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1 expression of a betaarr1 C-terminal-derived peptide fragment.
2 hic secreted APPalpha (sAPPalpha) and the P3 peptide fragment.
3 d trypsin enzymes on NAA-NH(2) into the heme-peptide fragment.
4 ation may prevent the formation of cytotoxic peptide fragments.
5 nize the organismal origin of unknown DNA or peptide fragments.
6 in the hydrolysis of polypeptides into small peptide fragments.
7 ion NMR, and concomitant appearance of small peptide fragments.
8 ntimicrobial defense by clustering in active peptide fragments.
9 e of proIAPP in detail by analyzing a set of peptide fragments.
10 ent for intact proteins rather than degraded peptide fragments.
11 ire processing of native proteins into short peptide fragments.
12 hat is based on the coupling of glycopeptide/peptide fragments.
13 ro, staphopain B degraded LL-37 into shorter peptide fragments.
14 hod for the total synthesis of proteins from peptide fragments.
15 d comparative mass spectrometric analysis of peptide fragments.
16 leading to the formation of Abeta and Abeta peptide fragments.
17 ave studied the characteristics of these two peptide fragments.
18 erform native chemical ligation (NCL) of two peptide fragments.
19 ide bond formation between a large number of peptide fragments.
20 uently requires proteolysis of proteins into peptide fragments.
21 as obtained through N-terminal sequencing of peptide fragments.
22 ell as circulating N-terminal and C-terminal peptide fragments.
23 '-phosphorylated pentanucleotides containing peptide fragments.
24 ased upon single-stranded DNA scaffolding of peptide fragments.
25 only a few structures of oligomers formed by peptide fragments.
26 e semisynthesis via the chemical ligation of peptide fragments.
27 ti-apoptotic N1 and the scrapie-resistant C1 peptide fragments.
28 hat generate the pathogenic or nonpathogenic peptide fragments.
29 where it cleaves food proteins into smaller peptide fragments.
30 bn-N) and the TRAP (tyrosine-rich amelogenin peptide) fragments.
34 Synthesis and coupling of the individual peptide fragments [34 + 35 --> 51] followed by macrocycl
35 Preabsorption of the antiserum with metastin peptide fragment (45-54)-NH2 (1 microg/ml) resulted in n
36 um directed against the synthetic C-terminal peptide fragment (47-73), irBC was detected in the mouse
37 sing amino acid sequences derived from Csp24 peptide fragments, a full-length cDNA was cloned and sho
38 perature phase diagram for the amyloidogenic peptide fragment Abeta(16-22) Our results reveal that th
39 d chromatography fraction revealed two alpha-peptide fragments (alpha128-alpha139) and a heme moiety
40 ing of complex fragments, including a 20-mer peptide fragment analog of Exendin(9-39) on solid suppor
42 ng an efficient solid phase synthesis of the peptide fragment and an effective chemoenzymatic attachm
43 esulted in the cleavage of the MB containing peptide fragment and caused a decrease in electrical sig
45 d PKC-stimulated phosphorylation of the same peptide fragments and comigration of PKC-stimulated phos
47 corresponding to the carbohydrate-containing peptide fragments and large and small trypsin fragments
48 with MALDI-TOF mass spectrometry analysis of peptide fragments and peptide microsequencing, indicates
50 ences, native chemical ligation from smaller peptide fragments, and a high-throughput bacterial expre
51 sequence patterns, distinct from non-binding peptide fragments, and multi-millions of binding and non
52 -expressed T-cell receptors (TCRs) recognize peptide fragments (antigens) of pathogens bound to major
53 h analyses typically assume that a protein's peptide fragments are observed with equal likelihood, on
55 -isotope tags and fragmented, and the tagged peptide fragments are separated by liquid chromatography
56 s in the fluorescence intensity of a labeled peptide fragment as well as a decrease in solution pH as
59 mechanisms by which beta-amyloid (Abeta), a peptide fragment believed to contribute to Alzheimer's d
61 ld SPI forms large ions identified as common peptide fragments bound to either Fmoc or the surface li
62 effective in preliminary searches for C-PTH peptide fragments, but the use of high laser power limit
66 vealed that the CB1 C-terminal juxtamembrane peptide fragment CB1-(401-417) can directly activate the
67 nhardtii caltractin (CRC-C) and a 19 residue peptide fragment comprising the putative cdc31p-binding
68 ctional characteristics of template-directed peptide fragment condensation reactions in neutral aqueo
69 offer the promise of using this chemistry in peptide fragment condensations to produce modified pepti
