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1 ed by GluA4 subunits should be highly Ca(2+) permeable.
2 effects, suggesting that hPL is not membrane-permeable.
5 reclinical mouse studies suggested that cell-permeable aKG displays a good biosafety profile, elimina
6 m for the metabolite aKG and identifies cell-permeable aKG, either by itself or in combination with E
7 eurons augments dentate granule cell calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazoleprop
8 ee cells was rescued with exogenous membrane-permeable alpha-ketoglutarate, but not pyruvate or oxalo
10 its permeation through Ca(2+)- (and Zn(2+))-permeable AMPA channels in CA3 and Zn(2+) mobilization f
12 echanisms akin to Hebbian plasticity: Ca(2+)-permeable AMPA receptor upregulation, L-type Ca(2+) chan
13 rawal from this regimen; furthermore, Ca(2+)-permeable AMPA receptors (CP-AMPARs) increase in the NAc
14 h an accumulation of high conductance Ca(2+)-permeable AMPA receptors (CP-AMPARs) that is detectable
15 possible involvement of GluA2-lacking Ca(2+)-permeable AMPA receptors (CP-AMPARs) using IEM-1460, whi
16 its induction but, instead, requires Ca(2+) -permeable AMPA receptors and group I metabotropic glutam
21 reversal of alcohol-induced insertion of Ca-permeable AMPARs and the enhancement of glutamatergic ac
22 on, and increased the contribution of Ca(2+)-permeable AMPARs to the overall glutamatergic response.
23 IEM-1460, an open channel blocker of Ca(2+)-permeable AMPARs, we propose a novel method to determine
25 oyl-1-acetyl-sn-glycerol (OAG), the membrane-permeable analog of diacylglycerol, were not defined.
27 at was accompanied by an increase in calcium-permeable and calcium-impermeable AMPARs, respectively.
29 that this 90-amino acid mini-protein is cell permeable and can inhibit proliferation of Myc-dependent
30 on selectively rendered tumor vessels highly permeable and caused massive intratumoral hemorrhage.
32 synthesis and evaluation of a series of cell-permeable and N- versus O-selective sialyltransferase in
33 yclized from head to tail, like the membrane permeable and orally bioavailable natural product cyclos
35 t of transport, we localize the PVM nutrient-permeable and protein export channel EXP2, as well as th
36 be useful in live cells, probes must be cell permeable and provide a read-out that can be measured wi
38 residues, given that these agents were cell permeable and stable in aqueous buffer and in plasma.
39 y rats confirmed that both compounds are BBB permeable and that bladder accumulation is low until at
40 n vivo mice studies, the probe is safe, cell permeable, and capable of producing a "turn-on" luminesc
41 ZP4-null ZP was significantly thinner, more permeable, and exhibited a more disorganized and fenestr
42 activity profiles of GSK789, a potent, cell-permeable, and highly selective inhibitor of the first b
43 hod enabled the production of free-standing, permeable, and highly transparent MMMs which showed enor
45 ort the development of a highly potent, cell-permeable, and metabolically stable peptidyl inhibitor,
47 pidly identifying synthetic, miniature, cell-permeable, and reversible inhibitors against both SpCas9
48 wed generation of 31 (GSK6776) as a soluble, permeable, and selective BRD7/9 inhibitor from a pyridaz
51 e, the PDZ forms a transient, size-dependent permeable barrier to protect the embryo from maternal ci
53 al oil degradation in the tidally ventilated permeable beach sand, emphasizing the role of the sandy
55 n, the various strategies for designing cell-permeable, biologically active cyclic peptides against i
57 In human pancreatic adenocarcinoma, poorly-permeable blood vessels limit the intratumoral permeatio
59 stapled peptides can be rendered highly cell-permeable by conjugating a cyclic cell-penetrating pepti
60 muscle cells (VMSCs), stimulation of Ca(2+) -permeable canonical transient receptor potential channel
62 nel subfamily A member 1 (TRPA1) is a Ca(2+)-permeable cation channel that serves as one of the prima
63 n member 8 (TRPM8) is a calcium ion (Ca(2+))-permeable cation channel that serves as the primary cold
64 ass of NAADP- and PI(3,5)P2-sensitive Ca(2+)-permeable cation channels in the endolysosomal system of
66 a mechanically-activated nonselective Ca(2+) permeable cationic channel in a range of mammalian cells
67 potential melastatin 2 (TRPM2) is a calcium-permeable channel activated by adenosine diphosphate rib
68 owed that GLR3.3 and GLR3.6 displayed Ca(2+)-permeable channel activities gated by both glutamate and
