ライフサイエンスコーパス: peroxisomal

1 ion using GFP fusion suggested that Aa547 is peroxisomal.

2 One pfl mutant was missing the peroxisomal 3-ketoacyl-CoA thiolase encoded by the PEROX

3 -DEPENDENT1 (SDP1) triacylglycerol lipase or PEROXISOMAL ABC TRANSPORTER 1 (PXA1), here we show that

4 the D-bifunctional protein (HSD17B4) and the peroxisomal ABC transporter ABCD3 are essential in perox

5 The peroxisomal ABC transporter, Comatose (CTS), a full leng

6 tification of mRNA and protein levels of the peroxisomal ABC transporters and by blocking with specif

7 hat CGI-58 functions by interacting with the PEROXISOMAL ABC-TRANSPORTER1 (PXA1), a protein that tran

8 Evidence is shown that the peroxisomal ABCD transporter (PXA1) plays a critical rol

9 However, oligomerization of peroxisomal ABCD transporters is incompletely understood

10 t, M1 Spastin forms a tethering complex with peroxisomal ABCD1 to promote LD-peroxisome contact forma

11 a-ketoacyl-(acyl-carrier-protein) synthases, peroxisomal acyl-activating enzymes, ATP binding cassett

12 gain- and loss-of-function mutations in the peroxisomal acyl-CoA oxidase 1 (ACOX1) gene cause neurod

13 An Arabidopsis mutant defective in two peroxisomal acyl-CoA oxidases does not metabolize ascr#1

14 palmitic acid, leading to the production of peroxisomal acylcarnitine intermediates.

15 PH1 is caused by a deficiency of liver-peroxisomal alanine: glyoxylate aminotransferase (AGT),

16 ts demonstrate that this FAR-like protein is peroxisomal and bifunctional, providing both substrates

17 domain containing protein 5 (ACBD5), is also peroxisomal and is required specifically for pexophagy.

18 ting technology to simultaneously manipulate peroxisomal and mitochondrial fatty acid beta-oxidation

19 0, which promotes steatosis by dysregulating peroxisomal and mitochondrial lipid homeostasis.

20 salivary gland and muscle strikingly altered peroxisomal and mitochondrial morphology.

21 studies showed that Lcn2 deficiency impairs peroxisomal and mitochondrial oxidation of lipids and at

22 death, and indicated impaired mitochondrial, peroxisomal, and liver functions.

23 xylate, riboflavin, branch chain amino acid, peroxisomal, and mitochondrial metabolism.

24 ABCD1 and its homolog ABCD2 are peroxisomal ATP-binding cassette (ABC) half-transporters

25 by mutations in the ABCD1 gene encoding the peroxisomal ATP-binding cassette (ABC) transporter ABCD1

26 In this report, we demonstrate that the peroxisomal ATP-binding cassette transporter COMATOSE is

27 novel tool to study substrate specificity of peroxisomal ATP-binding cassette transporters.

28 s may reflect unanticipated functions of the peroxisomal ATPase complex.

29 Accumulation of transcripts encoding peroxisomal-based beta-oxidation did not change in respo

30 -oxidation; this is in stark contrast to the peroxisomal-based pathways observed in plants and green

31 ng the involvement of their gene products in peroxisomal beta-oxidation and initial seedling growth.

32 B'theta knockout mutants were impaired in peroxisomal beta-oxidation as shown by developmental arr

33 Peroxisomal beta-oxidation cycles are required for the b

34 Peroxisomal beta-oxidation cycles shorten the side chain

35 llweger syndrome patients to investigate the peroxisomal beta-oxidation defect.

36 Adipose-specific knockout of the peroxisomal beta-oxidation enzyme acyl-CoA oxidase 1 (Ac

37 Peroxisomal beta-oxidation has recently been shown to co

38 entry of fatty acyl coenzyme As (CoAs) into peroxisomal beta-oxidation in the intestine blunts the e

39 ent of ca. 200 components from wild-type and peroxisomal beta-oxidation mutants including (omega - 1)

40 Peroxisomal beta-oxidation of C26:0 was normal, but beta

41 e for protein myristoylation and a potential peroxisomal beta-oxidation product.

