戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1 neumonia prophylaxis (with cotrimoxazole and pentamidine).
2 iltefosine, paromomycin, amphotericin B, and pentamidine).
3 , miltefosine (hexadecylphosphocholine), and pentamidine.
4 in activity compared to the control compound pentamidine.
5 nosomiasis such as melarsoprol (Arsobal) and pentamidine.
6  20 (70%, 95% CI 48-85.5%) for intralesional pentamidine.
7 ss effective alternatives, often aerosolized pentamidine.
8 istance to paromomycin, amphothericin B, and pentamidine.
9 of 31 [71%]) or 2 doses (31 of 31 [100%]) of pentamidine.
10 ypanosomes often display cross-resistance to pentamidine.
11 nce to existing diamidine therapies, such as pentamidine.
12 t increase was observed with the addition of pentamidine.
13 al and antileishmanial potencies compared to pentamidine.
14 , P. falciparum, and L. donovani compared to pentamidine.
15 rs were more active against L. donovani than pentamidine.
16 vity against L. donovani superior to that of pentamidine.
17  into TbAQP3 renders the latter permeable to pentamidine.
18 tients) vs a positive control (intralesional pentamidine; 20 patients) against L. braziliensis CL in
19 entify the structural determinants that make pentamidine a permeant although most other diamidine dru
20                                              Pentamidine, a bivalent aromatic diamidine, interacts wi
21        Sixty years after the introduction of pentamidine, a large effort is being made to develop a n
22  S100B/RAGE/NFkappaB-dependent manner, since pentamidine, a S100B inhibitor, prevented 5-FU-induced n
23 n to the (AATT)2 binding site, netropsin and pentamidine acquire 26+/-3 and 34+/-2 additional waters
24 tion, plasma membrane P-type H(+)-ATPases to pentamidine action, and trypanothione and several putati
25 ropane (1) was over 25-fold more potent than pentamidine against the drug-resistant isolate KETRI 243
26 hat has been shown to be more effective than pentamidine against the Pneumocystis carinii pathogen in
27                                              Pentamidine also significantly reduced the formation of
28 t in contrast to hexadecylphosphocholine and pentamidine, AmB induced gene expression of the inflamma
29 structure illustrates, for the first time, a pentamidine analog capable of binding the "open" form of
30 uded by residue Phe88, but for an asymmetric pentamidine analogue ((Ca)S100B.17), this same channel w
31                                For symmetric pentamidine analogues ((Ca)S100B.5a, (Ca)S100B.6b) a cha
32 tudies were therefore completed here with 23 pentamidine analogues, and X-ray structures of (Ca)S100B
33 se data support a model where dual action of pentamidine and chlorpromazine in mitosis results in syn
34 larsoprol and diamidine compounds similar to pentamidine and furamidine are primarily taken up by try
35  bound to two cytotoxic bivalent diamidines, pentamidine and hexamidine.
36 hing was employed to improve the efficacy of pentamidine and Hoechst 33258 ligands that have been sho
37 strate a major role for aquaglyceroporins in pentamidine and melarsoprol cross-resistance.
38 rypanosomal activities comparable to that of pentamidine and melarsoprol.
39 itrypanosomal efficacy comparable to that of pentamidine and melarsoprol.
40 porin AQP2 are associated with resistance to pentamidine and melarsoprol.
41            We identified the small molecules pentamidine and neomycin B as compounds that disrupt MBN
42            The first-line treatment options, pentamidine and nifurtimox-eflornithine combination ther
43 e uptake that was sensitive to inhibition by pentamidine and proton ionophores.
44   Twenty two compounds were more potent than pentamidine and seven dications were more effective than
45 ders cells sensitive to both melarsoprol and pentamidine and that loss of AQP2 function could explain
46                                 Diamidine 1 (pentamidine) and 65 analogues (2-66) have been tested fo
47 istic combination of an antiparasitic agent, pentamidine, and a phenothiazine antipsychotic, chlorpro
48 High-affinity substrates included berberine, pentamidine, and amisulpride, while epinephrine and aten
49   Twenty-six compounds were more active than pentamidine, and seven dications demonstrated increased
50 midino-2-phenylindole (DAPI), netropsin, and pentamidine are minor groove binders that have terminal
51   After protocol implementation, aerosolized pentamidine-associated costs were reduced.
52 l analysis to locate an interaction site for pentamidine at phenylalanine 656, a crucial residue in t
53  how hERG surface expression is disrupted by pentamidine at the cellular and molecular levels.
54 pyl analogue 7 showed toxicity comparable to pentamidine at the dosage of 20 micromol/kg/d.
55 mino)-5'-deoxyadenosine (MDL 73811), but not pentamidine, berenil, or methylglyoxyl bis(guanylhydrazo
56 rs Hoechst 33258, 4'-diamino-2-phenylindole, pentamidine, berenil, spermine, and spermidine, were tes
57                        Our data suggest that pentamidine binding to a folding intermediate of hERG ar
58 tween S100B and the drug, and indicates that pentamidine binds into the p53 binding site on S100B def
59                                              Pentamidine binds QacR in a novel fashion whereby one of
60   An NMR-docked model of one such inhibitor, pentamidine, bound to Ca(2+)-loaded S100B was calculated
61  The leak currents were partially blocked by pentamidine but showed negligible inhibition by NASP.
62 kdown in Caco-2 cells decreased AP uptake of pentamidine by approximately 50% but did not alter BL up
63       OCT1 inhibition decreased AP uptake of pentamidine by approximately 50% in all three systems wi
64         Forty-eight cationically substituted pentamidine congeners possessing benzofuran rings were s
65 onophores revealed that PPT1 may be a proton/pentamidine cotransporter.
