ライフサイエンスコーパス: pentavalent

1 Conversely, oxidation of pentavalent 2-Cp* with AgSbF6 affords cationic [Cp*U(NPh

2 s increased since the discontinuation of the pentavalent (ABCDE) botulinum toxoid vaccine by the Cent

3 ements of VP5 subunits required to form both pentavalent and hexavalent capsomeres result in structur

4 al that mAb #9 binds to L1 molecules of both pentavalent and hexavalent capsomeres.

5 oups received SMS reminders before scheduled pentavalent and measles immunisation visits.

6 The product of this reaction is a pentavalent and monofunctionalized [O = U...OR]+ cation

7 ants, 87% and 86% received the third dose of pentavalent and oral poliovirus vaccine, respectively, b

8 The current standard to assess pentavalent antimonial (SSG) susceptibility of Leishmani

9 ib was significantly more effective than the pentavalent antimonial sodium stibogluconate (70 mg/kg)

10 Pentavalent antimonials (e.g., sodium stibogluconate [SS

11 difficult to cure by chemotherapy (primarily pentavalent antimonials [Sb(V)]).

12 The pentavalent antimonials are considered the first-choice

13 hmaniasis because current treatments such as pentavalent antimonials are toxic and require prolonged

14 iseases, treatment options remain limited to pentavalent antimonials, liposomal amphotericin B, and m

15 ecies during standard of care treatment with pentavalent antimonials.

16 of cutaneous leishmaniasis (CL) in Brazil by pentavalent antimony (Sb v) is associated with a high ra

17 ed by Leishmania braziliensis in Brazil with pentavalent antimony (Sb(v)) is associated with a high r

18 DL is a difficult to cure disease and pentavalent antimony (Sb(v)) is used as standard treatme

19 ial liver parasite killing, and synergy with pentavalent antimony (Sb) chemotherapy.

20 ring disease for which systemic therapy with pentavalent antimony (Sb) is effective but with side eff

21 ishmanicidal effect of conventional therapy, pentavalent antimony (Sb), also requires T cells and end

22 cutaneous leishmaniasis (CL) in Brazil using pentavalent antimony (Sbv) is associated with a high rat

23 responsiveness to conventional chemotherapy (pentavalent antimony [Sb]) requires a T-cell-dependent m

24 The trivalent lanthanides and pentavalent antimony are found to be fully ordered in th

25 Pentavalent antimony compounds have been the mainstay of

26 t LmACR2 is responsible for reduction of the pentavalent antimony in Pentostam to the active trivalen

27 Pentavalent antimony is the conventional treatment; howe

28 lly significant predictors of the failure of pentavalent antimony treatment for cutaneous leishmanias

29 timony tartrate (PAT) and, more importantly, pentavalent antimony-carbohydrate complexes, such as sod

30 Here we report a group of pentavalent antimony-containing small molecule compounds

31 to cutaneous leishmaniasis (CL) treated with pentavalent antimony.

32 (3-nitro-4-hydroxybenzenearsonic acid) is a pentavalent aromatic arsenical that is used as antimicro

33 an environmental toxin that exists mainly as pentavalent arsenate and trivalent arsenite.

34 f trivalent arsenic [As(III)] is oxidized to pentavalent arsenic [As(V)] and bonded to kaolinite, for

35 Pentavalent arsenic [As(V)] was found to be the predomin

36 NMR = 4900 g.mol(-1), D = 1.07) possessing a pentavalent arsenic acid (As(V)) alpha-chain end was tra

37 educed inorganic arsenate but not methylated pentavalent arsenicals.

38 Pentavalent aryl and heteroaryl bis(catechol) silicates

39 lutions contained a mixture of trivalent and pentavalent As species and that the pentavalent species

40 Methylated pentavalent As species are less toxic and are routinely

41 The results for the sums of trivalent and pentavalent As species corresponded well with the refere

42 at would consistently produce single-species pentavalent As standards, which eliminates As speciation

43 artile-range increases in trivalent, but not pentavalent, As species in EUC were positively and signi

44 es rise to an acyclic iodide through which a pentavalent atom of phosphorus can be introduced via the

45 Here we design an ALVAC/Pentavalent B/E/E/E/E vaccine to increase the diversity

46 sera from horses vaccinated with commercial pentavalent bacterin.