42 cs revealed that interfering with intestinal peroxisomal beta-oxidation results in a modest global tr

43 hat plants, like nematodes, employ conserved peroxisomal beta-oxidation to edit ascarosides and chang

44 t TAG-derived fatty acids are metabolized by peroxisomal beta-oxidation to produce ATP required for s

45 tion of fatty acids from membrane lipids for peroxisomal beta-oxidation under prolonged dark treatmen

46 tion synergistically in directing FAs toward peroxisomal beta-oxidation via TAG intermediates, thereb

47 s and proteins involved in mitochondrial and peroxisomal beta-oxidation, have an increased rate of fa

48 the enzyme that catalyzes the first step in peroxisomal beta-oxidation, is enriched in liver and fur

49 ong-chain fatty acids and partially impaired peroxisomal beta-oxidation.

50 s exhibited a significant down-regulation of peroxisomal biogenesis and metabolism (e.g., PEX13p and

51 Inherited peroxisomal biogenesis disorders (PBDs) are characterize

52 or PEX5, whose deficiency causes fatal human peroxisomal biogenesis disorders (PBDs).

53 Peroxisomal biogenesis factor 11 (PEX11) proteins are fo

54 g of newly synthesized proteins by cytosolic peroxisomal biogenesis factor 5 (PEX5) followed by inser

55 Adipose-specific knockout of the peroxisomal biogenesis factor Pex16 (Pex16-AKO) in mice

56 Mechanistic studies revealed a decrease in peroxisomal biogenesis factor-2 and fewer peroxisomes in

57 They are caused by mutations of peroxisomal biogenesis factors encoded by Pex genes, and

58 Adipose tissue peroxisomal biogenesis was induced in response to cold e

59 hway, as Sirt5KO mice exhibited no change in peroxisomal C(12) beta-oxidation.

60 isease and showed a striking accumulation of peroxisomal C27-bile acid intermediates in plasma.

61 evelop a sensitive high-throughput assay for peroxisomal cargo import.

62 of catalase A (Cta1), the mitochondrial and peroxisomal catalase isoform in yeast.

63 s (Arabidopsis thaliana) mutants lacking the peroxisomal CATALASE2 (cat2-2) that display stunted grow

64 and this is discussed in the context of the peroxisomal coenzyme A (CoA) budget.

65 To form a new peroxisomal compartment, ER-derived preperoxisomal vesic

66 amine oxidase serves the same purpose as the peroxisomal compartmentalization of oxidases in eukaryot

67 s mature, metabolic requirements change, and peroxisomal contents are remodeled.

68 ECH2 was suggested to function in the peroxisomal conversion of indole-3-butyric acid (IBA) to

69 In renal tubules, preconditioning prevented peroxisomal damage and abolished oxidative stress and in

70 The peroxisomal defect explains the developmental phenotypes

71 ucts (like bile acids or plasmalogens), many peroxisomal defects lead to detrimental mitochondrial ab

72 Peroxisomal defects were exacerbated in RING peroxin dou

73 to-Lys missense allele that conferred severe peroxisomal defects, including impaired beta-oxidation,

74 roxisome biogenesis gene PEX13 with striking peroxisomal defects.

75 ytological, and biochemical assays to reveal peroxisomal deficiencies.

76 induces their fragmentation and inhibits the peroxisomal-dependent antiviral signalling pathway.

77 mutations in these proteins frequently cause peroxisomal diseases.

78 d adrenoleukodystrophy (X-ALD), an inherited peroxisomal disorder, is caused by mutations in the ABCD

79 s fatty acid accumulates in people with some peroxisomal disorders and is traditionally related to ne

80 mmary gland development as a new category of peroxisomal disorders.

