ライフサイエンスコーパス: persistent infection

1 n have a significant impact on the nature of persistent infection.

2 lerate exposure to antibiotics, resulting in persistent infection.

3 an persist to yield potentially untreatable, persistent infection.

4 diagnostic agreement, despite FFV causing a persistent infection.

5 ant viruses may be the forms responsible for persistent infection.

6 bacteria to overcome host restriction during persistent infection.

7 glycoproteins of NDV in the establishment of persistent infection.

8 arance or in mitigating the fitness costs of persistent infection.

9 hers control the pathogen as an asymptomatic persistent infection.

10 o escape host immune clearance and establish persistent infection.

11 cating the presence of a tissue reservoir of persistent infection.

12 s its derivative, clone 13 (Cl-13), causes a persistent infection.

13 hat vIL-10 may play a functional role during persistent infection.

14 bud from the plasma membrane and establish a persistent infection.

15 ic treatment for the prolonged duration of a persistent infection.

16 V evades host adaptive immunity to establish persistent infection.

17 that are maintained in their rodent hosts by persistent infection.

18 n for replication in macaques to establish a persistent infection.

19 gens to evade immune clearance and establish persistent infection.

20 nge of clinical presentations and a lifelong persistent infection.

21 e virus in the establishment of a long-term, persistent infection.

22 rus-induced cardiac disease during acute and persistent infection.

23 in response to hypoxia in vivo, resulting in persistent infection.

24 t support a potential role in primary and/or persistent infection.

25 r phagosomes of the host cells and establish persistent infection.

26 ly important hepatitis B and C viruses cause persistent infection.

27 specimens obtained from subjects developing persistent infection.

28 Ten recipients developed prolonged or persistent infection.

29 elope proteins from HBV in order to maintain persistent infection.

30 ad of the acquired immune response, enabling persistent infection.

31 E, which contributes to the establishment of persistent infection.

32 reliosis in patients presenting disseminated persistent infection.

33 esistance, antibiotic treatment failure, and persistent infection.

34 ic variants to escape immunity and establish persistent infection.

35 that promotes evasion of neutralization and persistent infection.

36 lm-induced changes in host physiology during persistent infection.

37 = 1.00), respectively, for the diagnosis of persistent infection.

38 (Msp2) outer membrane variants to establish persistent infection.

39 FN-gamma) was assessed during both early and persistent infection.

40 tures; both have low sensitivities to detect persistent infection.

41 e deficient for establishment of latency and persistent infection.

42 to escape the immune response, resulting in persistent infection.

43 pecific approach for treating KSHV lytic and persistent infection.

44 erapeutic vaccine or aid in the diagnosis of persistent infection.

45 t of Q fever, can result in life-threatening persistent infection.

46 reus evades the neutrophil response to cause persistent infections.

47 S. aureus associated with SCV generation and persistent infections.

48 comes a more complex issue in the context of persistent infections.

49 ction detection, but cannot reliably predict persistent infections.

50 ifferentiation is not clear, particularly in persistent infections.

51 eath, thereby promoting the establishment of persistent infections.

52 ral approaches to probe the small numbers in persistent infections.

53 ppeared to be contagious and associated with persistent infections.

54 asive fungi can impair clearance and promote persistent infections.

55 osure with implications for cancer and other persistent infections.

56 mediate a stable standoff during controlled persistent infections.

57 h similar but nonsignificant HRs for 6-month persistent infections.

58 biofilms are responsible for a wide range of persistent infections.

59 med to identify risk factors associated with persistent infections.

60 tunistic pathogen that can cause devastating persistent infections.

61 nsing, prevent biofilm formation and control persistent infections.

62 y 10 to 20% of infections are established as persistent infections.

63 induce a protective immune response against persistent infections.

64 as been documented, leading to nonpathogenic persistent infections.

65 itopes in E2 remained intact throughout both persistent infections.

66 clinical symptoms associated with new versus persistent infections.

67 ions having a greater inhibitory effect than persistent infections.

68 linical episodes, independent of presence of persistent infections.

69 any cases, facilitating the establishment of persistent infections.

70 validated targets that allow eradication of persistent infections.

71 4; 95% confidence interval, 1.3-1.5) than to persistent infections.

72 To establish a persistent infection,A. baumannii must overcome the detr

73 ey B cells in vitro and reproduces acute and persistent infection after oral inoculation of macaques.

