ライフサイエンスコーパス: peroxisome

1 ane protein proposed to regulate Msp1 at the peroxisome.

2 y acid oxidation, which was localized to the peroxisome.

3 t GPT1 is indispensable in both plastids and peroxisomes.

4 es cerevisiae revealed specific targeting to peroxisomes.

5 other organelles physically interacting with peroxisomes.

6 domains mark contact sites with lysosomes or peroxisomes.

7 to the endoplasmic reticulum (ER) and around peroxisomes.

8 localized to punctate structures resembling peroxisomes.

9 nsfer lipids to various organelles including peroxisomes.

10 ated with defective FA metabolism in LDs and peroxisomes.

11 , the outer mitochondrial membrane (OMM) and peroxisomes.

12 abolites, and biogenesis of mitochondria and peroxisomes.

13 s a venue to reveal the uncharted biology of peroxisomes.

14 agy, the selective autophagic degradation of peroxisomes.

15 r NAD(+)-dependent reaction performed inside peroxisomes.

16 her GPT1 may dually localize to plastids and peroxisomes.

17 ic reticulum, chloroplasts, mitochondria and peroxisomes.

18 earson correlation coefficient for yield and peroxisome abundance (r = -0.59) was higher than for com

19 Our work established peroxisome abundance as a cellular sensor for measuring

20 incipal component analysis demonstrated that peroxisome abundance correlated positively with H(2) O(2

21 Here we determined the correlation of peroxisome abundance with physiological responses and yi

22 During virus infections in humans, peroxisomes act as important immune signaling organelles

23 expression of the transcriptional regulator peroxisome activator receptor-gamma (PPAR-gamma).

24 udies have added greatly to our knowledge of peroxisomes, addressing areas such as the diverse proteo

25 ors in the ER required for the biogenesis of peroxisomes also impact the formation of lipid droplets.

26 tion indicates that allantoin is produced in peroxisomes and degraded in the endoplasmic reticulum (E

27 M1 Spastin's dual roles in tethering LDs to peroxisomes and in recruiting ESCRT-III components to LD

28 fatty acid (VLCFA) beta-oxidation pathway in peroxisomes and leads to H(2)O(2) production.

29 The dynamic interface between peroxisomes and lipid droplets, and also between these o

30 s to discover an organelle interface between peroxisomes and mitochondria in mammalian cells.

31 ngs support a surprising interaction between peroxisomes and mitochondria regulating mitochondrial dy

32 any of which are carried out coordinately by peroxisomes and other organelles physically interacting

33 l CTS mutants were expressed and targeted to peroxisomes and retained substrate-stimulated ATPase act

34 al repair following injury, which depends on peroxisomes and their action inducing JAK/Stat signaling

35 To more fully understand the roles of peroxisomes and to take advantage of their many properti

36 us and at the plasma membrane, mitochondria, peroxisomes, and other cytoplasmic vesicular structures.

37 the cytosolic leaflets of the Golgi complex, peroxisomes, and outer mitochondrial membrane, but only

38 In plants, peroxisomes are essential for growth and development and

39 Peroxisomes are essential organelles for the specialized

40 ose and reframe models for understanding how peroxisomes are formed in cells.

41 Peroxisomes are highly dynamic, changing in abundance in

42 Peroxisomes are multifunctional organelles with roles in

43 Peroxisomes are small, ubiquitous organelles that are de

44 The biogenesis and function of peroxisomes are tightly coupled with mitochondria.

45 Peroxisomes are vital organelles that compartmentalize c

46 nd used the Pex5-mediated targeting to yeast peroxisomes as a model.