69 re-forming protein required for the nutrient-permeable channel activity and protein export at the PVM
71 dly, loss of EXP1 affected only the nutrient-permeable channel activity of the PVM but not protein ex
72 one isoform, AtMCU1, gives rise to a Ca(2+)-permeable channel activity that can be observed even in
73 unctional expression of EXP2 as the nutrient-permeable channel and is critical for the metabolite sup
75 ted that the proper recruitment of the water-permeable channel aquaporin-4 (AQP4) to astrocytic endfe
76 tial canonical channel-1 (TRPC1) is a Ca(2+)-permeable channel found in key metabolic organs and tiss
78 report that the Arabidopsis thaliana Ca(2+)-permeable channel OSCA1.3 controls stomatal closure duri
79 ions as a hyperpolarization-activated Ca(2+)-permeable channel specifically regulating bak1/serk4 cel
80 (ANN1), which was reported to form a calcium-permeable channel that contributes to the NaCl-induced [
81 aling, Thakore et al. report that the Ca(2+)-permeable channel TRPML1 closely associates with ryanodi
83 dilation model, ATP binding opens an NMDG(+)-permeable channel within milliseconds, with a conductanc
86 nucleus, we targeted expression of a Ca(2+)-permeable channelrhodopsin (CatCh) specifically to tanyc
87 knowledge of regulation of tonoplast Na(+) -permeable channels and discusses the energy cost of vacu
89 thyl-d-aspartate (NMDA) receptors are Ca(2+)-permeable channels gated by glutamate and glycine that a
90 he expression and function of various Ca(2+)-permeable channels in the plasma membrane, endoplasmic r
92 w that GLR genes encode non-selective Ca(2+)-permeable channels that can regulate cytoplasmic Ca(2+)
93 hat they are voltage-gated Na(+)- and Ca(2+)-permeable channels, with rapid kinetics resembling metaz
97 notropic receptors mediating a slow, calcium-permeable component of excitatory synaptic transmission
98 n ion channel that mediates the slow, Ca(2+)-permeable component of glutamatergic synaptic transmissi
101 alinity to permeability heterogeneity due to permeable conduits and normal faults, and to recharge fr
103 VAE cohort) with and without their Rigid Gas Permeable contact lenses (RGP CL's) and 20 age-matched c
104 o inwardly rectifying, GluA2-lacking, Ca(2+)-permeable (CP) AMPARs on time scales ranging from minute
106 , using CSD mutants (F92A/V94A) and membrane-permeable CSD-competing peptides, that Src kinase-depend
107 g-chain acyl-coenzyme A synthetase2 (lacs2), permeable cuticle1 (pec1), cyp77a6, glycerol-3-phosphate
108 phosphodiesterase 3B (PDE3B), and a membrane-permeable cyclic guanosine monophosphate (cGMP) analog o
110 ipulating actin dynamics are limited to cell-permeable drugs that preclude single-cell perturbations.
111 nt epithelium and endothelium, embedded in a permeable ECM, and independently addressed using a close
112 n signaling leads to a partial conversion of permeable endothelial cells to a barrier-type state.
122 e often related to fluid injection into deep permeable formations that are hydraulically connected to
124 ified brine at high rates resulted in a more permeable fractured media in comparison to the case with
125 ts on both cell volume homeostasis and Cl(-)-permeable GABAA receptor-dependent membrane excitability
126 act as positive modulators of chloride (Cl-) permeable GABAA receptors, are indicated as first-line t
133 olar versus micromolar sensitivity to a cell-permeable GSi (Z-LLNle-CHO) across 60 diverse tumor line
135 of improving water flux by developing highly permeable, highly selective membranes may not be realist
138 emonstrated by incorporating 1.Eu into water-permeable hydrogels that can be utilized as an alternati
139 general approach for the development of cell-permeable inhibitors of thioester-forming E3 ubiquitin l
140 xpression, yet there are few selective, cell-permeable inhibitors or suitable tool compounds for thes
141 ght junction formation on both coverslip and permeable inserts, in addition to enhancing and maintain
143 ation of the mechanically activated, calcium-permeable ion channel Piezo1 in the pancreatic acinar ce
144 astatin member 8 (TRPM8), which is a calcium-permeable ion channel, functions as the primary molecula
145 ations in the gene encoding TRPM3, a calcium permeable ion channel, were identified as the cause of D
146 The role of mechanosensitive (MS) Ca(2+)-permeable ion channels in platelets is unclear, despite
147 mance improvement by incorporation of highly permeable ionomers as the functional catalyst binder.
