ライフサイエンスコーパス: phagocytic cell

1 d efficient antigen presentation in the host phagocytic cell.

2 s replace CCR2(+) macrophages as the primary phagocytic cell.

3 more efficient at killing and escaping these phagocytic cells.

4 y selective retention within macrophages and phagocytic cells.

5 taken up by peritoneal macrophages and other phagocytic cells.

6 uoG mutant spread to a larger number of lung phagocytic cells.

7 ession of rhsT was induced upon contact with phagocytic cells.

8 athogen that invades both phagocytic and non-phagocytic cells.

9 ectin-3), a gene typically expressed only in phagocytic cells.

10 ), modulate essential interactions with host phagocytic cells.

11 ) is a catalytic subunit of NOX expressed in phagocytic cells.

12 h apoptotic cells are cleared from tissue by phagocytic cells.

13 neration of reactive oxygen species (ROS) in phagocytic cells.

14 polarization, and activation of mononuclear phagocytic cells.

15 with the presence of alternatively activated phagocytic cells.

16 increased transferrin receptor expression by phagocytic cells.

17 ptake, and killing of many microorganisms by phagocytic cells.

18 (iNOS) in the innate response of mononuclear phagocytic cells.

19 tion of extensive retraction was specific to phagocytic cells.

20 leading to C3b opsonization and ingestion by phagocytic cells.

21 tion of the major exosporium protein BclA by phagocytic cells.

22 lem of intracellular survival, especially in phagocytic cells.

23 mulatory beta-glucans from detection by host phagocytic cells.

24 hanism that controls IFN-gamma production by phagocytic cells.

25 ype K1 CPS elicits chemokine production from phagocytic cells.

26 targets for complement receptors present on phagocytic cells.

27 tion between Gram-negative bacteria and host phagocytic cells.

28 xidative antimicrobial molecules produced by phagocytic cells.

29 HSV-induced infiltration of tumor-associated phagocytic cells.

30 les from superoxide that is released by host phagocytic cells.

31 esponse to spirochetal lysate stimulation of phagocytic cells.

32 via modulation of NADPH oxidase activity in phagocytic cells.

33 ocytic leukocytes, as well as in certain non-phagocytic cells.

34 es and has been found to persist inside host phagocytic cells.

35 fection by cell-to-cell spread from adjacent phagocytic cells.

36 ed by Abeta(42) to chemoattract and activate phagocytic cells.

37 the ultimate fate of B. bacteriovorus inside phagocytic cells.

38 crobial peptides, mucociliary clearance, and phagocytic cells.

39 the rituximab-CD20 complexes were removed by phagocytic cells.

40 respiration and exogenously produced by host phagocytic cells.

41 hogens that survive and multiply within host phagocytic cells.

42 udying the interaction of C. neoformans with phagocytic cells.

43 anism, possibly by improving survival within phagocytic cells.

44 g P. aeruginosa resistant to antibiotics and phagocytic cells.

45 by liver-, spleen-, and bone marrow-resident phagocytic cells.

46 defense mechanisms of macrophages and other phagocytic cells.

47 , suggesting a specificity of C5 cleavage by phagocytic cells.

48 e dying organism are engulfed by circulating phagocytic cells.

49 uent rapid elimination through the action of phagocytic cells.

50 to determine how rickettsiae survive within phagocytic cells.

51 ent activation, and appearance of defects in phagocytic cells.

52 obably mediates its effects via host-derived phagocytic cells.

53 the interactions between A. pittii and human phagocytic cells.

54 everal cell types, including mitotic and non-phagocytic cells.

55 amentous actin and altered actin dynamics in phagocytic cells.

56 lammasome, Th17 signaling and recruitment of phagocytic cells.

57 ction of Yersinia outer proteins (Yops) into phagocytic cells.

58 isingly, feedback inhibition is abrogated in phagocytic cells.

59 icity mediated by complement-fixing DSAs and phagocytic cells.

60 layer, particles of which can be ingested by phagocytic cells.

61 nd a specific viability deficit inside human phagocytic cells.

62 diabetic mice transfer secretory vesicles to phagocytic cells.

63 ed for activation of engulfment receptors on phagocytic cells.

