ライフサイエンスコーパス: persistent

1 ch may be high or low titer and transient or persistent.

2 One patient had a persistent 5-degree head tilt and a small chin up that w

3 g successive stress episodes before reaching persistent abnormal levels.

4 Persistent accumulation of damaged mitochondria has been

5 or therapies that can arrest and reverse the persistent accumulation of disabilities associated with

6 However, the mechanisms underlying the persistent accumulation of Mo/MPhi remain poorly underst

7 bserved gender gap in collections was highly persistent across years in practice, subspecialty, and g

8 ardiac hypertrophy and heart failure through persistent activation of mTOR.

9 ioning relies on mechanisms that differ from persistent activity accounts of working memory.

10 The significant risk factors for persistent activity at 3 months were male gender (odds r

11 imaging of VMHdm(SF1) neurons revealed that persistent activity at the population level reflects het

12 f duration in that chamber, stress increases persistent activity of this projection, which correlates

13 s neuronal memory mechanism does not rely on persistent activity, excitatory feedback, or synaptic pl

14 igate two distinct cortical activity states: persistent activity, in which compartmentalized network

15 d that both AMPARs and NMDARs contributed to persistent activity.

16 aptic plasticity (STSP) without the need for persistent activity.

17 the importance of strategies for maintaining persistent adherence to PrEP and novel approaches to mak

18 class I, 53.6%) followed by drug refractory, persistent AF (class I, 41.8%).

19 om 121 patients with persistent/long-lasting persistent AF (group 1; 59 males; 60+/-11 years; 91 mitr

20 : The Vein of Marshall Ethanol for Untreated Persistent AF (VENUS) trial was an investigator-initiate

21 ommon comorbidity (67.6%), and patients with persistent AF had more comorbidities than patients with

22 us endo-epi phase mapping of prolonged human persistent AF recordings shows significant Endocardial-e

23 Patients (N = 350) with persistent AF referred for first ablation were enrolled

24 lled consecutive patients with paroxysmal or persistent AF who underwent cryoballoon pulmonary vein i

25 Patients with persistent AF<2 years were included.

26 ong critically ill surgical sepsis patients, persistent AKI and the absence of renal recovery are ass

27 Thus, persistent alteration of eCB signaling after repeated se

28 An early and persistent alteration of glial cell activity takes place

29 erinatal glucocorticoid exposure resulted in persistent alteration of the hypothalamic-pituitary-adre

30 Tributyltin (TBT) is a persistent and bioaccumulative environmental toxicant.

31 s acute toxicity and be less environmentally persistent and bioaccumulative.

32 The relative distributions of persistent and diffusive migration can be changed by mod

33 Persistent and impaired inflammation impedes tissue heal

34 ness compared to the CA for the treatment of persistent and long-standing persistent atrial fibrillat

35 ss of endocardial catheter ablation (CA) for persistent and long-standing persistent atrial fibrillat

36 for international regulatory mechanisms for persistent and mobile organic contaminants (PMOCs) that

37 minant of bacterial biofilms responsible for persistent and nosocomial infections.

38 es of indole signalling have been described: persistent and pulse.

39 Persistent and saturated oxygen distribution from perfus

40 Cyclic reactivation of these MBs through persistent antigen exposure favors their clonal expansio

41 Here, we show that persistent antigenic stimulation impaired ADP-coupled ox

42 I in cases where the cause of extraction was persistent apical periodontitis (35.7%), but this increa

43 (INCS) remain the preferred monotherapy for persistent AR, but additional studies support the additi

44 or Ebola virus, and a small number developed persistent arthralgia.

