ライフサイエンスコーパス: peptidergic

1 Transmission at this synapse is peptidergic.

2 extracellular peptidase activity sculpts the peptidergic actions of modulatory projection neurons on

3 Neurotransmission from sympathetic and peptidergic afferent fibers participates in the regulati

4 transmission inhibits exocytosis from pulpal peptidergic afferent fibers.

5 ts in craniofacial muscles are predominantly peptidergic afferents enriched with TRPV1.

6 ransmission by myelinated, unmyelinated, and peptidergic afferents in the dorsal horn.

7 calcitonin gene-related peptide (iCGRP) from peptidergic afferents innervating bovine dental pulp.

8 conditions, we investigated whether the non-peptidergic afferents project to tooth pulp as potential

9 jority of 5-HT1D-IR neurons are unmyelinated peptidergic afferents that distribute peripherally, incl

10 e significantly smaller than those formed by peptidergic afferents, but provide a substantial proport

11 For clear visualization of the non-peptidergic afferents, we took advantage of a recently g

12 sses of neurotensinergic and, perhaps, other peptidergic afferents.

13 genous KOR agonist U69593 and the endogenous peptidergic agonist dynorphin A (1-13) showed differenti

14 postsynaptic responses were compared between peptidergic and cholinergic synapses formed by cell B2.

15 cium concentrations ([Ca2+]i) for triggering peptidergic and cholinergic transmission were estimated

16 tophysin was predominantly expressed in both peptidergic and IB4-binding C fiber populations in super

17 rrelated with immunohistochemical changes of peptidergic and non-peptidergic epidermal nerve fibers i

18 When labeling both peptidergic and non-peptidergic nerve fibers with the pa

19 ferentiation, and target innervation of both peptidergic and nonpeptidergic DRG sensory neurons.

20 ated by most CGRP(+) neurons, revealing that peptidergic and nonpeptidergic epidermal innervation is

21 rs, evoked by the remote stimulation of both peptidergic and nonpeptidergic nociceptive fibers as ind

22 We found that NT5E was located on peptidergic and nonpeptidergic nociceptive neurons in do

23 ecular weight hyaluronan (LMWH) acts at both peptidergic and nonpeptidergic nociceptors to induce mec

24 pressing TrkA and enhancing Ret signaling in peptidergic and nonpeptidergic nociceptors, respectively

25 itical modifier of TrkA and Ret signaling in peptidergic and nonpeptidergic nociceptors.

26 y tracked changes in two subsets of neurons: peptidergic and nonpeptidergic nociceptors.

27 These findings suggest single peptidergic and nonpeptidergic sensory neurons in DRG ar

28 The peptidergic and nonpeptidergic small-diameter primary af

29 d the hypothesis that dysfunction of the CRH peptidergic and noradrenergic systems observed in patien

30 = 7.2) in mammalian cells is not present in peptidergic and small synaptic vesicles of the Drosophil

31 that the neurons generated are cholinergic, peptidergic, and ciliated putative proprioceptors which

32 monosynaptic input includes adrenergic (C1), peptidergic, and noncatecholaminergic neurons.

33 therapy would have higher potential than the peptidergic approach for future translation due to its i

34 s express TRPV1 and the majority of them are peptidergic, as revealed by simultaneous immunostaining

35 equires Galphaq and Galphas signaling in the peptidergic ASI sensory neurons, with an array of ASI ne

36 lcitonin gene-related peptide immunolabeled (peptidergic) axons ended mostly in simple terminals, whe

37 leased peptides from the well-characterized, peptidergic bag cell neurons of Aplysia californica were

38 lack N-cadherin, whereas the majority of the peptidergic C-fiber synapses in the outer half of lamina

39 t secretion of neuropeptides and channels in peptidergic C-type nociceptors facilitates a rapid modul

40 MCN1 activates this rhythm by slow peptidergic (CabTRP Ia) and fast GABAergic excitation of

41 itis elegans through a complex monoaminergic/peptidergic cascade, and suggest that this model may be