47 screens to identify the oxidative organelles peroxisomes as critical contributors to ferroptosis sens

48 This revision of the classical view of peroxisomes as single-membrane organelles has implicatio

49 roxisome proliferation involving pejvakin, a peroxisome-associated protein from the gasdermin family,

50 ion of the PM-PER tether and show it anchors peroxisomes at the mother cell cortex, suggesting a new

51 Excess H(2) O(2) triggers chloroplast and peroxisome autophagy and programmed cell death.

52 tive phosphorylation, fatty acid metabolism, peroxisome, bile acid metabolism, xenobiotic metabolism,

53 This review highlights the links between peroxisome biogenesis and degradation, incorporating an

54 ganelles has implications for all aspects of peroxisome biogenesis and function and may help address

55 anding of players and mechanisms involved in peroxisome biogenesis and peroxisome degradation, very f

56 plications, we recast mechanisms controlling peroxisome biogenesis in a framework that integrates inf

57 Here, we review our understanding of peroxisome biogenesis to propose and reframe models for

58 ontology categories: fatty acid degradation, peroxisome biogenesis, fatty acid synthesis, and retinol

59 induce the neomorphic association of ER and peroxisomes by directly tethering the cytosolic domain o

60 owever, more recently it was discovered that peroxisomes can also benefit the virus, facilitating vir

61 Peroxisomes can oxidize medium- and long-chain fatty aci

62 complex with peroxisomal ABCD1 to promote LD-peroxisome contact formation.

63 and in recruiting ESCRT-III components to LD-peroxisome contact sites for FA trafficking may underlie

64 Using lipidomic profiling we show that peroxisomes contribute to ferroptosis by synthesizing po

65 Hsd17b4 KO mouse model, we demonstrated that peroxisomes contribute to the plasma acylcarnitine profi

66 , improved NADP-dependent HPR1 activities in peroxisomes could not compensate for the reduced NADH-de

67 anisms involved in peroxisome biogenesis and peroxisome degradation, very few studies have focused on

68 These results identify peroxisome-derived acetyl-CoA as a key metabolic regulat

69 ic motors are able to work in teams to drive peroxisome dispersion in cells.

70 hat uncovered this double-edged character of peroxisomes during infection, highlighting mechanisms th

71 However, the role of pejvakin in peroxisome dynamics and homeostasis remains unclear.

72 We term hormonal factors induced by peroxisome dysfunction as peroxikines.

73 Together, our work reveals roles for the peroxisome-ether-phospholipid axis in driving susceptibi

74 nd may help address fundamental questions in peroxisome evolution.

75 Furthermore, LD-to-peroxisome FA trafficking mediated by M1 Spastin is requ

76 o LDs via its MIT domain to facilitate LD-to-peroxisome FA trafficking, possibly through IST1- and CH

77 ummarizes our current understanding of plant peroxisomes, focusing on recent discoveries.

78 ery long chain fatty acids (VLCFAs) into the peroxisome for degradation.

79 FAs), but to harvest them, LDs donate FAs to peroxisomes for oxidation.

80 Plant peroxisomes function collaboratively with other subcellu

81 lastids and ACETATE NON-UTILIZING1 (ACN1) in peroxisomes, function redundantly to prevent the accumul

82 e Golgi complex > lysosomes > mitochondria ~ peroxisomes > endoplasmic reticulum, in decreasing order

83 Arabidopsis peroxisomes to demonstrate that peroxisomes have extensive internal membranes.

84 , these two opposing processes that regulate peroxisome homeostasis.

85 Peroxisomes import their luminal proteins from the cytos

86 turn attention to the reductive evolution of peroxisomes in anaerobic organisms.

87 The loss of peroxisomes in eukaryotes with reduced mitochondria is t

88 in peroxisomal biogenesis factor-2 and fewer peroxisomes in OL processes.

89 tudies by comparing the established roles of peroxisomes in plant infections and discussing the promi

90 Surprisingly, we identified peroxisomes in the anaerobic, hydrogenosome-bearing prot

91 e-associated protein 1 light chain 3beta) to peroxisomes in wild-type, but not Pjvk (-/-), mice.