45 utrophilic inflammatory cell infiltrate, and persistent arthritis, via GM-CSF production, as deletion

46 for 24 hours from 10 patients with moderate, persistent asthma and 10 matched, nonallergic controls,

47 We recruited 156 children with severe persistent asthma and controls for nasal transcriptome p

48 Among children with persistent asthma and low vitamin D levels, vitamin D3 s

49 mended as the preferred therapy for moderate persistent asthma in step 3 (low-dose ICS-formoterol the

50 Ss) has been reserved for patients with more persistent asthma.

51 Catheter ablation of persistent atrial fibrillation (AF) has limited success.

52 lation (CA) for persistent and long-standing persistent atrial fibrillation (AF) treatment led to the

53 (Pulsed Fields for Persistent Atrial Fibrillation [PersAFOne]; NCT04170621)

54 alcohol) per week and who had paroxysmal or persistent atrial fibrillation in sinus rhythm at baseli

55 patient cohort included 55 paroxysmal and 21 persistent atrial fibrillation patients undergoing eithe

56 A total of 333 enrolled persistent atrial fibrillation patients underwent ablati

57 In persistent atrial fibrillation, a positive correlation w

58 he treatment of persistent and long-standing persistent atrial fibrillation.

59 tigen to T cells, and potentially initiate a persistent autoimmune response against the heart.

60 ow that CeA-LH projections are important for persistent avoidance of stress-related stimuli following

61 failure (TF), defined as 30-day mortality or persistent bacteremia >=7 days.

62 -10 was elevated in mortality (P = .008) and persistent bacteremia (P = .034), while no difference oc

63 (difference, 4.5%; 95% CI, -3.7% to 12.7%); persistent bacteremia at day 5 was observed in 19 of 166

64 The difference in persistent bacteria between in vitro and human sputum pr

65 The persistent bacteria in sputum was 17% of the in vitro le

66 nised by the host's innate immune system and persistent BDG antigenaemia, in the absence of IFD, can

67 Testing after training showed a persistent bias in attention in the expected directions.

68 says on 5 years of field samples that showed persistent but highly variable frequencies of aphid clon

69 Cocaine-associated memories are persistent, but, on retrieval, become temporarily destab

70 n the brain parenchyma of infected mice with persistent CD11b(+) microglia/macrophages in the inflame

71 EGFR) mutant non-small-cell lung cancer is a persistent challenge in cancer therapy.

72 ission in the ecology of epidemics remains a persistent challenge.

73 tients with CKD have limitations, leading to persistent challenges in the detection and monitoring of

74 During adulthood, stress unmasked persistent changes in DHPG-induced LTD and behavior that

75 ng may induce such long-term effects through persistent changes in the DNA methylome, which therefore

76 tes a subset of cells that undergo off-line, persistent chemical and/or physical changes to become an

77 substances (PFAS) are a group of widely used persistent chemicals with suspected immunotoxic effects.

78 o date, prior studies have focused on legacy persistent chlorinated pollutants (POPs), while the effe

79 nd postnatal week associated with abnormally persistent cholinergic innervation.

80 secondary helminth infection on the basis of persistent (chronic) HBV infection increased HBV-specifi

81 h lower all-cause mortality risk, even among persistent clean fuel users (HR 0.78, 0.69-0.89).

82 frequently) at baseline were categorised as persistent clean fuel users, previous solid fuel users,

83 Our findings suggest that the persistent cohesion protects short telomeres from inappr

84 bacterial factors are known to contribute to persistent colonization of this niche, and many are impo

85 nce clinical and scientific understanding of persistent concussion symptoms.

86 a exposure is associated with a more severe, persistent course of affective and anxiety symptoms.

87 abetic macular edema (DME) or postvitrectomy persistent cystoid macular edema (P < .05).

88 e pregnane X receptor helped in overcoming a persistent cytochrome P450 3A4 induction problem.

89 LE mice had a significant and persistent decrease in type 3 innate lymphoid cells (ILC

90 in infants of mothers in the antepartum and persistent depression trajectories (6% and 2% of women,

91 ation (hazard ratio 1.38, 95% CI 1.27-1.51), persistent deprivation (1.77, 1.62-1.93), or loss or thr

92 adipose tissue and hepatic development, and persistent diet-responsive transcriptional changes.

93 BCP after RARP and to evaluate the sites of persistent disease on PSMA PET/CT.

94 equiring repeated intraocular injections for persistent disease.

95 ients show a protracted clinical course with persistent disease.

96 Persistent DME was present in 50.8 and 31.6% of the 190

97 es have been argued to be the consequence of persistent drug use.

98 developed competent state was prolonged and persistent during pneumonia-derived sepsis.

