ライフサイエンスコーパス: perianal

1 imaging findings secondary to a supralevator perianal abscess causing irritation of the sciatic nerve

2 ment of ADC values is reliable in diagnosing perianal abscess collection.

3 The perianal abscess was extending above the levator ani mus

4 ne; however, on STIR coronal images, a right perianal abscess with air pockets was seen.

5 d, peritoneal fluid, bone, synovial fluid, a perianal abscess, and an arm wound.

6 nt resolution of the infra- and supralevator perianal abscess.

7 h aberrant skin window results and recurrent perianal abscesses and pretibial lesions diagnosed as py

8 Perianal abscesses must be drained.

9 endicitis, cholecystitis, diverticulitis and perianal abscesses) admissions.

10 ad abdominal infections after surgery, 4 had perianal abscesses, 13 had wound infections, and 1 had C

11 ronal sulcus, penile shaft/prepuce, scrotal, perianal, anal canal, semen, and urine samples were obta

12 mated IP incidence (penile/scrotal, perineal/perianal, anal) for 4vHPV and 9-valent (9v) HPV vaccine

13 The perianal and abdominal wall lesions were suspected to be

14 h strong agreement observed between perineal/perianal and anal sites among MSM for HPV6 (Cohen's kapp

15 (eg, mesenteric adenopathy in two patients, perianal and enterocolic fistulas in one patient) not de

16 Four of the 5 patients with complex perianal and fistulizing disease had closure of all fist

17 In addition, skin samples were paired with perianal and rectal locations to evaluate changes in the

18 6.8 (4.9-9.2) and 9.0 (6.9-11.6) at perineal/perianal, and 12.0 (9.4-15.1) and 16.8 (13.7-20.2) at an

19 Sputum, perianal, and arm/leg cultures were tested for A baumann

20 line prevalence of penile, scrotal, perineal/perianal, and intra-anal human papillomavirus (HPV) infe

21 In our cohort, monkeypox caused genital, perianal, and oral lesions and complications including p

22 nitals (n=111 participants, 56.3%) or in the perianal area (n=82, 41.6%).

23 The perianal area is worthy of attention during melanoma scr

24 Cultures of skin, respiratory tract, and the perianal area were obtained from participants and evalua

25 were obtained from patients' anterior nares, perianal area, and skin of the chest and arm to assess b

26 specimens from the nares, oropharynx, groin, perianal area, and wounds were prospectively cultured mo

27 cant for the scrotum, semen, anal canal, and perianal area.

28 phologic features of melanocytic nevi in the perianal area.

29 tal swabs of the vulvar, cervicovaginal, and perianal areas for HSV culture, maintained a diary of ge

30 Surveillance cultures (sputum, perianal, arm/leg, and axilla/groin) were obtained from

31 s develop in axillary, inguinal, gluteal and perianal body sites.

32 Thereafter, perianal bulking agents, sacral neuromodulation and othe

33 6 consecutive patients with CD, 24% (86) had perianal CD (age range, 14-83 years), and women were sli

34 The management of perianal CD continues to be challenging.

35 Perianal CD patient derived rectal organoids reflect gen

36 CD associated with perianal CD was limited to the small bowel and/or ileoco

37 severe luminal and/or fistulizing (including perianal) CD often requires the use of immunomodulator (

38 Information about vulvovaginal and perianal condylomata acuminata and intraepithelial neopl

39 Vulvovaginal and perianal condylomata acuminata or intraepithelial neopla

40 nd anal canal stenosis are manifestations of perianal Crohn disease (CD).

41 y being familiar with MR imaging features of perianal Crohn disease and knowledgeable about what feat

42 Emerging innovative treatments for perianal Crohn disease are now available and have the pr

43 mmatory bowel disease consistent with severe perianal Crohn disease).

44 maging is currently the standard for imaging perianal Crohn disease.

45 ignificantly improved both their mean Wexner Perianal Crohn's Disease Activity Index and McMaster Per

46 Crohn's Disease Activity Index and McMaster Perianal Crohn's Disease Activity Index quality-of-life

47 s disease, Crohn's disease in remission, and perianal Crohn's disease that emphasizes recent advances

48 ting a more aggressive operative approach to perianal Crohn's disease.

