ライフサイエンスコーパス: peptidase inhibitor

1 a mechanism that was partially prevented by peptidase inhibitors.

2 indicates that it represents a new family of peptidase inhibitors.

3 behavioral and neurochemical effects of the peptidase inhibitors.

4 a subtractive strategy using class-specific peptidase inhibitors.

5 omain related to the Kunitz family of serine peptidase inhibitors.

6 We found that four splice variants of the peptidase inhibitor 16 (PI16) mRNA are among the most hi

7 The peptidase inhibitor 16 (PI16)-expressing reticular cell

8 CCL20, S100A7/A8/A9, DEFB4, lipocalin 2, and peptidase inhibitor 3 (p < 0.05), indicating a positive

9 Peptidase inhibitor 3 (PI3), a gene in the antimicrobial

10 kines (IL-12p40, IL-13, IL-22, CCL17, CCL18, peptidase inhibitor 3 [PI3]/elafin, and S100As) showed c

11 two negative control genes (cytochrome b and peptidase inhibitor 3) show no significant association.

12 (ie, IL-13, IL-22, CCL17, S100As, and elafin/peptidase inhibitor 3), and modulation of epidermal hype

13 imicrobials (IL-17A, IL-19, CCL20, LL37, and peptidase inhibitor 3/elafin), TH9/IL-9, IL-33, and inna

14 These findings indicate that NAAG peptidase inhibitors administered post-injury can signif

15 heters that were used to inject a mixture of peptidase inhibitors (amastatin, captopril and phosphora

16 ion in addition to 19 putative peptidases, 9 peptidase inhibitors and 7 C-type lectins that may funct

17 Serpins compose the largest superfamily of peptidase inhibitors and are well known as regulators of

18 nto differential distribution of peptidases, peptidase inhibitors and other potential allergenic prot

19 epE is not inhibited by any of the classical peptidase inhibitors, and its amino acid sequence does n

20 such as beta-lactam antibiotics, antivirals, peptidase inhibitors, and others as substrates.

21 ses and identified IL-1 cytokines and serine peptidase inhibitors as the most dysregulated esophagus-

22 ress several extracellular and intracellular peptidase inhibitors, as well as other molecules that ar

23 (Nqo1), peroxiredoxin-4 (Prdx4), and serine peptidase inhibitor b1b (Serpinb1b) and represses the ex

24 ced MOR-1 internalization in the presence of peptidase inhibitors, but little or no internalization i

25 ngs demonstrate that the application of NAAG peptidase inhibitors can reduce the deleterious motor an

26 tentially interdependent induction of serpin peptidase inhibitor, clade A member 3 (SERPINA3) and int

27 coding alpha-1 antitrypsin, SERPINA1 (serpin peptidase inhibitor, clade A, member 1), in determining

28 Cela1 was covalently bound to serpin peptidase inhibitor, clade A, member 1, resulting in a h

29 r studies indicate that serine (or cysteine) peptidase inhibitor, clade A, member 3N (SerpinA3N) may

30 Serine (or cysteine) peptidase inhibitor, clade A, member 3N (SerpinA3N), a s

31 mily member 1 (CLCA1), periostin, and serine peptidase inhibitor, clade B (ovalbumin), member 2 (serp

32 ride channel regulator 1 (CLCA1), and serpin peptidase inhibitor, clade B (SERPINB2).

33 bone morphogenic protein-2 and 4 and Serine peptidase inhibitor, clade E, member 1.

34 mutations were found in the SERPINF1 (Serpin Peptidase Inhibitor, Clade F) gene which encodes PEDF (p

35 8 (MTRNRL8), interleukin-8 (IL8), and serpin peptidase inhibitor, clade H (SERPINH1) and chemokine li

36 alin was doubled by application of all three peptidase inhibitors combined.

