ライフサイエンスコーパス: permease

1 ransfer it to its cognate inner membrane ABC permease.

2 on and encode a putative membrane-associated permease.

3 on protein, YknY is an ATPase, and YknZ is a permease.

4 activity with the broad specificity mannose permease.

5 phosphate-binding cassette (ABC) transporter permease.

6 receptor, ComR, after uptake by oligopeptide permease.

7 ular hinge between the two halves of lactose permease.

8 ne is located in a hydrophobic region of the permease.

9 ve structural model based on E. coli lactose permease.

10 scriptional repressor of the NikABCDE nickel permease.

11 he cytoplasm from the periplasm via the AmpG permease.

12 facilitator transporter superfamily, lactose permease.

13 T456S and S176N convert Can1 to a Lyp1-like permease.

14 romise with suboptimal activity for most PTS permeases.

15 endent sugar:phosphotransferase system (PTS) permeases.

16 membrane domain protein with homology to ion permeases.

17 cells with a small number of membrane-bound permeases.

18 n of not only Trk1 but also several nutrient permeases.

19 f the nutrient scavenging general amino acid permease 1.

20 The Ureide Permease 5 (UPS5) is expressed in the cortex and endoder

21 AtUPS5 (Arabidopsis UREIDE PERMEASE 5) is a transmembrane protein that transports a

22 scherichia coli PTR dipeptide and tripeptide permease A (DtpA), which shows substrate specificities s

23 the five annotated homologs of oligopeptide permease A (OppA5, BBA34).

24 ermease (biofilm and endocarditis-associated permease A [BepA]), as important in infective endocardit

25 ansport ability of nine tea plant amino acid permease (AAP) family members, with six exhibiting trans

26 Amino acid permeases (AAPs) in the plasma membrane (PM) of Saccharo

27 M. catarrhalis has a putative oligopeptide permease ABC transport operon (opp) consisting of five g

28 hreshold, and abolishes bistability at large permease activities, a conclusion that can be tested exp

29 Potassium, but not chloride, permease activity required the presence of calcium ions

30 the lac operon that minimize the cost of lac permease activity, not protein expression.

31 Instead, we discovered that the lac permease activity, which relates linearly to cost, is th

32 anine biosynthesis and identified an alanine permease, AlaP (YtnA), which we show has a major role in

33 of the cel regulon, but loss of specific PTS permeases alleviated repression of cel genes in the pres

34 ion of STOP1 targets, including the membrane permease ALMT1, to increase malate exudation in response

35 s, a defect in the trafficking of the uracil permease, alpha-syn accumulation and foci, and a slow gr

36 idis recycles PG fragments via the selective permease AmpG and that meningococcal PG recycling is mor

37 tinct domains: a membrane-anchored metal ion permease and a diphtheria toxin repressor (DtxR)-like tr

38 osine and uridine uptake mediated by the NT1 permease and also induced up to a 200-fold enhancement i

39 All LIV permease and ATPase components were dispensable for in v

40 dentify these proteins, mutants of candidate permease and ATPase genes were generated allowing for ch

41 results provide the first description of the permease and ATPase proteins required for the import of

42 cus tag: SO_1522-SO_1518) containing lactate permease and candidate genes for both d- and l-lactate d

43 Mutants lacking the FpuB permease and FatE ATPase (DeltafpuBDeltafatE) and a muta

44 incided with a reduction in putative sulfate permease and not sulfate adenylyltransferase transcripts

45 thway (sugar-phosphotransferase system [PTS] permease and sucrose-6-PO(4) hydrolase) constitute the m

46 notype with the activity of the auxin intake permease and suggests that MED12 acts upstream of AUX1 i

47 ligand-binding component of an ABC-type zinc permease and that perturbation of zinc homeostasis inhib

48 FsrA also represses the DctP dicarboxylate permease and the iron-sulfur-containing enzyme glutamate

49 ndocytosis by interacting with both a client permease and the ubiquitin ligase Rsp5.

