1), and the pilMNOPQ o

22 n through recombination events involving the penicillin binding protein 1a (pbp1a) gene, have cpsB se

23 ppressors eliminates the function of class A penicillin binding protein 1a (PBP1a).

24 this is caused by RSV G glycoprotein binding penicillin binding protein 1a.

25 ng the Rcs stress response and those lacking penicillin binding protein 1B (PBP1B) or LpoB could not

26 9 cells lacking the bifunctional aPBP PBP1B (penicillin binding protein 1B) lyse during exponential g

27 Penicillin-binding protein 1b (PBP 1b) of the gram-posit

28 examined the inhibition of Escherichia coli penicillin-binding protein 1b (PBP1b) by moenomycin as w

29 Inhibiting penicillin binding protein 2 (PBP 2) alone produced the

30 Isolates harbouring the mosaic penicillin binding protein 2 (PBP2)-considered a key mec

31 inhibits the cell elongation transpeptidase penicillin binding protein 2 in Escherichia coli, exhibi

32 ) on Mueller-Hinton agar, an immunoassay for penicillin binding protein 2' (Denka Seiken Co., Tokyo,

33 Mutations in penicillin-binding protein 2 (PBP 2) encoded by mosaic p

34 Penicillin-binding protein 2 (PBP2) also formed band-lik

35 n synthesis or peptidoglycan crosslinking by penicillin-binding protein 2 (PBP2) are unable to initia

36 Penicillin-binding protein 2 (PBP2) from N. gonorrhoeae

37 The essential function of penicillin-binding protein 2 (PBP2) in methicillin-susce

38 antibiotic with high selective affinity for penicillin-binding protein 2 (PBP2) of Staphylococcus au

39 esistance is conferred by mosaic variants of penicillin-binding protein 2 (PBP2) that have diminished

40 by acquiring a mosaic penA allele, encoding penicillin-binding protein 2 (PBP2) variants containing

41 ting cells with amdinocillin, which inhibits penicillin-binding protein 2 (PBP2), allowed PG glycan s

42 ired for cell division, or in the absence of penicillin-binding protein 2 (PBP2), which is required f

43 linic, and presence or absence of the mosaic penicillin-binding protein 2 (penA) allele.

44 activity against NDMs, AVI can interact with penicillin-binding protein 2 in a manner that may influe

45 rphisms of the penA gene encoding a modified penicillin-binding protein 2.

46 The expression of penicillin binding protein 2a (PBP2a) is the basis for t

47 The penicillin binding protein 2a (PBP2a) latex agglutinatio

48 d, Basingstoke, United Kingdom) that detects penicillin binding protein 2a (PBP2a) with MicroScan con

49 S. aureus is the production of a distinctive penicillin binding protein 2a (PBP2a), which exhibits lo

50 We studied the utility of performing a penicillin binding protein 2a latex agglutination (PBP-L

51 us infection in which a false-positive rapid penicillin binding protein 2a latex test in conjunction

52 CA-MRSA typically express less penicillin-binding protein 2a (encoded by mecA), allowin

53 onferring beta-lactam antibiotic resistance, penicillin-binding protein 2A (encoded by the mecA gene)

54 enzymes, and the other is the expression of penicillin-binding protein 2a (PBP 2a), which is not sus

55 acquisition of the gene mecA, which encodes penicillin-binding protein 2a (PBP 2a).

56 f a beta-lactamase, and the other is that of penicillin-binding protein 2a (PBP 2a).

57 hylococcus aureus (MRSA), is able to inhibit penicillin-binding protein 2a (PBP2a) by triggering an a

58 The performance of a rapid penicillin-binding protein 2a (PBP2a) detection assay, t

59 ecA promoter region that lowers mecA-encoded penicillin-binding protein 2a (PBP2a) expression, and in

60 antibiotics, the oxadiazoles, which inhibit penicillin-binding protein 2a (PBP2a) of MRSA.

61 Penicillin-binding protein 2a (PBP2a) of Staphylococcus

62 n-SASS through acquisition and expression of penicillin-binding protein 2a (PBP2a) represents a signi

63 (eg, oxacillin) depends on the production of penicillin-binding protein 2a (PBP2a), encoded by mecA M

64 ith monoclonal antibody prepared against the penicillin-binding protein 2A (PBP2A), i.e., the gene pr

65 An enzyme, called penicillin-binding protein 2a (PBP2a), is brought into t

66 beta-Lactamase and penicillin-binding protein 2a mediate staphylococcal res

67 The Alere penicillin-binding protein 2a test accurately detected a

68 n is derepressed for both beta-lactamase and penicillin-binding protein 2a.

