1 or GLP-1-stimulated insulin secretion during
perifusion.
2 nsion was recorded during continuous dynamic
perifusion.
3 ed in vivo and in isolated islets ex vivo by
perifusion.
4 RESEARCH DESIGN AND
Perifusion analyses of isolated Munc18c- (-/+) or Munc18
5 Perifusion analysis reveals that the second phase of glu
6 Islet
perifusion and calcium imaging studies showed abnormal r
7 Islet
perifusion and calcium-imaging studies showed abnormal r
8 nsulin secretion ability by in vitro glucose
perifusion and explore the expression of insulin pathway
9 Perifusion assays using pancreatic islets from transgeni
10 Further,
perifusion assays with human islets isolated from a dono
11 In islet
perifusion assays, physiologic concentrations of leucine
12 In ex vivo
perifusion assays, Smad3-deficient islets exhibit improv
13 e insulin secretion profile in dynamic islet
perifusion assays.
14 ucose-stimulated insulin release response in
perifusion assays.
15 Under
perifusion conditions, high glucose concentrations induc
16 n from islets and beta cells under static or
perifusion conditions, whereas an inactive structural an
17 glucose-stimulated insulin release in islet
perifusion experiments and have significantly reduced pa
18 Perifusion experiments indicated that cPLA(2) underexpre
19 Perifusion experiments with human islets indicated that
20 In
perifusion experiments with isolated islets in the absen
21 In
perifusion experiments, acute insulin responses (AIRs) i
22 exhibit elevated insulin release in ex vivo
perifusion experiments, during hyperglycemic clamps, and
23 In
perifusion experiments, elevations in extracellular Ca2+
24 e studied using [Ca(2+)] imaging, static and
perifusion insulin secretion assays, and gap junction pe
25 During islet
perifusions,
KIC and 2 mM glutamine caused robust dose-d
26 During local CTX + APA
perifusion,
L-NNA + INDO abolished SCVD while conducted
27 Low-Ca2+ or Ca(2+)-free
perifusion medium induced oscillatory bursting activity
28 d currents (IPSCs) were usually blocked with
perifusion of 10-50 microM bicuculline methiodide (BMI).
29 actional [3H]ACh release was recorded during
perifusion of acutely dissociated, [3H]choline-labeled,
30 However, simultaneous
perifusion of explants with ATP (100 micrometer) and PE
31 Perifusion of fatty acids restored both responses.
32 In the second experiment,
perifusion of hypothalamic slices with 10(-8) or 10(-7)
33 Perifusion of neurexin-1alpha KO mouse islets revealed a
34 In addition, ex vivo
perifusion of recovered human islet grafts demonstrated
35 Perifusion of slices with 7.5-10 mM TEA, a K+ channel bl
36 Perifusion of slices with media containing 1-2 microM TT
37 failed to induce an IDAP-like current during
perifusion of slices with media containing high [K+]o or
38 Perifusion of Syn-1A-betaKO islets showed impaired first
39 Surprisingly, insulin secretion in
perifusion or static incubation experiments in response
40 measured every 20 min during a 3-h baseline
perifusion period and after depolarization with 56 mM KC
41 functional capacity of islets as assessed by
perifusion (
r=0.60; P=0.022).
42 s was confirmed in vitro by pancreatic islet
perifusion showing an amplified biphasic glucose-stimula
43 Isolated islet
perifusion studies demonstrated that exendin-(9-39) bloc
44 Islet
perifusion studies failed to demonstrate abnormalities i
45 Perifusion studies indicate that the inhibition of [3H]p
46 e to glucose plus isobutyl-methylxanthine in
perifusion studies that is clearly larger in magnitude t
47 Perifusion studies using pharmacologic inhibitors (genis
48 ycemic clamps, as well as isolated islet and
perifusion studies.
49 A
perifusion study revealed that leptin (50 ng/ml) affecte
50 elease obtained from the same islet lot in a
perifusion system (n=12).
51 Using a
perifusion system to follow secretion over time revealed
52 rent GnRH pulse frequencies using a parallel
perifusion system.
53 The study of islets in static incubation or
perifusion systems can be informative, but the normal pa
54 ch was cut into fine slices and subjected to
perifusion to monitor glucagon release.
55 his response was not observed if the insulin
perifusion was not switched off when the islets were dep
56 Similarly, in a third experiment,
perifusion with 10(-7) M insulin caused a significant de
57 Perifusion with 16.7 mmol/l glucose plus 0.1 mmol/l IBMX
58 Perifusion with ATP before mechanical stimulation suppre
59 During local
perifusion with KCa antagonists, iberiotoxin (5 microm)
60 kade of Ca2+ release from internal stores by
perifusion with ryanodine or dantrolene, or direct diffu
61 Depletion of internal Ca2+ stores by
perifusion with thapsigargin or cyclopiazonic acid also
62 n freshly isolated mouse acinar cells during
perifusion with the bile acid taurolithocholic acid 3-su
63 ed pituitary cells and from cells undergoing
perifusion with the peptides.