50 for a heterodimeric pair of ABC transporter permeases and may code for part of a new pathway for syn

51 consists of ddT transport by host nucleoside permeases and phosphorylation to ddTMP by the host thymi

52 ese data, a model for the involvement of PTS permeases and the general PTS proteins enzyme I and HPr

53 ed lipid transporter consisting of the TGD1 (permease) and TGD3 (ATPase) proteins.

54 the inducer enters the cell via the carrier (permease), and exits by a diffusion-like process.

55 , arsP that encodes the ArsP MAs(III) efflux permease, and arsH encoding the ArsH MAs(III) oxidase.

56 ogic machines, such as ATP synthase, lactose permease, and G-protein-coupled receptors.

57 t encodes a ferric hydroxamate uptake system permease, and propose that the norA transcription is iro

58 nnose family phosphotransferase system (PTS) permease, and we designate the genes encoding the permea

59 ed by well studied xanthine and/or uric acid permeases, and COG2252, consisting of transporters for a

60 imensional structure exists for any of these permeases, and they are not present in prokaryotes, the

61 topology, stability and function of lactose permease are found to have different dependences on bila

62 These permeases are known to positively affect sporulation in

63 ox because five putative carbohydrate uptake permeases are present in Mtb, but there are essentially

64 Interestingly, TbPT family permeases are related to polytopic proteins from plants

65 that regulates the expression of amino acid permeases, are impaired in multiple aspects of fungus-ma

66 A bacterial permease, ArsP, from Campylobacter jejuni, was recently

67 athway of Gap1 down-regulation targets other permeases as well, and it likely allows cells facing adv

68 hal5 growth defects by stabilizing nutrient permeases at the plasma membrane.

69 f unknown function adjacent to the canonical permease, ATPase, and solute-binding protein (SBP) genes

70 two-hybrid analyses and could show that the permease BceB and the histidine kinase BceS interact dir

71 analyzed substrate binding by the transport permease, BceB.

72 Permeases belonging to the equilibrative nucleoside tran

73 Therefore, we propose that the PTS permease BepA is directly implicated in E. faecium patho

74 fined nonpolar mutants of the beta-glucoside permease (bglP) and beta-glucosidase enzyme (bglB) in 54

75 carbohydrate phosphotransferase system (PTS) permease (biofilm and endocarditis-associated permease A

76 ly of nine homologs designated as BIA uptake permeases (BUPs).

77 roposal that HPr is not optimal for most PTS permeases but instead represents a compromise with subop

78 se permease (MelB), supporting the idea that permeases can differ in their thermodynamic response to

79 ificity of the H(+)-driven arginine-specific permease Can1.

80 nd to iron limitation by expressing the iron permease CgFtr1 primarily on the cell membrane, and to i

81 e ATPase(s) interacting with each individual permease channel.

82 s: SmbF (the ATPase component) and SmbT (the permease component).

83 ng the permease dgaABCD (d-glucosaminate PTS permease components EIIA, EIIB, EIIC, and EIID).

84 Deletions of Hup permease components hupD, hupG or hupDGC reduced Hn/Hb u

85 uired the binding protein and inner membrane permease components of its overall transport system; pos

86 genome neighborhoods encoded SBPs as well as permease components of the TRAP transporters, members of

87 Members of the Acr3 family of arsenite permeases confer resistance to trivalent arsenic by extr

88 nally, we show for the first time that HrtBA permease controls heme toxicity by its direct and specif

89 hat we tested, the expression of the lactose permease could be costly or beneficial, depending on the

90 r data establish that bbb22-23 encode purine permeases critical for B. burgdorferi mammalian infectiv

91 Herein, TM organization of sucrose permease (CscB) and phenylalanine permease (PheP) as a f

92 Expression of AUX1 in a permease-deficient vat3 mutant resulted in increased net

93 erse conditions to retrieve amino acids from permease degradation.

