ライフサイエンスコーパス: peptide nucleic acid

1 nto oligomeric strands that are analogous to peptide nucleic acid.

2 -(2-aminoethyl)glycine (AEG), a backbone for peptide nucleic acids.

3 very of conventional and chemically-modified peptides nucleic acids.

4 sed by reduction in the cytoplasm, including peptide nucleic acids, a cyclic peptide (phalloidin), an

5 mobilized anthraquinone-labeled pyrrolidinyl peptide nucleic acid (acpcPNA) probe was successfully de

6 ection system using immobilized pyrrolidinyl peptide nucleic acid (acpcPNA) probes.

7 ssay for DNA detection based on pyrrolidinyl peptide nucleic acid (acpcPNA)-induced nanoparticle aggr

8 sensor was developed based on a pyrrolidinyl peptide nucleic acid (acpcPNA)/polypyrrole (PPy)/silver

9 ethylenediamine portion of aminoethylglycine peptide nucleic acids (aegPNAs) with one or more (S,S)-t

10 We have shown that antigene peptide nucleic acids (agPNAs) and antigene duplex RNAs

11 The resulting alpha-helical peptide nucleic acids (alpha PNAs) are composed of a rep

12 Peptide nucleic acid and 2'-O-MeRNA oligomers inhibit te

13 We report that peptide nucleic acid and locked nucleic acid antisense o

14 Here we use triplex-forming peptide nucleic acids and donor DNA in biodegradable pol

15 itions adjacent to the lambda operators with peptide nucleic acids and monitored their movement by te

16 here is a brief introduction to the field of peptide nucleic acids and their potential benefits as pr

17 y method is described based on surface-bound peptide nucleic acids and water-soluble cationic conjuga

18 More specifically, proteins, peptides, nucleic acids and polysaccharides serve as vit

19 made with triplex-forming oligonucleotides, peptide nucleic acids, and polyamides, but substantial e

20 biomimetics, molecular imprinting polymers, peptide nucleic acids, and ribozymes were encompassed as

21 ProtCID to the interactions of domains with peptides, nucleic acids, and ligands.

22 miR-690 knockdown using peptide nucleic acid-antagomiR was able to unblock and s

23 ments using two triplex-forming molecules, a peptide nucleic acid-antennapedia (PNA-Antp), and a TFO

24 We find that the attachment of peptide nucleic acid antimiRs to a peptide with a low pH

25 Peptide nucleic acids are a class of nondegradable oligo

26 Finally recent results on the use of peptide nucleic acids as oligonucleotides surrogate are

27 The platform was developed using peptide nucleic acids as probes on gold electrode surfac

28 Herein, we show that peptide nucleic acids, as short as six nucleobases, bind

29 s, stemless and stem-containing DNA and PNA (peptide nucleic acid) beacons, in Tris-buffer solutions

30 Bis-peptide nucleic acid (bis-PNA) binding results in D-loop

31 Calpha-bimodal peptide nucleic acids (bm-Calpha-PNA) are PNAs with two

32 emplated chemical transformation of bifacial peptide nucleic acid (bPNA) fragments directed by an abi

33 We demonstrate herein that bifacial peptide nucleic acid (bPNA) hybrid triplexes functionall

34 operties of bPNA+, a new variant of bifacial peptide nucleic acid (bPNA) that binds oligo T/U nucleic

35 tative NMR spectral parameters for proteins, peptides, nucleic acids, carbohydrates and ligands or co

36 cally labeled using a fluorescein-conjugated peptide nucleic acid clamp.