74 itro, and successfully established acute and persistent infection after oral inoculation of rhesus ma

75 intrahost evolution of EAV during acute and persistent infection and demonstrate that persistent inf

76 To distinguish reinfection from persistent infection and detect potential transmission c

77 squitoes have evolved mechanisms to tolerate persistent infection and developed efficient antiviral s

78 nique hysteretic memory switch may result in persistent infection and enhanced host-to-host spreading

79 egy and is required for the establishment of persistent infection and for viral spread to additional

80 gulates CD8(+) T cell differentiation during persistent infection and have implications toward optimi

81 IL-1beta was able to establish a significant persistent infection and immune activation in BALB/c mic

82 nced ability to replicate in mice and caused persistent infection and immune activation in the BALB/c

83 Hepatitis C virus (HCV) often causes persistent infection and is an increasingly important fa

84 other mammals, but are described as causing persistent infection and lacking pathogenicity.

85 ntained after therapy-induced elimination of persistent infection and may constitute an important tar

86 KV targets the testis in males, resulting in persistent infection and oligospermia.

87 associated herpesvirus (KSHV) cause lifelong persistent infection and play causative roles in several

88 Host responses during persistent infection and preneoplastic stages can shape

89 T cells that sustain T cell responses during persistent infection and proliferate upon anti-PD1 treat

90 rategies are complicated by evidence of both persistent infection and reinfection of people with prio

91 typically similar during early resolving and persistent infection and secreted similar levels of cyto

92 LRV1-positive patients (27%) presented with persistent infection and symptomatic relapse that requir

93 at suboptimal Ag presentation contributes to persistent infection and that limiting Ag presentation i

94 criptional alterations from those induced by persistent infection and the need for selection and immo

95 t this is a bacterial adaptation to maximize persistent infection and transmission to a new host unde

96 ed by Brucella to establish an intracellular persistent infection and will aid in the development of

97 As the possible exception, VEs against persistent infection and/or CIN 2/3 due to HPV-31 A/B an

98 18, -31, -33, -35, -45, and -51 resulting in persistent infection and/or CIN 2/3 were matched (ratio,

99 reprogram host cells to establish long-term persistent infection and/or to produce viral progeny.

100 y disease had a chronic clinical course with persistent infections and death.

101 y disease has a chronic clinical course with persistent infections and death.

102 ersister-like cells that have been linked to persistent infections and discuss their impact on therap

103 ationships of viruses that are able to cause persistent infections and exist with high incidences of

104 ay have an intrinsic ability to cause highly persistent infections and later adverse outcomes.

105 s a potential good diagnostic marker for MAP persistent infections and predictor of disease specific

106 otential new target for the immunotherapy of persistent infections and should be accounted for and su

107 ividual cells (as endogenous retroviruses or persistent infection) and multicellular organisms (as ei

108 90% reduction of incident infection, 6-month persistent infection, and ASCUS+, respectively.

109 This may contribute to the mechanism of HCV persistent infection, and suggest that blockade of HCVc

110 of Msp2 variants expressed during long-term persistent infection are mosaics, derived by recombinati

111 In some cases, these persistent infections are asymptomatic for long periods

112 Persistent infections are common, and there is currently

113 Because repeated or persistent infections are correlated with serious compli

114 Persistent infections are often associated with mutant s

115 mechanisms associated with establishment of persistent infections are poorly elucidated.

116 ng many vertebrates, including humans, whose persistent infections are problematic for aquaculture an

117 lococcus aureus biofilms, a leading cause of persistent infections, are highly resistant to immune de

118 In persistent infection, arginase-expressing gMDSCs (and ci

119 ssue and ACS sonication culture in detecting persistent infection, as well as their association with

120 n persist in large numbers during controlled persistent infections, as exemplified by rare HIV-infect

121 mal disease at cutaneous sites but developed persistent infection at the mucosal sites including thos

122 Diagnosis of persistent infection at the time of reimplantation for s

123 Thirteen subjects deemed not to have persistent infection at time of reimplantation and who h

124 molecule that can operate in defense against persistent infection at times when other innate control

125 such modified vectors were able to establish persistent infection but lost their ability to reactivat

126 1 year before infection (204 incident and 64 persistent infections), but we observed no consistent di

127 s, such as Epstein-Barr virus, can establish persistent infection, but the underlying virus-host inte

128 infections might be due to reactivation of a persistent infection, but this hypothesis has been diffi

129 approximately 2000 years ago as a result of persistent infection by a fungal endophyte, Ustilago esc

130 is required for B. burgdorferi to establish persistent infection by continually evading otherwise po

131 oprotein of hepatitis C virus contributes to persistent infection by evolving escape mutations that a

132 HVR1 contributes to persistent infection by evolving mutations that escape f

133 regions of HCV genomes appear to facilitate persistent infection by masking the genome from RNase L

134 Persistent infection by specific oncogenic human papillo

135 Results here confirm the establishment of persistent infection by SVA and demonstrate successful t

136 This persistent infection can cause severe disease in immunoc

137 ght to be important in the dissemination and persistent infection caused by ranavirus.