81 -like GTPase that mediates mitochondrial and peroxisomal division in a process dependent on self-asse

82 racterization of the major components of the peroxisomal docking complex Pex14p/Pex17p, in a native b

83 the cytosol, the receptor interacts with the peroxisomal docking/translocation machinery, where it ge

84 s with sensorineural hearing loss, regulates peroxisomal dynamics and the antioxidant defense trigger

85 um produces time course-dependent changes in peroxisomal dynamics, starting with peroxule formation,

86 Peroxisomal dynamics, such as the proliferation, movemen

87 Thus, peroxisomal dysfunction causes secondary failure of loca

88 orphic allele that results in extremely mild peroxisomal dysfunction.

89 Here, we report that the peroxisomal E3 ubiquitin ligase peroxin 2 (PEX2) is the

90 pexophagy by counteracting the action of the peroxisomal E3 ubiquitin ligase PEX2.

91 Besides accumulation of peroxisomal educts (like very-long-chain fatty acids [VL

92 Our findings establish peroxisomal engineering as an efficient strategy for the

93 ey stone disease caused by deficiency of the peroxisomal enzyme alanine: glyoxylate aminotransferase

94 The gene encoding the liver-specific peroxisomal enzyme alanine:glyoxylate aminotransferase (

95 ) encodes branched-chain acyl-CoA oxidase, a peroxisomal enzyme believed to be involved in the metabo

96 Interestingly, upon CHP1 loss, the peroxisomal enzyme, GNPAT, partially compensates for the

97 Import of peroxisomal enzymes is facilitated by peroxins including

98 The importance of peroxisomal FA beta-oxidation in algal physiology was sh

99 We summarize that peroxisomal FAO is important when mitochondrial FAO is d

100 vokes mitochondrial biogenesis, compensatory peroxisomal fat oxidation, and amino acid catabolism.

101 ich is responsible for the first step of the peroxisomal fatty acid (FA) beta-oxidation spiral.

102 Degradation of these substrates requires peroxisomal fatty acid beta-oxidation plus additional en

103 This coincided with higher peroxisomal fatty acid oxidation compared with mitochond

104 egulates the balance of mitochondrial versus peroxisomal fatty acid oxidation in proximal tubular epi

105 Peroxisomal fatty acyl-CoA reductase 1 (Far1) is essenti

106 DRP1) critically regulates mitochondrial and peroxisomal fission in multicellular organisms.

107 The initial phase of peroxisomal fission requires the peroxisomal membrane pr

108 ing Golgi apparatus to endosome and vacuole, peroxisomal fission, and endocytic scission.

109 nt with a lethal defect of mitochondrial and peroxisomal fission.

110 that inhibiting this interaction compromises peroxisomal fission.

111 so plays a crucial role in the final step of peroxisomal fission: dynamin-like protein (DLP)-mediated

112 In vitro import of proteins into isolated peroxisomal fractions has provided a wealth of knowledge

113 Importantly, we demonstrate that peroxisomal fragmentation is not essential for vMIA to s

114 The loss of peroxisomal function has been implicated in many neurode

115 forms the basis of a system in which normal peroxisomal function is downregulated and replaced with

116 To comprehensively investigate the impact of peroxisomal function on photosynthesis, especially under

117 e, the molecular mechanisms by which reduced peroxisomal functions contribute to enhanced fibrosis we

118 peroxisomal mutants involved in PR and other peroxisomal functions in the photometric screen will ena

119 sturbing peroxisome function by knockdown of peroxisomal gene Pex14 or Mfp2 markedly increased the LP

120 ll types, knockout of lipid biosynthetic and peroxisomal genes causes fitness defects only in low oxy

121 rs or GO inhibitors may restore the abnormal peroxisomal glyoxylate pathway in PH1 patients.

122 notransferase (AGT) are both involved in the peroxisomal glyoxylate pathway.

123 oteins that are required for protein import, peroxisomal growth, and division.

124 we focused on the photorespiration-dependent peroxisomal H2O2 production in Arabidopsis thaliana muta

125 s the cellular redox homeostasis by limiting peroxisomal H2O2 production.