64 osome-sensitive population of liver-resident phagocytic cells.

65 ins to efficiently and differentially target phagocytic cells.

66 y regulated genes were highly induced inside phagocytic cells.

67 anisms for fungal persistence and killing in phagocytic cells.

68 understanding of F. tularensis infection of phagocytic cells.

69 latum is a respiratory pathogen that infects phagocytic cells.

70 n debris that is usually promptly cleared by phagocytic cells.

71 isease (CGD) is a rare inherited disorder of phagocytic cells(1,2).

72 is their rapid recognition and engulfment by phagocytic cells (a process called efferocytosis).

73 antiinflammatory cytokine interleukin 10 by phagocytic cells after the apoptotic phase of the infect

74 eviously showed that impairment of recruited phagocytic cells allowed survival of ExoU-secreting P. a

75 l role in GAS resistance to human and murine phagocytic cells, allowing the bacteria to persist at th

76 However, many phagocytic cells also act as antigen-presenting cells an

77 nsmission of pathogenic mycobacteria between phagocytic cells also depends on nonlytic ejection throu

78 Phagocytic cells also express exPS, which is dependent o

79 of tumor infiltration with MMP-9 expressing phagocytic cells and a higher degree of coverage of endo

80 with IL-6 that can bind Fcgamma receptors on phagocytic cells and are rapidly internalized.

81 Neutrophils are phagocytic cells and are vital components in the human i

82 complement but not between an OPA using HL60 phagocytic cells and baby rabbit complement.

83 It is believed that survival within phagocytic cells and cell-to-cell spread via actin protr

84 important virulence factors that lyse human phagocytic cells and contribute to immune evasion.

85 by far the most abundant agent generated by phagocytic cells and may be the major mediator of inflam

86 family, NOX-2 (gp91(phox)), is expressed in phagocytic cells and mediates microbicidal activities.

87 Macrophages are myeloid-derived phagocytic cells and one of the first immune cell types

88 cation channel, inhibited ROS production in phagocytic cells and prevented endotoxin-induced lung in

89 d light on the interactions between NETs and phagocytic cells and provide new insights regarding the

90 nocytes, and T lymphocytes, in activation of phagocytic cells and release of granule-based enzymes an

91 plicate in professional and non-professional phagocytic cells and subvert immune responses for chroni

92 ges and it was defective for invasion of non-phagocytic cells and survival within macrophages; but it

93 te that Mac-1 expression is critical on both phagocytic cells and T cells for the development of demy

94 production elicited by B. burgdorferi Ags in phagocytic cells and the development of murine Lyme arth

95 een B. anthracis spores with nonprofessional phagocytic cells and thus direct the spores towards upta

96 ytic cell line HL-60 served as the source of phagocytic cells, and a commercial preparation of intrav

97 to electrostatically repel pneumococci from phagocytic cells, and avoidance of phagocytosis correlat

98 antly by activated dendritic cells (DCs) and phagocytic cells, and both cytokines induce IFN-gamma se

99 In tissues, fibroblasts are phagocytic cells, and in culture, they have been shown t

100 arkers (CD14, CD16, and CD172a), were potent phagocytic cells, and produced TNF in response to LPS.

101 cells secrete chemotactic factors to attract phagocytic cells, and we found that S1P potently stimula

102 he vascular endothelium, bone marrow-derived phagocytic cells are a major site of IgG homeostasis.

103 What has emerged from these studies is that phagocytic cells are essential for protection and that d

104 L. monocytogenes to invade non-professional phagocytic cells are not fully understood.

105 the clearance of such debris by mononuclear phagocytic cells are poorly understood.

106 ver, the molecular mechanism(s) by which the phagocytic cells are recruited in the PPT1-KO mouse brai

107 By analyzing the relative proportion of phagocytic cells as a function of cell cycle phase, we o

108 ant to phagocytosis by both murine and human phagocytic cells at levels comparable to those of flagel

109 pathogenesis of gas gangrene and the lack of phagocytic cells at the site of infection.

110 f a filter that separated them from the host phagocytic cells below.

