ライフサイエンスコーパス: phenoloxidase

1 de of mostly unknown serine proteinases, and phenoloxidase.

2 as a common downstream protease to activate phenoloxidase.

3 re rapidly metabolized into intermediates by phenoloxidases.

4 riments to decrease the levels of individual phenoloxidases.

5 in in many arthropods, central importance of phenoloxidase, a copper enzyme in arthropods), the diffe

6 ole as a potent nanomolar-level inhibitor of phenoloxidase, a key component of the insect's innate im

7 y inhibited activation of M. sexta hemolymph phenoloxidase, a pathway involving a serine proteinase c

8 8 silencing by RNA interference inhibits pro-phenoloxidase activation and melanization of bacteria in

9 AUC studies and phenoloxidase activation measurements conducted with the

10 e Toll pathway, yet the comparative study of phenoloxidase activation reveals a differential activity

11 actions, for instance phagocytic capacity or phenoloxidase activation, or at the upstream signaling p

12 es, morphology on corn meal agar, urease and phenoloxidase activities, and carbohydrate assimilation

13 Conversely, cellular phenoloxidase activity (present in cell-lysates), demons

14 s between haemocyte count, antibacterial and phenoloxidase activity and resistance to S. marcescens i

15 had previously been demonstrated to exhibit phenoloxidase activity and was implicated in intrinsic c

16 Phenoloxidase activity capable of synthesizing melanin f

17 s, 1,8-diaminonapthalene, was used to detect phenoloxidase activity in gels after SDS-PAGE.

18 lencing of LvLGBP impaired the activation of phenoloxidase activity in shrimp by rLvHSP70, indicating

19 inding of LvHSP70 to LvLGBP highly activated phenoloxidase activity in shrimp hemocyte lysate superna

20 The inhibition of hemocyanin-derived phenoloxidase activity is discussed, and for the first t

21 Addition of autoactivated HP14 elevated phenoloxidase activity level in the larval plasma.

22 e circulating hemocytes and higher levels of phenoloxidase activity than the other strains upon infec

23 Ookinete melanization and hemolymph phenoloxidase activity were further increased after cosi

24 and immune response (number of hemocytes and phenoloxidase activity) of the nonbiting midge, Chironom

25 might also be costly and pleiotropic (e.g., phenoloxidase activity), posing challenges for further i

26 Cryptocyanin has no phenoloxidase activity, although a phenoloxidase is pres

27 und to have in vitro growth characteristics, phenoloxidase activity, and capsule size similar to thos

28 aemocyte count, implant encapsulation, total phenoloxidase activity, antibacterial zone of inhibition

29 e then measured endogenous immune responses (phenoloxidase activity, haemocyte concentration and mela

30 TBT affected all measured parameters, except phenoloxidase activity, when compared to the control.

31 cal functionalities, most notably, inducible phenoloxidase activity.

32 rg(51) but yielded a product that has little phenoloxidase activity.

33 rage increased the browning reactions due to phenoloxidase activity.

34 positive and nitrate negative and exhibited phenoloxidase activity.

35 Copper addition also stimulated both the phenoloxidase and ferroxidase activities of the enzyme,

36 expressed enzyme was demonstrated to exhibit phenoloxidase and ferroxidase activities.

37 Likewise, canonical immune effectors (phenoloxidase and lysozyme) showed similar patterns of e

38 ize, gonad size, and immune response through phenoloxidase and lytic activity.

39 antioxidant enzyme levels were modified, and phenoloxidase and total hemocyte count were decreased si

40 cyanin gene family-hemocyanin, cryptocyanin, phenoloxidase, and hexamerins-may participate in two vit

41 action of insects requires activation of pro-phenoloxidase by a proteolytic cascade leading to melani

42 mmune responses, including activation of the phenoloxidase cascade leading to melanization, nodule fo

43 gloverin, not previously associated with the phenoloxidase cascade.

44 effects of Pr1 and the reaction products of phenoloxidase caused larvae challenged with the engineer

45 ibitor concentration directly at the site of phenoloxidase contact.

46 o monitor the specific enzymatic activity of phenoloxidases during enzyme purification.

47 the most sensitive stains commonly used for phenoloxidases, e.g., 3,3-diaminobenzidine, and was clos

48 nes, and they cause significant reduction in phenoloxidase enzyme activity and delay in the melanizat

49 is) in shellfish has long been attributed to phenoloxidase enzymes.

50 dicating that these proteins may function as phenoloxidases in isopods, we discuss a possible role fo

51 Interestingly, a phenoloxidase inhibitor transcript increased 12-fold, ap

52 eractions of shellfish hemocyanin with known phenoloxidase inhibitors are presented.

53 quantified for female cellular immunity, and phenoloxidase, involved in melanization, and antibacteri

54 in has no phenoloxidase activity, although a phenoloxidase is present in the hemolymph.

55 Two kinds of phenoloxidases, laccase and tyrosinase, have been propos

56 significantly increased hemocyte counts and phenoloxidase levels in a dose-dependent manner (P < 0.0

57 s interact to produce synergistic effects on phenoloxidase (PO) activity and haemocyte count, both in

58 ore, we found that rPmLGBP could enhance the phenoloxidase (PO) activity of hemocyte suspensions in t

59 The hemolymph phenoloxidase (PO) activity of WSSV-infected shrimp was

60 des sigillatus, by comparing lytic activity, phenoloxidase (PO) activity, and encapsulation ability o

61 These two processes are mediated by phenoloxidase (PO) and Spatzle (Spz) through an extracel

62 Proteolytic activation of phenoloxidase (PO) and the cytokine Spatzle during immun

63 The phenoloxidase (PO) cascade regulates the melanization of

64 oduces a protein, Egf1.0, which inhibits the phenoloxidase (PO) cascade.

65 Arthropod phenoloxidase (PO) generates quinones and other toxic co

66 Phenoloxidase (PO) is believed to be a key mediator of i

67 Survival was monitored and the phenoloxidase (PO) response and bacterial load at 24-hr

68 density and pre-immune challenge activity of phenoloxidase (PO)) were significantly higher in selecti

69 tion is a potent immune response mediated by phenoloxidase (PO).

70 atterns of expression in both species, (with phenoloxidase remaining unchanged and lysozyme increasin

71 f trypsin-inhibitory activity, decreased the phenoloxidase response to LPS in a concentration-depende

72 ster hemocyte lysate leads to an increase in phenoloxidase response to LPS.

73 ity, Egf1.0 also prevented processing of pro-phenoloxidase, serine proteinase homolog (SPH) 1, and SP

74 as several advantages over other widely used phenoloxidase stains in that it is inexpensive, and the

75 blems of the type associated with many other phenoloxidase stains.

76 dsRNA-mediated transcript depletion for all phenoloxidases tested, with the exception of laccase 2.

77 ly by inhibiting the protease that activates phenoloxidase, the key enzyme in melanin synthesis.

78 sufficient for potent inhibition (low nM) of phenoloxidases, the enzymes responsible for producing me

79 ce of two serine proteinase homologs, active phenoloxidase was generated at a much higher level, and

80 The activity of the enzyme phenoloxidase, which initiates melanin biosynthesis, dra

81 accompanied by proteolytic activation of the phenoloxidase zymogen that is present in the hemolymph.