42 CANCE STATEMENT C1 neurons are glutamatergic/peptidergic/catecholaminergic neurons located in the med

43 othesis that DIMM is a master regulator of a peptidergic cell fate in Drosophila and provides a detai

44 ied multiple monoaminergic, cholinergic, and peptidergic cell types linked to alertness and found tha

45 To investigate dynamic peptidergic cell-cell communication, single micrometer-s

46 When Spn4.1 is overexpressed in specific peptidergic cells of Drosophila larvae, the animals exhi

47 ntiation of secretory properties in numerous peptidergic cells of Drosophila melanogaster.

48 ipRGCs form synaptic contacts with major peptidergic cells of the SCN, including VIP, GRP, and ar

49 lect a specific neuropeptide identity within peptidergic cells.

50 ptidergic Mrgprd(+) neurons and axons, while peptidergic CGRP(+) neurons were not significantly label

51 constitute two separate subpopulations: the peptidergic CGRP/somatostatin+ cells expressing GDNF and

52 Therefore, GDNF released from peptidergic CGRP/somatostatin+ nociceptors acutely depre

53 Functionally, endogenous GDNF released from peptidergic CGRP/somatostatin+ nociceptors upon capsaici

54 ed (NF200-) sensory neurons that were either peptidergic (CGRP+) or nonpeptidergic (CGRP-).

55 These findings define a linear peptidergic circuit that links the clock to motor output

56 We also reconstruct a peptidergic circuitry comprising the sensory nuchal orga

57 eptide ligands and a common feature of other peptidergic class A GPCRs.

58 Our work identifies a peptidergic connection between the large LNvs and a grou

59 pression mapping to analyze the synaptic and peptidergic connectome of an entire neurosecretory cente

60 ive basal epithelial leash orientations, and peptidergic content of canine corneal innervation.

61 control of onset and maintenance as well as peptidergic control of arousal, support the idea that fe

62 Lastly, peptidergic corelease enhances ACh-evoked responses in M

63 rodotoxin insensitive and was blocked by the peptidergic CRF-R1 antagonist astressin.

64 nociceptors, the receptor is concentrated on peptidergic dense core vesicles (DCVs) and is notably ab

65 The peptidergic dorsal paired medial (DPM) neurons, which in

66 specifically expressed in a small subset of peptidergic dorsal root ganglion neurons, whereas expres

67 ave characterized the expression of TRPC4 in peptidergic DRG neurons and showed that acute itch induc

68 ory glutamatergic and excitatory cholinergic/peptidergic drives in the absence of food.

69 any US Food and Drug Administration-approved peptidergic drugs activate human MCs through a novel GPC

70 Food and Drug Administration (FDA)-approved peptidergic drugs associated with allergic-type injectio

71 behavior by stepwise recruitment of central peptidergic ensembles.

72 matory pain and for postnatal maintenance of peptidergic epidermal innervation.

73 histochemical changes of peptidergic and non-peptidergic epidermal nerve fibers in a rat model of ner

74 ription factor that can direct an inhibitory peptidergic fate.

75 nt, there was an increase in sympathetic and peptidergic fiber density in the ankle joint synovium.

76 We also observed a sympathetic, but not peptidergic, fiber sprouting in the skin over the joint,

77 e vagina indicated the likely origin of some peptidergic fibers.

78 and determines neuron-specific variation in peptidergic function.

79 Salvinorin A is unique among ligands for peptidergic G protein-coupled receptors in being nonnitr

80 the human OX2R expands our understanding of peptidergic GPCR ligand recognition and will aid further

81 hilic hotspots and water molecules for these peptidergic GPCR targets.

82 However, the relationship between the peptidergic identity of neurons and their roles in behav

83 sly promote characteristics of an inhibitory peptidergic identity, providing the first example of a s

84 Peptidergic influences on Renshaw cells were assessed in

85 behavioral and cell physiological effects of peptidergic inhibition on serotonin neurons.