111 receptor 1 (CR1) expressed on the surface of phagocytic cells binds complement-bound immune complexes

112 not inhibit S. aureus binding and uptake by phagocytic cells but instead attenuates S. aureus induce

113 Inflammation is mediated primarily by phagocytic cells, but the mechanisms of CNS tissue destr

114 onella pneumophila is able to survive inside phagocytic cells by an internalization route that bypass

115 gent of bacterial pneumonia, survives inside phagocytic cells by avoiding rapid targeting to the lyso

116 Depletion of phagocytic cells by clodronate liposomes in wild-type mi

117 ella enterica serovar Typhimurium invade non-phagocytic cells by injecting bacterial effector protein

118 In contrast, in vivo depletion of phagocytic cells by injection of liposomes containing cl

119 nation to the brain, an effect that required phagocytic cells, C1q, and FcgammaRIII (CD16).

120 Despite the presence of these phagocytic cells, chancroid ulcers can persist for month

121 c HL-60 cells, with exogenous PS resulted in phagocytic cell clearance, and this process was further

122 Recent studies have revealed that these phagocytic cells control the patterning and wiring of th

123 targeted up-regulation of Nox1 expression in phagocytic cells could provide a novel approach in the m

124 hypothesized that P4-mediated activation of phagocytic cells could rapidly and substantially increas

125 en these fungal cells are most vulnerable to phagocytic cell defenses.

126 killer cell-depleted, or carrageenan-treated phagocytic cell-depleted mice were inoculated with 4T1 a

127 hogens encounter numerous insults, including phagocytic cells designed to degrade bacteria, while est

128 ractions of live B. bacteriovorus with human phagocytic cells, determining the uptake mechanisms, per

129 D. melanogaster Schneider 2 phagocytic cells displayed decreased phagocytosis and ca

130 he cell-mediated immune system (by targeting phagocytic cells), disrupt epithelial barriers, and libe

131 erium that targets host alveolar mononuclear phagocytic cells during infection.

132 ur study demonstrated that HOCl generated by phagocytic cells during inflammatory episodes has a pote

133 (RNI), were used to investigate the role of phagocytic cells during mucosal and systemic candidiasis

134 conditions such as those encountered within phagocytic cells during the host immune response, iron i

135 in the brain is followed by infiltration of phagocytic cells (e.g. activated microglia, astroglia an

136 nes, and cellular immune defenses, including phagocytic cells (e.g., macrophages).

137 cterial numbers are low relative to those of phagocytic cells, e.g., early in an infection.

138 ease of innate immune-related molecules from phagocytic cells early in the course of infection.

139 us infections through its ability to promote phagocytic cell effector functions.

140 detect IL-6 and ED-1 (a marker of microglial/phagocytic cells), enzyme-linked immunosorbent assay (EL

141 These data indicate that phagocytic cells, especially lung macrophages, can gener

142 otic tumor nodules surrounded by mononuclear phagocytic cells, followed by fibrosis and calcification

143 ellite glial cell precursors are the primary phagocytic cells for apoptotic corpse removal in develop

144 suggesting that the pathogen may not target phagocytic cells for intracellular growth during natural

145 e a useful function in directing hemozoin to phagocytic cells for safe disposal.

146 In vitro, phagocytic cells from C3(+/+) or C3(-/-) mice exhibited

147 The phagocytic cells from MGL1(-/-) mice did not exhibit any

148 Depletion of phagocytic cells from normally developed spleens by trea

149 liferation of cyst-lining cells, we depleted phagocytic cells from Pkd1(fl/fl);Pkhd1-Cre mice by trea

150 bial pathogens and glycans on the surface of phagocytic cells from the host.

151 Although professional phagocytic cells harbor intracellular bacteria including

152 s found that the interaction between GXM and phagocytic cells has biological consequences that may co

153 While phagocytic cells have a requisite role in the response t

154 Reactive oxidative species (ROS) produced by phagocytic cells have been ascribed a role in the locali

155 e of persistent apoptotic-cell nuclei within phagocytic cells in nuc-1 mutants.

156 y of small GTPases play an essential role in phagocytic cells in organization of the actin cytoskelet

157 hese results highlight an unexpected role of phagocytic cells in processing T. gondii oocysts, in lin

158 ptococcus neoformans is poorly recognized by phagocytic cells in the absence of opsonins.