99 Persistent dysphotopsia after cataract surgery is a sign

100 rse analysis revealed that MOE10-29 had more persistent effects than PMO10-29.

101 hat ZIKV-infected infant rhesus macaques had persistent enlargement of lateral ventricles, smaller vo

102 is study included 18 patients with NK with a persistent epithelial defect or corneal ulcer, treated w

103 for severe dry eye disease and 4 studies of persistent epithelial defect.

104 These changes provoke a state of persistent ER stress that has been demonstrated to gover

105 fields in the US Corn Belt was explained by persistent factors and identified the underlying drivers

106 These findings may explain the persistent failure of NK cell therapy in patients with s

107 ounter-reaction or conventional electrolyte, persistent faradaic current peaks dominate the IV cycle

108 Persistent fever and gastrointestinal symptoms are the m

109 ical pneumonia characterized by a dry cough, persistent fever, and progressive dyspnea and hypoxia, s

110 d that NMDARs are particularly important for persistent firing because they exhibit long time constan

111 impaired aged animals also exhibited reduced persistent firing capacity, which may contribute to agin

112 of the membrane potential allows to generate persistent firing when clusters of cooperative channels

113 e presence of clinical PARPi, suggesting the persistent foci are not caused by physical stalling.

114 e potential role of PFA beyond paroxysmal to persistent forms of AF.

115 regimens due to its particular action on the persistent forms of Mycobacterium tuberculosis However,

116 We show here that persistent FOXM1 expression following drug treatment is

117 o, we tested whether rapamycin could improve persistent function after release of obstruction (de-obs

118 dritic planetary body, bridging a previously persistent gap in differentiation processes from icy com

119 Thus, persistent gut antigens select recurrent BCR clonotypes

120 estigate the effects of a low FODMAP diet on persistent gut symptoms, the intestinal microbiome, and

121 (all completing 48 weeks of follow-up) with persistent HBsAg seroconversion.

122 tinuing to treat with monthly injections for persistent HE in the absence of macular thickening.

123 sts that the risk of violence was higher for persistent heavy users (odds ratio=2.81, 95% CI=1.68, 4.

124 Accumulating evidence indicates that persistent Helicobacter pylori gastric infection influen

125 indicators should be monitored closely, and persistent high levels of acute-phase reactants should r

126 evident sex differences in the frequency of persistent HIV in resting CD4 T cells.

127 nhance the effectiveness of interventions in persistent hotspots of transmission.

128 ds (OR: 0.35, 95% CI 0.14-0.89, p = 0.03) of persistent hrHPV compared to women with Lactobacillus de

129 of Lactobacillus species was associated with persistent hrHPV infection in HIV-negative women but not

130 ationship between the vaginal microbiota and persistent hrHPV was modified by HIV status.

131 We also discuss the mechanism of persistent HRP2 positivity after effective antimalarial

132 In healthy individuals, immune control of persistent human cytomegalovirus (HCMV) infection is eff

133 The knowledge that persistent human papillomavirus (HPV) infection is the m

134 l vein occlusion (CRVO) as a complication of persistent hyaloid artery (PHA).

135 rench Registry who had C3 glomerulopathy and persistent hypocomplementemia.

136 presentation of antigens, and induction of a persistent immune response.

137 cient in DC cross-priming are protected from persistent immune-mediated myocardial damage and decline

138 t; (5) failed social reconstruction; and (6) persistent impaired multidimensional symptoms extending

139 ell restoration, and are associated with the persistent impairment of lung function in individuals wi

140 e, an antiepileptic massively prescribed and persistent in water, which had been described to interac

141 Brief female exposure induces a persistent increase in male aggressiveness, an effect ab

142 Here, we showed that a small, persistent increase in the abundance of the innate patho

143 Several disorders present reflex or persistent increase in vagal tone that may cause refract

144 disease may be associated with a modest but persistent increased long-term mortality risk.

145 ances (PFASs) are a class of environmentally persistent industrial compounds that disrupt various met

146 patients demonstrating resolution (n = 35), persistent infection (n = 14) or de novo rejection (n =

147 criptional alterations from those induced by persistent infection and the need for selection and immo

148 tiviral immunity to establish and maintain a persistent infection may lead to the development of new

149 The noninfectious status may represent persistent infection, since Chlamydia genomes proliferat

150 ad of the acquired immune response, enabling persistent infection.