69 d to monoclonal antibodies (MAb) specific to penicillin-binding-protein 2a of methicillin resistant (

70 The assay amplifies a lytA gene target and a penicillin binding protein 2b (pbp2b) gene target in pen

71 Depletion of penicillin-binding protein 2B (PBP2B) in B. subtilis cel

72 ntigen (SAG1350), lipoprotein (SAG0971), and penicillin-binding protein 2b (SAG0765) each bound to ME

73 antigen (SAG1350), a lipoprotein (SAG0971), penicillin-binding protein 2b (SAG0765), glyceraldehyde-

74 ctrophoresis, multilocus sequence typing and penicillin-binding protein 2b amplicon-restriction profi

75 trains had single amino acid replacements in penicillin-binding protein 2X (PBP2X), a major target of

76 tuting) mutation in the pbp2x gene, encoding penicillin-binding protein 2X (PBP2X).

77 that inactivation of the ftsI gene product, penicillin binding protein 3, by either beta-lactam anti

78 A soluble form of penicillin-binding protein 3 (PBP 3) from Neisseria gono

79 rict linkage disequilibrium in the S. aureus penicillin-binding protein 3 (pbp3) gene were also found

80 s that prevent peptidoglycan crosslinking by penicillin-binding protein 3 (PBP3/FtsI) initiate polari

81 Penicillin-binding protein 3 (PBP3; also called FtsI) is

82 glycan synthesis by the transpeptidase FtsI (penicillin-binding protein 3).

83 Previously, by targeting penicillin-binding protein 3, Pseudomonas-derived cephal

84 substrate preferences for the endopeptidase penicillin binding protein 4.

85 Penicillin-binding protein 4 (PBP4) is a nonessential tr

86 evate AmpC expression is loss of function of penicillin-binding protein 4 (PBP4).

87 Penicillin-binding protein 5 (PBP 5) from Escherichia co

88 Penicillin-binding protein 5 (PBP 5) of Escherichia coli

89 Penicillin-binding protein 5 (PBP 5) of Escherichia coli

90 Penicillin-binding protein 5 (PBP 5) of Escherichia coli

91 Penicillin-binding protein 5 (PBP 5) of Escherichia coli

92 The contribution of penicillin-binding protein 5 (PBP5) and the PBP5 synthes

93 reveals a fitness advantage for mutations in penicillin-binding protein 5 (pbp5) that increase resist

94 Finally, deletion of penicillin-binding protein 5 from amidase mutants exacer

95 n enterococcal strain devoid of low-affinity penicillin-binding protein-5 (significantly increasing i

96 Penicillin-binding protein 6 (PBP6) is one of the two ma

97 hich encodes the putative low-molecular-mass penicillin-binding protein 7/8 (PBP-7/8).

98 Penicillin-binding protein A (PBPA) is a class B penicil

99 contributes to the spatiotemporal control of penicillin-binding protein activity.

100 MreC controls the spatial orientation of the penicillin binding proteins and a lytic transglycosylase

101 StkP localization depends on its penicillin-binding protein and Ser/Thr-associated domain

102 (ECD) consists of four repeats homologous to penicillin-binding protein and serine/threonine kinase a

103 Both the PonA2 and PonA3 proteins contain a penicillin-binding protein and serine/threonine protein

104 ng of 1.2 million compounds for binding to a penicillin-binding protein and the subsequent demonstrat

105 Fluorescein-meropenem binds both penicillin-binding proteins and beta-lactam sensors and

106 treptococcus pneumoniae contain low affinity penicillin-binding proteins and often also produce abnor

107 ral non-beta-lactam antibiotic that inhibits penicillin-binding proteins and serine beta-lactamases.

108 result from the presence of a reduced set of penicillin-binding proteins and the absence of a wblC ge

109 The family of bacterial Penicillin-binding-protein And Serine/Threonine kinase-A

110 ansmembrane proteins that have extracellular penicillin-binding-protein and serine/threonine kinase-a

111 other than inhibition of protein synthesis, penicillin-binding proteins, and DNA topoisomerases; amo

112 bacterial target sites such as the ribosome, penicillin-binding proteins, and topoisomerases in a pha

113 e glycan strands and crosslink them: class A penicillin-binding proteins (aPBPs) and complexes of SED

114 e auxiliary role of the bifunctional class A penicillin-binding proteins (aPBPs) as well as the L,D-t

115 ound the cell circumference, whereas class A penicillin-binding proteins (aPBPs) do not.