159 Microglia are phagocytic cells in the CNS and actively participate in

160 roglia are the principle immune effector and phagocytic cells in the CNS.

161 n of LRRK2 and its substrate Rab10 occurs in phagocytic cells in the immune system.

162 Kupffer cells (KC) are abundant phagocytic cells in the liver.

163 Our results indicate that phagocytic cells in the lung are injected with ExoU and

164 We determined that phagocytic cells in the lung were frequently injected wi

165 Because microglia, which are phagocytic cells in the mammalian brain, are bone marrow

166 e presence of C3-deficient serum compared to phagocytic cells in the presence of serum with sufficien

167 f outer segments, as well as the presence of phagocytic cells in the subretinal space.

168 readily taken up by both phagocytic and non-phagocytic cells in vitro after a short (approximately 3

169 ing in both liquid culture and within murine phagocytic cells in vitro and in vivo.

170 ting biocompatible nanoparticle that targets phagocytic cells in vivo and is coated with approximatel

171 has also been described in a variety of non-phagocytic cells, including cancer cells.

172 ind to different receptors on the surface of phagocytic cells, including the beta(2) integrin, comple

173 he causative agent of Lyme borreliosis, with phagocytic cells induces the activation of NF-kappaB and

174 Unlike resident phagocytic cells, inflammatory monocytes produced IL-12,

175 Previously, we found that phagocytic cells ingest bacteria directly from the cytos

176 Professional phagocytic cells ingest microbial intruders by engulfing

177 Phagocytic cells inhibit the growth of intracellular pat

178 transcription factors, such as NF-kappa B in phagocytic cells, initiate the proinflammatory cytokine

179 Macrophages, phagocytic cells involved in an early phase of host defe

180 Macrophages are specialized phagocytic cells involved in clearing invading pathogens

181 Microglia are phagocytic cells involved in homeostasis of the brain an

182 CvGal1 expressed by phagocytic cells is "hijacked" by the parasite Perkinsus

183 binding and uptake of B. anthracis spores by phagocytic cells is a dynamic process and involves multi

184 in the CNS, whose activation into migratory, phagocytic cells is associated with increased expression

185 nal IL-6 in retinal I/R injury in microglial/phagocytic cells is controlled predominantly by NF-kappa

186 e vaccine strain invasion of nonprofessional phagocytic cells is inhibited by cytochalasin D and noco

187 agents capable of increasing Abeta uptake by phagocytic cells is of potential therapeutic interest fo

188 e ability of this organism to survive inside phagocytic cells is poorly understood but thought to be

189 ryllus schlosseri, cell corpse engulfment by phagocytic cells is the recurrent mechanism of programme

190 CD47, a "don't eat me" signal for phagocytic cells, is expressed on the surface of all hum

191 so called CD11b/CD18), a beta(2) integrin on phagocytic cells, is one such receptor.

192 at the ability of S. aureus strains to evade phagocytic cell killing and to survive temporarily withi

193 eased bacterial clearance, and iv) increased phagocytic cell killing of bacteria compared with tail t

194 ammatory cells to the peritoneum, or improve phagocytic cell killing of pathogens.

195 PKH26-phagocytic cell labeling dye was administered intranasal

196 eveloping a cell-based immunotherapy using a phagocytic cell line, HL-60.

197 spread in L2 fibroblasts, a nonprofessional phagocytic cell line.

198 Clodronate-mediated depletion of phagocytic cells markedly prolonged the serum half-life

199 ells, which were also marked by a microglial/phagocytic cell marker (ED1) in the inner retina.

200 GS-9620 induced phagocytic cell maturation and improved effector-mediate

201 n the vascular circulation, erythrocytes and phagocytic cells may accumulate membrane lipid hydropero

202 of hosts with disseminated candidiasis, that phagocytic cells may play an active role in increasing t

203 I/R injury, and its expression by microglia/phagocytic cells may protect RGC layer neurons from I/R

204 Mononuclear phagocytic cells (MPCs), including macrophages and dendr

205 Phagocytic cell NADPH oxidase (NOX) generates reactive o

206 As the first-responder phagocytic cells, neutrophils are recruited in large num

207 While entry into macrophages and other phagocytic cells occurs constitutively, intracellular in

208 We discovered that Mtb infects phagocytic cells of diverse phenotypes, that the predomi

209 requirements for survival and replication in phagocytic cells of organisms from different kingdoms.