138 ble-stranded DNA viruses that cause lifelong persistent infections characterized by periods of quiesc

139 Persistent infection (chronic Q fever) develops in 1%-5%

140 ed in a cohort of 22 individuals treated for persistent infection (chronic Q fever) whether they reco

141 work in the murine norovirus (MNV) model of persistent infection demonstrates that innate immunity c

142 s) are associated with unusually chronic and persistent infections despite active antibiotic treatmen

143 Many bacterial pathogens cause persistent infections despite repeated antibiotic exposu

144 cobacterium tuberculosis (Mtb) establishes a persistent infection, despite inducing antigen-specific

145 esented the hallmarks of S. aureus linked to persistent infection: down-regulation of virulence genes

146 tifies a similar proportion of patients with persistent infection during staged revisions, as detecte

147 letion of genes from the wca operon caused a persistent-infection E. coli strain to become sensitive

148 Microbes that cause persistent infections (e.g., herpes viruses) do so by sw

149 Furthermore, during persistent infection, extensive genome-wide purifying se

150 In fact, persistent infections following antibiotic treatment are

151 ibular salivary gland (SMG), a major site of persistent infection for many viruses, contains a large

152 ient-derived hepatitis B virus can establish persistent infection for over 30 days in a self-assembli

153 Here, we show that NPHV, like HCV, can cause persistent infection for over a decade, with high titers

154 eficiency virus type 1 (HIV-1) establishes a persistent infection for which there remains no feasible

155 Incident and 6-month persistent infections for HPV 6 and 11 did not differ by

156 Lifelong persistent infection has also been linked with the devel

157 fic CD4 T cells primed during an established persistent infection have diminished ability to develop

158 Prior studies in mouse models of persistent infection have suggested that ineffective ada

159 tramacrophage environment may be a niche for persistent infection; however, mechanisms by which the b

160 is, pathogens can proliferate and establish persistent infections if either the state of the microbi

161 Whereas immune-compromised mice developed persistent infection, immune-competent mice cleared the

162 Persistent infection, immunotolerance and early dissemin

163 V infection is that it establishes long-term persistent infection in 10 to 70% of infected stallions

164 We explore the emergence of persistent infection in a closed region where the diseas

165 However, E. coli has been shown to cause a persistent infection in a minority of cases.

166 LB/c, and C3H/HeN mice and induced lethal or persistent infection in a route- and dose-dependent mann

167 ewcastle disease virus (NDV) could establish persistent infection in a tumor cell line, resulting in

168 antibody neutralization contributing to FMDV persistent infection in African buffalo.IMPORTANCE Foot-

169 ies to hijack infected host cells, establish persistent infection in B cells, and evade antiviral imm

170 hagic fever in macaques but an asymptomatic, persistent infection in baboons.

171 in neonatal-infected mice diversified during persistent infection in both the brain and spleen, while

172 Biofilms facilitate colonization and persistent infection in gallbladders of humans and mouse

173 ubiquitous virus that establishes a lifetime persistent infection in humans.

174 Here, we demonstrated that DcRV induces persistent infection in its psyllid host, Diaphorina cit

175 found that CHIKV establishes and maintains a persistent infection in joint-associated tissue in part

176 ggest that CHIKV establishes and maintains a persistent infection in joint-associated tissue in part

177 of the lymphatic cell environment supporting persistent infection in Kaposi sarcoma tumors.

178 M. tuberculosis that allows establishment of persistent infection in lymph nodes.

179 persistence.IMPORTANCE Although CHIKV causes persistent infection in lymphoid and musculoskeletal tis

180 The inability to establish a persistent infection in mice, even in immunocompromised

181 Hepatitis C virus (HCV) establishes persistent infection in most infected patients, and even

182 They can be rapidly cleared in some, cause persistent infection in others, and cause mortality from

183 HIV-1 establishes persistent infection in part due to its ability to evade

184 wn as hepatitis delta virus) can establish a persistent infection in people with chronic hepatitis B,

185 re large-genome DNA viruses that establish a persistent infection in sensory neurons and commonly man

186 Here, we showed that SVA establishes persistent infection in SVA-infected animals, with the t

187 ctious by the intravenous route, established persistent infection in the B cell compartment, and elic

188 was required for MRSA to achieve high-level, persistent infection in the bladder.

