ライフサイエンスコーパス: phenylalanine

1 way leading to the synthesis of tyrosine and phenylalanine.

2 o acids were below normal levels, except for phenylalanine.

3 ed on the delta(15)N values of glutamate and phenylalanine.

4 ully prevented the procognitive effects of d-phenylalanine.

5 177 for valine, 199 for methionine, 186 for phenylalanine, 118 for leucine, and 89 for alanine.

6 tified (853 cm(-1) - proteins, 1209 cm(-1) - phenylalanine, 1265 cm(-1) - proteins, 1335 cm(-1) - pro

7 ectively, for 3,4-dihydroxy-6-(18)F-fluoro-l-phenylalanine ((18)F-FDOPA); and 100% and 70%-88%, respe

8 Using 3,4-dihydroxy-6-[(18)F]-fluoro-l-phenylalanine ([(18)F]-DOPA) positron emission tomograph

9 We also showed that replacing the phenylalanine 3.33 in CCR5 TM3 by the corresponding hist

10 Deletion of phenylalanine 508 (F508del) in the cystic fibrosis trans

11 In cystic fibrosis, deletion of phenylalanine 508 (F508del) in the cystic fibrosis trans

12 e of cystic fibrosis (CF) is the deletion of phenylalanine 508 (F508del) in the first nucleotide-bind

13 potential utility of HDACi in correcting the phenylalanine 508 deletion (F508del) CFTR variant as wel

14 ragine (5987.5microg/kg) and the lowest from phenylalanine (9.25microg/kg).

15 d-phenylalanine, a CA activator, displayed an opposite act

16 w that peptides incorporating the amino acid phenylalanine, a functional group that is conspicuously

17 Lower levels of phenylalanine, acetylhistidine, and cyclic adenosine mon

18 ther with other hydrophobic amino acids, the phenylalanines act as the channel's gate.

19 ter amended with tetrapeptide alanine-valine-phenylalanine-alanine (AVFA), a fragment of RuBisCO.

20 al compounds (proline, cysteine, tryptophan, phenylalanine, alpha-terpineol and geraniol).

21 The assay detects the release of phenylalanine amino acid in a reaction with the yeast en

22 Isoflavonoid compositions, phenylalanine ammonia lyase (PAL) activity and antioxida

23 hylene production, respiration, weight loss, phenylalanine ammonia lyase (PAL) activity and ion leaka

24 H2O2 accumulation was concurrent with higher phenylalanine ammonia lyase (PAL) enzyme activity leadin

25 ynthetic and therapeutic relevance, five new phenylalanine ammonia lyase (PAL) enzymes were discovere

26 tic activity of polyphenol oxidase (PPO) and phenylalanine ammonia lyase (PAL).

27 acid in a reaction with the yeast enzyme of phenylalanine ammonia lyase (PAL).

28 le for the ubiquitination and degradation of phenylalanine ammonia lyase (PAL).

29 eroxide dismutase), LOX (lipoxygenase), PAL (phenylalanine ammonia lyase), and PR-1 (pathogenesis rel

30 gher anthocyanin concentration due to higher phenylalanine ammonia-lyase (PAL) and lower polyphenol o

31 pruning triggered a transient expression of phenylalanine ammonia-lyase (PAL) and stilbene synthase

32 B46, encoding a transcriptional activator of PHENYLALANINE AMMONIA-LYASE (PAL) genes which are requir

33 Phenylalanine ammonia-lyase (PAL) is the first enzyme of

34 eatment induced significant decreases in the phenylalanine ammonia-lyase activity and significantly i

35 that initiate the degradation of the enzyme phenylalanine ammonia-lyase, which catalyzes the first s

36 peroxide dismutase, ascorbate peroxidase and phenylalanine ammonia-lyase.

37 sis studies supported the importance of this phenylalanine and confirmed the essential residues used

38 trial with a primed, constant infusion of D8-phenylalanine and D2-tyrosine.

39 is predominantly monomeric in the absence of phenylalanine and dimerizes in its presence, similar to

40 in highly disordered repeats of hydrophobic phenylalanine and glycine intermingled with charged amin

41 with regards to blood orange juice, and for phenylalanine and glycine, with regards to orange juice.