210 l role in the antimicrobial functions of the phagocytic cells of the immune system.

211 Hydrogen peroxide (H2O2) is used by phagocytic cells of the innate immune response to kill e

212 Phagocytic cells of the innate immune system appear to b

213 LRRK2 protein is highly expressed in phagocytic cells of the innate immune system, most notab

214 including alveolar macrophages, are primary phagocytic cells of the innate immune system.

215 n embryonic development OECs are the primary phagocytic cells of the primary olfactory nerve.

216 intracellular pathogen that persists within phagocytic cells of the reticuloendothelial system.

217 olism including the sequestration of iron in phagocytic cells of the reticuloendothelial system.

218 s, allowing them to survive and replicate in phagocytic cells of vertebrate hosts.

219 opsonophagocytic killing of staphylococci by phagocytic cells offers opportunities to establish such

220 d raises the fundamental question of how the phagocytic cell optimizes the acidification process to p

221 f LPS- and IAV-beads by different subsets of phagocytic cells or LPS-mediated differential activation

222 METH interferes with phagocytic cells' phagosomal maturation, resulting in im

223 nce demonstrates that macrophages, and other phagocytic cells, play a key role in regulating tumor gr

224 icroglia (MG), a heterogeneous population of phagocytic cells, play important roles in central nervou

225 Early in infection, phagocytic cells, predominantly neutrophils, are recruit

226 Macrophages are specialized phagocytic cells, present in all tissues, which engulf a

227 mia, plasma IL-6 concentrations, circulating phagocytic cell priming and pulmonary leukosequestration

228 ated kinetoplastid parasites that parasitize phagocytic cells, principally macrophages, of vertebrate

229 e inflammatory response, including activated phagocytic cells, pro- and anti-inflammatory cytokines,

230 but not epithelial cells or resident CD11b+ phagocytic cells, produced CCL2 in response to C. rodent

231 ygenation together with oxidants produced by phagocytic cells promote chronic oxidative stress within

232 Candidate phagocytic cell receptors responsible for the enhancemen

233 Macrophages and other phagocytic cells recognize and engulf these dead cells.

234 Phagocytic cell reduction in nitric oxide production dur

235 ging, PBSC were mixed with carbonyl iron and phagocytic cells removed with samarium cobalt magnets.

236 Defects in the phagocytic cells' respiratory burst lead to life-threate

237 r data suggest that the distinct mononuclear phagocytic cell response seen in cerebral X-ALD results,

238 ssion analysis by RNA sequencing of F4/80(+) phagocytic cells revealed activation of the activating t

239 eated mice confirmed that the elimination of phagocytic cells significantly reduces survival time and

240 the capacity to concentrate drug delivery to phagocytic cells, significantly reducing off-target toxi

241 y a key role in the bactericidal capacity of phagocytic cells such as macrophages and neutrophils.

242 In phagocytic cells such as macrophages, these pathogens mu

243 totic tissue is recognized for engulfment by phagocytic cells such as macrophages.

244 Phagocytic cells such as neutrophils and macrophages are

245 in contact with receptors on the surface of phagocytic cells such as neutrophils, monocytes/macropha

246 These results challenge the convention that phagocytic cells such as the microfold cells solely faci

247 tion between the infecting microorganism and phagocytic cells, such as macrophages.

248 ogen, Francisella survives and replicates in phagocytic cells, such as macrophages.

249 ctin was expressed by hemocytes, circulating phagocytic cells, suggesting a role for Drosophila galec

250 l association of blood-borne fungi with host phagocytic cells that are capable of killing the fungus.