189 JCPyV presents initially as a persistent infection in the kidneys of healthy people, b

190 mavirus (JCPyV) establishes an asymptomatic, persistent infection in the kidneys of the majority of t

191 may also contribute to the establishment of persistent infection in the liver.

192 Hepatitis C virus (HCV) causes persistent infection in the majority of infected individ

193 emiological and clinical features, including persistent infection in the male reproductive tract and

194 Dogmatically, B. burgdorferi can establish a persistent infection in the mammalian host (e.g., mice)

195 DeltacheY2-infected ticks did not develop a persistent infection in the murine host.

196 This loop sustains persistent infection in the presence of the immune activ

197 full MCMV infectivity in macrophages and for persistent infection in the salivary gland.

198 mia suggest the ability of ZIKV to establish persistent infection in the seminiferous tubules, an imm

199 genomic evolution during acute and long-term persistent infection in the stallion reproductive tract

200 ed with the establishment and maintenance of persistent infection in the stallion reproductive tract.

201 rus has the distinctive ability to establish persistent infection in the stallion's reproductive trac

202 including severe congenital manifestations, persistent infection in the testes, and neurologic seque

203 small DNA virus that establishes a life-long persistent infection in the urinary tract of most people

204 that plays an essential role in establishing persistent infection in their respective host species.

205 g human pathogens maintained by noncytolytic persistent infection in their rodent reservoir hosts.

206 cific responses and why they fail to prevent persistent infection in this model.

207 that is consistent with the establishment of persistent infection in tissue macrophages.

208 Thus, establishment of persistent infection in vitro involves viral genetic cha

209 coma-associated herpesvirus (KSHV) establish persistent infections in B cells.

210 omaviruses are characterized by establishing persistent infections in healthy hosts and generally cau

211 onotic simian foamy viruses (SFVs) establish persistent infections in humans, for whom the long-term

212 t the surprising finding that during ongoing persistent infections in mice, a major fraction of the p

213 y feature of viruses that establish lifelong persistent infections in the face of strong immune respo

214 re zoonotic viruses that cause asymptomatic, persistent infections in their rodent hosts but can lead

215 ommon cause of infectious mononucleosis, and persistent infection is associated with multiple cancers

216 Antimicrobial treatment of persistent infection is challenging.

217 nd persistent infection and demonstrate that persistent infection is characterized by extensive genom

218 or therapy in immunocompromised persons with persistent infection is limited because of cost, determi

219 heck-point function of the spleen to promote persistent infection is not clear.

220 iological agent of Lyme borreliosis, is that persistent infection is the rule in its many hosts.

221 How such enteric viruses establish persistent infections is not well understood.

222 mechanism of biofilm infection that leads to persistent infection lies in the capacity of biofilms to

223 tiviral immunity to establish and maintain a persistent infection may lead to the development of new

224 Such persistent infections may provide the opportunity for th

225 murine cytomegalovirus (MCMV) was used as a persistent infection model to study heterologous immunit

226 patients demonstrating resolution (n = 35), persistent infection (n = 14) or de novo rejection (n =

227 o spontaneously cleared HCV (n = 285) or had persistent infection (n = 509).

228 Other potential causes of persistent infection need to be evaluated.

229 Persistent infection occurred in 26% of cases.

230 Persistent infection of hepatitis C virus (HCV) is one o

231 may have evolved to allow HBoV1 to establish persistent infection of human airway epithelia.

232 ising in the viral capsid protein VP1 during persistent infection of mice.

233 Several studies have reported persistent infection of monocytes in virally suppressed

234 a human oncogenic virus, which maintains the persistent infection of the host by intermittently react

235 HIV-1 causes a persistent infection of the immune system that is associ

236 We detected persistent infections of Mycoplasma ovipneumoniae, the p

237 Despite this, SCVs are associated with persistent infections of the bloodstream, bones, and pro

238 iasis (CMC) is characterized by recurrent or persistent infections of the skin, nail, oral, and genit

239 ndpoint was vaccine efficacy against 6-month persistent infection or cervical intraepithelial neoplas

240 r efficacy, vaccine efficacy against 6-month persistent infection or CIN1+ associated with HPV 16/18

241 ons in the motif may present routes to clear persistent infections or limit immunopathology.