42 primed, continuous infusions of L-[ring-2H5]phenylalanine and ingested either 31 g (26.2 g protein:

43 , or 45 (45 g PRO) g intrinsically l-[1-13C]-phenylalanine and l-[1-13C]-leucine labeled milk protein

44 Two of these were identified as L-phenylalanine and L-tyrosine but it may be that metaboli

45 89)Ala-Ser-Gly(191) residues and the bound l-phenylalanine and l-tyrosine, conferring the deamination

46 y of one-pot DSL-deselenization chemistry at phenylalanine and leucine was demonstrated through the r

47 Feeding pigs with LP + BCAA impacted the phenylalanine and protein metabolism and fatty acids syn

48 of Capsicum fruits with Actium(R) increased phenylalanine and total monosaccharides (glucose and fru

49 (alanine and lactate), and disease severity (phenylalanine and tryptophan metabolites).

50 y, levels of the neurotransmitter precursors phenylalanine and tryptophan were decreased.

51 of taurine, isoglutamine, choline, lactate, phenylalanine and tyrosine and decreased levels of lipid

52 pathway, is required for the biosynthesis of phenylalanine and tyrosine in bacteria, archaea, plants,

53 showed alterations in lysine degradation and phenylalanine and tyrosine metabolism.

54 s analyzed for amino acid concentrations and phenylalanine and tyrosine tracer enrichments from which

55 All three aromatic amino acids (tryptophan, phenylalanine and tyrosine) serve as substrates for the

56 ion not only for aspartic acid, but also for phenylalanine and tyrosine, inconsistent with racemizati

57 na benthamiana starting from the amino acids phenylalanine and tyrosine.

58 ct amino acid oxidation (DAAO; with l-[1-13C]phenylalanine) and indicator amino acid oxidation (IAAO;

59 ucine), aromatic amino acids (tryptophan and phenylalanine), and glycerophospholipids (phosphatidylch

60 cardic acids, sucrose, malic acid, tyrosine, phenylalanine, and important flavor compounds (esters, a

61 nched-chain amino acids, tryptophan pathway, phenylalanine, and lipoproteins, pointing to mitochondri

62 e (PAH) is a key enzyme in the catabolism of phenylalanine, and mutations in this enzyme cause phenyl

63 23% higher after SG (both P < .05); the peak phenylalanine appearance rate from ingested casein was 1

64 Plasma leucine concentrations and exogenous phenylalanine appearance rates increased after protein i

65 in ~70%-74% of the ingested protein-derived phenylalanine appearing in the circulation.

66 he sialyltransferase, rST6Gal1, in which all phenylalanines are labeled with (15)N, and the results a

67 ed N-formyl peptide, formyl-methionyl-leucyl-phenylalanine, are elevated in high-fat diet-induced obe

68 ining a conserved motif in which amino acids Phenylalanine-Arginine-Tryptophan (FRW) predominate coul

69 ive photoelectrochemical biosensor towards L-phenylalanine, as a kind of typical essential amino acid

70 e presence of highly conserved tryptophan or phenylalanine at position 182.

71 to correct p.Phe508del mutation (the loss of phenylalanine at position 508) and increase the amount o

72 For both WT- and DeltaF508 (deletion of phenylalanine at position 508, the most common CF-causin

73 Plasma exogenous phenylalanine availability over the 5-h postprandial per

74 rporate the photoactive amino acid p-azido-l-phenylalanine (azF) into N-terminal residues of a full-l

75 uce the unnatural amino acid (UAA) p-azido-l-phenylalanine (azF) into the intracellular loops (ICLs)

76 -benzoyl-l-phenylalanine (BzF) and p-azido-l-phenylalanine (AzF).

77 S also reveal several isotopic shifts of the phenylalanine band, of which the positions correlate wel

78 received primed continuous l-[ring-(2) H(5) ]phenylalanine before consuming a mixed meal.