86 The presence of marked alterations in peptidergic innervation and positive response to topical

87 n the DR receive excitatory, inhibitory, and peptidergic inputs from the same specific brain regions.

88 ed the density of AgRP-containing fibers and peptidergic inputs onto identified preautonomic, but not

89 n directs cell type-specific patterns of ARH peptidergic inputs onto preautonomic neurons in the PVH,

90 s highlight the complexity of octopaminergic/peptidergic interactions, the role of OA in activating g

91 stimulatory alpha(1)-receptors on inhibitory peptidergic interneurons.

92 upport the hypothesis that the histaminergic/peptidergic IV neurons are projection neurons with direc

93 crol) of either peptidergic (Sendide) or non-peptidergic (L703, 606) neurokinin 1 (NK1) receptor anta

94 he avian medial septum is clearly defined by peptidergic markers and choline acetyltransferase immuno

95 e affected via a muscarinic cholinergic or a peptidergic mechanism, with a much smaller superimposed

96 Peptidergic mechanisms controlling feeding, metabolism,

97 cal plan for understanding how aminergic and peptidergic modulation of behaviour is achieved by speci

98 riming of B48 may be implemented by a direct peptidergic modulation of its intrinsic characteristics

99 To better understand the noradrenergic/peptidergic modulation of nociception, we examined the o

100 ults provide neuroanatomical support for the peptidergic modulation of Renshaw cells.

101 est that astrocytes could play a role in the peptidergic modulation of synaptic signaling in the CNS.

102 When labeling both peptidergic and non-peptidergic nerve fibers with the pan-neuronal marker PG

103 ssion of the P2X3 receptor, a marker for non-peptidergic nerve fibers, was not only significantly red

104 alcitonin gene-related peptide, a marker for peptidergic nerve fibers, was not significantly changed

105 Peptidergic nerve terminals of the neurohypophysis (NH)

106 lls resembled the effects on fusion pores in peptidergic nerve terminals.

107 ting a functional connection between the two peptidergic nervous systems.

108 n requires mapping cell types, synapses, and peptidergic networks.

109 rth and reveal key molecular components of a peptidergic neural circuit that supports breathing at a

110 ons use synaptic transmission in addition to peptidergic neuromodulation and identify acetylcholine a

111 at repetition priming may involve persistent peptidergic neuromodulation.

112 tress responses and is influenced by several peptidergic neuromodulators.

113 specific, testable predictions regarding 37 peptidergic neuromodulatory networks that may play promi

114 Consistent with peptidergic neuron function, unc-73 RhoGEF-2 mutants exh

115 ger transcription factor PAG-3/Gfi to induce peptidergic neuron identity and directs UNC-86 to induce

116 rker vanilloid receptor subtype 1, the small peptidergic neuron markers substance P and calcitonin ge

117 des and circuits that promote feeding, but a peptidergic neuron subset whose activation inhibits feed

118 tion of this vital insect behavior are under peptidergic neuronal control.

119 tion-induced wakefulness to a single pair of peptidergic neurons and their partners.

120 These data suggest that nonpeptidergic and peptidergic neurons are susceptible to pathologic change

121 Nonpeptidergic and peptidergic neurons colocalized with nuclear-accumulated

122 Here we describe a novel set of peptidergic neurons conserved throughout all development

123 npeptidergic neurons 1 d postinjury, whereas peptidergic neurons did not display any significant chan

124 phila larvae, and then decoded by a group of peptidergic neurons for executing binary escape decision

125 tron microscopy (ssTEM) to identify multiple peptidergic neurons in a connectome.

126 d secretion of egg-laying hormone (ELH) from peptidergic neurons in intact nervous tissue of Aplysia.

127 aboration in pigment dispersing factor (PDF) peptidergic neurons in the adult brain.