71 receptor, while [ (125)I]IAC44 was found in peptide fragments consistent with labeling of both SBDLI
74 in its amino acid sequence and that a TcSSS peptide fragment containing a sequence homologous to a b
75 and RGS16 incorporated [3H]palmitate into a peptide fragment containing Cys-98, a highly conserved c
78 o signal, whereas the enzymatically produced peptide fragment containing the above sequence showed th
81 718 and 1831, corresponding to the unlabeled peptide fragments containing the active site Tyr411 resi
82 fibrils are built by modifying the synthetic peptide fragment corresponding to residues 105-115 of th
83 tion of vectors that drive the expression of peptide fragments corresponding to their binding domains
84 cortactin Src homology 3 (SH3) domain with a peptide fragment derived from a cDNA encoding a region o
86 tal surface with REDOR NMR show that, in the peptide fragment derived from the N-terminal 15 amino ac
87 ative cysteine with a succinimide group in a peptide fragment derived from thioredoxin-1 (Trx-1) obta
88 f high-resolution structures of CaM bound to peptide fragments derived from ion channels, there is no
92 ancing activity parallels the degradation of peptide fragments derived from the semenogelins (SEMs),
93 the Ru label, whereas binding of the cleaved peptide fragment devoid of Ru label reduced the ECL sign
95 L) method that enables efficient ligation of peptide fragments down to low nanomolar concentrations,
97 measure the molecular weights of the tryptic peptide fragments (e.g., peptide mass mapping) and parti
98 rabbit antiserum raised against a synthetic peptide fragment encoding the unique C terminus revealed
99 ing the Rosetta fragment picker for accurate peptide fragment ensemble generation, the PIPER docking
100 uence patterns between intra-protein binding peptide fragments exist, they can be extracted using a d
101 the peptide mass fingerprint (MALDI-TOF) and peptide fragment fingerprinting (MALDI LIFT-TOF/TOF) spe
104 on these regions, we focused on an antigenic peptide fragment from a disulfide bridge-bounded region
107 anic molecule (fluorescein), a 12 amino acid peptide fragment from the C-terminus of beta-catenin, th
110 xpensive methodology to generate fluorescent peptide fragments from a parent sequence with diverse ch
111 toreceptor retinoid-binding protein dose and peptide fragments from conventional experimental autoimm
112 nd multi-millions of binding and non-binding peptide fragments from currently available protein X-ray
113 tration calorimetry to investigate synthetic peptide fragments from different domains of the full-len
122 peptide (2.5HIP) consisting of an insulin C-peptide fragment fused to a peptide from chromogranin A
123 proteins and/or an LC-MS analysis of tryptic peptide fragments generated after the oxidation reaction
125 taL-crystallin was higher in the presence of peptide fragments generated from oxidized and trypsin-di
128 erefore been necessary, for instance, on the peptide fragment GNNQQNY7-13 of yeast prion protein Sup3
130 l crystal structures of skeletal muscle RyR1 peptide fragments have been solved, but these cover less
133 with CD and 1D NMR studies of the 21-residue peptide fragment (HP21) derived from HP36 have shown tha
134 s work, for the first time, four human C-PTH peptide fragments, hPTH(34-84), hPTH(37-84), hPTH(38-84)
137 oth cell types, and amino acid sequencing of peptide fragments identified the same protein, histone H
138 antibodies against GB-generated centromeric peptide fragments identify a distinct clinical subset.
139 hat inhibit the recruitment of a coactivator peptide fragment in in vitro biochemical assays (IC(50)
141 signature for identifying inhibitor-modified peptide fragments in complex mass spectrometry data.
142 showed that the distribution patterns of the peptide fragments in Gl-L and Gd-L were similar, but mor
146 , we identified over one dozen APP-generated peptide fragments in wild-type yeast (PRE1PRE2) and over
148 on program, it was observed that some cyclic peptides fragmented in unexpected ways resulting in the
149 eave chromogranin A into biologically active peptide fragments, including catestatin, which inhibits
151 ry/mass spectrometry analysis on the tryptic peptide fragments indicates that the 3-fluorosialyl moie
152 reached by using only seven short synthetic peptide fragments, instead of the 155 non-overlapping 15
154 ecursors, presentation requires transport of peptide fragments into the ER, but the nature of the cyt
155 site-specific integration of amino acids and peptide fragments into the homodetic cyclic peptide arch
157 ed by a diagnostic mass shift in one or more peptide fragment ions (for example, phosphorylation).