126 We investigated mutant lines lacking peroxisomal hydroxypyruvate reductase to determine if th

127 2 fusions with a free C terminus resulted in peroxisomal import after dimerization, and PGD2 could be

128 minally truncated PGD2-1 protein showed that peroxisomal import and catalytic activity are abolished.

129 t induction of upd3 is triggered by impaired peroxisomal import and elevated JNK signaling in aged oe

130 ack peroxisomal targeting signals, and their peroxisomal import depends on B'theta and appears to occ

131 ify an important role of hepatocyte-specific peroxisomal import in mediating non-autonomous regulatio

132 ow the following: (i) Pex21p is required for peroxisomal import of Gpd1p as well as a key enzyme of t

133 n investigated by docking human MCD onto the peroxisomal import protein peroxin 5, which revealed int

134 For example, the TPR domains in the peroxisomal import receptor PEX5 enable binding to a ran

135 yte-specific overexpression of Pex5, the key peroxisomal import receptor, blocks age-related upd3 ind

136 vely kill Trypanosoma by blocking glycosomal/peroxisomal import that depends on the PEX14-PEX5 protei

137 ding and is a prerequisite for PTS2-mediated peroxisomal import.

138 nsporters predicted to homodimerize and form peroxisomal importers for fatty acyl-CoAs.

139 lates segregation, packaging, and budding of peroxisomal importomer subcomplexes, thereby preventing

140 nique should be applied to future studies of peroxisomal in vitro import.

141 Peroxisomal LDH is conserved in mammals and likely contr

142 raction reflects its direct contact with the peroxisomal lipid bilayer.

143 Here, we describe a role for peroxisomal lipid metabolism in mitochondrial dynamics i

144 munofluorescence studies revealed a specific peroxisomal localization for Eci3.

145 T1 without the transit peptide (enforcing ER/peroxisomal localization) increased gpt1 transmission si

146 ed by confocal microscopy analysis suggested peroxisomal localization.

147 uorescent protein-tagging study pointed to a peroxisomal location of CrACX2.

148 eraction between the ABC transporter and the peroxisomal long chain acyl-CoA synthetases (LACS)6 and

149 ABCD2 (D2) is a peroxisomal long-chain acyl-CoA transporter that is high

150 truncated PEX5 (PEX5C) receptor construct or peroxisomal malate dehydrogenase 1 (pMDH1) cargo protein

151 Most proteins destined for the peroxisomal matrix depend on the peroxisomal targeting s

152 The peroxisomal matrix protein import is facilitated by cycl

153 ubiquitylation stabilizes PEX5 and promotes peroxisomal matrix protein import, suggesting that mulib

154 lier views that Pex1 and Pex6 play a role in peroxisomal matrix protein import.

155 brane remnants (ghosts) rapidly incorporated peroxisomal matrix proteins and developed into peroxisom

156 Peroxisomal matrix proteins are synthesized on cytosolic

157 hemistry revealed that these structures lack peroxisomal matrix proteins but are the sole sites of th

158 Peroxisomal matrix proteins carry peroxisomal targeting

159 Peroxisomal matrix proteins carry peroxisome-targeting s

160 The destination of peroxisomal matrix proteins is encoded by short peptide

161 Import of yeast peroxisomal matrix proteins is initiated by cytosolic re

162 able property of the machinery for import of peroxisomal matrix proteins is that it can accept alread

163 Most peroxisomal matrix proteins possess a C-terminal targeti

164 Import of peroxisomal matrix proteins, crucial for peroxisome biog

165 g signals (PTS1/PTS2) identified 51 putative peroxisomal matrix proteins.

166 embrane integrity and the release of soluble peroxisomal matrix proteins.

167 ivers cargo proteins from the cytosol to the peroxisomal matrix.

168 y which it is able to specifically evade the peroxisomal MAVS-dependent antiviral signalling.

169 ecifically inhibit signalling downstream the peroxisomal MAVS.

170 IA is able to specifically interact with the peroxisomal MAVS.

171 o interact with both the plasma membrane and peroxisomal membrane and has the structural and function

172 : direct insertion from the cytosol into the peroxisomal membrane and indirect trafficking to peroxis

173 binding domain, forming a bridge between the peroxisomal membrane and the plasma membrane.