79 tes based on 4 chemically diverse scaffolds (phenylalanine, benzoic acid, heteroaromatic, and aliphat

80 anthin, indoline carboxylic acid-betacyanin, phenylalanine-betaxanthin, and dopaxanthin, behaved as e

81 was active only inside nodules, whereas the phenylalanine bioreporter showed a high signal also in t

82 a microbial-like phenylpyruvate pathway for phenylalanine biosynthesis in plants.

83 the dilution effect of different pathways of phenylalanine biosynthesis in Pseudomonas sp.

84 Thus, our results complete elucidation of phenylalanine biosynthesis via phenylpyruvate in plants,

85 increased enzymatic breakdown of sugars and phenylalanine biosynthesis.

86 TePhe labeling is competitive with phenylalanine but not other large and aromatic amino aci

87 o acid (UAA) photocross-linkers, p-benzoyl-l-phenylalanine (BzF) and p-azido-l-phenylalanine (AzF).

88 CAR-T cells and changing this asparagine to phenylalanine (CD28-YMFM) promoted durable antitumor con

89 d in MDCK cells in the presence of N-tosyl-l-phenylalanine chloromethyl ketone-treated trypsin.

90 s floral volatiles derived sequentially from phenylalanine, cinnamic acid, and p-coumaric acid.

91 f polypeptide clamp sites: an alpha clamp, a phenylalanine clamp, and a charge clamp.

92 ne residues in the alpha-dbn C terminus with phenylalanine compromising the alphakap-alpha-dbn intera

93 over 10 y was inversely associated with the phenylalanine concentration in men (P = 0.007) but not i

94 The serum phenylalanine concentration is associated with telomere

95 No intervention is required if the blood phenylalanine concentration is less than 360 mumol/L.

96 inverse association was observed between the phenylalanine concentration that was measured 5 y earlie

97 alue and correlated with pre-treatment blood phenylalanine concentrations (n = 6,115) and tetrahydrob

98 ous symptoms associated with high biological phenylalanine concentrations that occur with the genetic

99 peptide correspond to leucine, tyrosine and phenylalanine containing domains being this interaction

100 ion of individual tryptophan-, tyrosine- and phenylalanine-containing dipeptides, 50-80% of the total

101 the microbial porA gene facilitates dietary phenylalanine conversion into phenylacetic acid, with su

102 Enriched phenylalanine, cysteine-HCl and high lysine:arginine rat

103 acid sequence arginine-glycine-aspartic acid-phenylalanine-cysteine (RGDFC) attached.

104 Phenylalanine-d(8) was selected as the single PCI-IS to

105 ived oxazolidinones would be superior to the phenylalanine-derived analogues.

106 In contrast to the phenylalanine-derived anthocyanins, betalains are tyrosi

107 (Tyr) and replaced the otherwise ubiquitous phenylalanine-derived anthocyanins.

108 Our results support a role for phenylalanine-derived small molecules in preformed and i

109 a one-pot Knoevenagel-IMDA reaction of an l-phenylalanine-derived tetramic acid and (R)-2-methyl-dec

110 A reduction in phenylalanine deuteration in Pseudomonas sp. compared to

111 peptidase activities that cleave the proline-phenylalanine dipeptide bond in Ang II.

112 sults suggest a higher requirement (40%) for phenylalanine during late pregnancy than during early pr

113 Currently, dietary requirements for phenylalanine during pregnancy are unknown.

114 the Phe43 cavity, where residue 43 of CD4 (a phenylalanine) engages with gp120.

115 rine atom introduced in the para-position of phenylalanine enhanced the binding affinity as much as 1

116 ryptophan was replaced with a non-oxidizable phenylalanine exhibited higher catalase activity and les

117 Spontaneously, phenylalanine (F) molecules coordinate with zinc ions to

118 While its phosphodeficient phenylalanine (F) mutant activated both transcription an

119 The E2 phenylalanine (F) mutant Y138F displayed reduced FGFR3-i

120 proximal C26 H* donor (including Y224) with phenylalanine (F) revealed that only the Y68F variant (i

121 ing those containing an amidated arginine(R)-phenylalanine(F) motif at their C-termini (RFamide pepti

122 directly to proteins containing a FFAT [two phenylalanines (FF) in an acidic tract (AT)] motif.