116 wall assembly mechanism assume that class A penicillin-binding proteins (aPBPs), the targets of peni

117 of the cell: the Rod complex and the class-A penicillin-binding proteins (aPBPs).

118 Beta-lactamases and penicillin-binding proteins are bacterial enzymes involv

119 The penicillin-binding proteins are essential enzyme catalys

120 ansferases that work in concert with class B penicillin-binding proteins (bPBPs) to build the bacteri

121 MRSA strains have acquired a non-native penicillin-binding protein called PBP2a that cross-links

122 ces R61 dd-peptidase, a functional model for penicillin-binding proteins, catalyzes the hydrolysis an

123 erived genomes possess mutations targeting a penicillin-binding protein coding gene (mrcA) that had n

124 We report herein the structure of a penicillin-binding protein complexed with a cephalospori

125 While bacterial d,d-transpeptidases (penicillin-binding proteins) employ a nucleophilic serin

126 ked by the pbp2x and pbp1a genes, coding for penicillin-binding proteins, enzymes involved in cell wa

127 as identified previously for genes encoding penicillin binding proteins, evolved by recombination wi

128 s for the direct detection of IgE and of the penicillin-binding protein from Staphylococcus aureus (P

129 ferase domain of class A high-molecular-mass penicillin-binding proteins from different species.

130 ulosis CrgA with FtsZ, FtsQ, and the class B penicillin-binding proteins, FtsI (PBPB) and PBPA.

131 somal macrorestriction profile and identical penicillin-binding-protein gene restriction profiles cha

132 A included the capsular locus and the nearby penicillin-binding protein genes pbp2x and pbp1a.

133 , sometimes including the capsular locus and penicillin-binding protein genes, predated both vaccine

134 High-molecular-mass penicillin-binding proteins (HMM PBPs) are essential for

135 glycan synthesis and degradation mediated by penicillin binding proteins in the forespore and a cell

136 acylation and provide further evidence that penicillin-binding proteins in apo form can occupy diffe

137 of carbenicillin (Cb) to assess the role of penicillin-binding proteins in growth and cell division.

138 r, these results identify a novel role for a penicillin-binding-protein in compartmentalizing a bacte

139 toward oxacillin, an antibiotic that targets penicillin-binding proteins, in both methicillin-sensiti

140 The transglycosylase domain of penicillin-binding proteins is especially important, as

141 s the archetypal class C, low molecular mass penicillin binding protein (LMM-PBP) and possesses both

142 Four low-molecular-weight penicillin binding proteins (LMW PBPs) of Escherichia co

143 The biological roles of low molecular weight penicillin-binding proteins (LMW PBP) have been difficul

144 chia coli cells lacking low-molecular-weight penicillin-binding proteins (LMW PBPs) exhibit morpholog

145 ane, these new cell wall components regulate penicillin-binding proteins located at the inner membran

146 on is penicillin sensitive and assigned to a penicillin-binding protein motif.

147 Certain penicillin binding protein mutants of Escherichia coli g

148 erved in Gram-positive bacterial species for penicillin-binding protein mutants.

149 The high-molecular mass penicillin binding proteins of bacteria catalyze in sepa

150 ence exceeds that observed for blocks in the penicillin-binding proteins of S. pneumoniae or in many

151 This is not usually observed for penicillin-binding proteins, or for the related serine b

152 otluri et al. show that low molecular weight penicillin binding proteins, particularly PBP5, have a r

153 that controls activity of the bi-functional penicillin binding protein PBP A1, we discovered that Gp

154 Penicillin-binding protein PBP 2B is a key cell division

155 ates also potently inhibit the non-essential penicillin-binding protein PBP 5 by the same mechanism o

156 Penicillin binding protein (PBP) 5, a DD-carboxypeptidas

157 nts for acylation and deacylation of soluble penicillin binding protein (PBP) constructs by compounds

158 onstructed a set of mutants from which eight penicillin binding protein (PBP) genes were deleted in 1

159 The approach uses a recombinant bacterial penicillin binding protein (PBP) tagged by an N-terminal

160 nctional enzyme, known as a high MW, class A penicillin binding protein (PBP).