151 e deficient for establishment of latency and persistent infection.

152 Persistent infections are often associated with mutant s

153 ate the establishment of rapidly-propagating persistent infections within-host.

154 reus evades the neutrophil response to cause persistent infections.

155 ry during the early phases of tissue repair, persistent inflammation contributes to fibrosis.

156 Low-grade persistent inflammation is a feature of diabetes-driven

157 This model phenotypically recapitulates the persistent inflammation, immunosuppression, and cataboli

158 However, this would translate to omnipresent persistent inflammation.

159 oth biotic and abiotic (pH) treatments had a persistent influence on the development of fungal commun

160 rmometer" circuit that provides powerful and persistent inhibition to brain centers involved in regul

161 ing, consistent with its role in mediating a persistent interaction with Par-3.

162 hesis by predicting time to maximum yield of persistent intermediates for a particular set of rate co

163 command-like control of courtship song and a persistent internal state of social arousal mediated by

164 CMV is an obligate and persistent intracellular pathogen that continually drive

165 rophages, NK cells, and neutrophils mediates persistent joint inflammation via production of IL-18 an

166 ed after DVT, but are encouraged if there is persistent leg swelling or if a trial of stockings impro

167 bile duct with potential for recurrence and persistent local growth.

168 left atrial biopsies from 121 patients with persistent/long-lasting persistent AF (group 1; 59 males

169 t, lung, or pancreatic cancer, CEACAM5 was a persistent longitudinal outlier as early as 26.5 months

170 uring differentiation, epigenetic memory and persistent looping are maintained at a subset of Pax7 en

171 sease phenotype was not immediately obvious, persistent low levels of the protein eventually resulted

172 eft with neurological sequelae and some with persistent, low-level viral replication in the CNS.

173 t time proposed an MIs-triggered ratiometric persistent luminescence (R-PersL) sensor array for the d

174 Persistent luminescence depends on the electronic proper

175 tudied the chemistry involving dual-emission persistent luminescence nanoparticles (D-PLNPs) with met

176 In a mouse model of persistent lymphocytic choriomeningitis virus (LCMV) inf

177 unds termed cycloparaphenylenes (CPPs)-shape-persistent macrocycles with built-in cavities and radial

178 sites confirmed BAF is a fast, accurate, and persistent mark of nucleus rupture whose kinetics are pa

179 mains unclear whether macrophages retain any persistent memory of past polarization states which may

180 ully to salvage 11 cases (6 endocarditis) of persistent methicillin-susceptible Staphylococcus aureus

181 ngue with <=20 000 platelets/muL and without persistent mild bleeding or any severe bleeding in a pos

182 le those isolated from untreated animals had persistent mitochondrial hyperpolarization.

183 tor (median attachment duration <0.2 s) to a persistent motor that sustains attachment (median attach

184 ental evidence for 3HP-mediated clearance of persistent Mtb infection in human lungs has not been est

185 mal threats impaired extinction efficacy via persistent multivariate representations of conditioned l

186 FNs, mediated viral control during acute and persistent MuPyV encephalitis.

187 ive forces, and trajectories of transient or persistent mutations and genome rearrangements.

188 ndex of 6.3 +/- 4.1 kg/m(2) in patients with persistent NASH vs reduction of 13.4 +/- 7.4 kg/m(2); P

189 stocompatibility complex II upregulation and persistent natural killer (NK) cell cytolytic killing.

190 Persistent neural activity in cortical, hippocampal, and

191 xidative stress pathways, and a reduction in persistent neurodegenerative processes.

192 Although the mechanism(s) involved with persistent neurological deficits is not fully known, mit

193 Persistent neuronal spiking has long been considered the

194 ate stages of tendon repair, suggesting that persistent NF-kappaB signaling may facilitate myofibrobl

195 The prepared molecules present a persistent nonplanar framework and are soluble in a wide

196 The development of new persistent opioid use after surgery is a common complica

197 However, patients with persistent opioid use had sustained increases in spendin

198 Other risk factors for new persistent opioid use included receiving a larger opioid

199 criber's opioid prescribing behavior impacts persistent opioid use is unclear.