47 Pentavalent binding between cholera toxin and gangliosid

48 irus-induced gastroenteritis and, RotaTeq, a pentavalent bovine-based vaccine, and, Rotarix, a monova

49 The absence of mAb 5B6 from the pentavalent capsomeres and its inability to prevent vira

50 al differences for the 5B6 epitope in the 12 pentavalent capsomeres.

51 challenge with S. aureus, where 62.5% of the pentavalent cohort completely cleared the infection, ver

52 terial elimination was found in 66.7% of the pentavalent cohort, while only 8.3% of the control anima

53 prepared via bioconjugation of unimolecular pentavalent construct 1-containing five prostate and bre

54 ffinity and IC50 measured for the respective pentavalent constructs.

55 or = 50 years old were immunized with either pentavalent Corynebacterium diphtheriae C7 (beta197) cro

56 served for large trivalent, tetravalent, and pentavalent counterions.

57 s the trend in coverage for tuberculosis and pentavalent did not significantly differ from zero.

58 For 3 vaccines-pentavalent diphtheria-tetanus-pertussis-hepatitis B-Hae

59 and receipt of five infant vaccines: polio, pentavalent (diphtheria, tetanus, pertussis, hepatitis B

60 313 (95% CI-446 to -179; p<0.0001) fewer for pentavalent during the outbreak.

61 by computational docking of the high-energy, pentavalent form of the substrates to modeled structures

62 ed paddy soils and have higher toxicity than pentavalent forms.

63 rus live-attenuated vaccines, both mono- and pentavalent, generate broadly heterotypic protection.

64 n a higher epitope ratio of the unimolecular pentavalent glycopeptide antigen to the carrier protein

65 ty of the manufacturing-scale formulation of pentavalent HBRV.

66 crobial methylation of inorganic arsenic and pentavalent herbicides such as monosodium methylarsenate

67 The pentavalent human-bovine reassortant rotavirus vaccine (

68 Live pentavalent human-bovine reassortant rotavirus vaccine i

69 Phase III studies of an oral, live, pentavalent, human-bovine reassortant rotavirus vaccine

70 Trivalent (Ia/II/III) and pentavalent (Ia/Ib/II/III/V) vaccines would cover 71/73

71 We measured concentrations of trivalent and pentavalent iAs methyl-As (MAs) and dimethyl-As (DMAs) s

72 The stability of the pentavalent imide can be increased by derivatizing the n

73 uded coverage of measles vaccination and the pentavalent immunisation series, timely vaccination, car

74 here the synthesis and characterization of a pentavalent inhibitor for cholera toxin and Escherichia

75 CT B-subunit (CTB), which is the most potent pentavalent inhibitor for this target reported thus far.

76 g that inhibition of receptor binding by the pentavalent inhibitor is due to 1:1 inhibitor:toxin asso

77 a 1.46 A resolution crystal structure of the pentavalent inhibitor:toxin complex, which shows that th

78 d in order to generate arsanes from tri- and pentavalent inorganic arsenic species (iAs(III), iAs(V))

79 atalyze the interconversion of 5 and 6 via a pentavalent intermediate 8.

80 cts with the carbonyl group upon forming the pentavalent intermediate during phosphodiester hydrolysi

81 change from a stepwise mechanism involving a pentavalent intermediate for poorer leaving groups to a

82 lowed by subsequent formation of an unstable pentavalent intermediate that decomposes into cAMP and p

83 eactions, presumably by participating in the pentavalent intermediate transition state.

84 lly downhill trans-isomer via a hypothesized pentavalent intermediate.

85 ew facile methodology for the preparation of pentavalent iodine compounds using peracetic acid as an

86 idizing reagents belonging to a new class of pentavalent iodine compounds with a pseudobenziodoxole s

87 ed earlier for the corresponding nonbranched pentavalent ligand.

88 Pentavalent ligands, in a "core-linker-finger" modular s

89 Consistent with this observation, the pentavalent lipid MVL5 exhibited lower toxicity and supe

90 assessed the safety and immunogenicity of a pentavalent meningococcal conjugate vaccine targeting se

91 used to immunize mice individually, and as a pentavalent mixture.

92 s Mn(IV) species results in formation of the pentavalent Mn(V) nitride, [(TIMEN(xyl))Mn(N)](2+).

93 are retained by the five arms of the 5256 Da pentavalent MNPG-based inhibitor and that the initial se

94 The resulting pentavalent neoglycoprotein displays an inhibition poten

95 tions may include a 5a" state with nominally pentavalent nitrogen and a 6a" state.