161 rmined that expression of the well-conserved penicillin-binding protein (PBP) 1A, prevented LOS-defic

162 erved heterogeneous localization dynamics of penicillin-binding protein (PBP) 1A, the synthase predom

163 otein LpoB is required for the activation of penicillin-binding protein (PBP) 1B, which is a major, b

164 y cell division protein FtsZ, which recruits penicillin-binding protein (PBP) 2.

165 Penicillin-binding protein (PBP) 2a latex agglutination

166 y functional assays, showing binding of 2 to penicillin-binding protein (PBP) 2a.

167 We evaluated pbp expression, levels of penicillin-binding protein (PBP) 5 (PBP5) and beta-lacta

168 We evaluated the impact of resistant penicillin-binding protein (PBP) allele acquisition on t

169 The gene product of mecA from MRSA is a penicillin-binding protein (PBP) designated PBP 2a.

170 of Streptococcus pneumoniae contain altered penicillin-binding protein (PBP) genes and occasionally

171 osporin drug ceftazidime caused by loss of a penicillin-binding protein (PBP) in a Gram-negative baci

172 Expression of penicillin-binding protein (PBP) in E. chaffeensis was a

173 For the most potent combinations identified, penicillin-binding protein (PBP) inhibition profiles wer

174 that inactivation of the major bi-functional penicillin-binding protein (PBP) PBP1 of B. subtilis res

175 Mycobacterium tuberculosis is a class B-like penicillin-binding protein (PBP) that is not essential f

176 ed motifs of a class B high-molecular-weight penicillin-binding protein (PBP), including the transpep

177 We report the first crystal structures of a penicillin-binding protein (PBP), PBP3, from Pseudomonas

178 of this resistance mechanism: the "acquired" penicillin-binding protein (PBP)-2A, which has unusual l

179 e T. pallidum 47-kDa lipoprotein (Tp47) as a penicillin-binding protein (PBP).

180 The surface-localized penicillin-binding protein (PBP)1a, encoded by ponA, is

181 azolinones to bind to the allosteric site of penicillin-binding protein (PBP)2a, resulting in opening

182 The low-molecular-weight (LMW) penicillin-binding protein, PBP 5, plays a dominant role

183 eptidase (TP) activities of Escherichia coli penicillin binding proteins PBP1A and PBP1B and show tha

184 Among these pH specialists are the class A penicillin binding proteins PBP1a and PBP1b; defects in

185 Cell wall morphogenetic protein RodA and penicillin-binding protein PBP1a also change their spati

186 ponA encodes an extra-cytoplasmic penicillin-binding protein PBP1a, a newly identified vir

187 is model, we found that a surface-associated penicillin-binding protein (PBP1a), encoded by ponA, pla

188 cholerae high-molecular-weight bifunctional penicillin binding proteins, PBP1a and PBP1b, in the fit

189 Staphylococcus aureus penicillin-binding protein PBP2 is an enzyme involved in

190 utions in the transglycosylase domain of the penicillin-binding protein Pbp2, and these changes resto

191 The penicillin-binding protein PBP2, which is commonly brand

192 he expression of mecA, the gene encoding the penicillin binding protein PBP2a.

193 istant S. aureus strain expressing the extra penicillin-binding protein PBP2A, a protein of extraspec

194 of the crystal structure of the low-affinity penicillin-binding protein PBP2a, which mediates beta-la

195 mediated by mecA and blaZ, genes encoding a penicillin-binding protein (PBP2a) with low beta-lactam

196 e acquisition of a nonnative gene encoding a penicillin-binding protein (PBP2a), with significantly l

197 n of the mecA gene, which encodes an altered penicillin binding protein, PBP2a.

198 ls and is catalyzed by the essential class B penicillin-binding protein PBP2b transpeptidase (TP).

199 quisition of a novel transposon carrying the penicillin binding protein Pbp2c, responsible for resist

200 ates had a single amino acid substitution in penicillin-binding protein PBP2X that conferred a 2-fold

201 he relative localization patterns of class B penicillin-binding proteins Pbp2x and Pbp2b were used as

202 al sideromimic conjugated compounds bound to penicillin binding proteins PBP3 and PBP1a from Pseudomo

203 Penicillin-binding protein PBP3, a key therapeutic targe

204 ght to work in concert with the PG synthases penicillin-binding proteins PBP3 and PBP1b.