200 Patients without persistent opioid use returned to baseline health care s

201 Persistent opioid use was also associated with older age

202 ents who underwent inpatient procedures, new persistent opioid use was associated with health care sp

203 nts who underwent outpatient procedures, new persistent opioid use was similarly correlated with high

204 tainty evidence suggested increased risk for persistent opioid use with past or current substance use

205 ernia repair, 1.5% of patients developed new persistent opioid use.

206 In this cohort, 8103 patients developed persistent opioid use.

207 ion scores over multiple time points and new persistent opioid use.

208 The presence of persistent or increasing BDG in the patient's circulatio

209 stent organic pollutants (so-called "legacy" persistent organic pollutants (POPs)) and a synthetic mi

210 rsus maritimus) are highly contaminated with persistent organic pollutants (POPs).

211 des via a wide range of routes, such as some persistent organic pollutants (POPs).

212 one receptor beta (THRB), when exposed to 14 persistent organic pollutants (so-called "legacy" persis

213 fluoroalkyl substances (PFAS) are widespread persistent organic pollutants and endocrine disruptors.

214 roalkyl substances (PFAS) are an ensemble of persistent organic pollutants of global interest because

215 Bs), a globally prevalent group of regulated persistent organic pollutants, commonly couple chemical

216 king, and biomarkers of chemical pollutants (persistent organic pollutants, metals, phthalates, pheno

217 was limited to a reduced number of targeted persistent organic pollutants, reaching open waters main

218 ositive correlation among BKPyV integration, persistent overexpression of viral large T antigen (TAg)

219 individual valued life goals in the face of persistent pain, and further improvements in pain treatm

220 Thus, we propose that the persistent PARP1 foci are formed by different PARP1 mole

221 ajor downstream effector of PAR, also caused persistent PARP1 foci without affecting PARP1 exchange.

222 However, many persistent pathogens, such as Mycobacterium tuberculosis

223 ammatory syndrome in individuals who develop persistent pathological responses to parenchymal injury

224 play an important role in the development of persistent PH and survival after PEA.

225 battery is a quantum device that provides a persistent phase bias to the wave function of a quantum

226 o the F-region, and that they are a related, persistent phenomenon.

227 disorder have been defined, it is unknown if persistent phosphate wasting in nephropathic cystinosis

228 These ultraviolet-C persistent phosphors can be effectively charged by a sta

229 mposite of all-cause mortality, dementia, or persistent physical disability.

230 activity is not sufficient but necessary for persistent physiological activity, implying an essential

231 While loss of the persistent polar trophoblast in mice leads to reduced in

232 roalkyl substances (PFAS) are widespread and persistent pollutants that have been shown to have hepat

233 The persistent population displayed sustained activation fol

234 to a lesser extent, evergreen forests show a persistent positive asymmetry, whilst (natural) grasslan

235 onditions, such as low back pain, arthritis, persistent post-surgical pain, fibromyalgia, and neuropa

236 opioid use before surgery are vulnerable to persistent postoperative opioid use.

237 The primary outcome was "new persistent postoperative opioid user," was defined as a

238 for circumventing sensor fouling, which is a persistent problem for electrochemical dopamine sensors.

239 Persistent protein obstacles on genomic DNA, such as DNA

240 undergone primary radiotherapy, and 70 had a persistent PSA elevation after receiving initial treatme

241 bnormalities are present early in youth with persistent psychosis risk symptoms, however, there is li

242 However, persistent pulmonary hypertension (PH) after PEA remains

243 repares the organ for strong, efficient, and persistent pumping throughout the mammal's lifespan.

244 Persistent PVN was associated with an increased risk for

245 Persistent R-loops (RNA-DNA hybrids with a displaced sin

246 (REM) sleep regulates emotional memory, and persistent REM sleep impairment after cocaine withdrawal

247 75% receiving BOT 1.0 mg twice daily were in persistent remission compared with 4.4% of patients in t

248 uary to harbor HIV and maintains chronic and persistent replication within the CNS.