174 insertion of the PEX5-cargo complex into the peroxisomal membrane at the docking/translocation module

175 g cassette (ABC) transporters present in the peroxisomal membrane catalyzing ATP-dependent transport

176 To understand the functional role of the peroxisomal membrane channel Pxmp2, mice with a targeted

177 anelle, these receptors are removed from the peroxisomal membrane or matrix.

178 , carnitine palmitoyl transferase I (CPT1)a, peroxisomal membrane protein 70 (PMP70) (modest down-reg

179 ns A and B (VAPA and VAPB) interact with the peroxisomal membrane protein acyl-CoA binding domain con

180 al phase of peroxisomal fission requires the peroxisomal membrane protein Peroxin 11 (Pex11p), which

181 For example, co-regulation of the peroxisomal membrane protein PEX11beta with mitochondria

182 we defined the binding site for Atg30 on the peroxisomal membrane protein Pex3 and uncovered a role f

183 astly, we show that Pex15 interacts with the peroxisomal membrane protein Pex3, which shields Pex15 f

184 , which is recruited to the organelle by the peroxisomal membrane protein Pex3.

185 -binding protein, Atg37, that is an integral peroxisomal membrane protein required specifically for p

186 Peroxisomal membrane proteins (PMPs) traffic to peroxiso

187 ses and also peroxins that mediate import of peroxisomal membrane proteins from the ER, hinting at du

188 Other peroxisomal membrane proteins in these cells are unstabl

189 proteins but are the sole sites of the major peroxisomal membrane proteins Pex2, Pex10, Pex11, Pex13,

190 In mammalian cells, ubiquitination of peroxisomal membrane proteins signals pexophagy; however

191 However, the sorting mechanisms segregating peroxisomal membrane proteins to the preperoxisomal endo

192 rus has developed a strategy to highjack the peroxisomal membrane proteins' transport machinery.

193 derived vesicles containing distinct sets of peroxisomal membrane proteins.

194 ction of Pex1 in Pex1-deficient cells, these peroxisomal membrane remnants (ghosts) rapidly incorpora

195 We observed that the cells contained peroxisomal membrane remnants, which in ultrathin cross

196 rane enclosing a protein lumen, more complex peroxisomal membrane structure has occasionally been obs

197 in Pex3 is not required for the formation of peroxisomal membrane structures in yeast pex3 mutant cel

198 nspecific metabolite permeability across the peroxisomal membrane using a polymer exclusion assay.

199 of vesicle (spherule)-like structures in the peroxisomal membrane with tight openings toward the cyto

200 the PEX5 receptor docking with PEX13 at the peroxisomal membrane, and we found severely reduced impo

201 At the peroxisomal membrane, the cargo-loaded receptor interact

202 protein removes ubiquitinated PEX5 from the peroxisomal membrane.

203 g ABCD2 exist mainly as homotetramers in the peroxisomal membrane.

204 cture of the ABCD1 and ABCD2 proteins in the peroxisomal membrane.

205 ors that shuttle between the cytosol and the peroxisomal membrane.

206 facilitates PEX5 retrotranslocation from the peroxisomal membrane.

207 de ubiquitin-protein ligases anchored in the peroxisomal membrane.

208 rmation, and appear to derive from the outer peroxisomal membrane.

209 roxisomal targeting signal 1 receptor at the peroxisomal membrane.

210 and directs them to a docking complex at the peroxisomal membrane.

211 We found that TRIM37 localizes in peroxisomal membranes and ubiquitylates PEX5 at K464 by

212 sis thaliana lon2 mutants display defects in peroxisomal metabolism and matrix protein import but app

213 TIVE1 (PED1/At2g33150) gene, suggesting that peroxisomal metabolism influences the rate of matrix pro

214 ch individual gene involved in the cytosolic/peroxisomal mevalonate and plastidial methylerythritol p

215 The identification of peroxisomal mutants involved in PR and other peroxisomal

216 rabidopsis (Arabidopsis thaliana) called the peroxisomal NAD carrier (PXN).

