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1 al membrane proteins, which are required for peroxisome biogenesis.
2 pastoris is characterized by a deficiency in peroxisome biogenesis.
3 or, one of at least 15 peroxins required for peroxisome biogenesis.
4 t PpPas2p is involved in the early stages of peroxisome biogenesis.
5 Our data show that VPS13D regulates peroxisome biogenesis.
6 MARCH5 is central for mitochondria-dependent peroxisome biogenesis.
7 nd plasmalogens, the ER also plays a role in peroxisome biogenesis.
8 chloroplast biogenesis, SP1 plays a role in peroxisome biogenesis.
9 two AAA-ATPases that play a crucial role in peroxisome biogenesis.
10 of Pex1/Pex6 and dynamin-related proteins in peroxisome biogenesis.
11 n are induced in oleate and coordinated with peroxisome biogenesis.
12 f the phosphoprotein ScPex11p coincides with peroxisome biogenesis.
13 ction, YCL056c, and Pex proteins involved in peroxisome biogenesis.
14 at indicate a defect in lipid metabolism and peroxisome biogenesis.
15 eins in addition to their canonical roles in peroxisome biogenesis.
16 tion is independent of its role at the ER in peroxisome biogenesis.
17 n of genes required for lipid metabolism and peroxisome biogenesis.
18 the requirements of early and late events of peroxisome biogenesis.
19 r peroxisome-induction conditions, impairing peroxisome biogenesis.
20 enetically defined as proteins necessary for peroxisome biogenesis.
21 ional assays to identify genes with roles in peroxisome biogenesis.
22 g peroxisomal proteins and genes involved in peroxisome biogenesis.
23 61-related gene, SSH1, also has no effect on peroxisome biogenesis.
24 hat loss of Sec61p activity has no effect on peroxisome biogenesis.
25 respiratory deficiency dramatically induces peroxisome biogenesis.
26 more than 20 PEX genes that are required for peroxisome biogenesis.
27 roxisomes and does not inhibit PEX3-mediated peroxisome biogenesis.
28 PBD cell lines are shaping current models of peroxisome biogenesis.
29 a peroxisomal protein (peroxin) involved in peroxisome biogenesis.
30 l enzyme abnormalities as well as defects of peroxisome biogenesis.
31 hat Pex4p and Pex22p act at the same step in peroxisome biogenesis.
32 g that Pex19p functions at an early stage of peroxisome biogenesis.
33 vel and implies a role for these vesicles in peroxisome biogenesis.
34 f genes required for glycerol metabolism and peroxisome biogenesis.
35 ythms were aligned with 12-h oscillations in peroxisome biogenesis and activity, reactive oxygen spec
36 in growth on fatty acids, one is involved in peroxisome biogenesis and at least two are required for
37 drome, and with car1, a protein required for peroxisome biogenesis and caryogamy in the filamentous f
39 ganelles has implications for all aspects of peroxisome biogenesis and function and may help address
40 ion of the PEX12 transcript exhibit impaired peroxisome biogenesis and function, inhibition of plant
44 In this review we focus on the genetics of peroxisome biogenesis and on how defects in this process
45 disorder characterized by severe defects in peroxisome biogenesis and peroxisomal protein import.