251 Microglia are the resident mononuclear phagocytic cells that are critical for innate and adapti

252 Neutrophils are phagocytic cells that kill microorganisms but it is uncl

253 Macrophages are phagocytic cells that participate in the clearance of ap

254 LPS in murine microglial cells, the resident phagocytic cells that play a pivotal role in inflammator

255 Dendritic cells (DCs) are professional phagocytic cells that play an essential role in host def

256 Macrophages are a diverse population of phagocytic cells that reside in tissues throughout the b

257 ive production of reactive oxygen species in phagocytic cells that results in life-threatening infect

258 SLO and SLS were cytotoxic to epithelial and phagocytic cells that the bacteria would typically encou

259 ts into the signaling pathways in immune and phagocytic cells that underlie sepsis and SIRS and consi

260 ttern receptor recognition to recruitment of phagocytic cells-that occur during UPEC-mediated UTI.

261 the clearance of cell debris and bacteria by phagocytic cells, the role of CRP in additional immunolo

262 the bacterial surface and translocated into phagocytic cells; these cells subsequently underwent inf

263 C. neoformans has the capacity to escape phagocytic cells through a process known as nonlytic exo

264 CRP interacts with phagocytic cells through FcgammaRI and FcgammaRII and ac

265 nalization and intracellular survival within phagocytic cells thus may play an important role in the

266 e analogue inhibited the chemotaxis of human phagocytic cells to a number of formyl peptide receptor-

267 acterial infection depends on the ability of phagocytic cells to be recruited and properly activated

268 ed CD8 T cells secrete cytokines that induce phagocytic cells to engulf and kill bacterial pathogens.

269 ia, interferes with the ability of recruited phagocytic cells to eradicate bacteria from the lung.

270 ental processes or injury must be cleared by phagocytic cells to maintain and repair tissues.

271 n also be used with other phagocytic and non-phagocytic cells to study the individual or collective r

272 these signaling pathways to the response of phagocytic cells to the spirochete and the molecular mec

273 ponse to the interaction of spirochetes with phagocytic cells to TNF-alpha production.

274 idea that B cells evolved from an ancestral phagocytic cell type and provide an evolutionary framewo

275 tiation of metamorphosis and are the primary phagocytic cell type in the pupal neuropil.

276 mammalian brain glia, and identify the major phagocytic cell type responsible for engulfing degenerat

277 nts extends to epithelial cells, a minimally phagocytic cell type.

278 s-under (SIMU), which is expressed in highly phagocytic cell types during development and required fo

279 cantly more adherence to all nonprofessional phagocytic cell types.

280 ers in apoptotic cell clearance by different phagocytic cell types.

281 the phagolysosomes of neutrophils and other phagocytic cell types.

282 ar survival of S. aureus in non-professional phagocytic cells, via modulation of MazEF and Agr.

283 d the effect of this mutation on mononuclear phagocytic cells was examined.

284 In contrast, infection of phagocytic cells was not affected, leaving intact the ab

285 Internalization of BCG by phagocytic cells was shown to be significantly enhanced

286 bacterial mutant defective for growth within phagocytic cells was shown to be similarly defective for

287 Using PKH26-PCL to label resident phagocytic cells, we demonstrated that Gr-1 Macs were de

288 Bacterial ascent and the cell dynamics of phagocytic cells were assessed by biophotonic imaging an

289 cells (DCs) were ablated but failed when all phagocytic cells were depleted.

290 protein that is preferentially expressed by phagocytic cells, where it promotes efferocytosis and in

291 and undermines the health of these critical phagocytic cells, which can potentially interfere with t

292 , is involved in the handling of pristane by phagocytic cells, which is required to trigger disease i

293 o the malaria parasite from clearance by the phagocytic cells, which may be an immune escape mechanis

294 and molecular functions and may be deadly to phagocytic cells, which may result in increased suscepti

295 ighly immunogenic C. albicans hyphae attract phagocytic cells, which rapidly engulf adherent S. aureu

296 or macrophages in the thymus are regarded as phagocytic cells whose function is to clear apoptotic de

297 Thus, MSCs are novel phagocytic cells with a potential for immunotherapy in t

298 on remains unclear because prestimulation of phagocytic cells with microbial molecules is required fo

299 following bacterial internalization by host phagocytic cells with subsequent killing, using the enca

300 highly expressed in CD68(+) macrophages and phagocytic cells within tuberculosis lesions and that [(