37 hanism and kinetic specificity of binding of peptide nucleic acid clamps (bis-PNAs) to double-strande

38 Peptide nucleic acids containing thymidine and 2-aminopy

39 ces, followed by highlights of ways by which peptide nucleic acids could benefit a number of establis

40 The T414G mutation was analyzed by peptide nucleic acid directed clamping PCR.

41 The activity of the peptide nucleic acids does not involve inhibition of tra

42 We show that systemic delivery of antisense peptide nucleic acids encapsulated in unique polymer nan

43 ever, "ligand" molecules, included proteins, peptides, nucleic acids, etc. are expensive and vulnerab

44 diffusivity between a free ferrocene-labeled peptide nucleic acid (Fc-PNA) and a Fc-PNA hybridized wi

45 ates or anti-GFP nanobodies, interfaced with peptide nucleic acids, flipper force probes, or fluoresc

46 A novel rapid peptide nucleic acid fluorescence in situ hybridization

47 Peptide nucleic acid fluorescence in situ hybridization

48 valuate the performance of a new three-color peptide nucleic acid fluorescence in situ hybridization

49 A shortened protocol for two peptide nucleic acid fluorescence in situ hybridization

50 The utility of peptide nucleic acid fluorescence in situ hybridization

51 These newer tests, peptide nucleic acid fluorescence in situ hybridization

52 carensis and C. nivariensis species-specific peptide nucleic acid fluorescence in situ hybridization

53 cation of Candida albicans blood isolates by peptide nucleic acid fluorescence in situ hybridization

54 in blood culture bottles within 2.5 h using peptide nucleic acid fluorescence in situ hybridization.

55 We investigated a 2.5-h peptide nucleic acid-fluorescence in situ hybridization

56 A blinded comparison of peptide nucleic acid-fluorescence in situ hybridization

57 In this work, two 28S rRNA-directed peptide nucleic acid-fluorescence in situ hybridization

58 ichment broths by the use of subculture, GBS peptide nucleic acid fluorescent in situ hybridization (

59 selective Streptococcus agar (SSA), and by a peptide nucleic acid fluorescent in situ hybridization (

60 nce of the Candida albicans/Candida glabrata peptide nucleic acid fluorescent in situ hybridization (

61 on of a biofilm in vivo was visualized using peptide nucleic acid fluorescent in situ hybridization (

62 ch probes could be used as an alternative to peptide nucleic acids for investigating the dynamics of

63 mides, triplex-forming oligonucleotides, and peptide nucleic acids for recognition of chromosomal DNA

64 ntly, we have considered the use of DNAs and peptide nucleic acids for this purpose because oligomers

65 how that conformationally preorganized gamma-peptide nucleic acid (gamma-PNA) containing an acridine

66 opipette and an assay of complementary gamma-peptide nucleic acid (gamma-PNA) probes conjugated to po

67 eparing optically pure guanidine-based gamma-peptide nucleic acid (gammaGPNA) monomers for all four n

68 the mRNA and a complementary gamma-modified peptide nucleic acid (gammaPNA) sequence with a noncompl

69 Here we demonstrate that gamma-modified peptide nucleic acids (gammaPNA) can be used to enable f

70 Over the past three decades, peptide nucleic acids have been employed in numerous che

71 Guanine-rich peptide nucleic acids have been previously shown to hybr

72 thymine [2+2] dimer repair in DNA and in DNA/peptide nucleic acid hybrid duplexes.

73 othiadiazole) dibromide]), and neutral PNA (peptide nucleic acid) hybridization probes.

74 ansfer (FRET) between fluorescently labelled peptide nucleic acids, hybridized to defined single stra

75 midate (MO) 20mer or hydroxyprolyl-phosphono peptide nucleic acid (HypNA-pPNA) 16mer antisense oligon

76 Oligonucleotides, peptides, and peptide nucleic acids incorporating 7-oxanorbornene as a

77 tment of established PNFs using anti-miR-155 peptide nucleic acid-loaded nanoparticles marginally dec

78 eukaryotic histones, synthetic peptides, or peptide nucleic acids may be limited by high production

79 Before RNA-based organisms arose, peptide nucleic acids may have been used to transmit gen

80 The peptide nucleic acid-mediated 5 nuclease real-time polym

81 from 97 baseline blood samples by our novel peptide nucleic acid-mediated 5 nuclease real-time polym

82 rference with these lncRNAs using complement peptide nucleic acid molecules down-regulated the active

83 can be successfully targeted by an antisense peptide nucleic acid oligomer named PNA(PR2).