92 Retention of peroxisomes in yeast mother cells requires Inp1, which i

93 d by this concept, herein we transform yeast peroxisomes into microfactories for geranyl diphosphate-

94 Because OPPP activity in peroxisomes is essential for fertilization, and immunobl

95 A subset of peroxisomes is retained at the mother cell cortex by the

96 ctopic placement of NDP52 on mitochondria or peroxisomes is sufficient to initiate selective autophag

97 atty acid beta-oxidation, a core function of peroxisomes, is impaired.

98 de novo biosynthesis of fatty acids and Leu; peroxisome-localized ACN1 enables the incorporation of a

99 Finally, we show that USP30 can rescue the peroxisome loss observed in some disease-causing peroxis

100 of Golgi elements (high-load cargo) but not peroxisomes (low-load cargo).

101 Here, we describe a peroxisome-lysosome metabolic link that restricts autoph

102 Plant peroxisomes maintain a plethora of key life processes in

103 role of the deubiquitinating enzyme USP30 in peroxisome maintenance.

104 xisome loss observed in some disease-causing peroxisome mutations, pointing to a potential therapeuti

105 In conclusion, we identified a subclass of peroxisomes, named "anaerobic" peroxisomes that shift th

106 Our results indicate that peroxisomes not only accept acyl-CoAs but can also oxidi

107 , P100-mediated HMGL inactivation outside of peroxisomes or mitochondria is crucial, protecting again

108 regime relevant to the hitchhiking motion of peroxisome organelles in fungal hyphae.

109 This fatty acid breakdown occurs in peroxisomes, organelles that sequester oxidative reactio

110 Peroxisomes perform essential functions in lipid metabol

111 nd rapid selective autophagic degradation of peroxisomes (pexophagy) in auditory hair cells from wild

112 e recycling of mitochondria (mitophagy), and peroxisomes (pexophagy).

113 In peroxisomes, photorespiratory HYDROXYPYRUVATE REDUCTASE1

114 Peroxisome-plasma membrane contact sites disappear upon

115 viruses have coevolved to take advantage of peroxisome plasticity.

116 Peroxisomes play a central role in human health and have

117 Although peroxisomes play a key role in plant metabolism under bo

118 tify Inp1 as the first known plasma membrane-peroxisome (PM-PER) tether by demonstrating that Inp1 me

119 pexophagy plays a key role in noise-induced peroxisome proliferation and identify defective pexophag

120 r dissecting the impact of abiotic stress on peroxisome proliferation because it is adapted to margin

121 Adaptive peroxisome proliferation involving pejvakin, a peroxisom

122 ive stress, and resulted in normal levels of peroxisome proliferation, whereas Pjvk cDNA alone yielde

123 LPS did not increase peroxisome proliferation-activated receptor gamma expres

124 1) in aged Paneth cells inhibits activity of peroxisome proliferator activated receptor alpha (PPAR-a

125 Peroxisome proliferator activated receptor beta/delta (P

126 TZDs) target the transcriptional activity of peroxisome proliferator activated receptor gamma (PPARga

127 Peroxisome proliferator activated receptor gamma coactiv

128 through suppression of hepatic expression of peroxisome proliferator activated receptor-gamma and gen

129 ssues, including estrogen receptor alpha and peroxisome proliferator activator beta and gamma, indica

130 pression of the steatogenic nuclear receptor peroxisome proliferator-activated gamma (PPARgamma) and

131 involved in the steatogenic nuclear receptor peroxisome proliferator-activated gamma (PPARgamma) path

132 Here we investigated the impact of the peroxisome proliferator-activated receptor (PPAR) agonis

133 We hypothesized that bezafibrate, a broad peroxisome proliferator-activated receptor (PPAR) agonis

134 ption factors farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR) delta

135 Here we identify the nuclear receptor peroxisome proliferator-activated receptor (PPAR) delta

136 of SOD2 (superoxide dismutase 2), PGC1alpha [peroxisome proliferator-activated receptor (PPAR) gamma-

137 s, we identify circulating factors involving peroxisome proliferator-activated receptor (PPAR) pathwa