49 but not fistula remission, in patients with perianal Crohn's disease.

50 determining fistula anatomy in patients with perianal Crohn's disease.

51 active IBD, ileal pouch-anal anastomosis, or perianal Crohn's disease.

52 one, with the exception of women with active perianal Crohn's disease.

53 l Center from 2001 through 2006 had multiple perianal culture samples collected.

54 ratory illness, n = 1; foot blisters, n = 1; perianal dermatitis, n = 1).

55 rst 3 months of life and was associated with perianal disease (16 of 16 patients).

56 estry proportion was lower in the group with perianal disease (33.5% versus 39.5%, P value = 0.03).

57 in those with penetrating behaviour (B3) and perianal disease (4/31, p < 0.05).

58 patients with stricturing behaviour (B2) and perianal disease (7/11, p < 0.02) and less prevalent in

59 , 3.3; 95% CI, 1.1-9.4; p = 0.030), previous perianal disease (OR, 22; 95% CI, 7-69; p < 0.001), acti

60 se (OR, 22; 95% CI, 7-69; p < 0.001), active perianal disease (OR, 96; 95% CI, 21-446; p < 0.001) and

61 have a current smoking habit (P < .001) with perianal disease (P = .046) and undergoing treatment wit

62 ection section was not protective of ongoing perianal disease activity post-delivery, but should be r

63 and define genotype-phenotype associations (perianal disease and defective antimicrobial activity).

64 Smoking and perianal disease at baseline were independent factors as

65 Perianal disease occurs in up to 34% of inflammatory bow

66 gs indicate that infantile IBD patients with perianal disease should be screened for IL-10 and IL-10R

67 es in behavior, whereas the association with perianal disease was barely significant.

68 Clinical data of patients affected by perianal disease were routinely and prospectively insert

69 ubgroup of mice (approximately 5%) developed perianal disease with ulceration and fistulae.

70 to corticosteroids, or development of severe perianal disease) (n = 67).

71 Activity Index [CDAI] > 200 and/or draining perianal disease) initiated therapy with thalidomide, 20

72 r smoking and 3.97 [2.17-7.25; p<0.0001] for perianal disease) on multivariate analysis.

73 ellin, and OmpC), NOD2/CARD15 polymorphisms, perianal disease, and ethnicity were risk factors for pe

74 often presents with intestinal stricturing, perianal disease, and failed response to conventional tr

75 ient patients had intractable enterocolitis, perianal disease, and fistula formation.

76 the anastomosis technique, the management of perianal disease, and the role of laparoscopic surgery a

77 cterized by granulomatous colitis and severe perianal disease, we identified a homozygous variant of

78 might cause granulomatous colitis and severe perianal disease, with recurrent bacterial and viral inf

79 nic location, and stricturing behaviour with perianal disease.

80 s were the presence of ileal involvement and perianal disease.

81 dilemma of whether mode of delivery affects perianal disease.

82 stations in the setting of previously healed perianal disease.

83 eas men were more likely to have perineal or perianal disease.

84 s with an HM is more likely to cause diffuse perianal edema and is less likely to cause fistulas than

85 atients with an HM had significantly greater perianal edema than did control patients (mean arc angle

86 scesses and/or fistula tracts, the extent of perianal edema, and the likely diagnosis.

87 Perianal EMPD also had the highest rate of invasive dise

88 Perianal EMPD cases recurred in one-third of cases (74/2

89 in vulvar EMPD and metastatic recurrence in perianal EMPD.