84 Peptide nucleic acid oligomers (PNAs) have a remarkable

85 sequences are superior to those of analogous peptide nucleic acid oligomers, emphasizing the value of

86 ring probe) is threaded, with the aid of two peptide nucleic acid openers, between the two strands of

87 nucleotide, its analog or its mimic (such as peptide nucleic acid, or PNA).

88 e, we report the use of pseudo-complementary peptide nucleic acids (pcPNAs) for intracellular gene ta

89 aluates the potential of pseudocomplementary peptide nucleic acids (pcPNAs) for sequence-specific mod

90 ere, we demonstrate that pseudocomplementary peptide nucleic acids (pcPNAs) represent a class of vers

91 utations in AS, we developed allele-specific peptide nucleic acid-PCR assays.

92 ore stably bound to plasmid DNA than similar peptide nucleic acid (PNA) 'clamps' for procedures such

93 nce-specific DNA-templated polymerization of peptide nucleic acid (PNA) aldehydes.

94 Poly(A) DNA, RNA and peptide nucleic acid (PNA) all form these assemblies.

95 etrating peptide (CPP) conjugates of a 16mer peptide nucleic acid (PNA) analogue targeted to the apic

96 lly cationic and chiral C(gamma)-substituted peptide nucleic acid (PNA) analogues have been synthesiz

97 Here, we test the hypothesis that antisense peptide nucleic acid (PNA) and locked nucleic acid (LNA)

98 based on the strand replacement of dsDNA by peptide nucleic acid (PNA) and the in situ growth of ele

99 G12D and ~100-fold increased sensitivity of Peptide Nucleic Acid (PNA) and Xenonucleic Acid (XNA) cl

100 systemic barriers for in vivo application of peptide nucleic acid (PNA) anti-microRNA therapeutics.

101 We showed previously that peptide nucleic acid (PNA) anti-miRs containing a few at

102 sociated CD40 protein expression by use of a peptide nucleic acid (PNA) antisense inhibitor, ISIS 208

103 n charge transfer in double-stranded DNA and peptide nucleic acid (PNA) are investigated.

104 ly and sequence-specifically to pDNA using a peptide nucleic acid (PNA) as a linker molecule.

105 Peptide nucleic acid (PNA) as a novel DNA-binding reagen

106 engineered with a novel and highly specific peptide nucleic acid (PNA) as the recognition element.

107 (2'-O-MOE) phosphorothioate, morpholino and peptide nucleic acid (PNA) backbones was investigated us

108 The second one starts from peptide nucleic acid (PNA) building blocks in which nucl

109 Peptide nucleic acid (PNA) building blocks, bearing a fl

110 ivities of a cell-permeable, guanidine-based peptide nucleic acid (PNA) called GPNA.

111 lo domain partitioning of the palmitoylated peptide nucleic acid (PNA) can be influenced by formatio

112 Here we demonstrate how peptide nucleic acid (PNA) can be used to control the as

113 a gold electrode coated with charge neutral peptide nucleic acid (PNA) capture probes (CPs) is first

114 itoneal injection of an unmodified antisense peptide nucleic acid (PNA) complementary to mRNA of the

115 opolymer microgel based on protein, DNA, and peptide nucleic acid (PNA) components.

116 id fluorenylmethyloxycarbonyl (Fmoc)-guanine peptide nucleic acid (PNA) conjugate with diverse morpho

117 ense imaging agent comprised of an iodinated peptide nucleic acid (PNA) conjugated to a monoclonal an

118 sonant mechanism of charge transfer in short peptide nucleic acid (PNA) duplexes obtained through ele

119 hroughput microarray screening process using peptide nucleic acid (PNA) encoding technology, allowing

120 e tube coagulase test (TCT) read at 4 h, and peptide nucleic acid (PNA) fluorescence in situ hybridiz

121 easts on Gram stain using a Candida albicans peptide nucleic acid (PNA) fluorescent in situ hybridiza

122 U) for the synthesis of pseudo-complementary peptide nucleic acid (PNA) has been evaluated.

123 "reporter and miRNA" and "reporter and miRNA-peptide nucleic acid (PNA) hybrid", which yields two sig

124 esized that scintigraphic detection of CCND1 peptide nucleic acid (PNA) hybridization probes with a (

125 ations, using allele-specific, mass-labeled, peptide nucleic acid (PNA) hybridization probes, and dir

126 t can suit CE-based miRNA analysis utilizing peptide nucleic acid (PNA) hybridization probes.