205 utations in genes for the low-molecular-mass penicillin-binding proteins PBP3 and PBP4.

206 g a forward genetics approach, we identify a penicillin-binding-protein, PbpC, which is required for

207 precise temporal and spatial organization of penicillin binding proteins (PBPs) and associated protei

208 Penicillin binding proteins (PBPs) and beta-lactamases a

209 Penicillin binding proteins (PBPs) are responsible for s

210 depends not only on the reduced affinity of penicillin binding proteins (PBPs) but also on the funct

211 isolated from strains lacking three or four penicillin binding proteins (PBPs) but not from a mutant

212 Penicillin binding proteins (PBPs) catalyze steps in the

213 Penicillin binding proteins (PBPs) catalyzing transpepti

214 at Escherichia coli mutants lacking multiple penicillin binding proteins (PBPs) display extensive mor

215 Beta-lactam antibiotics inhibit penicillin binding proteins (PBPs) involved in peptidogl

216 iotics, the transpeptidase activity of their penicillin binding proteins (PBPs) is lost as a result o

217 e been ascribed to the high-molecular-weight penicillin binding proteins (PBPs) of Escherichia coli,

218 Escherichia coli has 12 recognized penicillin binding proteins (PBPs), four of which (PBPs

219 al targets are the transpeptidase domains of penicillin binding proteins (PBPs), which catalyze the c

220 f the bacterial cell wall, is synthesised by penicillin binding proteins (PBPs).

221 he surrounding medium, a process mediated by penicillin binding proteins (PBPs).

222 Peptidoglycan assembly relies on penicillin-binding proteins (PBPs) acting in concert wit

223 Penicillin-binding proteins (PBPs) and beta-lactamases a

224 ation rates for acyl-enzyme intermediates in penicillin-binding proteins (PBPs) and beta-lactamases h

225 d low throughput assays of the activities of penicillin-binding proteins (PBPs) and beta-lactamases,

226 vel gamma-lactam pyrazolidinone that targets penicillin-binding proteins (PBPs) and incorporates a si

227 bacterial cell wall synthesis by binding of penicillin-binding proteins (PBPs) and inhibiting peptid

228 nal d,d-transpeptidases belonging to class B penicillin-binding proteins (PBPs) and monofunctional gl

229 or decades, it was thought that only class A penicillin-binding proteins (PBPs) and related enzymes e

230 We determined the patterns of penicillin-binding proteins (PBPs) and the peptidoglycan

231 The penicillin-binding proteins (PBPs) are a set of enzymes

232 Penicillin-binding proteins (PBPs) are bacterial enzymes

233 High molecular weight penicillin-binding proteins (PBPs) are bifunctional enzy

234 Penicillin-binding proteins (PBPs) are enzymes involved

235 High-molecular-weight penicillin-binding proteins (PBPs) are essential integra

236 Penicillin-binding proteins (PBPs) are involved in the f

237 Penicillin-binding proteins (PBPs) are involved in the s

238 Class A penicillin-binding proteins (PBPs) are large, bifunction

239 Penicillin-binding proteins (PBPs) are responsible for t

240 Penicillin-binding proteins (PBPs) are the molecular tar

241 Penicillin-binding proteins (PBPs) are the targets of th

242 The penicillin-binding proteins (PBPs) are ubiquitous bacter

243 Penicillin-binding proteins (PBPs) are ubiquitous bacter

244 subtilis, where it plays a role in shuttling penicillin-binding proteins (PBPs) between septal and si

245 Class B penicillin-binding proteins (PBPs) carry a transpeptidas

246 Penicillin-binding proteins (PBPs) catalyze the crosslin

247 Penicillin-binding proteins (PBPs) catalyze the final, e

248 The bacterial DD-peptidases or penicillin-binding proteins (PBPs) catalyze the formatio

249 the first crystal structures of A. baumannii penicillin-binding proteins (PBPs) covalently inactivate

250 fluorescent protein (GFP) fusions to all 11 penicillin-binding proteins (PBPs) expressed during vege

251 iotics is the D,D-transpeptidase activity of penicillin-binding proteins (PBPs) for synthesis of 4-->

252 Escherichia coli low molecular mass penicillin-binding proteins (PBPs) include PBP4, PBP5, P

253 The four class A penicillin-binding proteins (PBPs) of Bacillus subtilis

254 The penicillin-binding proteins (PBPs) polymerize and modify

255 mutants in Escherichia coli lacking multiple penicillin-binding proteins (PBPs) produce misshapen cel