94 A mutant strain lacking both permeases, DeltafpuBDeltafatCD, was incapable of using p

95 Potentially similar ammonium permease-dependent regulatory cascades operate in other

96 ase, and we designate the genes encoding the permease dgaABCD (d-glucosaminate PTS permease component

97 Moreover, the unusual membrane permease-DNA-binding polypeptide fusion configuration wa

98 er SYG1, Pho81 and XPR1) domain and an anion permease domain.

99 cells maintained in rich media and nutrient permease downregulation in yeast.

100 Furthermore, cell-free synthesis of lactose permease during DIB formation also results in active tra

101 ecific sugar phosphotransferase system (PTS) permease (EII(Cel)).

102 The glucose- and lactose-PTS permeases, EII(Man) and EII(Lac), respectively, were sho

103 idase (GenA) and a phosphotransferase system permease EIIC (GenB).

104 ional mutant library of all 14 annotated PTS permease (EIIC) genes in MGAS5005, the annotated beta-gl

105 tansenzyme II (EII(Lev)), a fructose/mannose permease encoded by the levDEFG genes, and fruA, which e

106 repressor from DNA result in large bursts of permease expression that trigger induction of the lac op

107 As a membrane permease, Fcy2 may mediate limited cisplatin transport b

108 gh both hephaestin (Hp) and the ferrous iron permease ferroportin (Fpn) have been identified in BMVEC

109 sphatidylethanolamine lipids, lowers lactose permease folding and reconstitution yields but stabilise

110 rter for fructose (Frt), a major facilitator permease for glucose (GlcP), and a porin needed for the

111 ty and subsequently release it to a membrane permease for translocation into the cytoplasm.

112 Four encoded putative transporters or permeases for gamma-amino acids or drugs.

113 is and showed that they encode high affinity permeases for the uptake of adenine (PurP and YicO) or g

114 Either of two distinct permeases, FpuB or FatCD, is required for iron acquisiti

115 Crystal structures of lactose permease from Escherichia coli (LacY) exhibit two six-he

116 tures of both a mutant and wild-type lactose permease from Escherichia coli (LacY) in an inward-facin

117 f the NCS1 family, the Mhp1 benzyl-hydantoin permease from Microbacterium liquefaciens, allowed us to

118 r such a transporter, the LdNT1.1 nucleoside permease from the parasitic protozoan Leishmania donovan

119 r such a transporter, the LdNT1.1 nucleoside permease from the parasitic protozoan Leishmania donovan

120 is generally accomplished by arsenite efflux permeases from Acr3 or ArsB unrelated families.

121 ity with the glycerol-3-phosphate and fucose permeases from Escherichia coli, respectively.

122 ecificity towards Fe(2)(+) and a ferric iron permease, Ftr1p, which supports Fe-accumulation.

123 mmetry motifs in the Escherichia coli fucose permease (FucP) results in remarkable homology to lactos

124 organic Pi transporter, Glycerol-3-phosphate permease (G3Pp) family, comprising five members (AtG3Pp1

125 replaced by increased expression of the GalP permease (galP) and glucokinase (glk).

126 Galactose permease (GalP) is the closest bacterial homolog of huma

127 For instance, the general amino acid permease Gap1 transports all amino acids, whereas Can1 a

128 racellular sorting of the general amino acid permease Gap1.

129 The high capacity general amino acid permease, Gap1p, in Saccharomyces cerevisiae is distribu

130 llular trafficking of the general amino acid permease, Gap1p, of Saccharomyces cerevisiae is regulate

131 for RNA-sequencing and the fluoride related permease gene (frtP) was found as 1 of the downstream ge

132 The high affinity iron permease gene (FTR1) is required for R. oryzae iron tran

133 esis in Staphylococcus aureus, the glutamine permease gene (glnP) was inactivated and TCA cycle activ

134 ng lytA (the major autolysin gene) and piaB (permease gene of the pia ABC transporter) are currently

135 A deletion of the permease gene scfD resulted in a monoculture growth defe

136 repressing the adjacent phosphate-responsive permease gene transporter for glycerophosphodiester 1 (t

137 lncRNA transcription upstream of the tgp1(+) permease gene.

