ライフサイエンスコーパス: perisinusoidal

1 derate to severe collagen deposition seen as perisinusoidal and bridging fibrosis using H&E, Trichome

2 chronic ASH with macrophage inflammation and perisinusoidal and pericellular fibrosis to AH in 57% (1

3 Perisinusoidal B cells circulate freely, as revealed by

4 ich were evenly distributed in endosteal and perisinusoidal BM compartments.

5 mice reveals that quiescent Cxcl12-creER(+) perisinusoidal BMSCs differentiate into cortical bone os

6 orm to sinusoidal endothelial cells or other perisinusoidal cells, such as hepatic stellate cells, wo

7 ntiation with altered EC gene expression and perisinusoidal ECM deposition and angiocrine dysregulati

8 In ALF the perisinusoidal ECM was intact in 4 cases, collapsed or c

9 osis compared to wildtype (WT) but increased perisinusoidal elastin.

10 lls and Tcf21(+) stromal cells thus create a perisinusoidal EMH niche in the spleen, which is necessa

11 tic steatosis, substantial inflammation, and perisinusoidal fibrosis (i.e., steatohepatitis), associa

12 r and portal inflammation scores (P < 0.01), perisinusoidal fibrosis (P < 0.001), and NAS > or =5 (P

13 ic hepatosclerosis in which there is diffuse perisinusoidal fibrosis (type IV collagen) without zonal

14 ment in hepatocellular ballooning and zone 3 perisinusoidal fibrosis also occurred.

15 eration, inflammatory cell infiltration, and perisinusoidal fibrosis at age 1 month.

16 he mean steatosis (1.6 vs. 2.16, P <.04) and perisinusoidal fibrosis scores (0.35 vs. 0.9, P <.049) w

17 ne deletion in 129/Ola mice triggers hepatic perisinusoidal fibrosis that was detectable from 15 week

18 matory change was noteworthy, and by 8 weeks perisinusoidal fibrosis was established.

19 ic significance for hepatocellular function, perisinusoidal fibrosis, and portal hypertension.

20 sed on presence of steatosis, ballooning and perisinusoidal fibrosis.

21 ocyte ballooning degeneration and periportal/perisinusoidal fibrosis.

22 sive hepatocyte ballooning, and pericellular/perisinusoidal fibrosis.

23 ed on presence of steatosis, ballooning, and perisinusoidal fibrosis.

24 d by steatosis, ballooning degeneration, and perisinusoidal fibrosis; type 2 was characterized by ste

25 Because LPS-stimulated perisinusoidal hepatic stellate cells (HSCs) produce cyt

26 d, it is now apparent that the activation of perisinusoidal hepatic stellate cells, which is a key ev

27 f was primarily expressed by endothelial and perisinusoidal hepatic stellate cells.

28 oid progenitors were closely associated with perisinusoidal LepR(+) cells.

29 sponsible for sinusoidal capillarization and perisinusoidal matrix deposition, impairing vascular exc

30 ied in PCE in ARLD biopsies and broken dense perisinusoidal mature elastic fibres in explanted livers

31 ing CXCR4-CXCL12-dependent migration towards perisinusoidal megakaryocytes, plucking neutrophils acti

32 One model suggests that perisinusoidal mesenchymal stem cells (MSCs) give rise t

33 IgD(hi) B cells can occupy an extravascular perisinusoidal niche in the bone marrow in addition to t

34 py an anatomically and functionally distinct perisinusoidal niche in the bone marrow.

35 ations of the aged HSC niche and unveil that perisinusoidal niches are uniquely preserved and thereby

36 and non-dividing HSCs thus reside mainly in perisinusoidal niches with Lepr(+)Cxcl12(high) cells thr

37 from NG2(+) periarteriolar niches to LEPR(+) perisinusoidal niches.

38 d cellular polarity, reside predominantly in perisinusoidal niches.

39 circulating monocytes transmigrated into the perisinusoidal space and acquired the liver-associated t

40 thin the metaphysis of long bones not in the perisinusoidal space and are needed for bone development

41 Located within the perisinusoidal space and surrounded by extracellular mat

42 onectin in normal liver was localized to the perisinusoidal space surrounding the periportal and the

43 brinogen in normal liver is localized to the perisinusoidal space surrounding the periportal region.

44 The perisinusoidal stellate cells of the liver in an injury

45 in the liver is activation and migration of perisinusoidal stellate cells.

46 ibited endothelin-1-induced contractility of perisinusoidal stellate cells.

47 epatic stellate and endothelial cells create perisinusoidal vascular HSC niche in the developing live