242 comparing temporally dispersed isolates from persistent infections (persistent isolates) originating

243 Of these 15 patients, 3 died from persistent infection postoperatively, whereas 8 underwen

244 ic CD4 T cells primed during the established persistent infection provide help to B cells, but only l

245 ambda (IFN-lambda)-mediated clearance during persistent infection requires the viral nonstructural pr

246 nd Ab-mediated immunity to control acute and persistent infection, respectively.

247 following an RC treatment (RCT) can lead to persistent infections, resulting in treatment failure an

248 The noninfectious status may represent persistent infection, since Chlamydia genomes proliferat

249 Deletion of genes in the wca operon from a persistent-infection strain resulted in a reduction of m

250 accumulates mutations at higher rates during persistent infections than other mycobacteria.

251 gulation of metabolic processes during early persistent infection that was linked to changes in expre

252 rmation on indwelling medical devices causes persistent infections that cannot be cured with conventi

253 us or human herpesvirus 8 (HHV-8), establish persistent infections that cause chronic illnesses, incl

254 Despite the importance of noncoding RNAs in persistent infection, the circRNA class of noncoding RNA

255 To maintain a persistent infection, the expression of ap2-g is limited

256 indeed EBV-2 utilizes T cells to establish a persistent infection, this could provide one mechanism f

257 ology during RCT has the potential to reduce persistent infections through vital cell detection and a

258 g acute infection, the role of vIL-10 during persistent infection was analyzed in rhesus macaques inf

259 Persistent infection was associated with increased and s

260 In contrast, persistent infection was asymptomatic and led to establi

261 that clear infection and those that develop persistent infection was demonstrated to occur earlier t

262 nonstochastic nature of EAV evolution during persistent infection was driven by active intrahost sele

263 CAR3) with a recombinant low-pathogenic NDV, persistent infection was established in a subset of tumo

264 Persistent infection was observed in all cases.

265 Using the J-Lat 10.6 model of persistent infection, we demonstrate that proliferation

266 macrophages ex vivo Using a mouse model for persistent infection, we demonstrate that Tat is require

267 Persistent infections were acquired at an earlier age, a

268 demonstrated that E. coli strains that cause persistent infections were more motile than those that c

269 limited by reduced antigen expression during persistent infection, whereas ESAT-6-specific T cells be

270 viral genome into the host cell, leading to persistent infection wherein HIV-1 can remain transcript

271 negligible CD8 T cell response, and caused a persistent infection, while v2.2 generated cytotoxic T l

272 n worldwide, predominantly originates from a persistent infection with a high-risk human papillomavir

273 lidity of results of attempts to demonstrate persistent infection with B. burgdorferi has not been es

274 Due to the high prevalence of persistent infection with BKV in the general population,

275 This first persistent infection with cell culture-produced HCV prov

276 Persistent infection with gammaherpesviruses (gammaHV) c

277 Liver disease associated with persistent infection with hepatitis B virus (HBV) contin

278 Persistent infection with hepatitis C virus (HCV) causes

279 shed that chronic antigen stimulation during persistent infection with hepatitis C virus is associate

280 Persistent infection with high-risk human papillomavirus

281 Persistent infection with high-risk human papillomavirus

282 nt cross-protective efficacy against 6-month persistent infection with HPV 31 (65.8%, 96.2% CI 24.9-8

283 Cervical cancer is a consequence of persistent infection with human papillomaviruses (HPV).

284 Mathematical models have predicted long-term persistent infection with low levels of periodic sheddin

285 Immune control of persistent infection with Mycobacterium tuberculosis (Mt

286 Persistent infection with oncogenic Human Papillomavirus

287 uman lymphocytes survive while maintaining a persistent infection with species C adenovirus, we compa

288 n innate immune responses are susceptible to persistent infection with variable manifestations of his

289 nd immune pathology associated with acute or persistent infections with an unrelated virus.

290 Persistent infections with cytomegalovirus (CMV) differe

291 ociated with sex, birth characteristics, and persistent infections with cytomegalovirus (CMV) or EBV.

292 Persistent infections with hepatitis B virus (HBV) or he

293 fundamentally in their ability to establish persistent infections with markedly different patterns o

294 i infection display features common to other persistent infections with signs of T cell exhaustion.

295 of that ST in that herd (index case) and all persistent infections with that PTE ST, represented 40%

296 monovalent type 3 OPV seroresponse than did persistent infections, with enterovirus detected at both

297 e samples as a result of niche adaptation to persistent infection within a host.

298 ict pathogens, some viruses have established persistent infections within parasitoid wasp lineages an

299 ate the establishment of rapidly-propagating persistent infections within-host.

300 f Staphylococcus aureus disease in humans is persistent infections without development of protective