148 hich sets the driving force for the chloride-permeable ionotropic GABAA receptor in mature neurons.
149 ellular free iron content using the membrane-permeable iron chelator 2,2'-dipyridyl effectively remov
151 ation of KG can treat Ndufs4-KO mice, a cell-permeable KG, dimethyl ketoglutarate (DMKG) was administ
152 th; we interpret that the reservoirs share a permeable, laterally extensive, and hydraulically connec
153 and shear stress profiles for flow over the permeable layer for the limiting cases of alpha --> 0 an
157 ct lens use in the past 2 weeks or rigid gas-permeable lens wear within 4 weeks, history of prior ocu
159 eat domain forms highly dynamic, mesoscopic, permeable, liquid-like droplets possessing rapid interna
160 ng glucosylceramide, colonoids become highly permeable, lose structural integrity, and eventually bur
161 em-cell conditions, we demonstrate that cell permeable MARCKS effector domain (ED) peptides potently
162 stem distinguishes opaque surfaces and light-permeable materials and why discrepancies arise between
163 ptor potential vanilloid 4 (TRPV4), a Ca(2+)-permeable mechanosensitive cation channel in the transie
164 at an oil-water interface to produce a semi-permeable membrane between the liquids, and from them al
166 component of the plug (Film) is a stitchable permeable membrane consisting of polycaprolactone (PCL)
167 ) can be efficiently removed via another gas permeable membrane device permitting detection of the el
168 force distance curves also exhibited a more permeable membrane for CYnLIP-incubated skin than hydrat
170 y diffusing an acidic oil solution through a permeable membrane in a 2-layer microfluidic device, thu
171 usher in an alternative design paradigm for permeable membrane materials in separations, energy prod
172 r leads to opening of the characteristic dye-permeable membrane pore for molecules up to 900 Da.
174 croporous polytetrafluoroethylene (PTFE) gas-permeable membrane was utilized for the first time to de
175 hielded by an ultrathin layer of a potassium-permeable membrane, which prevents diffusion of other ca
179 nting engineered self-patterning bacteria on permeable membranes that serve as a structural scaffold.
180 oatings and the covalent bonding of the semi-permeable membranes with biocompatible crosslinkers such
184 age (5 day old) was characterized by a more permeable mucus layer relative to 21 day old pups, sugge
185 These compounds emerge as interesting brain-permeable multitarget compounds, with a potential as ant
186 Bleeding and vascular complications, using permeable nitinol cardiac occluders to close the access
187 r Potential Melastatin 3 (TRPM3) is a Ca(2+) permeable non-selective cation channel activated by heat
189 Canonical 5 (TRPC5) is a subunit of a Ca(2+)-permeable non-selective cationic channel which negativel
190 receptor potential mucolipin 1) is a Ca(2+)-permeable, nonselective cation channel localized to the
191 receptor potential mucolipin 1) is a Ca(2+)-permeable, nonselective cation channel that is predomina
192 ction, we developed inhibitors that are cell permeable, nontoxic, and selectively bind to the inactiv
193 rs, including those able to desensitize, are permeable not only to NMDG(+) but also to spermidine, a
194 ntroduce a novel use for blood-brain barrier-permeable NOX inhibitor with a significant potential to
195 ed studies show that treatment with the cell-permeable nucleoside counterpart of 5-MeCITP leads to te
196 torage facilities, type of packaging (oxygen-permeable or not), and premix composition (with or witho
197 In this study, we developed a nontoxic cell-permeable ORF45-derived peptide from the RSK-binding reg
198 selective bioorthogonal reaction with a cell-permeable organic dye enables live cell imaging of micro
202 tion of the CFTR/CAL interaction with a cell-permeable peptide improves the function of rescued F508d
203 s in cell lines and in vivo using small cell-permeable peptides confirms that the endogenous intracel
205 hypoxia (0.1% O(2); 24 h), the BBB was more permeable, permitting the uptake of more nanoparticles a
206 we locally applied arachidonic acid and skin-permeable peroxide by micropipette perfusion to unwounde
209 enic peptide nucleic acid probes embedded in permeable, physically crosslinked, alginate beads were a
211 well spheroid culture devices made of oxygen-permeable polydimethylsiloxane (PDMS), with which hypoxi
212 n the cell surface was encapsulated within a permeable polyethylene glycol diacrylate (PEGDA) hydroge
213 cal properties for CO(2) sorption within gas-permeable polymer shells, creating Micro-Encapsulated CO