249 arriage over the study period, there is high persistent residual carriage.

250 Persistent respiratory morbidity a priori defined as a r

251 to our knowledge, to suggest a prevalence of persistent respiratory morbidity and the association bet

252 cteristics of mechanical ventilation predict persistent respiratory morbidity at follow-up.

253 Persistent rhinitis was associated with male gender, pat

254 High and persistent rotavirus shedding among vaccinated children

255 Herein, we report the first persistent RTP with lifetimes up to 0.5 s from simple tr

256 Persistent severe airway obstruction despite massive dos

257 limbic system and beyond interact to produce persistent shifts in affective states.

258 nt pathways enable both rapid activation and persistent signaling in receptor-mediated RhoA signaling

259 To understand the mechanisms of persistent skin inflammation in DOCK8 deficiency, we exa

260 ion of wake after sleep onset and latency to persistent sleep from baseline to days 1 and 2 with dari

261 Persistent smoking may cause adverse outcomes among pati

262 ed land-atmosphere coupling, associated with persistent soil moisture deficit, appears to intensify s

263 an fuel users, previous solid fuel users, or persistent solid fuel users, according to self-reported

264 pressing excitatory currents that drive more persistent spiking.

265 chitecture that improve our understanding of persistent staphylococcal infections.

266 rpolarization and depolarization both induce persistent static elevation of cytoplasmic calcium level

267 articipation of cerebellar structures in the persistent storage of visual information.

268 ohorts of infants showed an elevated risk of persistent stunting from 12 through 24 months with a rel

269 LDS classification is based on the report of persistent, subjective symptoms for >= 6 months followin

270 characteristics and self-reported acute and persistent symptoms were assessed using a standardized d

271 ified patients is effective in patients with persistent symptoms.

272 Using LTD as a readout of persistent synaptic consequences of stress, our findings

273 ice with either of two genetically distinct, persistent T. gondii strains (Prugniaud/type II/haplogro

274 Also, persistent tags working in bright environments are not a

275 In conclusion, anal HPV-16 is more persistent than HPV-18, and its incidence correlates wit

276 ervention embedded during extinction reduces persistent threat responses.

277 wed the formation of solid coagula that were persistent throughout gastric digestion, which caused a

278 dentification of extreme IOD variability and persistent tropical Indo-Pacific climate coupling-may ha

279 ptation, phenocopying the human heart defect persistent truncus arteriosus (PTA), which trunk neural

280 Explorative analyses also showed persistent tuning to the threat cue in higher visual are

281 acute illness to chronic disease, based on a persistent type 2 immune response to respiratory infecti

282 Mechanistically, persistent upregulation of the HBP triggers decompensate

283 hases of addiction: (i) downward spiral into persistent use and (ii) relapse.

284 clinical characteristics and any use and new persistent use of opioids.

285 to the United States opioid epidemic through persistent use past the postoperative period.

286 The rate of persistent use was slightly higher than for matched non-

287 ospital discharge, and 2.6% met criteria for persistent use, an average of 300 new persistent users p

288 mpared with patients who did not develop new persistent use.

289 mpared with patients who did not develop new persistent use.

290 ia for persistent use, an average of 300 new persistent users per year in a population of 14 million.

291 (31 [30%]), rebound viraemia (55 [53%]), and persistent viraemia (18 [17%]).

292 ruses found in humans and is prototypic of a persistent viral infection characterized by periods of l

293 xact contribution to the outcome of acute or persistent viral infections has remained elusive.

294 storing exhausted CD8(+) T cell responses in persistent viral infections or tumors.

295 hat, in contrast to an acute viral strain, a persistent viral isolate leads to long-term viral replic

296 isorders remain prevalent potentially due to persistent viral replication, production of viral protei

297 ical battery converts chemical energy into a persistent voltage bias that can power electronic circui

298 identify common principles of resistance and persistent vulnerabilities to overcome resistance.

299 a higher likelihood of LDEs, suggesting that persistent weather conditions will occur more frequently

300 ion, CDK1 fails to activate, possibly due to persistent WEE1 activity, which blocks lamina phosphoryl