96 is extruded by ArsW, one of only a few known pentavalent organoarsenical efflux permeases, a novel pa

97 ing biosynthesis and extrusion of an unusual pentavalent organoarsenical.

98 Substantial amounts of pentavalent organoarsenicals have been used as herbicide

99 nic compounds are far more toxic than either pentavalent organoarsenicals or inorganic arsenite.

100 to MAs(III) and Rox(III) but not As(III) or pentavalent organoarsenicals.

101 and Rox(III) but not to inorganic As(III) or pentavalent organoarsenicals.

102 y, thus confirming the C(S) symmetry and the pentavalent oxidation state of 2.

103 where it is broadly considered to reside as pentavalent P in phosphate minerals and organic esters.

104 Exceptions to pentavalent P include phosphine--PH3--a trace atmospheri

105 s-hepatitis B-Haemophilus influenzae type b (pentavalent [Penta]) vaccine, measles-rubella (MR) vacci

106 nvolving rapid and reversible formation of a pentavalent peroxide ate complex, prior to rate-limiting

107 osphoenolpyruvate and helps to stabilize the pentavalent phosphate transition state during phosphoryl

108 honic acids by reduction (R-P -> H-P) and to pentavalent phosphoric acids by oxidation.

109 ing the solid effect to effectively polarize pentavalent phosphorus within the phosphate groups of ke

110 Six pentavalent pneumococcal conjugate vaccines (Pn-CRM197)

111 A pentavalent polysaccharide vaccine would cover most meni

112 he lanthanide series, evidence for molecular pentavalent praseodymium species has been observed in th

113 Pentavalent resistance occurred in 120 of 292 isolates (

114 vaccination, as compared with the risk after pentavalent rotavirus vaccination, was 9.4 (95% confiden

115 ain-specific vaccine effectiveness (VE) of a pentavalent rotavirus vaccine (RotaTeq) against rotaviru

116 Routine vaccination of U.S. infants with pentavalent rotavirus vaccine (RV5) began in 2006.

117 t uninfected (HEU) African infants receiving pentavalent rotavirus vaccine (RV5) in a clinical trial.

118 Pentavalent rotavirus vaccine (RV5) was introduced into

119 Pentavalent rotavirus vaccine (RV5), a live, oral attenu

120 RotaTeqTM is a pentavalent rotavirus vaccine based on a bovine rotaviru

121 A quadrivalent precursor to the pentavalent rotavirus vaccine candidate RotaTeq was eval

122 irst low-income African country to introduce pentavalent rotavirus vaccine into its routine national

123 4.92 million for PCV13, $1273.13 million for pentavalent rotavirus vaccine, $415.30 million for Hib v

124 For the pentavalent rotavirus vaccine, 1,301,810 doses were admi

125 Four strains were related to pentavalent rotavirus vaccine, whereas one was related t

126 oncurrent cohort of infants who received the pentavalent rotavirus vaccine.

127 esicles did not transport As(III), MAs(V) or pentavalent roxarsone.

128 rns exist about whether monovalent (RV1) and pentavalent (RV5) rotavirus vaccines provide adequate pr

129 both the monovalent (RV1; 2-dose series) and pentavalent (RV5; 3-dose series) vaccines were introduce

130 li, that confers resistance to trivalent and pentavalent salts of the metalloid arsenic.

131 id R773 produces resistance to trivalent and pentavalent salts of the metalloids arsenic and antimony

132 operons produce resistance to trivalent and pentavalent salts of the metalloids arsenic and antimony

133 vention did not improve measles vaccination, pentavalent series completion, or timely vaccination, an

134 5.2, 26.1]; p < 0.001) and completion of the pentavalent series from 44.2% to 77.5% (aOR 8.9, 95% CI

135 Pk trisaccharide, the in vivo ligand for the pentavalent Shiga-like toxin binding subunit (SLT-1B), w

136 -syn and the 2,3-anti aldehydes form stable, pentavalent silicate intermediates (98 and 100) with PhS

137 he discussed heterocycles either form as the pentavalent species directly or oxidize to this over tim

138 lent and pentavalent As species and that the pentavalent species was approximately 8% more sensitive

139 ated and aromatic arsenicals by oxidation to pentavalent species.