123 oteins dysfunction may contribute to reduced phenylalanine flux without affecting insulin resistance

124 oteins dysfunction may contribute to reduced phenylalanine flux without affecting insulin resistance

125 ficantly increased N-formyl-methionyl-leucyl phenylalanine (fMLF)-stimulated superoxide release to an

126 d absence of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) (1 muM) stimulation.

127 mulated with N-Formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) and after pretreatment of the cells

128 ry chemoattractant N--formylmethionyl-leucyl-phenylalanine (fMLP) is mediated by leukotriene B4 (LTB4

129 sed in response to N-formyl-methionyl-leucyl-phenylalanine (fMLP) stimulation.

130 d also reduces the N-formyl-methionyl-leucyl-phenylalanine (fMLP)-induced neutrophil respiratory burs

131 The kinetics of N-formylmethionyl-leucyl-phenylalanine (fMLP)-mediated neutrophil migration was s

132 covered by a ring of 5 arginines, whereas 5 phenylalanines form a hydrophobic barrier in its exit.

133 Mutation of the TM2.6 residue of TREK-1 to a phenylalanine (G171F) and a similar mutation of TM4.6 (A

134 emistry to act as an effective latch for the phenylalanine gate.

135 Rather, amino acids alanine, phenylalanine, glutamic acid, valine, and leucine increa

136 cetylcholine and decreased concentrations of phenylalanine, glutamine, isoleucine, leucine and glycer

137 atively unfolded polypeptides, which contain phenylalanine-glycine (FG) binding sites for nuclear tra

138 ols the passage of molecules via hydrophobic phenylalanine-glycine (FG) domains on nucleoporins.

139 disordered proteins that contain hydrophobic phenylalanine-glycine (FG) motifs, known as FG nucleopor

140 t protein sequestration, nor blockade of the phenylalanine-glycine (FG)-rich nuclear pore complex.

141 One-third of these Nups contain phenylalanine-glycine (FG)-rich repeats, forming a diffu

142 y disordered regions (IDRs) from a family of phenylalanine-glycine-rich nucleoporins (FG-Nups) to con

143 uit of NPCs is highly enriched in disordered phenylalanine/glycine-rich nucleoporins (FG-Nups), which

144 ly-dipeptide binds to polymeric forms of the phenylalanine:glycine (FG) repeat domain, which is share

145 Gene sequencing revealed a phenylalanine-->isoleucine mutation in the 33rd position

146 399), in endogenous PTPROt was replaced with phenylalanine had increased bone mass and reduced osteoc

147 Tyrosine and phenylalanine had positive correlations with their DPPH

148 Human phenylalanine hydroxylase (hPAH) hydroxylates L-phenylal

149 Dysfunction of human phenylalanine hydroxylase (hPAH, EC 1.14.16.1) is the pr

150 ylketonuria (PKU), caused by variants in the phenylalanine hydroxylase (PAH) gene, is the most common

151 Phenylalanine hydroxylase (PAH) is a key enzyme in the c

152 th HPA harbor mutations in the gene encoding phenylalanine hydroxylase (PAH), and a small proportion

153 The naturally occurring R68S substitution of phenylalanine hydroxylase (PheH) causes phenylketonuria

154 Phenylketonuria (PKU, phenylalanine hydroxylase deficiency), an inborn error o

155 They share a glycine-phenylalanine-hydroxyproline/alanine (GFO/A) motif that

156 hich a tryptophan residue is substituted for phenylalanine in an activation loop to explore the role

157 Phenylalanine in NF tumors was found to be elevated in b

158 sine residue, which required the exchange of phenylalanine in PDP-Nal to tyrosine in order to disrupt

159 ncrease in the concentration of fumarate and phenylalanine in stored salmon muscle.

160 domain, which binds a motif named FFAT (two phenylalanines in an acidic tract).

161 ertain AA (eg: Taurine, glutamine, tyrosine, phenylalanine) in the driest treatment (-10 MPa) were si

162 ation, we designed point-mutants (alanine to phenylalanine) in the predicted, tightly packed TM domai

163 tive in the absence of allosteric binding of phenylalanine, in contrast to the WT enzyme.