138 polycistronic with the upstream oligopeptide permease genes (opp1ABCDF), which encode an ABC oligopep

139 G, argH and argJ) and two arginine/histidine permease genes (SSA_1568 and SSA_1569) were upregulated

140 and rafEFG (raffinose substrate binding and permease genes), and both glucose and sucrose inhibited

141 unced for the highly expressed NCR-regulated permease genesGAP1,MEP2,DAL5,PUT4, andDIP5 Our results r

142 tional analyses, we identified the glutamine permease, GNP1 as a specific transporter for theanine in

143 sence of a heterologous plasma membrane heme permease (HRG-4), but the mode of suppression mediated b

144 ng of another gene involved in resistance, a Permease-I like protein, did not affect the expression o

145 ined the topological organization of lactose permease in an Escherichia coli model cell system in whi

146 he first evidence of an intracellular purine permease in apicomplexan parasites and suggests a novel

147 of the YtgR domain from a membrane-anchored permease in C. trachomatis could represent a previously

148 eisseria spp., the importance of the lactate permease in colonization of the host has been demonstrat

149 transporter 1.1 (LdNT1.1) that captured this permease in the outward-closed conformation, and we iden

150 teria, we discovered that inactivating these permeases in C. difficile resulted in the earlier expres

151 ing necessary for transport catalysed by MFS permeases in general.

152 components, and certain fructose/mannose-PTS permeases in the transcriptional regulation of the cel l

153 ular sorting of Gap1, the general amino acid permease, in response to nutrients.

154 IIA(Glc) is a negative regulator for several permeases, including the maltose transporter MalFGK2.

155 Facilitator Superfamily transporter, lactose permease, into Droplet Interface Bilayers and demonstrat

156 ransduction proteins, metabolic enzymes, and permeases involved in nitrogen assimilation.

157 transduction proteins, metabolic enzymes, or permeases involved in nitrogen metabolism.

158 Lactose permease is a paradigm for the major facilitator superfa

159 It is believed that sugar binding to the permease is involved in an induced fit mechanism, and th

160 tant defective in a putative ABC transporter permease is resistant to both streptococcus/nitrite- and

161 y depleting glucose from the medium, and the permease is strongly down-regulated when flagellated ins

162 Therefore, the topology of both permeases is dependent on PE.

163 Gap1, the yeast general amino acid permease, is a convenient model for studying how the int

164 odel membrane protein (the bacterial lactose permease LacY reconstituted in proteoliposomes) and a co

165 The lactose permease (LacY) catalyzes coupled stoichiometric symport

166 The lactose permease (LacY) catalyzes galactoside/H(+) symport via a

167 x bundles on the periplasmic side of lactose permease (LacY) cause complete loss of transport activit

168 ty (K(d)(app)) of purified wild-type lactose permease (LacY) for sugars was studied.

169 gy-independent downhill transport by lactose permease (LacY) is impaired when expressed in Escherichi

170 N-terminal half of Escherichia coli lactose permease (LacY) is inverted with respect to the C-termin

171 The lactose permease (LacY) of Escherichia coli catalyzes stoichiome

172 In vivo lactose permease (LacY) of Escherichia coli displays a mixture o

173 Lactose permease (LacY) of Escherichia coli is an archetypal mem

174 The lactose permease (LacY) of Escherichia coli, a paradigm for the

175 Lactose permease (LacY) of Escherichia coli, when reconstituted

176 Based on the crystal structure of lactose permease (LacY) open to the cytoplasm, a hybrid molecula

177 X-ray crystal structures of lactose permease (LacY) reveal pseudosymmetrically arranged N- a

178 Sugar/H(+) symport by lactose permease (LacY) utilizes an alternating access mechanism

179 Lactose permease (LacY), a paradigm for the largest family of me

180 Lactose permease (LacY), a paradigm for the largest family of me

181 of Escherichia coli is catalyzed by lactose permease (LacY), which uses an alternating access mechan