128 Small- to medium-diameter non-peptidergic neurons in the neonatal DRG express function

129 argeted both parvicellular and magnocellular peptidergic neurons in the paraventricular and supraopti

130 adian rhythms in two of the major classes of peptidergic neurons in the SCN: AVP (arginine vasopressi

131 n-1 (IL-1) challenge based on its content of peptidergic neurons involved in feeding, its expression

132 We found that UNC-73E acts within peptidergic neurons of mature animals to regulate locomo

133 TGR5 was detected in peptidergic neurons of mouse dorsal root ganglia and spi

134 These effects suggest that the peptidergic neurons of the EW regulate food consumption.

135 ell populations showed that multiple sets of peptidergic neurons play similar behavioral roles in thi

136 ent of dFMRP for the retention of transitory peptidergic neurons shows evident circuit specificity.

137 DCV distribution analysis in peptidergic neurons suggest the two kinesins have compar

138 One class was peptidergic neurons that had nerve endings in circular m

139 coded by the amnesiac gene and released from peptidergic neurons that innervate mushroom body neurons

140 g hormone), and we show that the response of peptidergic neurons that produce CCAP (crustacean cardio

141 have identified two genes and a small set of peptidergic neurons that regulate sensitivity to ethanol

142 YO recruits brainstem noradrenergic (NA) and peptidergic neurons that relay viscerosensory signals to

143 in the number of PAR2- and TRPV1-expressing peptidergic neurons together with a shift of TRPV1 recep

144 ase C (PKC) potentiates secretion in Aplysia peptidergic neurons, in part by inducing new sites for p

145 emonstrate that cholinergic neurons, but not peptidergic neurons, of the medial habenula (MHb) displa

146 -modulating dopaminergic and Fru(M)-positive peptidergic neurons, the downstream anatomical targets o

147 eptor TYRA-3 on inhibitory monoaminergic and peptidergic neurons.

148 m leads to constitutive maintenance of these peptidergic neurons.

149 specification of dorsal horn pain-modulatory peptidergic neurons.

150 on, triggers ectopic FMRFamide expression in peptidergic neurons.

151 meliorate damage to the DRG, specifically to peptidergic neurons.

152 reserve epidermal innervation in a subset of peptidergic neurons.

153 ansmitters, yet there is little evidence for peptidergic neurotransmission in the mammalian CNS.

154 dendrites but not at nerve terminals, where peptidergic neurotransmission occurs.

155 so show that Ptf1a induces expression of the peptidergic neurotransmitter nociceptin, while minimally

156 To identify novel peptidergic neurotransmitters, the Caenorhabditis elegan

157 to spinal cord neurons via glutamatergic and peptidergic neurotransmitters.

158 cording of individual exocytotic events from peptidergic NHT.

159 When stimulated, SCCs trigger peptidergic nociceptive (or pain) nerve fibers, causing

160 rresponding to murine MrgprD-expressing, non-peptidergic nociceptive afferents.

161 revealed that regenerating fronds contained peptidergic nociceptive fibers (positive for calcitonin

162 nctional B1 receptor expression in small non-peptidergic nociceptive neurones.

163 arker; TH), calcitonin gene-related protein (peptidergic nociceptor marker; CGRP), and/or neurofilame

164 is of mouse nonpeptidergic nociceptors (NP), peptidergic nociceptors (PEP), and large myelinated sens

165 ocessing nociception, we sparsely traced non-peptidergic nociceptors across the body using a newly ge

166 lectively expressed by a subset of mouse non-peptidergic nociceptors and functions as the molecular r

167 results provide convincing evidence that non-peptidergic nociceptors are projected into the tooth pul

168 lly reduced proalgesic TRPV1 potentiation in peptidergic nociceptors by abrogating its Ca(2+)-depende

169 Specifically, TrkA+ peptidergic nociceptors require TNF-alpha-TNFR1 forward

170 as expressed mainly in the IB4-positive, non-peptidergic nociceptors that also express the sodium-act