127 We designed a CCND1-specific peptide nucleic acid (PNA) hybridization sequence (CTGGT

128 the zein gene from maize using pyrrolidinyl peptide nucleic acid (PNA) immobilized on a magnetic sol

129 ng RNA function in living cells that we call peptide nucleic acid (PNA) interference mapping.

130 Peptide nucleic acid (PNA) is a DNA mimic in which the n

131 Peptide nucleic acid (PNA) is a DNA mimic with improved

132 Peptide nucleic acid (PNA) is a DNA/RNA mimic that offer

133 Peptide nucleic acid (PNA) is a promising precursor to R

134 Peptide nucleic acid (PNA) is a synthetic analogue of DN

135 Peptide nucleic acid (PNA) is a synthetic DNA mimic with

136 Peptide nucleic acid (PNA) is a synthetic mimic of DNA a

137 s of molecular dynamics simulations of small peptide nucleic acid (PNA) molecules, synthetic analogs

138 uration of the target plasmid sample using a peptide nucleic acid (PNA) oligomer as the probe is desc

139 A peptide nucleic acid (PNA) oligomer, an analogue of DNA,

140 Peptide nucleic acid (PNA) oligomerization of the 5,6-be

141 nes in two mutually complementary mixed-base peptide nucleic acid (PNA) oligomers are substituted wit

142 Guanine-rich peptide nucleic acid (PNA) oligomers bind to homologous

143 Snap-to-it probes were prepared from peptide nucleic acid (PNA) oligomers by modifying each t

144 Peptide nucleic acid (PNA) oligomers targeted to guanine

145 A series of partially self-complementary peptide nucleic acid (PNA) oligomers was prepared.

146 ere, we show that a short antisense chimeric peptide nucleic acid (PNA) oligonucleotide conjugated to

147 Steric blocking peptide nucleic acid (PNA) oligonucleotides have been us

148 led telomeric repeat complementing (CCCTAA)3 peptide nucleic acid (PNA) probe coupled with cardiac-sp

149 va telomeric sequence d(G(4)T(4)G(4)) with a peptide nucleic acid (PNA) probe having a homologous rat

150 iameter polystyrene beads to which uncharged peptide nucleic acid (PNA) probe molecules have been con

151 cribed were internally functionalized with a peptide nucleic acid (PNA) probe specific for a gene tra

152 ry after labeling with an S. aureus-specific peptide nucleic acid (PNA) probe.

153 of a target genomic DNA and a complementary peptide nucleic acid (PNA) probe.

154 n situ hybridization (FISH) method that uses peptide nucleic acid (PNA) probes for identification of

155 nce in situ hybridization (FISH) method with peptide nucleic acid (PNA) probes for identification of

156 Peptide nucleic acid (PNA) probes have been synthesized

157 report demonstrates the use of high-affinity peptide nucleic acid (PNA) probes in labeling mRNA trans

158 Comparison with published data for DNA and peptide nucleic acid (PNA) probes is carried out to look

159 Peptide nucleic acid (PNA) probes targeting APP, combine

160 orescence in situ hybridization (FISH) using peptide nucleic acid (PNA) probes targeting Staphylococc

161 Briefly, thiolated peptide nucleic acid (PNA) probes were firstly immobiliz

162 Peptide nucleic acid (PNA) probes were used to capture R

163 on by using cationic conjugated polymers and peptide nucleic acid (PNA) probes with ultrafast pump-du

164 A strategy employing a combination of peptide nucleic acid (PNA) probes, an optically amplifyi

165 nologies: rapid cycling PCR thermal cyclers, peptide nucleic acid (PNA) probes, and a new double-stra

166 zation biosensor, based on thiol-derivatized peptide nucleic acid (PNA) probes, offers unusual in sit

167 acid and nucleobase sequences into a single peptide nucleic acid (PNA) scaffold to enable tunable st

168 ochemically active molecular probes based on peptide nucleic acid (PNA) scaffolds for the detection o

169 as synthetic threose nucleic acid (TNA) and peptide nucleic acid (PNA) scaffolds.