182 P) results in remarkable homology to lactose permease (LacY).

183 s to a plant-specific class of purine uptake permease-like transporters that originated after the bry

184 ed for expression of genes encoding a malate permease (maeP) and malic enzyme (maeE).

185 from their primary role in nutrition, these permeases may help Devosia to sense environmental signal

186 Further, the Sap translocator permease mediated heme transport into the bacterial cyto

187 The bacterial melibiose permease (MelB) belongs to the glycoside-pentoside-hexur

188 Melibiose permease (MelB) is one among several permeases subject t

189 ITC differs from the inhibition of melibiose permease (MelB), supporting the idea that permeases can

190 he ammonium transporter (AMT)/methylammonium permease (MEP)/Rhesus glycoprotein (Rh) family of ammoni

191 Ammonium transporters (AMT), methylamine permeases (Mep), and the more distantly related rhesus f

192 The ammonium permease Mep2 is required for the induction of pseudohyp

193 he peptide transporter Ptr2 and the ammonium permease Mep3 as Syp1 cargoes containing DxY motifs.

194 ibe the details known for examples of uptake permeases, metallochaperones and proteins involved in me

195 ells is mediated by about 16 plasma membrane permeases, most of which belong to the amino acid-polyam

196 ent the molecular features in the methionine permease Mup1 that are required for Art1-Rsp5-mediated u

197 the presence of fucose, although its fucose permease mutant (fucP) shows no change.

198 Pase mutants were generated in either of the permease mutant backgrounds to identify the ATPase(s) in

199 dies using E. coli or C. glutamicum arsenite permease mutants clearly show that CgAcr3-1 is specific

200 he DeltascfC substrate-binding and DeltascfD permease mutants, but not the DeltascfE ATPase mutant, w

201 To study the roles of the four purine permeases NT1-NT4 in Leishmania major, null mutants in e

202 iana tabacum gene encoding a nicotine uptake permease (NUP1).

203 d through a crystal structure of the lactose permease of E. coli (LacY), manually adjusted, and energ

204 The lactose permease of Escherichia coli (LacY) is a highly dynamic

205 The lactose permease of Escherichia coli (LacY) is a highly dynamic

206 lines of evidence indicate that the lactose permease of Escherichia coli (LacY) is highly dynamic an

207 WT lactose permease of Escherichia coli (LacY) reconstituted into p

208 nt (Gly46-->Trp/Gly262-->Trp) of the lactose permease of Escherichia coli (LacY) with a bound, high-a

209 Lactose permease of Escherichia coli (LacY) with a single-Cys re

210 enesis, insertion and folding of the lactose permease of Escherichia coli (LacY), a 12-transmembrane

211 The lactose permease of Escherichia coli (LacY), a highly dynamic me

212 The lactose permease of Escherichia coli (LacY), a highly dynamic po

213 ed for sugar-binding affinity to the lactose permease of Escherichia coli (LacY), indicating that, un

214 The melibiose permease of Escherichia coli (MelB) catalyzes the couple

215 We previously established that lactose permease of Escherichia coli displays a mixture of topol

216 -transmembrane domain (TM) bundle of lactose permease of Escherichia coli is uniformly inverted when

217 the galactoside/H(+) symporter LacY (lactose permease of Escherichia coli) are irreplaceable for an a

218 X-ray crystal structures of LacY (lactose permease of Escherichia coli) exhibit a large cytoplasmi

219 The melibiose permease of Salmonella enterica serovar Typhimurium (Mel

220 tal structure of the Na(+)-coupled melibiose permease of Salmonella enterica serovar Typhimurium (Mel