171 membrane is a mechanism specifically used by peptidergic nociceptors to potentiate their excitability

172 However, the projection of non-peptidergic nociceptors to tooth pulp is controversial.

173 ctin B4 (IB4), a neurochemical marker of non-peptidergic nociceptors, but is rarely co-localized with

174 ltiple sensory neuron subsets, predominantly peptidergic nociceptors, innervate LNs, distinct from th

175 TRPC3, is highly expressed in MRGPRD(+) non-peptidergic nociceptors, raising the possibility of whet

176 rin or SSP-saporin (which deplete IB4(+) and peptidergic nociceptors, respectively), or their combina

177 ory neurons as well as a small population of peptidergic nociceptors, whereas DPP6 is absent in senso

178 diated by isolectin B4-positive (IB4(+)) and peptidergic nociceptors, whereas priming is dependent on

179 oduced by LDM is mediated by both IB4(+) and peptidergic nociceptors, whereas priming is not dependen

180 ysteine protease activity directly activated peptidergic nociceptors, which are neuropeptide-producin

181 ed role of alphaCGRP in LDCV mobilization in peptidergic nociceptors.

182 nduced by HDM is mediated by both IB4(+) and peptidergic nociceptors.

183 HDM is, however, mediated by both IB4(+) and peptidergic nociceptors.

184 nd/or pharmacological ablation of the TRPV1+/peptidergic or the MrgprD+/non-peptidergic subset of noc

185 The MOR is expressed in peptidergic pain fibers, the DOR in myelinated and nonpe

186 These results reveal an essential role of a peptidergic pathway in camouflage that is regulated by l

187 behavioral abnormalities related to specific peptidergic pathways.

188 opment of therapeutic approaches targeted to peptidergic pathways.

189 to signal changes in oxygen availability to peptidergic pathways.

190 s identify the estrogen receptor content and peptidergic phenotype of afferents.

191 ne production indirectly by contributing the peptidergic phenotype of the PTTH-producing neurons in t

192 s a retrograde signal that helps specify the peptidergic phenotype of the Tv neurons.

193 HA) of chronically dehydrated rats for their peptidergic phenotype, colocalization, and activation pr

194 One subtype is non-peptidergic, placodal in origin, expresses P2X2 and P2X3

195 though ENT1 was most highly expressed in the peptidergic population.

196 ly, we addressed the question of whether the peptidergic post-oesophageal commissure (POC) neurons tr

197 rokinin 1 receptor are densely innervated by peptidergic primary afferent nociceptors and more sparse

198 Cepsilon could be found in the population of peptidergic primary afferent nociceptors where deltaORs

199 To study the involvement of peptidergic primary afferents in the activation of DNIC

200 read in the spinal nociceptive system and in peptidergic primary afferents it appears to be specifica

201 in gene-related peptide (CGRP), a marker for peptidergic primary afferents, in the L5 DRG.

202 related peptide (CGRP), which labels somatic peptidergic primary afferents.

203 several steroid hormones, targeted TRPA1 in peptidergic primary sensory neurons in rodent and human

204 tide (CGRP) is a classic molecular marker of peptidergic primary somatosensory neurons.

205 These data predict that this GABA/peptidergic projection modulates septohippocampal activi

206 rom recent work on the actions of identified peptidergic projection neurons acting on the multifuncti

207 brain regions by parallel noradrenergic and peptidergic projection pathways arising within the NST.

208 halamus (LH) sends a dense glutamatergic and peptidergic projection to dopamine neurons in the ventra

209 pression of an inhibitory NPVF-ventral raphe peptidergic projection.

210 making distinct contacts when compared with peptidergic projections.