90 Swabs of labial, vulvar, perineal, perianal, endocervical, and ectocervical tissue were obt

91 ements between CT and MRI image in measuring perianal fat thickness(r = 0.823, P < 0.001), AreaM (r =

92 ur results demonstrated that measurements of perianal fat thickness, AreaM and AreaH based on MRI ima

93 W imaging is a reliable sequence to diagnose perianal fistula and its complications.

94 I sequence and other sequences in diagnosing perianal fistula and its complications.

95 nce in the detection and characterization of perianal fistula as compared to the routinely used T2 FS

96 equence in depiction and characterization of perianal fistula by using the contrast-enhanced (CE) 3D

97 an improve detection and characterization of perianal fistula compared with two-dimensional (2D) sequ

98 For diagnosis and prevention of recurrence, perianal fistula imaging (PFI) is crucial.

99 A perianal fistula is an abnormal tract connection between

100 Perianal fistula is an important health problem with dev

101 Diagnosis of perianal fistula represents a challenge for surgeons.

102 n minimisation for participating centres and perianal fistula to receive laparoscopic ileocaecal rese

103 Fistula-in-ano, or perianal fistula, is a challenging clinical condition fo

104 rately for detection and characterization of perianal fistula, then comparison between of T2 and 3D V

105 of 47 patients with a clinical diagnosis of perianal fistula, who had an MRI study performed on a 1.

106 of medical therapy for Crohn's disease (CD) perianal fistula.

107 ery sensitive modality for the evaluation of perianal fistula.

108 leocolitis (but not isolated ileal disease), perianal fistulae and pouchitis, whereas selected probio

109 mental benefit of infliximab for treating CD perianal fistulae over a 1-year period may not justify t

110 The perianal fistulae were classified according to St James

111 Current therapies for complex Crohn's perianal fistulas (CPF) have a limited ability to achiev

112 o diagnose and describe the intersphincteric perianal fistulas (number, site, number of internal and

113 Perianal fistulas (PAFs) represent a severe complication

114 with anatomical and pathological findings of perianal fistulas and classify them using the MRI - base

115 In addition, the MR appearance of healing perianal fistulas and fistula complications is described

116 Perianal fistulas are a leading cause of patient morbidi

117 Perianal fistulas are common in patients with Crohn's di

118 city of different MR sequences in diagnosing perianal fistulas are T2 FSFSE: 92% sensitivity; DWI: 96

119 absence of collections >2 cm of the treated perianal fistulas confirmed by masked central MRI).

120 cally diagnosed of low-type intersphincteric perianal fistulas during April 2017-December 2022.

121 A total of 581 perianal fistulas from 549 patients were included in thi

122 Surgical approaches to perianal fistulas in CD are frequently ineffective and h

123 Complex perianal fistulas in Crohn's disease are challenging to

124 hly collected autologous adipose tissue into perianal fistulas in patients with CD.

125 onance imaging (MRI) index for assessment of perianal fistulas in patients with Crohn's disease (CD).

126 BACKGROUND & AIMS: Therapies for perianal fistulas in patients with Crohn's disease are o

127 Stem cell therapy for perianal fistulas in patients with Crohn's disease is a

128 an effective and safe treatment for complex perianal fistulas in patients with Crohn's disease who d

129 cy of Cx601 for treatment-refractory complex perianal fistulas in patients with Crohn's disease.

130 The perianal fistulas in the left posterior quadrant had a s

131 Perianal fistulas occur in up to 43% of patients with Cr

132 s adipose tissues were injected into complex perianal fistulas of 21 patients with CD, from March 201

133 adult patients who had draining abdominal or perianal fistulas of at least three months' duration as

134 isease and one or more draining abdominal or perianal fistulas of at least three months' duration.

135 In patients with Crohn's disease, perianal fistulas recur frequently, causing substantial

136 ix fistula plugs in 12 patients with chronic perianal fistulas to be safe and lead to clinical healin

137 Seventy-nine perianal fistulas were diagnosed in 47 patients who had

138 four patients with suspected Crohn's disease perianal fistulas were prospectively enrolled in a blind

139 e and treatment-refractory, draining complex perianal fistulas were randomly assigned (1:1) using a p

140 was to provide an overview for evaluation of perianal fistulas, examples of various fistula types and

141 n's disease and treatment-refractory complex perianal fistulas, we found Cx601 to be safe and effecti

142 In a study of 21 patients with CD and perianal fistulas, we found injection of recently collec

143 diagnosis and surgical planning of low-type perianal fistulas, with the offer of that it is a non-in

144 afe and effective method of treating complex perianal fistulas.

145 ging (MRI) for evaluation of Crohn's disease perianal fistulas.