221 The melibiose permease of Salmonella typhimurium (MelB(St)) catalyzes

222 The MelB permease of Salmonella typhimurium (MelB-ST) catalyzes t

223 d in TMAO metabolism, including Msil_3606, a permease of the amino acids-polyamine (APC) superfamily,

224 a putative transcription factor and a sugar permease of the phosphotransferase system (PTS), which a

225 apBC mutant, which lacks both inner membrane permeases of the Sap transporter, and tested the mutant

226 the LmGT4 permease (previously called the D2 permease), on a circular extrachromosomal element, and t

227 mutation in fucP (encoding a putative fucose permease), one of the genes in the plasticity region, we

228 The oligopeptide permease (opp) ABC transport system is a nutritional vir

229 gated the role of two conserved oligopeptide permeases, Opp and App, in the regulation of sporulation

230 s was the abundance of oligo- and di-peptide permeases (oppABCDF and dppABCDF) with each genome harbo

231 ispanning membrane proteins such as mannitol permease or TatC, which had been considered to be exclus

232 of the FCY2 gene, encoding a purine-cytosine permease, or the HPT1 gene, encoding the hypoxanthine gu

233 the ATP-binding cassette (PA14_57880) or the permease (PA14_57870) produced substantially less extrac

234 The 4-hydroxybenzoate permease PcaK was shown to modulate the chemotactic resp

235 own that the parasite plasma membrane purine permease, PfNT1, plays an essential function in the tran

236 Here, we describe an intracellular permease, PfNT2.

237 of sucrose permease (CscB) and phenylalanine permease (PheP) as a function of membrane lipid composit

238 ine transport system involving the polyamine permeases PotH and PotI, and was reversible.

239 s, extracellular solute binding proteins and permeases predicted to be active on milk oligosaccharide

240 an alternative hexose transporter, the LmGT4 permease (previously called the D2 permease), on a circu

241 for vaccine antigens identified oligopeptide permease protein A (OppA), an oligopeptide binding prote

242 e triple co-silencing of SlVRSLip, LeHT1 and Permease provoked an immediate cessation of growth of R

243 Additional copies of the pea amino acid permease PsAAP1 were introduced into the pea genome and

244 We found that the lactose permease purified from Escherichia coli cells exhibiting

245 Furthermore, the permeases PurP and YjcD were subjected to site-directed

246 grown in poor nitrogen medium, the nitrogen permease reactivator kinase (Npr1) inhibits TORC1 activi

247 shift mutation in the gene encoding nitrogen permease regulator-like 3 (NPRL3).

248 CPr14 shows decreased activity with most PTS permeases relative to HPr, but increases activity with t

249 Ammonium transporter/methylamine permease/rhesus (AMT/Mep/Rh) transporters are responsibl

250 iquitous ammonium transporter/methylammonium permease/rhesus protein (Amt/Mep/Rh) family of transport

251 erichia coli, DtpA (dipeptide and tripeptide permease), shows a high similarity to human PepT1 (SLC15

252 ort elicited endocytosis of other amino acid permeases similarly involves unmasking of a cytosolic Ar

253 libiose permease (MelB) is one among several permeases subject to IIA(Glc) regulation.

254 ability, as did deletion of the oligopeptide permease subunit oppD, suggesting that XIP is imported.