170 ensitize the emission of a dye on a specific peptide nucleic acid (PNA) sequence for the purpose of h

171 b-on-PCB DNA diagnostic platform, exploiting peptide nucleic acid (PNA) sequences as probes.

172 A peptide nucleic acid (PNA) targeting a splice junction o

173 ted nucleosome within the polymer by using a peptide nucleic acid (PNA) targeting compound.

174 mycin B (ring II) was conjugated to a 16-mer peptide nucleic acid (PNA) targeting HIV-1 TAR RNA.

175 ew DNA diagnostic is based on combination of peptide nucleic acid (PNA) technology, rolling circle am

176 tic approach to develop an embedded chimeric peptide nucleic acid (PNA) that effectively enters the c

177 nt studies describe the production of 16-mer peptide nucleic acid (PNA) that is antisense around the

178 n 3D nucleic acid-amino acid complexes using peptide nucleic acid (PNA) to assemble peptides inside a

179 Using a peptide nucleic acid (PNA) trap assay, we show that G4R1

180 e energy transfer (FRET) measurements with a peptide nucleic acid (PNA) trap.

181 Briefly, mercapto-terminated peptide nucleic acid (PNA) was firstly immobilized onto

182 A modified M918 peptide conjugated to a peptide nucleic acid (PNA) was shown to silence lucifera

183 The modification of peptide nucleic acid (PNA) with unnatural nucleobases en

184 We show here that the hybridization of a peptide nucleic acid (PNA) within or adjacent to the pro

185 To address this issue, we tested peptide nucleic acid (PNA), chemically modified RNA and

186 C locked nucleic acid (LNA) residues, and a peptide nucleic acid (PNA), inhibit Tat-dependent in vit

187 molecules, each linked to a short strand of peptide nucleic acid (PNA), synthetic polymers that use

188 o acid is used as a building block for a new peptide nucleic acid (PNA), which exhibits excellent DNA

189 A bis-peptide nucleic acid (PNA)-anthraquinone imide (AQI) con

190 Using the recently developed peptide nucleic acid (PNA)-assisted assay, which makes i

191 The peptide nucleic acid (PNA)-assisted identification of RB

192 We have developed the peptide nucleic acid (PNA)-assisted identification of RB

193 We report on the peptide nucleic acid (PNA)-directed design of a DNA-nick

194 DNA samples are first amplified using peptide nucleic acid (PNA)-directed PCR clamping reactio

195 The peptide nucleic acid (PNA)-directed PCR clamping techniq

196 teraction between a cationic cyanine dye and peptide nucleic acid (PNA)-DNA duplexes.

197 was to synthesize and evaluate radiolabeled peptide nucleic acid (PNA)-peptide conjugates targeting

198 We describe the synthesis of peptide nucleic acid (PNA)-titanium dioxide (TiO(2)) nan

199 ividual bases are added to abasic sites of a peptide nucleic acid (PNA).

200 her self-folding polymers, including DNA and peptide nucleic acid (PNA).

201 ch the 15mer DNA was replaced by a strand of peptide nucleic acid (PNA).

202 displaced strand with a nucleic acid mimic, peptide nucleic acid (PNA).

203 rves as a trap was replaced with a strand of peptide nucleic acid (PNA).

204 mbled with the aid of a DNA synthetic mimic, peptide nucleic acid (PNA).