160 aining reagents for shifting mass defects of peptide fragment ions was systematically investigated, t
161 The ASA method successfully distinguishes peptide fragment ions with and without an FIMDL group an
163 ctra included singly protonated peptide ion, peptide fragment ions, and peaks characteristic of the s
164 dentification of these separated proteins or peptide fragments is typically achieved by mass spectrom
166 ce with the mixed GAG glycosylation of agrin peptide fragments, it was found that recombinant and in
167 e (TDP1) is a DNA repair enzyme that removes peptide fragments linked through tyrosine to the 3' end
168 type glycopeptide fraction revealed Asn-732 peptide fragments linked to the sulfoquinovose-containin
169 that exist in vertebrates, presenting small peptide fragments, lipid molecules, or small molecule me
171 for DnaK, examined via a short 13-mer apoMb peptide fragment matching the binding site sequence, dis
172 f spermatogenesis suggests that this laminin peptide fragment may serve as a contraceptive in male ra
174 inally, intracellular application of the MIF peptide fragment MIF-(50-65), which harbors the thiol ox
175 he biotinylated peptides and analysis of the peptide fragment mixture by nanospray liquid chromatogra
176 sis of the pepsin-induced fibrils implicates peptide fragments (named H) consisting of the 13 or 15 N
179 gen-associated molecular patterns, including peptide fragment of bacterial flagellin (flg22) or trans
181 Using in vitro systems, we have identified a peptide fragment of gankyrin, 176LHLACDEERN185, which is
183 reatment of MeCP2 mutant mice with an active peptide fragment of Insulin-like Growth Factor 1 (IGF-1)
184 as reinhardtii centrin for calcium and for a peptide fragment of Kar1p using CD, fluorescence, and NM
185 that the binding mode and stoichiometry of a peptide fragment of NDR (NDR(62-87)) is the same as for
186 location of PPAR-gamma is blocked by a short peptide fragment of NOC that inhibits its physical inter
189 I), an amyloid fibril formed from a cationic peptide fragment of prostatic acidic phosphatase (PAP),
192 we report the high-resolution structure of a peptide fragment of the amyloidogenic protein transthyre
199 assessed whether administration of a soluble peptide fragment of the NgR (sNgR) that binds to and blo
200 myloid fibrils formed from a self-assembling peptide fragment of the protein prostatic acid phosphata
203 d VEGF-A binding in the NRP1 b1 domain and a peptide fragment of VEGF-A was shown to bind at the same
205 of DCs to internalize, degrade, and express peptide fragments of antigenic proteins on their surface
206 s were substantially inhibited by N-terminal peptide fragments of Anxa2 or anti-Anxa2 antibodies.
208 uence curvature sensing and explores whether peptide fragments of even shorter length can function as
212 pansion, followed by exposure to overlapping peptide fragments of PE38 and an IL-2 ELISpot assay to m
213 cyte Antigen (HLA) Class I molecules bind to peptide fragments of proteins degraded inside the cell a
214 ificant reactions of the monochloramine with peptide fragments of proteins that are associated with c
215 gators have therefore preferred to work with peptide fragments of PrP, suggesting that these peptides
216 ficity of otherwise poorly active N-terminal peptide fragments of PTH by conjugating them to nanobodi
217 betic (NOD) mice, repeated administration of peptide fragments of target antigens in incomplete Freun
218 ionization mass spectrometry identified two peptide fragments of the alphaB crystallin Walker-B moti
219 posits of insoluble, fibrillar aggregates of peptide fragments of the amyloid precursor protein (APP)
221 Previous studies have shown that synthetic peptide fragments of the PrP sequence corresponding to r
224 the modified ubiquitin and isomeric glycated peptides (fragments of bovine serum albumin (BSA)).