255 es diversion of the high affinity tryptophan permease Tat2 to the vacuole rather than the plasma memb

256 P-binding protein (TDE0143), a transmembrane permease (TDE0144), and a cytosolic ATPase (TDE0145).

257 ABC) transporter, with TGD1 representing the permease, TGD2 the substrate binding protein, and TGD3 t

258 We propose that ArsJ is an efflux permease that extrudes 1As3PGA from cells, where it rapi

259 he opp operon, which encodes an oligopeptide permease that is essential for sporulation and genetic c

260 The genes bbb22 and bbb23 encode purine permeases that are essential for B. burgdorferi mouse in

261 lated proteins are conserved, membrane-bound permeases that bind and translocate heme in metazoan cel

262 silicification includes a family of membrane permeases that recognize and actively transport the solu

263 ained mutant of the Escherichia coli lactose permease (the LacY double-Trp mutant Gly-46-->Trp/Gly-26

264 sylase activity or from defects in AmpG, the permease through which PG monomers enter the cytoplasm f

265 RNA-binding protein CsrA and the tryptophan permease TnaB coregulate tryptophanase activity, through

266 genes for trytophanase (tnaA), a tryptophan permease (tnaB), and a nitrate reductase (narG), as well

267 nutrients induce endocytosis of the cognate permeases to prevent toxic accumulation of metabolites.

268 HPr functions in concert with particular PTS permeases to prioritize carbohydrate utilization by modu

269 quires the coordinated actions of HRG-1 heme permeases to transport environmental heme into the intes

270 sine uptake by the wild-type and mutant Can1 permeases, together with docking calculations for each a

271 Moreover, the nascent full-length metal permease-transcriptional repressor protein was processed

272 s of the sterol sensing domain (SSD) and the permease transporter domain GxxxD/E motif reveal that th

273 (SBPs) for TRAP (tripartite ATP-independent permease) transporters for four-carbon acids, including

274 B, oppC, oppD, oppF, and oppA), encoding two permeases, two ATPases, and a substrate binding protein.

275 and a specific porin (OphP) in addition to a permease-type phthalate transporter (OphD).

276 Investigation of a purine permease-type sequence within a recently discovered opia

277 ransporter family expands the role of purine permease-type transporters in specialized metabolism, an

278 t of nodules requires the function of ureide permeases (UPS1) located in cells adjacent to the vascul

279 hia coli mutant lacking the bacterial uracil permease uraA allowed a detailed biochemical characteriz

280 hia coli has 10 members, of which the uracil permease UraA and the xanthine permeases XanQ and XanP a

281 on the recently described x-ray structure of permease UraA.

282 he substrate determining components of these permeases viz.

283 Disruption of ampG (peptidoglycan permease), waaL (lipopolysaccharide O antigen ligase), o

284 targeting of LmxGT1, and trafficking of the permease was arrested in the flagellar pocket.

285 mammalian macrophages, the function of this permease was examined under acidic pH conditions.

286 ion of SlVRSLip and LeHT1; expression of the Permease was not affected by silencing SlVRSLip or LeHT1

287 by ScoC and encodes a putative oligopeptide permease, was activated indirectly by CodY due to CodY-m

288 to known Saccharomyces cerevisiae polyamine permeases, we identified six C. albicans Dur polyamine t

289 e membrane, and V320N (TM10) inactivates the permease, whereas R327G (TM10) or S426N (TM14) reduces t

290 GAP1 encodes the general amino acid permease, which transports amino acids across the plasma

291 of protonated ammonium outward via the UreI permease, which was shown to facilitate diffusion of bot

292 By monitoring fluorescently labeled lactose permease with single-molecule sensitivity, we investigat

293 ransport dynamics is determined by glutamine permeases with two different kinds of kinetics.

294 family transporters and other Na(+)-coupled permeases within MFS has been lacking, although a wealth

295 t from our previous Cys-scanning analysis of permease XanQ, we subjected YgfU to rationally designed

296 ch the uracil permease UraA and the xanthine permeases XanQ and XanP are functionally known.

297 ure experiments, a xanthine/uracil/vitamin C permease (XUV) was upregulated approximately 20-fold und

298 lved crystallographic models of the D-xylose permease XylE from Escherichia coli and GlcP from Staphy

299 a coli identified the so far uncharacterized permease YbeC as the major serine transporter of B. subt

300 utants in the yclNOPQ transporter, including permease YclN, ATPase YclP, and a substrate-binding prot