205 screening with less flexible, self-assembled peptide nucleic acid (PNA).DNA complexes uncovered a wel

206 An approach is described for predicting peptide nucleic acid (PNA):DNA duplex stability from bas

207 ying lengths by hybridization of n-alkylated peptide nucleic acids (PNA amphiphiles) to the products,

208 Peptide nucleic acids (PNA) are mimics with normal bases

209 d whether tunable-surface bead chemistry and peptide nucleic acids (PNA) could enhance the recovery a

210 Peptide nucleic acids (PNA) mimic DNA and RNA by forming

211 The discovery that peptide nucleic acids (PNA) mimic DNA and RNA by forming

212 The ability of peptide nucleic acids (PNA) to form specific higher-orde

213 logues, which also include compounds such as peptide nucleic acids (PNA), in surface hybridization ap

214 Utilizing the neutral backbone of peptide nucleic acids (PNA), our method is based on the

215 Toward such applications using peptide nucleic acids (PNA), we herein report the chemic

216 In the current study, we describe a peptide nucleic acids (PNA)-based approach to block the

217 Here we show that ssODNs made of peptide nucleic acids (PNA-ssODNs) can achieve gene repa

218 rrelating with gene knockdown, we employed a peptide-nucleic acid (PNA) hybridization assay.

219 obes: anneal-inhibiting blocking primers and peptide-nucleic acid (PNA) oligonucleotide blockers.

220 equently, molecularly-imprinted polymers and Peptide nucleic acid (PNAs) were developed as an attract

221 is based on two ligands functionalized with peptide nucleic acids (PNAs) (templating strand and cata

222 the field - locked nucleic acids (LNAs) and peptide nucleic acids (PNAs) - significantly increase th

223 Here, we show that antisense peptide nucleic acids (PNAs) alter splicing of the IL-5R

224 Peptide nucleic acids (PNAs) are a DNA mimic in which th

225 Peptide nucleic acids (PNAs) are a potentially powerful

226 Peptide nucleic acids (PNAs) are a powerful tool for rec

227 Peptide nucleic acids (PNAs) are analogs of nucleic acid

228 Compared to DNA and RNA, peptide nucleic acids (PNAs) are chemically stable and h

229 lamide (HPMA) polymers grafted with multiple peptide nucleic acids (PNAs) are crosslinked upon additi

230 Peptide nucleic acids (PNAs) are DNA analogs containing

231 Peptide nucleic acids (PNAs) are DNA analogs that bind w

232 Peptide nucleic acids (PNAs) are engineered uncharged ol

233 Peptide nucleic acids (PNAs) are linear equivalents of D

234 Although peptide nucleic acids (PNAs) are neutral by themselves,

235 Peptide nucleic acids (PNAs) are nonionic DNA/RNA mimics

236 Peptide nucleic acids (PNAs) are uncharged analogs of DN

237 es for a successful and broad application of peptide nucleic acids (PNAs) as antisense therapeutics.

238 eport the development of chemically modified peptide nucleic acids (PNAs) as probes for qualitative a

239 Peptide nucleic acids (PNAs) can bind to homopurine/homo

240 Peptide nucleic acids (PNAs) can bind to single-stranded

241 assembled monolayers of single-stranded (ss) peptide nucleic acids (PNAs) containing seven nucleotide

242 Here, we show that peptide nucleic acids (PNAs) efficiently block a key ind

243 Peptide nucleic acids (PNAs) have also been extensively

244 Gold nanocrystals modified with peptide nucleic acids (PNAs) have been prepared and appl

245 forming oligonucleotides and triplex-forming peptide nucleic acids (PNAs) have been shown to stimulat

246 plex-forming DNA oligonucleotides (TFOs) and peptide nucleic acids (PNAs) have been shown to stimulat

247 Peptide nucleic acids (PNAs) have stronger affinity and

248 To determine the effectiveness of peptide nucleic acids (PNAs) in vivo, we designed and sy

249 verning the inhibition of gene expression by peptide nucleic acids (PNAs) inside cells.

250 st attempt to overcome this problem by using peptide nucleic acids (PNAs) modified with extended nucl

251 Peptide nucleic acids (PNAs) offer a distinct option for

252 Peptide nucleic acids (PNAs) present a novel method to t

253 Here we report that triplex-forming peptide nucleic acids (PNAs) substituted at the gamma po

254 e imaged in a mouse by PET with 64Cu-labeled Peptide nucleic acids (PNAs) tethered to the permeation

255 induce G-quadruplex formation, we used short peptide nucleic acids (PNAs) that bind to the complement

256 use high-affinity recognition by overlapping peptide nucleic acids (PNAs) to identify nucleotides wit