164 e substitution of leucine at position 752 to phenylalanine, in PLAA, which causes disruption of the p

165 e compounds inhibit N-formylmethionyl-leucyl-phenylalanine induced spreading of human neutrophils as

166 ere evaluated by using intravenous [ring-2H5]phenylalanine infusion in conjunction with muscle biopsi

167 -d period to determine the acute (via [13C6]-phenylalanine infusion) and longer-term (ingestion of de

168 e assessed by primed continuous l-[ring-13C6]phenylalanine infusions with the collection of blood sam

169 The degradation of phenylalanine initiated by 2-pentenal, 2,4-heptadienal,

170 ation to the At5g63620 locus, resulting in a phenylalanine instead of serine on position 223.

171 1 y, mean +/- SD) were studied at a range of phenylalanine intakes (5.5-30.5 mg . kg-1 . d-1 in early

172 DAAO method was appropriate even though low phenylalanine intakes could not be tested.

173 senting the mean requirement) in response to phenylalanine intakes.

174 -bonded radical cation due to the methionine-phenylalanine interaction, which is consistent with a sm

175 nylalanine mutants suggest that LLPS-driving phenylalanine interactions are significantly weaker than

176 oration of dietary protein-derived l-[1-13C]-phenylalanine into de novo mitochondrial protein increas

177 s catalyzing the BH4-activated conversion of phenylalanine into tyrosine, tyrosine into L-dopa (the p

178 eactive, non-natural amino acid, p-benzoyl-l-phenylalanine, into various positions of the structurall

179 tion to being a vital component of proteins, phenylalanine is also a precursor of numerous aromatic p

180 Phenylalanine is an indispensable amino acid and, via ty

181 In plants phenylalanine is synthesized predominantly via the aroge

182 SF(5)Phe, para-pentafluorosulfanyl phenylalanine, is an unnatural amino acid with extreme p

183 tides containing Lys and either DOPA (KY) or phenylalanine (KF) shows that DOPA is stronger and more

184 21, 10.04 +/- 0.30, and 13.49 +/- 0.55 mumol phenylalanine . kg-1 . h-1, respectively; P < 0.001).

185 Phenylalanine kinetics were reduced in the haemodialysis

186 on (<2min) and accurate quantifications of L-phenylalanine (L-Phe) in plasma and whole-blood newborns

187 nylalanine hydroxylase (hPAH) hydroxylates L-phenylalanine (L-Phe) to L-tyrosine, a precursor for neu

188 a primed continuous infusion of l-[ring-2H5]-phenylalanine, l-[ring-3,5-2H2]-tyrosine, and l-[1-13C]-

189 The potential of three amino acids (l-phenylalanine, l-tyrosine, l-tryptophan) and a polypepti

190 that enhances dopamine function (dihydroxy-L-phenylalanine; L-DOPA) reduces the impact of valence on

191 containing labeled glucose and intrinsically phenylalanine-labeled caseinate.

192 Cysteine, histidine, phenylalanine, lysine, tryptophan and arginine were the

193 c acid-[cyclo(arginyl-glycyl-aspartic acid-D-phenylalanine-lysine)], both in several tissue types and

194 sociated with perturbation of tryptophan and phenylalanine metabolism (BH(4) cycle), glycerophospholi

195 Phenylalanine metabolism was determined using two-compar

196 ingolipid metabolism, tryptophan metabolism, phenylalanine metabolism, lysine biosynthesis and degrad

197 Domain III allows binding of the isoleucine-phenylalanine-methionine (IFM) motif to the inactivation

198 demonstrating its molecular specificity as a phenylalanine mimic; labeling is also abrogated in vitro

199 ectable HPV-31 genomes with phosphodeficient phenylalanine mutant E2 Y138F and phosphomimetic glutami

200 because experiments on FtoA and tyrosine-to-phenylalanine mutants suggest that LLPS-driving phenylal