138 d mothers against decapentaplegic homologs), peroxisome proliferator-activated receptor (PPAR), and P

139 Activation of peroxisome proliferator-activated receptor (PPAR)-alpha

140 etion from hepatocytes in vivo downregulated peroxisome proliferator-activated receptor (PPAR)-alpha,

141 Peroxisome proliferator-activated receptor (PPAR)-delta

142 latter case, this involves up-regulation of peroxisome proliferator-activated receptor (PPAR)alpha e

143 , dipeptidyl peptidase 4 (DPP-4) inhibitors, peroxisome proliferator-activated receptor (PPAR-gamma/a

144 of genes related to fatty acid synthesis and peroxisome proliferator-activated receptor (PPARalpha) s

145 o the arylhydrocarbon receptor (AhR) and the peroxisome proliferator-activated receptor (PPARgamma);

146 Bezafibrate, a pan-peroxisome proliferator-activated receptor agonist, has

147 pression was enhanced by insulin-sensitizing peroxisome proliferator-activated receptor agonists and

148 dy was to investigate the protective role of peroxisome proliferator-activated receptor alpha (PPARal

149 PFAAs can activate transcription factor peroxisome proliferator-activated receptor alpha (PPARal

150 ansforming growth factor beta (TGF-beta) and peroxisome proliferator-activated receptor alpha (PPARal

151 ation, due to a reduced abundance of mRNA of peroxisome proliferator-activated receptor alpha (PPARal

152 Fenofibrate, a peroxisome proliferator-activated receptor alpha (PPARal

153 (TGF-beta)-regulated phospho-Akt (p-Akt) and peroxisome proliferator-activated receptor alpha (PPARal

154 iptome analysis identifies the lipid-sensing peroxisome proliferator-activated receptor alpha (PPARal

155 hepatic AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor alpha (PPARal

156 arnitine palmitoyltransferase 1A (CPT1A) and peroxisome proliferator-activated receptor alpha (PPARal

157 arvation, CREBH regulates and interacts with peroxisome proliferator-activated receptor alpha (PPARal

158 Peroxisome proliferator-activated receptor alpha (PPARal

159 sed expression were known to be regulated by peroxisome proliferator-activated receptor alpha (PPARal

160 or the nuclear receptor transcription factor peroxisome proliferator-activated receptor alpha (PPARal

161 activation of transcription factors such as peroxisome proliferator-activated receptor alpha (PPARal

162 Peroxisome proliferator-activated receptor alpha (PPARal

163 fasting, activation of the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARal

164 ardiac lipotoxicity, and discuss the role of peroxisome proliferator-activated receptor alpha and dys

165 ated by several nuclear receptors, including peroxisome proliferator-activated receptor alpha and/or

166 omatin immunoprecipitation assays identified peroxisome proliferator-activated receptor alpha as a me

167 nvolved in fatty acid beta-oxidation through peroxisome proliferator-activated receptor alpha phospho

168 anscription factors, particularly PPARalpha (peroxisome proliferator-activated receptor alpha), and l

169 to the increased transcriptional activity of peroxisome proliferator-activated receptor alpha, the tr

170 (S)-HDHA as a possible endogenous ligand for peroxisome proliferator-activated receptor alpha.

171 a-oxidation: fibroblast growth factor 21 and peroxisome proliferator-activated receptor alpha.