257 The remarkable stability of peptide nucleic acids (PNAs) towards enzymatic degradati

258 In this communication, we show that peptide nucleic acids (PNAs) with lengths of 15-20 nucle

259 Peptide nucleic acids (PNAs), analogs of DNA or RNA whic

260 triplex-forming oligonucleotides (TFOs) and peptide nucleic acids (PNAs), can be utilized to introdu

261 rapeutic (FAST) platform to create antisense peptide nucleic acids (PNAs), gene-specific molecules de

262 ergence of triplex-forming oligonucleotides, peptide nucleic acids (PNAs), minor groove binding polya

263 sical properties, we explore the assembly of peptide nucleic acids (PNAs), which are short DNA mimics

264 tion of G-quadruplexes could be induced with peptide nucleic acids (PNAs).

265 ments for efficient and nontoxic delivery of peptide nucleic acids (PNAs).

266 ligands and as a modified backbone unit for peptide nucleic acids (PNAs).

267 with temperature gradient focusing (TGF) and peptide nucleic acids (PNAs).

268 are subunits of the proposed RNA precursor, peptide nucleic acids (PNAs).

269 ies superior to those possessed by analogous peptide nucleic acids (PNAs).

270 gress with triplex-forming oligonucleotides, peptide nucleic acids, polyamides, and other approaches,

271 Peptide nucleic acids possess enormous potential because

272 erstand how the addition of mutations to the peptide nucleic acid probe could enhance the selectivity

273 In each case, fluorescence intensity of a peptide nucleic acid probe specific for telomeric sequen

274 ocked by electrophoretically mobilized bead-(peptide nucleic acid probe) conjugates upon hybridizatio

275 rt 21 base-long RNA target to an immobilized peptide nucleic acid probe, while fragmented mRNA target

276 retreatment T790M resistance mutation with a peptide nucleic acid probe-based real-time PCR.

277 ysis or flow-FISH with a fluorescein-labeled peptide nucleic acid probe.

278 es, fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) and matrix-assist

279 Peptide nucleic acid probes complimentary to the G12V mu

280 al nucleic acid sensors based on fluorogenic peptide nucleic acid probes embedded in permeable, physi

281 oligonucleotide-templated reactions between peptide nucleic acid probes embedded within permeable ag

282 lization, hybridization of cellular DNA with peptide nucleic acid probes with cells intact, and analy

283 d-tube PCR analysis using a quencher-labeled peptide nucleic acid (Q-PNA) probe.

284 at provide small molecular mimics to explore peptide-nucleic acid recognition have been prepared.

285 utic applications, intracellular delivery of peptide nucleic acids remains a challenge.

286 Furthermore, a pyrrolidinyl peptide nucleic acid (so-called "acpcPNA") was used as a

287 so delivered a biotinylated 18-mer antisense peptide-nucleic acid specific for the rev gene of HIV-1

288 ransfer (CT) properties are compared between peptide nucleic acid structures with an aminoethylglycin

289 f the net increase in negative charge at the peptide nucleic acid surface that occurs upon single-str

290 mplexity, foreshadowing today's encapsulated peptide-nucleic acid system.

291 pecific motif sites with fluorescent bisPNA (Peptide Nucleic Acid) tags.

292 First, using a peptide nucleic acid templated system, we identified the

293 Using L-lysine gamma-substituted peptide nucleic acids, the multivalent effects of an int

294 n of isotopomer tandem nucleic acid mass tag-peptide nucleic acid (TNT-PNA) conjugates is described a

295 can generally be used to effectively deliver peptide nucleic acids to adipose tissue.

296 he progress that has been made in delivering peptide nucleic acids to intracellular targets.

297 have designed FIT-PNAs (forced-intercalation-peptide nucleic acids) to detect two RNA cancer biomarke

298 simple oligo-dipeptide backbones [thioester peptide nucleic acids (tPNAs)] and undergoes dynamic seq

299 A-norbornyl monomers to yield poly-PNA (poly(peptide nucleic acid)) via ring-opening metathesis polym

300 -MOE)-phosphorothioate and PNA-4K oligomers (peptide nucleic acid with four lysines linked at the C t