217 When cells are grown on oleate medium, peroxisomal NADH is reoxidised to NAD(+) by malate dehyd

218 DHAR3 is chloroplastic, with no evidence for peroxisomal or mitochondrial localizations.

219 n of lipid rafts, but was independent of the peroxisomal or transcriptional activities of scp2.

220 itochondria, plasma membrane NADPH oxidases, peroxisomal oxidases, type III peroxidases and other apo

221 We did not find evidence of peroxisomal oxidation of glutarate.

222 ockout (KO) uncovered a significant residual peroxisomal oxidation of lauric and palmitic acid, leadi

223 somal ABC transporter ABCD3 are essential in peroxisomal oxidation of lauric and palmitic acid.

224 Investigation of peroxisomal parameters in skin fibroblasts revealed a re

225 We found that a small fraction of peroxisomal Pex15, exaggerated by overexpression, is tur

226 These analyses showed that peroxisomal PGD2 activity is required for guided growth

227 0-2 Arabidopsis mutants exhibited defects in peroxisomal physiology and matrix protein import.

228 n in genes related to neurodevelopmental and peroxisomal processes that play a key role in the matura

229 ing those of photorespiration (PR) and other peroxisomal processes, some of which may also be related

230 Furthermore, peroxisomal production improves subsequent decoration by

231 we examined the effects of the commonly used peroxisomal proliferated activated receptor alpha agonis

232 Proteome disturbances reflected peroxisomal proliferation, steatosis and necrosis.

233 models for GSD Ia were treated with the pan-peroxisomal proliferator-activated receptor agonist, bez

234 metabolomic analyses revealed marked loss of peroxisomal proliferator-activated receptor-alpha (PPARa

235 abolic profiling including (a) activation of peroxisomal proliferator-activated receptor-alpha and it

236 , PGC1alpha, and (b) increased expression of peroxisomal proliferator-activated receptor-gamma and ge

237 rmerly 2B), catalytic subunit, beta isoform; peroxisomal proliferator-activated receptor-gamma-DBD-in

238 sis that the Pex1/Pex6 complex has a role in peroxisomal protein import analogous to p97 in ER-associ

239 this approach to the control of nuclear and peroxisomal protein import and the generation of biotin-

240 Proteins designated for peroxisomal protein import harbor one of two common pero

241 Labeling of the peroxisomal protein import machinery by PEX5C demonstrat

242 rotein-protein interactions that control the peroxisomal protein import pathway can be manipulated to

243 Here the authors engineer a peroxisomal protein import pathway orthogonal to the nat

244 Membrane-associated events during peroxisomal protein import processes play an essential r

245 experimental tool to give new insights into peroxisomal protein import, the variant receptor-signal

246 roxisomally metabolized auxin precursor, and peroxisomal protein import.

247 in and examined how the localization of each peroxisomal protein is affected.

248 Catalase, traditionally considered a peroxisomal protein, was found to be present in cardiac

249 ittle is known about how damaged or obsolete peroxisomal proteins are degraded.

250 Recently, several dozens of novel peroxisomal proteins have been identified from Arabidops

251 orescence microscopy validated around 10 new peroxisomal proteins in Arabidopsis.

252 mp2 led to an elevation in the expression of peroxisomal proteins in the mammary fat pad but not in l

253 he heterogeneous spatial organization of the peroxisomal proteins PEX5, PEX14, and PEX11 around activ

254 er 150 Arabidopsis mutants of genes encoding peroxisomal proteins was conducted using the automated D

255 al methods is essential for determination of peroxisomal proteomes in silico but has proved challengi

256 r structures that harbor key proteins of the peroxisomal receptor docking complex-Pex13 and Pex14-as

257 We propose that the presence of multiple peroxisomal redox shuttles allows eukaryotic cells to ma

258 tles allows eukaryotic cells to maintain the peroxisomal redox status under different metabolic condi

259 both isoforms comprised a C-terminal type 1 peroxisomal retention motif, and HMGL51 contained a mito

260 6 and pex26 seedlings, suggesting a role for peroxisomal retrotranslocation machinery in oil body uti

261 nally targeted to the organelle by PEX5, the peroxisomal shuttling receptor.