146 and treatment-refractory, draining, complex perianal fistulas.

147 ium T1 FS has 100% sensitivity in diagnosing perianal fistulas.

148 decrease complications and recurrence of the perianal fistulas.

149 ) is an underutilized technique for defining perianal fistulas.

150 (Cx601) in patients with Crohn's disease and perianal fistulas.

151 clinical practice to gather better images of perianal fistulas.

152 x 10(7) MSCs appeared to promote healing of perianal fistulas.

153 It assesses MRI data and determines perianal fistulizing CD activity with improved operating

154 m endoscopic biopsies of each patient having perianal fistulizing CD or no disease controls were prep

155 trial of stem cell therapy for patients with perianal fistulizing CD.

156 comparing treatment effects in patients with perianal fistulizing CD.

157 Perianal fistulizing Crohn's disease (CD) is a severe ga

158 Patients with perianal fistulizing Crohn's disease have a poor prognos

159 Twenty-one patients with refractory perianal fistulizing Crohn's disease were randomly assig

160 with severe adverse events in patients with perianal fistulizing Crohn's disease.

161 at least 0.4 and the dependent variable was perianal fistulizing disease activity, measured on a 100

162 Of particular interest is the emergence of perianal fistulizing disease, to our knowledge the first

163 l of 50 consecutive patients presenting with perianal fistulous disease fulfilling the inclusion and

164 To diagnose and characterize the perianal fistulous disease using Magnetic resonance imag

165 Prior perianal involvement, perianal flare after delivery and delivery method were n

166 en (10%) experienced 21/322 (6%) post-partum perianal flares.

167 thesis of the natural compound isolated from perianal glandular pheromone secretion of the African ci

168 gia mainly on the left side, and genital and perianal hypoesthesia, which started suddenly 12 days be

169 s highly suggestive of group A streptococcal perianal infection (probability 83.3%).

170 Perianal infection in patients with an HM is more likely

171 we prospectively enrolled 132 children with perianal infections.

172 l, a proximal disease location, younger age, perianal involvement, and smoking were associated with l

173 Prior perianal involvement, perianal flare after delivery and

174 should be recommended for women with active perianal involvement.

175 on (C-section) or vaginal delivery influence perianal involvement.

176 of haemorrhoidal symptoms (rectal bleeding, perianal irritation and prolapse), the best option for t

177 All children presented with perianal itching and visible passage of worms (100%).

178 Perianal itching was the only side effect reported and w

179 atic recurrence, concurrent with an external perianal lesion, was detected by anoscopy.

180 genital lesions and 1 (7.7%) having a severe perianal lesion.

181 HR 2.93, 95% CI 1.68-5.12), and intergluteal/perianal lesions (HR 2.35, 95% CI 1.32-4.19).

182 V-1-negative women developed vulvovaginal or perianal lesions, resulting in an incidence of 2.6 and 0

183 and in patients diagnosed with CD only after perianal main treatment.

184 e delivery route would not alter post-partum perianal manifestations in the setting of previously hea

185 spontaneously develop terminal ileitis with perianal manifestations.

186 activity of tyrosinase in the pinnae, skin, perianal mass, and lymph nodes.

187 Conclusions and Relevance: In this study, perianal melanocytic nevi were common and were associate

188 rmine prevalence and morphologic features of perianal melanocytic nevi.

189 The prognosis of perianal melanoma is often dismal because of hidden loca

190 ures: Prevalence and morphologic features of perianal nevi according to race/ethnicity, sex, and age.

191 Perianal nevi of any size, at least 2 mm in diameter, an

192 -Hispanic whites, the presence of at least 1 perianal nevus was significantly associated with history

193 t patients with Crohn's disease and draining perianal or enterocutaneous fistulas were randomized to

194 All HSV shedding was perianal or rectal; only 1 symptomatic recurrence, concu

195 A scrotal, perianal, or anal sample should also be included for opt

196 symptomatic with anal bleeding (78 %), anal/perianal pain (63 %), weight loss (31 %) and foreign bod

197 On multivariate regression analysis perianal pain, painful defecation and weight loss were s

198 l dystrophy, scalp lesions, and intergluteal/perianal psoriasis.