140 In marked contrast, pentavalent SSG, the drug of choice for the treatment of

141 e related metalloid antimony, present in the pentavalent state as a complex in drugs such as sodium s

142 antiquity of this specimen suggests that the pentavalent state of uranium, considered a transient, is

143 uman antibodies from subjects immunized with pentavalent toxoid preparations were detectable at dilut

144 Rather, the pair likely stabilizes the pentavalent transition state necessary for phospho-trans

145 re shows that Mn1 is poised to stabilize the pentavalent transition state of guanylylation while a se

146 e only role for His(632) is to stabilize the pentavalent transition state through hydrogen bonding to

147 horyl oxygen, Arg61 and Asn119 stabilize the pentavalent transition state, and Asn119 also binds to t

148 coordinate the substrates and stabilize the pentavalent transition state.

149 tacking orientation, leading to the presumed pentavalent transition state.

150 itrophenolate), Mg(2+) likely stabilizes the pentavalent transition state.

151 outer membrane MHCs in the reduction of this pentavalent U species but not excluding that of periplas

152 eds via a single electron transfer to form a pentavalent U(V) intermediate which disproportionates to

153 oceeds via a first electron transfer forming pentavalent U(V) species that readily disproportionate.

154 rst through surface-associated U(VI) to form pentavalent U, U(V).

155 hat a first electron transfer occurs to form pentavalent (U(V)) intermediates, but it has not been de

156 olecular dynamics modeling demonstrated that pentavalent uranium is incorporated in the structure of

157 zation of a series of monomeric and dimeric, pentavalent uranyl amide complexes.

158 and characterization of the singly reduced, pentavalent uranyl cation [UO2]+ has been reported.

159 uisition of emission spectra of well-defined pentavalent uranyl complexes using photoluminescence tec

160 Pentavalent uranyl species are crucial intermediates in

161 However, due to the inherent instability of pentavalent uranyl, little is known about its electronic

162 s in the area of tetra- (Ti, Sn, Zr, Hf) and pentavalent (V, Nb, Ta) metal-substituted molecular siev

163 he efficacy of a live, oral bovine rotavirus pentavalent vaccine (BRV-PV, Serum Institute of India) t

164 All children were to receive OPV with pentavalent vaccine (diphtheria, tetanus, pertussis, Hae

165 visit, with infants receiving IPV alongside pentavalent vaccine (which covers diphtheria, tetanus, a

166 oxoid remains an effect vaccine, the current pentavalent vaccine against botulism is in limited suppl

167 eus resulted in 16.7% and 91.7% mortality in pentavalent vaccine and control groups, respectively (P

168 In NHPs, a pentavalent vaccine candidate induced strong humoral and

169 A pentavalent vaccine combining all tested antigens protec

170 8-28 months) with 3 documented doses of the pentavalent vaccine delivered at central hospitals in Vi

171 Immunization with this pentavalent vaccine followed by intraperitoneal challeng

172 In developing a pentavalent vaccine for the prevention of GBS infections

173 If the pentavalent vaccine had been delivered during the CHDs i

174 h the planktonic and biofilm stages with the pentavalent vaccine or the IgG elicited by immunization

175 hat immunization of rhesus macaques with the pentavalent vaccine results in protection of 55% of pent

176 Completion of the pentavalent vaccine series was associated with 37% lower

177 n the safety and immunogenicity of NmCV-5, a pentavalent vaccine targeting the A, C, W, Y, and X sero

178 A pentavalent vaccine that also includes serogroup X (NmCV

179 onversion after routine vaccination with the pentavalent vaccine to capture weaknesses of vaccine man

180 Pentavalent vaccine was administered to those aged 6 wee

181 eneration rotavirus vaccines RotaTeq (RV5, a pentavalent vaccine) and Rotarix (RV1, a monovalent vacc

182 three doses of polio vaccine, three doses of pentavalent vaccine, and measles vaccine) by 12 months o

183 ased infection risk that are improved by the pentavalent vaccine.

184 eks who had not yet received a first dose of pentavalent vaccine.

185 lent vaccine results in protection of 55% of pentavalent-vaccine-immunized macaques from simian-human

186 lio 0 (birth-4 weeks), three polio and three pentavalent vaccines (4 weeks-2 months; 8 weeks-4 months

187 e assigned (1:1) to either a first dose of a pentavalent wP combination vaccine (DTwP-Hib-HepB, Penta