ライフサイエンスコーパス: phenanthridine

1 iplatin, cis-[Pt(NH3)2(Am)Cl](+) where Am is phenanthridine.

2 ly known phenanthro[9',10':4,5]imidazo[1,2-f]phenanthridines.

3 ramolecular cyclization to yield substituted phenanthridines.

4 useful alternative for preparing substituted phenanthridines.

5 enant hridium chloride (NK314) is a benzo[c] phenanthridine alkaloid that inhibits topoisomerase IIal

6 Bioactive indolo[3,2-j]phenanthridine alkaloids Calothrixin A and B have been s

7 with the total synthesis of four oxybenzo[c]phenanthridine alkaloids, oxychelerythrine, oxysanguinar

8 lorine (2d), trispheridine (2b), and benzo[c]phenanthridines alkaloids dihydronitidine (3b), dihydroc

9 c approach for generating 7,8-dihydrobenzo[a]phenanthridine analogs through visible-light-induced cyc

10 n, thus offering an expeditious route to the phenanthridine and benzo[c]phenanthridine skeletons.

11 orted by frameworks containing benzannulated phenanthridine and quinoline heterocycles paired with am

12 intermediates in the biosynthesis of benzo[c]phenanthridine and rhoeadine derivatives.

13 A novel and efficient synthesis of phenanthridines and aza analogues is reported.

14 ns (aza-(P)AHs; namely, pyridine, quinoline, phenanthridine, and benzo[d]thiazole) is reported.

15 ymes in the metabolism of protopine, benzo[c]phenanthridine, and rhoeadine alkaloids.

16 Phenanthro[9',10':4,5]imidazo[1,2-f]phenanthridines are blue-emitters, and they exhibit stro

17 this photooxidative route toward substituted phenanthridines as well as makes clear predictions as to

18 The arylation products can be converted to phenanthridines by the reaction with trifluoroacetic anh

19 ated was phenanthriplatin, cis-[Pt(NH(3))(2)(phenanthridine)Cl]NO(3), which exhibits significantly gr

20 Starting from the nonsubstituted phenanthridine compound 4a, exhibiting a K(i) value of 5

21 Here we report on a phenanthridine derivative which has a covalently linked

22 med into highly sensitive 13,14-dehydrobenzo phenanthridine derivatives by HCl hydrolysis.

23 Metal-free synthesis of benzimidazole-fused phenanthridine derivatives was achieved in good to excel

24 the probe being over 5x brighter than other phenanthridine derivatives when bound to RNA.

25 erse cyclic/acyclic ketones, quinolines, and phenanthridine derivatives.

26 ting P^N ligand (L1) bearing a benzannulated phenanthridine donor arm.

27 nsfer efficiency from the fluorescein to the phenanthridine fluorophore is approximately 77%, which r

28 ee approach for the synthesis of substituted phenanthridines from the coupling reaction of aryldiazon

29 A robust synthesis of phenanthridines has been described via Pd(II)-catalyzed

30 iplatin, where Am is the N-heterocyclic base phenanthridine, has promising anticancer activity.

31 hriplatin, a cisplatin derivative containing phenanthridine in place of one of the chloride ligands,

32 cular arylation to provide the corresponding phenanthridines in moderate to excellent yields.

33 ynthesis of 7-bromobenzo[c]chromeno[4,3,2-gh]phenanthridines is reported using N-bromosuccinimide.

34 ng was observed for pyriplatin, in which the phenanthridine ligand of phenanthriplatin is replaced by

35 Rotation about the Pt-N bond of the phenanthridine ligand racemizes the complex, and the que

36 iplatin because of the hydrophobicity of the phenanthridine ligand.

37 A unified synthesis of phenanthridine natural products was also accomplished to

38 yliminyl radicals that proved convenient for phenanthridine preparations.

39 ze (acridine, psoralen, thiazole orange, and phenanthridine) produced DISHs with comparable moduli, b

40 Subsequent oxidative cyclization generates a phenanthridine product that is then reduced by atypical

41 reaction, such as isoquinolines, quinoline, phenanthridine, quinazoline, phthalazine, and beta-carbo

42 rt an aerobically stable Fe(II) complex of a phenanthridine/quinoline diarylamido ligand, Fe((Cl)L)(2

43 tion of N-heterocycles such as pyrrolidines, phenanthridines, quinoxalines, and quinazolinones.

44 involves rapid, partial intercalation of the phenanthridine ring followed by slower substitution of t

45 n the formation of the antimicrobial benzo[c]phenanthridine sanguinarine and certain rhoeadine alkalo

46 ious route to the phenanthridine and benzo[c]phenanthridine skeletons.

47 Syntheses of phenanthridines starting from 2-formylbiphenyls were par

48 1-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a] phenanthridine], the first high-affinity full D1 agonist

49 ized and shown to generate the corresponding phenanthridines upon irradiation in the presence of 9,10

50 heterocyclic backbone, benzo[k]pyrrolo[2,3-i]phenanthridine, via a tandem Suzuki reaction/nucleophili

51 benzo[d]imidazole to benzo[4,5]imidazo[1,2-f]phenanthridine was achieved at ~350 nm of irradiation vi

52 alideisoquinolines and antimicrobial benzo[c]phenanthridines were previously characterized.

53 r benzo-fused heterocycles (9H-carbazole and phenanthridine) when an aromatic amide anion is competit

54 xacyclic parnafungin C model decomposes to a phenanthridine with a half-life of 2 d in CDCl(3).

55 llows modular construction of functionalized phenanthridines with wide tolerance of electronic functi

56 clic heterocycles such as benzo[b]chromenes, phenanthridines, xanthenes, and spiroheterocyclic compou