211 elective peptide and non-peptide ligands for peptidergic receptors are anticipated to help further un

212 Here we report peptidergic regulation of preoptic glutamatergic neurons

213 e to a prolonged rise in [Ca2+]i, while some peptidergic release appears to persist for as long as [C

214 Here, we describe a peptidergic scorpion toxin (WaTx) that activates TRPA1 b

215 ing (AS) of pre-mRNAs encoding regulators of peptidergic secretion within pancreatic beta cells that

216 RMG signals high O2 by peptidergic secretion.

217 totagmin-10 localizes to a distinct class of peptidergic secretory vesicles containing IGF-1.

218 fferent doses (100 nmol; 1 microl) of either peptidergic (Sendide) or non-peptidergic (L703, 606) neu

219 literature suggesting that glutamatergic and peptidergic sensory afferents may be distinct population

220 elective cation channel that is expressed in peptidergic sensory neurons and fibroblasts.

221 (GFRalpha3) is expressed by sympathetic and peptidergic sensory neurons that are also the primary si

222 ropic affinity to large myelinated and small peptidergic sensory neurons that innervate bone, compare

223 s that innervate bone, compared to small non-peptidergic sensory neurons that rarely innervate bone.

224 ts become restricted to a specific subset of peptidergic sensory neurons.

225 Peptidergic signaling can involve juxtacrine, paracrine,

226 unctions as part of a complex, monoaminergic/peptidergic signaling cascade and appears to selectively

227 cilia suggest that ciliary ectosome-mediated peptidergic signaling dates to the early eukaryotes and

228 The evolution of peptidergic signaling has been accompanied by a signific

229 as hindered our understanding of its role in peptidergic signaling in insects.

230 and is translated by both monoaminergic and peptidergic signaling in the fine-tuning of most behavio

231 In contrast, peptidergic signaling is required to generate preference

232 ing monooxygenase (PAM), and the presence of peptidergic signaling machinery (including propeptide pr

233 We found that peptidergic signaling mediated by FMRF-amide like neurop

234 with this, genetic studies place HID-1 in a peptidergic signaling pathway.

235 deficits in salt attraction, suggesting that peptidergic signaling potentiates responses to high salt

236 The peptidergic signaling system is an ancient cell-cell com

237 cteristics that uncover additional potential peptidergic signaling systems.

238 Neurosecretory centers in animal brains use peptidergic signaling to influence physiology and behavi

239 Our study uncovered extensive networks of peptidergic signaling within a neurosecretory center and

240 -based analyses provide a new perspective on peptidergic signaling within the SCN and demonstrate tha

241 ion in mammals that also involves inhibitory peptidergic signaling.

242 actions, the role of OA in activating global peptidergic signalling cascades and the similarities of

243 ing attraction or repulsion, suggesting that peptidergic signalling may integrate multiple sensory in

244 As in other vertebrates, the peptidergic somata lie in the anterolateral hypothalamus

245 f stimulus-transcription coupling after this peptidergic stimulus to chromaffin cells.

246 in vitro, with differences identified in non-peptidergic [strongly isolectin B4 (IB4)-positive] and p

247 Hb are divided into discrete cholinergic and peptidergic subnuclei that differ in size between the le

248 Recently, the non- peptidergic subset of nociceptors has been implicated in

249 of the TRPV1+/peptidergic or the MrgprD+/non-peptidergic subset of nociceptors produced selective, mo

250 The nasal epithelium is richly invested with peptidergic (substance P and calcitonin gene-related pep

251 are endogenously modulated by aminergic and peptidergic substances.

252 Several peptidergic subtypes of parvocellular neuron, identified

253 In carriers, both skin denervation and peptidergic sudomotor denervation were evident: (1) IENF

254 co-cultured with sensory neurons (SNs), slow peptidergic synapses are formed.

255 vide the first example of a function for any peptidergic system in hearing.

256 and amphetamine-regulated transcript (CART) peptidergic system is involved in processing diverse neu

257 The peptidergic system is the most abundant network of ligan

258 oanatomical and physiological input from CRF peptidergic system onto hypocretin neurons.