172 for the farnesoid X receptor (FXR) and dual peroxisome proliferator-activated receptor alpha/delta (

173 or-activated receptor-alpha (PPARalpha), and peroxisome proliferator-activated receptor beta/delta (P

174 The peroxisome proliferator-activated receptor delta (PPARD)

175 The nuclear hormone receptor peroxisome proliferator-activated receptor delta (PPARde

176 The peroxisome proliferator-activated receptor gamma (PPAR-g

177 Pharmacological activation of peroxisome proliferator-activated receptor gamma (PPAR-g

178 The peroxisome proliferator-activated receptor gamma (PPAR-g

179 homeostasis, epithelial hypoxia derived from peroxisome proliferator-activated receptor gamma (PPAR-g

180 ified ETS translocation variant 4 (ETV4) and peroxisome proliferator-activated receptor gamma (PPARG)

181 alus) and blue whale (Balaenoptera musculus) peroxisome proliferator-activated receptor gamma (PPARG)

182 he HFCF diet, WT mice displayed up-regulated peroxisome proliferator-activated receptor gamma (Pparg)

183 ere, we tested this hypothesis on three NRs: peroxisome proliferator-activated receptor gamma (PPARga

184 und 3a that possesses weak proadipogenic and peroxisome proliferator-activated receptor gamma (PPARga

185 ow GIP-R expression can be regulated through peroxisome proliferator-activated receptor gamma (PPARga

186 nd profiling of photoswitchable agonists for peroxisome proliferator-activated receptor gamma (PPARga

187 pid metabolism genes during NAFLD, including peroxisome proliferator-activated receptor gamma (PPARga

188 -depleted mice, and conditional OPC-specific peroxisome proliferator-activated receptor gamma (PPARga

189 /enhancer-binding protein family members and peroxisome proliferator-activated receptor gamma (PPARga

190 Peroxisome proliferator-activated receptor gamma (PPARga

191 hat binds and activates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARga

192 d structures of nuclear receptors, including peroxisome proliferator-activated receptor gamma (PPARga

193 conformational ensemble of nuclear receptor peroxisome proliferator-activated receptor gamma (PPARga

194 to stimulate or inhibit the activity of the peroxisome proliferator-activated receptor gamma (PPARga

195 y isoflavone genistein, a natural agonist of peroxisome proliferator-activated receptor gamma (PPARga

196 Peroxisome proliferator-activated receptor gamma (PPARga

197 We report direct activation of the nuclear peroxisome proliferator-activated receptor gamma (PPARga

198 We report two crystal structures of peroxisome proliferator-activated receptor gamma (PPARga

199 n of master adipogenic transcription factors peroxisome proliferator-activated receptor gamma (PPARga

200 Peroxisome proliferator-activated receptor gamma (PPARga

201 ot BCRP transport activity were blocked by a peroxisome proliferator-activated receptor gamma (PPARga

202 duction of prostaglandin J2 (PGJ2) activates peroxisome proliferator-activated receptor gamma (PPARga

203 In LX-2 cells, FXR activation increased peroxisome proliferator-activated receptor gamma activit

204 , similar to TPHP, found that ciglitazone (a peroxisome proliferator-activated receptor gamma agonist

205 lated expression of the transcription factor peroxisome proliferator-activated receptor gamma and its

206 The peroxisome proliferator-activated receptor gamma coactiv

207 sis (uncoupling protein-1, deiodinase-2, and peroxisome proliferator-activated receptor gamma coactiv

208 Overexpression of coactivator peroxisome proliferator-activated receptor gamma coactiv

209 The peroxisome proliferator-activated receptor gamma coactiv

210 mitochondrial biogenesis regulatory protein peroxisome proliferator-activated receptor gamma coactiv

211 voluntary wheel running and muscle-specific peroxisome proliferator-activated receptor gamma coactiv

212 The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactiv

213 khead box transcription factors O (Foxo) and Peroxisome proliferator-activated receptor gamma coactiv

214 mitochondrial biogenesis, in particular via peroxisome proliferator-activated receptor gamma coactiv

215 e key regulator of mitochondrial biogenesis, peroxisome proliferator-activated receptor gamma coactiv

216 The expression levels of peroxisome proliferator-activated receptor gamma coactiv

217 The peroxisome proliferator-activated receptor gamma coactiv

218 triggers complex adaptive responses in which peroxisome proliferator-activated receptor gamma coactiv