225 on, expression of a dominant negative mutant peptide fragment or injection of a function-blocking ant
226 allows the controlled production of typical peptide fragments or elemental reporter ions informing a
227 gamma-chains of fibrin and the appearance of peptide fragments over time were assessed by polyacrylam
228 he CD8(+) T-cell surface interact with short peptide fragments (p) bound to MHC class I molecules (pM
232 Full-length and conserved C-terminal delta peptide fragments permeabilize the plasma membranes of n
235 udy, we provide evidence that the C-terminal peptide fragment produced by caspase cleavage inhibits t
236 Low molecular weight protamine (LMWP) is a peptide fragment produced in our laboratory from enzymat
238 scopic and mass spectrometric studies of the peptide fragments resulting from tryptic digestion of Ka
239 nce liquid chromatographic separation of the peptide fragments resulting from tryptic digestion of re
240 and structure of microbial communities using peptide fragment sequences extracted from metagenomic se
242 em, it is generally assumed that angiotensin peptide fragments shorter than angiotensins II and III,
243 ts on the full alphatalpha motif and its two peptide fragments show that interhelical tertiary contac
244 ons followed by MALDI-TOF MS analysis of the peptide fragments showed these 47 kDa species to be CRP
246 e species include full-length SOD1 proteins, peptide fragments, stable oligomers and ubiquitinated en
247 ) NMR study of the fibrils formed by a small peptide fragment, structural details of beta(2)m fibrils
248 tive did not identify any covalently labeled peptide fragments, suggesting that the phenylazido side
249 ansfected HEK-293 cells revealed that a CFTR peptide fragment that binds AMPK (CFTR-1420-57) disrupte
250 an be used as a template to design a minimal peptide fragment that can be used as a drug against Rho-
252 e the solution structure of the Abeta(21-30) peptide fragment that may be relevant for understanding
254 otease digestion of the complex, generated a peptide fragment that was bound to the SG promoter.
255 ty of SagA is required and generates muramyl-peptide fragments that are sufficient to protect C. eleg
256 oach involves the digestion of proteins into peptide fragments that can be detected and sequenced wit
257 radation, inflammation and invasion liberate peptide fragments that can subsequently interact with ce
258 th or without CKI-alpha depletion identified peptide fragments that corresponded to the region locate
259 osurvival signaling or generate proapoptotic peptide fragments that help to execute the death program
261 arboxyl-terminal parathyroid hormone (C-PTH) peptide fragments that may be present at only picomolar
262 acquisition of approximately 100 overlapping peptide fragments that redundantly cover the 243-residue
263 that barnase can be split into two inactive peptide fragments, that when co-expressed can complement
264 the C-terminal acyl donor and using smaller peptide fragments, the Cys(29)-Gly(77) glycopeptide doma
265 derived from automatic Edman degradation of peptide fragments, the SmCI sequence was fully character
266 Alanine ligation was used to assemble four peptide fragments, themselves prepared by solid phase pe
268 are generally characterized through tryptic peptide fragments, this paper reports a method for the i
269 ies via the deactivation of the SrtA-excised peptide fragment through diketopiperazine (DKP) formatio
270 ble to effectively stabilize the problematic peptide fragment through the attachment of cleavable arg
271 omochiral products from a racemic mixture of peptide fragments through a chiroselective autocatalytic
272 acyl-enzyme intermediate linking one of the peptide fragment to a catalytic subunit of the proteasom
273 MyBP-C (cMyBP-C), we added human N-terminal peptide fragments to human and rodent skinned ventricula
275 ex with the human receptor and a coactivator peptide fragment using x-ray crystallography at 1.9-A re
279 increase in the relative intensities of the peptide fragments was achieved, which led to the identif
281 aterial throughput and convergency, the five peptide fragments were assembled into the native ATAD2 b
282 ch protein digest and the number of detected peptide fragments were compared with conventional MALDI
283 the peptide bonds of BSA were hydrolyzed and peptide fragments were desorbed from the surface of gold
286 ll-length Gag-p24 protein, and the resulting peptide fragments were identified by mass spectrometry.
287 ng MALDI-TOF MS, and 102 out of 153 possible peptide fragments were identified giving a sequence cove
288 digested with chymotrypsin, and the modified peptide fragments were isolated and characterized as 6-h
290 ed caspase-3 in vitro, 13- and 17-kDa capsid peptide fragments were observed and were predicted by al
291 th trypsin and endoproteinase Asp-N, and the peptide fragments were purified by high performance liqu
292 le GFAP- and MBP-immunoreactive proteins and peptide fragments were seen, and many of them were also
294 istinct proteasomal degradation patterns and peptide fragments were unique to either mature DC or act
296 ) is a naturally occurring 40- or 42-residue peptide fragment with a primary role in Alzheimer's dise
298 omic sequence collections revealed groups of peptide fragments with a relatively high abundance and n
300 driven dissociation because glycan-retaining peptide fragments would not be required for localization