259 An arthropod-specific peptidergic system, the neuropeptide designated here as

260 er understanding of the evolution of the MCH peptidergic system.

261 hips between protostomian and deuterostomian peptidergic systems (PSs).

262 us, dysfunctional interactions between these peptidergic systems could be involved in the development

263 vagal gustatory lobe of goldfish, while both peptidergic systems distribute to the primary visceral s

264 in (Hcrt) and nociceptin/orphanin FQ (N/OFQ) peptidergic systems in the regulation of SIA.

265 The strong involvement of these peptidergic systems with the hypothalamus and general vi

266 ave demonstrated phylogenetic variability of peptidergic systems, this study suggests that serotonerg

267 The ligands for peptidergic targets, such as peptide GPCRs and integrin

268 e bullwhip and mini-bullwhip cells and their peptidergic terminals that are concentrated in the CMZ n

269 y Calcitonin-Gene-Related-Peptide (CGRP) for peptidergic terminals, and by Isolectin-B4 (IB4) for non

270 The combinatorial peptidergic therapy of islet amyloid polypeptide (IAPP)

271 experiments demonstrate that this surprising peptidergic transmission requires cAMP-dependent protein

272 , adrenergic, serotonergic, cholinergic, and peptidergic transmission.

273 rovides a mechanism for activity-independent peptidergic transmission.

274 to exert considerable dynamic influence over peptidergic transmitter synthesis by altering the activi

275 teristics of the actions of conventional and peptidergic transmitters.

276 Chemical ablation of peptidergic trigeminal fibers prevented the SCC-induced

277 SCCs are innervated by peptidergic trigeminal nerve fibers but it is currently

278 use cholinergic neurotransmission to trigger peptidergic trigeminal nociceptors, which link SCCs to t

279 Peptidergic trigeminal sensory fibers also enter the glo

280 be further subdivided into two phenotypes, a peptidergic TRKA(+) and GFRalpha3(+) subpopulation, and

281 +) and GFRalpha3(+) subpopulation, and a non-peptidergic TRKB(+) and GFRalpha1(+) subpopulation.

282 t B; CTB) than with a tracer that labels non-peptidergic unmyelinated afferents (Griffonia simplicifo

283 als in laminae I and IIo and in terminals of peptidergic unmyelinated afferents, it is suggested that

284 but very few expressed the IB4 marker of non-peptidergic unmyelinated afferents.

285 A-988315, a selective and highly potent non-peptidergic V1b-receptor antagonist with good pharmacoki

286 protein gene product 9.5 (SGII[PGP9.5]) and peptidergic vasoactive intestinal peptide (SGII[VIP]), a

287 anogaster neuromuscular junctions shows that peptidergic vesicle behavior in nerve terminals is sensi

288 it through resting terminals, but retrograde peptidergic vesicle flux is accessed following activity

289 Peptidergic vesicle mobilization and post-tetanic potent

290 ntial activity and which regulates behavior, peptidergic vesicle movement has not been examined in li

291 om Topaz-tagged atrial natriuretic factor, a peptidergic vesicle pH indicator, is only modestly affec

292 Specifically, peptidergic vesicles are immobile in resting synaptic bo

293 Quantitation shows that peptidergic vesicles are nearly neutral (pH = 6.74 +/- 0

294 peptide stores are limited by the capture of peptidergic vesicles at the terminal, rather than by syn

295 Peptidergic vesicles continually transit through resting

296 leled by a twofold increase in the number of peptidergic vesicles docked at the portion of the termin

297 is differential targeting of cholinergic and peptidergic vesicles may play a significant role in the

298 ing a radioimmunoassay, and the targeting of peptidergic vesicles was quantified using immunoelectron

299 ied with synaptophluorin, are as alkaline as peptidergic vesicles.

300 c [strongly isolectin B4 (IB4)-positive] and peptidergic [weakly IB4-positive (IB4+) and IB4-negative