219 Caffeine also increased peroxisome proliferator-activated receptor gamma coactiv

220 This coincided with decreased levels of peroxisome proliferator-activated receptor gamma coactiv

221 ssion, potentially through the regulation of peroxisome proliferator-activated receptor gamma coactiv

222 gnature genes uncoupling protein (UCP)-1 and peroxisome proliferator-activated receptor gamma coactiv

223 mitochondrial respiration between legs, but peroxisome proliferator-activated receptor gamma coactiv

224 ation) and increased promoter methylation of peroxisome proliferator-activated receptor gamma coactiv

225 A subset of melanomas display heightened peroxisome proliferator-activated receptor gamma coactiv

226 The nuclear peroxisome proliferator-activated receptor gamma has wel

227 or kappaB and NOS2, and an inhibition of the peroxisome proliferator-activated receptor gamma network

228 on of the glucose/lipid metabolism regulator peroxisome proliferator-activated receptor gamma was ass

229 m with 5-amino salicylic acid, a PPAR-gamma (peroxisome proliferator-activated receptor gamma) agonis

230 downstream transcription factors, PPARgamma (peroxisome proliferator-activated receptor gamma), and p

231 ammalian target of rapamycin or reactivating peroxisome proliferator-activated receptor gamma, an LAL

232 o the endoplasmic reticulum, down-regulating peroxisome proliferator-activated receptor gamma, and re

233 downregulating Ucp1 and Pgc1alpha genes via peroxisome proliferator-activated receptor gamma.

234 protein-1 (MURF1)-mediated ubiquitylation of peroxisome proliferator-activated receptor gamma2 (PPARg

235 tein expressions of extracellular matrix and peroxisome proliferator-activated receptor pathways in s

236 the first week due to failure to undergo the peroxisome proliferator-activated receptor signaling-dep

237 ed attenuation of phagocytosis-induced PPAR (peroxisome proliferator-activated receptor) expression.

238 KLF5 (Kruppel-like factor-5) and PPARalpha (peroxisome proliferator-activated receptor) that regulat

239 h TGFbeta1 for receptor binding, while PPAR (peroxisome proliferator-activated receptor)-beta/delta a

240 (FoxO), AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor-alpha (PPAR-a

241 palmitoylethanolamide (PEA), a lipid-derived peroxisome proliferator-activated receptor-alpha (PPAR-a

242 receptor-y coactivator 1-alpha (PGC-1alpha), peroxisome proliferator-activated receptor-alpha (PPARal

243 EA-m could be correlated at least in part to peroxisome proliferator-activated receptor-alpha activat

244 uction of nitrate to NO and independently of peroxisome proliferator-activated receptor-alpha.

245 CD36 fine-tuned mitochondrial fitness via peroxisome proliferator-activated receptor-beta signalin

246 elpar is a potent, selective agonist for the peroxisome proliferator-activated receptor-delta (PPAR-d

247 Exogenous AC caused an increase in peroxisome proliferator-activated receptor-gamma (PPAR-g

248 Peroxisome proliferator-activated receptor-gamma (PPARga

249 Peroxisome proliferator-activated receptor-gamma (PPARga

250 Nuclear receptor peroxisome proliferator-activated receptor-gamma (PPARga

251 (TZD) antidiabetic drugs, which activate the peroxisome proliferator-activated receptor-gamma (PPARga

252 Evidence suggests that targeting Peroxisome Proliferator-Activated Receptor-gamma (PPARga

253 or (ER)-, glucocorticoid receptor (GR)-, and peroxisome proliferator-activated receptor-gamma (PPARga

254 EFs show increased expression of PGC-1alpha (peroxisome proliferator-activated receptor-gamma coactiv

255 lso show increased expression of PGC-1alpha (peroxisome proliferator-activated receptor-gamma coactiv

256 dismutase 2 (SOD2), and increased levels of peroxisome proliferator-activated receptor-gamma coactiv

257 a Silent information regulator 1 (SIRT1) and peroxisome proliferator-activated receptor-gamma coactiv