214 oluble polymethyloxazoline shells and oxygen-permeable polystyrene cores crosslinked with metal-free
215 tuted into liposomes, forms an intrinsic dye-permeable pore in the absence of other cellular componen
218 ns (eg, claudin-4) as receptors to form Ca2+-permeable pores in the membrane, damaging epithelial cel
219 reflects an interplay among multiple Ca(2+) permeable pores with distinct electrophysiological prope
220 Our results showed that photocaged cell-permeable probe represents a valuable new tool for achie
222 o166 to a small molecule produced a membrane-permeable probe that reported the localization of the DN
226 enzymatic core encapsulated in a selectively permeable protein shell; prominent examples include the
228 ith a cell-penetrating entity yielded a cell-permeable proteomimetic that activates cell proliferatio
232 t is rapidly metabolized and poorly membrane permeable, restricting its use to intratumoral administr
233 as9 (SpCas9) that weigh <500 Da and are cell permeable, reversible, and stable under physiological co
234 ial separation between anammox and n-damo in permeable riverbed sediments that potentially avoids the
238 tic charges from solid objects, indicating a permeable sensor or charge filter for electronic applica
239 ly, sialic acid supplementation using a cell-permeable sialic acid analogue (Ac(5)Neu5Ac) boosted GD2
240 n is based on an efficient control of Na(+) -permeable slow- and fast-vacuolar channels that mediate
241 velopment of DI-591 as a high-affinity, cell-permeable small-molecule inhibitor of the DCN1-UBC12 int
243 relaxation kinetics depends on the number of permeable species; 2) the permeability coefficients (P)
245 muscle cells (VSMCs), activation of Ca(2+) -permeable store-operated channels (SOCs) composed of can
246 lease could be through stimulation of Ca(2+) permeable stretch activated channels, we hypothesised a
247 l membrane must be a dynamic and selectively permeable structure to enable bidirectional and differen
248 The OM and PG are load-bearing, selectively permeable structures that are stabilized by cooperative
250 tinal epithelia using enteroid monolayers on permeable supports (such as Transwells) represents an al
251 nes, representing six species, were grown on permeable supports under conditions specific for the res
257 one-methiodide was found to be ~40-fold less permeable than naloxone-HCl across the blood-brain barri
260 tial vanilloid 3 (TRPV3) channel is a Ca(2+)-permeable thermosensitive ion channel widely expressed i
261 Our results show that the reptile fence is permeable throughout at those points where the metal she
263 a(2+) exchange to an uncoupled channel mode, permeable to both Ca(2+) and Mn(2+) The findings in our
264 icantly stabilizes the SF in a state that is permeable to both K(+) and Na(+), which is reminiscent o
266 trophysiological data reveal that OSCA1.3 is permeable to Ca(2+), and that BIK1-mediated phosphorylat
267 vanilloid subfamily of TRP channels that is permeable to cations and highly selective to Ca(2+) ; it
271 X7 receptors, two-transmembrane ion channels permeable to Na(+), K(+), and Ca(2+) Receptor activation
273 y the BBB is disrupted to the point of being permeable to normally non-penetrant agents without causi
274 tochondrial membrane becomes depolarized and permeable to osmolytes, proposedly due to the opening of
279 and hexagonal boron nitride are surprisingly permeable to thermal protons, despite being completely i
280 ed using standard preparations are passively permeable to various hydrophilic solutes as large as 40
281 acromolecules in contact with pores that are permeable to water and ions but not macromolecules.
283 al assessment of cellular coupling with a GJ-permeable tracer Neurobiotin to determine distribution p
284 an central nervous system by forming calcium-permeable transmembrane channels upon binding glutamate
286 mediated by phospholipase C (PLC) and Ca(2+)-permeable TRP channels, but the function of endoplasmic
289 act HeLa cells using the new photocaged cell-permeable ubiquitin probe and identified DUBs captured b
295 chip experiments involving particles and gas-permeable walls and help understand similar configuratio
296 curs in a common-flow configuration with gas-permeable walls, but in the absence of any installed sou
297 rticles is driven by the gas leakage through permeable walls, which is induced by the pressure differ
298 an be achieved by having gas leakage through permeable walls, without any preimposed ion-concentratio
299 perience, GluA2-lacking AMPARs, which are Ca permeable, were inserted into vHipp to D1-MSN synapses.
300 th the anionic ligand pyrithione is membrane permeable, which circumvents the need to utilize invasiv