262 ducing equivalents from mitochondria for the peroxisomal steps of photorespiration versus oxidation o

263 Peroxisomal sulfite oxidase transcripts and activity lev

264 ff, MiD49 and MiD51 were not targeted to the peroxisomal surface, suggesting that they specifically a

265 d tail-anchored (TA) proteins, including the peroxisomal TA protein Pex15.

266 Here, Far1 is shown to be a peroxisomal tail-anchored protein.

267 or plastidic enzyme plus whether PGD2 with a peroxisomal targeting motif also might target plastids.

268 re we report the use of a fluorescein-tagged peroxisomal targeting sequence peptide (F-PTS1, acetyl-C

269 AGT contains a C-terminal peroxisomal targeting sequence, but mutations generate a

270 lly import proteins via one of two conserved peroxisomal targeting signal (PTS1 or 2) mediated pathwa

271 eptor Pex5, which recognizes proteins with a peroxisomal targeting signal 1 (PTS1) in the cytosol and

272 in Pex5 are important for processing of the peroxisomal targeting signal 1 receptor at the peroxisom

273 tor PEX5 enable binding to a range of type 1 peroxisomal targeting signal motifs.

274 mediates the import of proteins harboring a peroxisomal targeting signal of type I (PTS1).

275 By tagging TaFAR enzyme with peroxisomal targeting signal peptides, the TaFAR could b

276 to HCN channels and limits binding to type 1 peroxisomal targeting signal substrates.

277 We identify an enhanced peroxisomal targeting signal type 1 (PTS1) for rapidly s

278 xtensions in silico with a new predictor for peroxisomal targeting signal type 1 (PTS1).

279 % identity homologous to Eci2 and contains a peroxisomal targeting signal type 1.

280 sequences, which have been characterized as peroxisomal targeting signals (PTS) residing either at t

281 omal protein import harbor one of two common peroxisomal targeting signals (PTS).

282 ysis of cellular fractions and prediction of peroxisomal targeting signals (PTS1/PTS2) identified 51

283 Peroxisomal matrix proteins carry peroxisomal targeting signals (PTSs), PTS1 or PTS2, and

284 ned for the peroxisomal matrix depend on the peroxisomal targeting signals (PTSs), which require the

285 X5 and PEX7 that recognize proteins carrying peroxisomal targeting signals 1 or 2 (PTS1 or PTS2), res

286 C and A subunits lack peroxisomal targeting signals, and their peroxisomal imp

287 mitochondria, uses a similar strategy to the peroxisomal TBSV to hijack the Rab5-positive endosomes i

288 the mitochondrial CIRV, but not against the peroxisomal tombusviruses in yeast and plants.

289 ochondrial CIRV, but not against the related peroxisomal tombusviruses.

290 linium chloride (DECA), could restore proper peroxisomal trafficking of AGT(P11LG170R).

291 n B1, BPI fold-containing family B member 1, peroxisomal trans-2-enoyl-coenzyme A reductase, phosphol

292 Consistently, we find that the peroxisomal transfer of PEX7 depends on cargo binding an

293 ations of Pex14p/Pex17p for formation of the peroxisomal translocon are discussed.

294 proteins fuse, allowing the assembly of the peroxisomal translocon.

295 ABCD1 encodes a peroxisomal transmembrane protein required for very long

296 We previously identified a peroxisomal transport protein in Arabidopsis (Arabidopsi

297 unction is completely dependent on the ABCD3 peroxisomal transporter.

298 ion of SUGAR-DEPENDENT1 (SDP1) TAG lipase or PEROXISOMAL TRANSPORTER1 (PXA1) severely decreases FA tu

299 tween lipid storage, lipid mobilization, and peroxisomal utilization of fatty acids as a carbon sourc

300 Information on the peroxisomal versus mitochondrial catabolism was gathered