258 that 3-oxo-C12-HSL attenuates expression of peroxisome proliferator-activated receptor-gamma coactiv

259 ion of mitochondrial biogenesis (PGC-1alpha [peroxisome proliferator-activated receptor-gamma coactiv

260 (NFAT) and potentiated the transcription of peroxisome proliferator-activated receptor-y coactivator

261 s complex failed to alter, while blockade of peroxisome proliferator-activated receptors (PPARalpha,

262 he role of PPARgamma SIGNIFICANCE STATEMENT: Peroxisome proliferator-activated receptors (PPARs) are

263 Peroxisome proliferator-activated receptors (PPARs) are

264 Over the course of the past decade, peroxisome proliferator-activated receptors (PPARs) have

265 tor families retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs) hold

266 iptionally repress FAO genes, antagonists of peroxisome proliferator-activated receptors (PPARs), par

267 An isoform of peroxisome proliferator-activated receptors (PPARs), PPA

268 Given that some PFAS activate peroxisome proliferator-activated receptors (PPARs), we

269 th 14 other nuclear receptors, including the peroxisome proliferator-activated receptors (PPARs).

270 Dual activation of peroxisome proliferator-activated receptors alpha and de

271 cumulation in the intestine and up-regulates peroxisome proliferator-activated receptors alpha and ga

272 ation of the estrogen, aryl hydrocarbon, and peroxisome proliferator-activated receptors; and oxidati

273 s study was to determine whether downstream [peroxisome proliferator-activated-receptor alpha (PPARal

274 d suppression of systemic CCL2 production by peroxisome proliferator-activator receptor alpha (PPARal

275 otein [SREBP], acetyl-CoA carboxylase [ACC], peroxisome proliferator-activator receptors [PPARs], and

276 This process involves the activation of peroxisome protein activator receptor gamma (PPARgamma),

277 The mechanism of peroxisome protein import remains incompletely understoo

278 eful for further dissecting the mechanism of peroxisome protein import.

279 ulatory genes (maoc-1, dhs-28, daf-22) and a peroxisome-related gene (acox-3) were found to enlarge L

280 the impact of drought and heat stress on the peroxisomes remains unknown.

281 We show that Inp1 mediates peroxisome retention via an N-terminal domain that binds

282 ther cell cortex, suggesting a new model for peroxisome retention.

283 5), which localizes to both mitochondria and peroxisomes, reverses post-translational lysine acylatio

284 With a primary role in lipid metabolism, peroxisomes share a niche with lipid droplets within the

285 , reduced oil body mobilization and enlarged peroxisomes suggest compromised beta-oxidation.

286 a subclass of peroxisomes, named "anaerobic" peroxisomes that shift the current paradigm and turn att

287 These cells are rich in mitochondria and peroxisomes, the two organelles that mediate fatty acid

288 ates fatty acid (FA) trafficking from LDs to peroxisomes through two interrelated mechanisms.

289 troduce a complete mevalonate pathway in the peroxisome to convert acetyl-CoA to several commercially

290 loit the unusually large size of Arabidopsis peroxisomes to demonstrate that peroxisomes have extensi

291 atory substrates, promotes the transition of peroxisomes to glyoxysomes, and enhances the retention o

292 litating virus-host interactions that rewire peroxisomes to support cellular processes for virus repl

293 ow that Hansenula polymorpha Inp1 associates peroxisomes to the plasma membrane.

294 However, peroxisome transport requires minimal force output, and

295 Although peroxisomes typically are considered to consist of a sin

296 Pex5 binds to peroxisomes via a docking complex containing Pex14, and

297 uents, particularly damaged mitochondria and peroxisomes, which are major sources of oxidative stress

298 ondria is frequently associated with loss of peroxisomes, which compartmentalize pathways that genera

299 terminus is important for association to the peroxisome, while a stretch of conserved positive charge

300 An improved understanding of peroxisomes will be important not only to the understand