66                         Although melarsoprol/pentamidine cross-resistance (MPXR) has been an area of
67 ) loss of function was linked to melarsoprol-pentamidine cross-resistance.
68                                              Pentamidine-decreased maturation of WT K(v)11.1 levels w
69                                              Pentamidine delays terminal repolarization in human hear
70 , none significantly impaired sensitivity to pentamidine, diminazene or melarsoprol, relative to the
71  as well as their modulation by temperature, pentamidine, dofetilide and extracellular K(+) .
72 rfloxacin, benzalkonium chloride, cetrimide, pentamidine, etc.) was increased 5- to 30-fold in a Stap
73 minazene, 4',6-diamidino-2-phenylindole, and pentamidine, examine several biophysical and pharmacolog
74  electrophysiological methods, we found that pentamidine exclusively inhibits hERG export from the en
75 ozoal drug 1,5-bis(4-amidinophenoxy)pentane (pentamidine) has been synthesized and tested for in vitr
76  480-fold more potent than the standard drug pentamidine (IC(50) = 5.3 nM).
77  were more potent against P. falciparum than pentamidine (IC(50) = 58 nM), and eight analogues were m
78 models, we observed that targeting SAT1 with pentamidine improved the efficacy of FOLFIRINOX, suggest
79   Replacing TMP/SMX with monthly aerosolized pentamidine in cases of ADR further increased life expec
80                              Diamidines, and pentamidine in particular, have a long history as valuab
81                              The addition of pentamidine in patients who had an ADR to TMP/SMX result
82  approximately 100 times more effective than pentamidine in this animal model.
83  of conformationally restricted congeners of pentamidine in which the flexible pentyl bridge of penta
84 ared with TMP/SMX alone, TMP/SMX followed by pentamidine increased the QALY by 0.07 at an incremental
85                                     The drug pentamidine inhibits calcium-dependent complex formation
86                             Many drugs, like pentamidine, interfere with normal K(v)11.1 forward traf
87                                              Pentamidine is an antiprotozoal compound that clinically
88                                              Pentamidine is an effective antimicrobial agent against
89                   The trypanocidal action of pentamidine is dependent on the rapid, selective accumul
90 s demonstrates that permeation by dicationic pentamidine is energetically favourable in TbAQP2, drive
91                              We propose that pentamidine is the founding member of a novel pharmacolo
92 r with the development of a new oral form of pentamidine isethionate VLX103, led to investigations of
93                 Of the various drugs tested, pentamidine isethionate was most effective against ameba
94 ect of a specific minor groove-binding drug, pentamidine, on hydration dynamics.
95 l lines in vivo more effectively than either pentamidine or chlorpromazine alone.
96  gene affecting resistance to the antibiotic pentamidine, our data support a mitochondrial target for
97                                 Furthermore, pentamidine partially rescued splicing defects of 2 pre-
98 te that TbAQP2's unique architecture permits pentamidine permeation through its central pore and show
99 of an effort to inhibit S100B, structures of pentamidine (Pnt) bound to Ca(2+)-loaded and Zn(2+),Ca(2
100 nts of GluD receptor variants and found that pentamidine potently inhibited GluD2-T649A constitutive
101   Both TMP/SMX alone and TMP/SMX followed by pentamidine prophylaxis strategies dominated the no prop
102                            At the same time, pentamidine reduces surface expression of the cardiac po
103                              Melarsoprol and pentamidine represent the two main classes of drugs, the
104 tional studies using OCT1-specific substrate pentamidine showed transporter-mediated AP but not BL up
105                               Institution of pentamidine therapy for patients with a TMP/SMX ADR incr
106                         We have investigated pentamidine transport by the bloodstream and procyclic l
107 as characterized, but no adenosine-sensitive pentamidine transport could be detected.
108             The remaining 30 to 50% of [(3)H]pentamidine transport was mediated by a low-capacity hig
109 ne was transported by an adenosine-sensitive pentamidine transporter (ASPT1) that displayed a K(m) va
110 was mediated by a low-capacity high-affinity pentamidine transporter (HAPT1) and a high-capacity low-
111 ter (HAPT1) and a high-capacity low-affinity pentamidine transporter (LAPT1), with K(m) values of 36
112 phonium compounds inhibited the low affinity pentamidine transporter.
113    In procyclics, an HAPT1-analog (procyclic pentamidine transporter; PPT1) was characterized, but no
114                                              Pentamidine treatment results in chromosomal segregation
115                 We show in cell culture that pentamidine was able to reverse the missplicing of 2 pre
116 ts Tdp1 more effectively than berenil, while pentamidine was inactive.
117 idine in which the flexible pentyl bridge of pentamidine was replaced by trans-1,2-bismethylenecyclop
118     In bloodstream forms, 50 to 70% of [(3)H]pentamidine was transported by an adenosine-sensitive pe

 
Page Top