199 over time (P < 0.001), and the occurrence of perianal rash and itching as well as the use of protecti

200 imaging (MRI) depicts infectious foci in the perianal region better than any other imaging modality.

201 They underwent MRI perianal region examination using routine T2 TSE and CE

202 nce standard, 3D VISTA pulse sequence on the perianal region has better diagnostic performance in the

203 17.1% at the scrotum, 33.0% at the perineal/perianal region, 42.4% in the anal canal, and 48.0% at a

204 have a thorough inspection of the vulva and perianal region, and women with abnormalities-except for

205 Pain referred to the perianal region, painful defecation and weight loss have

206 ted lesions on her abdominal wall and in the perianal region.

207 ion of the external genitalia, perineum, and perianal region.

208 mal lesions appeared on the ears, snout, and perianal regions of transgenic mice by the age of 3-4 mo

209 sampling of the penis, scrotum, and perineal/perianal regions.

210 Exclusion of urethra, semen, and either perianal, scrotal, or anal samples resulted in a <5% red

211 Perianal sensation and rectal tone were preserved.

212 On multivariate analysis, the presence of perianal sepsis (P = 0.032) and >1 medical comorbidity (

213 HPV infection at penile/scrotal and perineal/perianal sites (heterosexual men [HM] and men who have s

214 d 1.2 (.8-1.6) and 1.9 (1.5-2.4) at perineal/perianal sites, respectively; and among MSM, IP infectio

215 tunnels appearing in axillary, inguinal, and perianal skin areas.

216 was localized in the muscle layer under the perianal skin at the injection site and then diffused ou

217 ureus colonization in the nares, throat, and perianal skin on the day of enrollment and 40 days after

218 right sides of the anus of a rat through the perianal skin using 1.5mm long HM.

219 of PE into the sphincter muscle through the perianal skin with minimal pain using hollow microneedle

220 erococcosel-vancomycin broth detected VRE in perianal specimens 48 h earlier than did M-Enterococcus-

221 ancomycin-resistant enterococci and with 193 perianal specimens obtained from patients at risk in our

222 comycin-resistant enterococci (VRE) from 894 perianal stool swabs.

223 ients in the azathioprine group were free of perianal surgery than in the conventional management gro

224 ainful rectal procedure in place of ablative perianal surgery.

225 letely asymptomatic with good healing of the perianal surgical wound.

226 swab (20 of 46 versus 8 of 46; P < 0.001) or perianal swab (17 of 58 versus 12 of 58; P = 0.059) for

227 sistant Enterobacterales (FQRE) using paired perianal swab and stool specimens that were collected wi

228 a oxytoca strain 11492-1 was isolated from a perianal swab culture from a patient at the University o

229 > 256 micrograms/ml) were recovered from 66 perianal swab cultures in the enterococcosel-vancomycin

230 omycin broth, and VRE were recovered from 62 perianal swab cultures in the M-Enterococcus-vancomycin

231 Paired nasal and perianal swab samples were collected from 10 cohorts of

232 Perianal swab specimens can be collected more quickly an

233 The positive percent agreement of perianal swab specimens compared to stool specimens was

234 Nasal and perianal swab specimens were tested for detection of Sta

235 lture method for detecting VRE directly from perianal swab specimens.

236 Perianal-swab samples were obtained from 1954 of 2196 el

237 Perianal swabs are a reliable specimen type for surveill

238 45 patients had both admission and discharge perianal swabs cultured for toxigenic C. difficile.

239 A total of 40 492 admission and discharge perianal swabs from 20 246 individual patient admissions

240 tibiotic-resistant gram-negative bacteria in perianal swabs were significantly lower during SDD compa

241 Both groups had undergone MR imaging for perianal symptoms and/or systemic sepsis.

242 ultures were obtained daily from four sites (perianal, urethral, penile shaft, and oral) at home and

243 ive in the treatment of external genital and perianal warts caused by human papillomavirus (HPV).

244 e available for the treatment of genital and perianal warts; however, the topical mechanism of action

245 fe, outpatient procedure that minimizes both perianal wound creation and sphincter injury.