46 anding of players and mechanisms involved in peroxisome biogenesis and peroxisome degradation, very f
48 psis thaliana) PEX12 protein is required for peroxisome biogenesis and plays an essential role throug
49 nd energy metabolism, while also influencing peroxisome biogenesis and proliferation, thereby exempli
50 epithelial cell differentiation upregulates peroxisome biogenesis and promotes robust type III inter
51 ta demonstrate an important role for PEX1 in peroxisome biogenesis and suggest that mutations in this
52 PEX6 form a complex of central importance to peroxisome biogenesis and that mutations affecting this
55 TGF-beta1 signaling down-regulated not only peroxisome biogenesis but also the metabolism of these o
56 s a protein required for the early stages of peroxisome biogenesis, but its precise function and site
58 (RCDP) is an autosomal recessive disease of peroxisome biogenesis characterized by deficiencies in s
59 sicle coat-assembly, centrosomes, autophagy, peroxisome biogenesis, cytoskeleton, ribosome maturation
60 pared to wild-type PEX6 c.2578C results in a peroxisome biogenesis defect and thus constitutes the ca
62 wo novel schemes for the direct selection of peroxisome-biogenesis-defective (pex) mutants of the met
63 eas some of these proteins are stabilized in peroxisome biogenesis deficiency models lacking MARCH5 e
65 odysplasia punctata (RCDP), a severe, lethal peroxisome biogenesis disorder characterized by aberrant
66 3 or [1-14C]22:5n-3 to DHA as did cells from peroxisome biogenesis disorder patients comprising eight
67 l and diseased (Pex7 deficiency modeling the peroxisome biogenesis disorder, RCDP) mouse brain tissue
72 defects in peroxisome assembly result in the peroxisome biogenesis disorders (PBDs), a group of genet
76 sponsible for complementation group 8 of the peroxisome biogenesis disorders and showed that it encod
77 stabilization as a therapeutic strategy for peroxisome biogenesis disorders arising from the G843D m
79 utations in PEX5 or 12 other PEX genes cause peroxisome biogenesis disorders, collectively named the
86 causes of a spectrum of autosomal-recessive peroxisome-biogenesis disorders (PBDs), including Zellwe
88 sive disorders that are caused by defects in peroxisome biogenesis due to bi-allelic mutations in any
89 ons, including membrane fusion, proteolysis, peroxisome biogenesis, endosome sorting and meiotic spin
92 Seed 1 (SSE1) gene encodes a homolog of the peroxisome biogenesis factor Pex16p, and a loss-of-funct
93 d sustained neuroinflammatory responses with peroxisome biogenesis factor suppression despite limited
95 investigated host neuroimmune responses and peroxisome biogenesis factors during severe acute respir
96 ontology categories: fatty acid degradation, peroxisome biogenesis, fatty acid synthesis, and retinol
98 mutants, we isolated a viable allele of the peroxisome biogenesis gene PEX13 with striking peroxisom
99 this report we demonstrate the induction of peroxisome biogenesis genes in both plant and animal cel
100 tor, Mxr1 activates methanol utilization and peroxisome biogenesis genes in the methylotrophic yeast,
104 plications, we recast mechanisms controlling peroxisome biogenesis in a framework that integrates inf
108 induced peroxisomal biogenesis, and abnormal peroxisome biogenesis in MARCH5/Pex14 and MARCH5/Pex3 dk
110 cytosolic location, PEX26- delta ex5 rescues peroxisome biogenesis in PEX26-deficient cells as effici
113 es the progress made in our understanding of peroxisome biogenesis in the last few years, during whic
114 rt the cloning of PER6, a gene essential for peroxisome biogenesis in the methylotrophic yeast Pichia
115 amily, PpPex1p and PpPex6p, are required for peroxisome biogenesis in the yeast Pichia pastoris.
116 ral membrane peroxins (proteins required for peroxisome biogenesis) in Saccharomyces cerevisiae, Pex2
117 Refsum disease, and five of the disorders of peroxisome biogenesis, including rhizomelic chondrodyspl
118 d growth on oleic acid, but had no effect on peroxisome biogenesis, indicating a role for YLR284C in
119 which the model can be used to conclude that peroxisome biogenesis is dominated by de novo production
122 udy of phosphatases and kinases required for peroxisome biogenesis is the first genome-wide analysis
123 of peroxisomal matrix proteins, crucial for peroxisome biogenesis, is mediated by the cytosolic rece
124 our studies reveal a novel role for Lrp1 in peroxisome biogenesis, lipid homeostasis, and OPC differ
125 , none are known, leading us to propose that peroxisome biogenesis may not require protein import int
129 f the approximately 20 proteins required for peroxisome biogenesis, only four have been implicated in
132 nol pathway enzymes and proteins involved in peroxisome biogenesis (PEX proteins) are induced in resp
140 ic reticulum (ER) plays an important role in peroxisome biogenesis; some peroxisomal membrane protein
141 me fission factors, leading us to infer that peroxisome biogenesis switches from de novo synthesis to
142 elated yeast peroxins (proteins required for peroxisome biogenesis) that are partially redundant in f
143 proteins (mostly peroxins) are required for peroxisome biogenesis, the role of only a few of these h
144 sing on transcriptional networks that induce peroxisomes biogenesis, the model-guided experiments all
145 s of evidence support a function for SSE1 in peroxisome biogenesis: the peroxisomal localization of a
146 has permitted categorization of disorders of peroxisome biogenesis, their molecular basis and mutatio