256 ew transpeptidase (TP) activity catalyzed by penicillin-binding proteins (PBPs) separate into a pair

257 erence affects the cross-linking activity of penicillin-binding proteins (PBPs) that assemble peptido

258 ave long been known to target enzymes called penicillin-binding proteins (PBPs) that build the bacter

259 Penicillin-binding proteins (PBPs) were long considered

260 crescentus, MreC physically associates with penicillin-binding proteins (PBPs) which catalyse the in

261 jor synthases of this exoskeleton are called penicillin-binding proteins (PBPs)(1,2).

262 Production of low-affinity forms of penicillin-binding proteins (PBPs), although essential,

263 Penicillin-binding proteins (PBPs), biosynthetic enzymes

264 In Escherichia coli , the bifunctional penicillin-binding proteins (PBPs), PBP1A and PBP1B, pla

265 at MreC Interacts with high-molecular-weight penicillin-binding proteins (PBPs), rather than with low

266 ne of very few compound classes that inhibit penicillin-binding proteins (PBPs), SBLs and, as recentl

267 The Bacillus subtilis genome encodes 16 penicillin-binding proteins (PBPs), some of which are in

268 Penicillin-binding proteins (PBPs), the target enzymes o

269 Synthases called penicillin-binding proteins (PBPs), the targets of penic

270 To identify new compounds that inhibit penicillin-binding proteins (PBPs), which are proven tar

271 The bifunctional high molecular weight (HMW) penicillin-binding proteins (PBPs), which contain both g

272 pressing variants of its target enzymes, the penicillin-binding proteins (PBPs), with many amino acid

273 hesized by polysaccharide polymerases called penicillin-binding proteins (PBPs).

274 ycan layer by a series of enzymes called the penicillin-binding proteins (PBPs).

275 l, the synthesis of which is orchestrated by penicillin-binding proteins (PBPs).

276 ll (peptidoglycan) synthesizing complexes of penicillin-binding proteins (PBPs).

277 catalyzed by high-molecular-weight, class A penicillin-binding proteins (PBPs).

278 lytic activity, these key targets are called penicillin-binding proteins (PBPs).

279 doglycan (PG) exoskeleton synthesized by the penicillin-binding proteins (PBPs).

280 ll wall biosynthesis through inactivation of penicillin-binding proteins (PBPs).

281 tagged mimics of the endogenous substrate of penicillin-binding proteins (PBPs).

282 is of the bacterial cell wall (also known as penicillin-binding proteins, PBPs) have evolved to bind

283 an additional gene encoding a third class A penicillin-binding protein, PonA3, which is a paralog of

284 ntrol levels of a beta-lactamase, PC1, and a penicillin-binding protein poorly acylated by beta-lacta

285 Penicillin-binding proteins represent well-established,

286 to different target enzymes (DNA gyrase and penicillin-binding proteins, respectively) and in 41 sin

287 ent that preferentially binds to the altered penicillin binding protein responsible for diminished pe

288 elevant class A, C and D beta-lactamases and penicillin-binding proteins, resulting in intrinsic anti

289 demonstrates that the high-molecular-weight penicillin-binding protein SpoVD, which contains two exp

290 can cell wall is synthesized by bifunctional penicillin-binding proteins such as PBP1b that have both

291 BP2 co-immunoprecipitated with several other penicillin-binding proteins, suggesting that these prote

292 cillin-binding protein A (PBPA) is a class B penicillin-binding protein that is important for cell di

293 that link the cytoskeletal elements with the penicillin-binding proteins that carry out peptidoglycan

294 These enzymes are members of the family of penicillin-binding proteins, the targets of beta-lactam

295 is the first purified gram-positive class A penicillin-binding protein to show good transglycosylase

296 oss-linked between adjacent wall peptides by penicillin-binding proteins to confer robustness and fle

297 genus include the actin homolog MreB, three penicillin-binding proteins, two L,D-transpeptidases, a

298 For many years, the penicillin-binding proteins were thought to be the key e

299 lied to other classes of beta-lactamases and penicillin-binding proteins with the SXXK motif.

300 ional members of the sigma(X) regulon, pbpX (penicillin-binding protein), ywnJ, the dlt operon (D-ala