37 rally different HsPDF inhibitors and control peptidase inhibitors confirmed that inhibition of HsPDF

38 Attempts to base dd-peptidase inhibitor design on peptidoglycan structure, h

39 red on apolipoprotein E, jun, leptin, serpin peptidase inhibitor E type 1 and peroxisome proliferator

40 Used in combination with the cysteine peptidase inhibitor E-64, these substrates were able to

41 also differs from human in resisting tryptic peptidase inhibitors (e.g., aprotinin), while favoring a

42 in encoded by one of these genes, epididymal peptidase inhibitor (EPPIN), and associations found betw

43 ression of anti-inflammatory genes mainly of peptidase inhibitor families is upregulated in LL neutro

44 ntimicrobial peptide and secretory leukocyte peptidase inhibitor genes.

45 elevated expression of mucin-5B and several peptidase inhibitors, higher abundance of common commens

46 ue secretory signal peptide and a 90-residue peptidase inhibitor I9 domain in addition to the 283-res

47 es to show the involvement of peptidases and peptidase inhibitors in biological pathways have been cr

48 f small-molecule inhibitors in the tables of peptidase-inhibitor interactions, a table of known cleav

49 along with the known substrate cleavages and peptidase-inhibitor interactions, and a link to the KEGG

50 tion of known substrate cleavages; tables of peptidase-inhibitor interactions; and dynamically genera

51 o synthesize both enantiomers of an aspartic peptidase inhibitor intermediate, 3-hydroxy-4-phenylpipe

52 al microglia or adult microglia treated with peptidase inhibitors into spinal cord lesions of adult m

53 Each page shows the peptidases and peptidase inhibitors involved in the pathway, along with

54 or-knockout lines for the ecotin-like serine peptidase inhibitor (ISP2; Deltaisp2/isp3), an inhibitor

55 Missense mutations in the serine peptidase inhibitor Kazal type 5 (SPINK5) skin barrier g

56 itor (LEKTI), which is encoded by the serine peptidase inhibitor Kazal type 5 gene.

57 Serine peptidase inhibitor, Kazal type 1 (SPINK1) mRNA was very

58 In this study, we identified SPINT2 (serine peptidase inhibitor Kunitz type 2), a proteolytic inhibi

59 iation between low circulating plasma serine peptidase inhibitor Kunitz type-1 (SPINT1) concentration

60 lactate dehydrogenase B), and SPINT2 (serine peptidase inhibitor, Kunitz type 2) (all P < 0.001).

61 owing study, rats were administered the NAAG peptidase inhibitor PGI-02776 (10mg/kg) 30 min following

62 In the model, the zinc peptidase inhibitor, phosphoramidon, was docked in the a

63 Peptidase inhibitors (PIs) have been broadly studied due

64 on- and migration-related proteins including peptidase inhibitors, proteases, receptors, and integrin

65 ction/antimicrobial activity/detoxification, peptidase inhibitors, protein digestion (cysteine-, aspa

66 These peptidase inhibitors reduced the motor activation effect

67 Inhibition of the GCP II enzyme with NAAG peptidase inhibitors reduces the concentration of glutam

68 and have renamed lirL (prolipoprotein signal peptidase inhibitor resistance lipoprotein).

69 previously reported that secretory leukocyte peptidase inhibitor (SLPI) is regulated by the AR in a l

70 ike peptide 1 (GLP1) mimetics and dipeptidyl peptidase inhibitors that enhance GLP1 receptor activati

71 to elicit internalization were unaffected by peptidase inhibitors, the opioids released by veratridin

72 for enkephalin activity, we applied specific peptidase inhibitors to determine which peptidase(s) reg

73 inal cord slices while superfusing them with peptidase inhibitors to prevent opioid degradation.

74 oral effects and support the conclusion NAAG peptidase inhibitors warrant further study as a novel an

75 ty protein group B1 and serine (or cysteine) peptidase inhibitor were only enriched in the presence o

76 ence of cysteine and aspartic peptidases and peptidase inhibitors, whereas other peptidase families w

77 ly 180-kDa multidomain membrane-anchored pan-peptidase inhibitor, which is cleaved by host endopeptid

78 hat will help in the design of additional DD-peptidase inhibitors with the potential to serve as lead

79 gned di-ester prodrug of the urea-based NAAG peptidase inhibitor ZJ-43, was tested for neuroprotectiv

80 pothesis that two structurally distinct NAAG peptidase inhibitors, ZJ43 and 2-(phosphonomethyl)pentan