201 a mouse strain with a homologous cysteine to phenylalanine mutation (C105F) in the UMOD gene was gene

202 Substitution of Asn(255) with phenylalanine (N255F), together with substitution of Trp

203 neurotransmitter in learning and memory) and phenylalanine (neurotransmitter precursor) after alpha-H

204 Commercially available 4-iodo-phenylalanine or 4-iodobenzyl bromide served as the star

205 Feeding experiments with deuterated phenylalanine or deuterated (E/Z)-PAOx showed that (E/Z)

206 ring the reaction between alpha-amino acids (phenylalanine or methionine) and either gallic acid, caf

207 ddition, plasma tyrosine-but not methionine, phenylalanine, or succinylacetone-increased in homozygou

208 IL-4-induced gene-1 (IL4I1), a secreted l-phenylalanine oxidase expressed by APCs, has been detect

209 yielding higher urea excretion and increased phenylalanine oxidation rates (P < 0.01).

210 on circulating and 24 h urinary excretion of phenylalanine (PA), tyrosine (TYR), hydroxyphenylpyruvat

211 The tyrosine and phenylalanine pathways were unaltered under both conditi

212 The large hydrophobic amino acid p-benzoyl phenylalanine (pBzF) was substituted for Tyr72, which le

213 eplacing tyrosine 48 with p-carboxy-methyl-l-phenylalanine (pCMF).

214 ation of methyl jasmonate (MeJ) supported by phenylalanine (Phe) as a precursor feeding (MeJ+Phe) and

215 hyperaccumulation of the aromatic amino acid phenylalanine (Phe) in animals, known as phenylketonuria

216 Vine foliar applications of phenylalanine (Phe) or methyl jasmonate (MeJ) could impr

217 M2 activity, but addition of the inhibitor L-phenylalanine (Phe) prevents maximal activation of FBP-b

218 In Mfn1 and Mfn2 paralogs, a conserved phenylalanine (Phe-202 (Mfn1) and Phe-223 (Mfn2)) locate

219 for a series of mutations at a second sphere phenylalanine positioned in proximity to the bound subst

220 Whereas d-phenylalanine potentiated extinction, acetazolamide impa

221 Phenylalanine, precursor of several volatile and phenoli

222 In this work, we show that the amino acid phenylalanine produces increased membrane permeability,

223 oxyl radicals can oxidize the phenyl ring of phenylalanine, producing the abnormal tyrosine isomer me

224 for directing carbon flux towards cytosolic phenylalanine production via the phenylpyruvate pathway.

225 mutant, in which tyrosine 729 was mutated to phenylalanine, promoted monocyte rather than neutrophil

226 Phenylalanine rates of appearance and disappearance, as

227 Phenylalanine replacement of either of these residues de

228 Phenylalanine requirement during early pregnancy was det

229 Phenylalanine requirement was determined using a 2-phase

230 This study's aim was to determine phenylalanine requirements (in the presence of excess ty

231 Specifically, a phenylalanine residue (GcoA-F169) interferes with the bi

232 Our results indicate that the elimination of phenylalanine residue 211 or 213 abolishes the UQ-depend

233 l-CFTR (where F508del is the deletion of the phenylalanine residue at position 508) at the plasma mem

234 The conserved phenylalanine residue F329 closing the transport pore of

235 ectively, confirmed the accessibility of the phenylalanine residue for antibody recognition.

236 dy characterized that a missense mutation on phenylalanine residue located in CRD2 (TNFR1(F60V) ) cau

237 from an ammonium salt incorporating d- or l-phenylalanine residues as chiral stereogenic covalent un

238 d more extensive pai-CH interactions between phenylalanine residues forming the roof of the active-si

239 nes are positively charged and interact with phenylalanine residues in a hydrophobic cleft between ad

240 /trans-isomerase B following mutation of two phenylalanine residues in the core of the protein to SF(

241 rane-facing leucine, isoleucine, valine, and phenylalanine residues in the transmembrane alpha-helice

242 Two phenylalanine residues located adjacent to the substitut

243 Histidine, arginine, tyrosine, and phenylalanine residues preferentially take oxygen from H

244 In place of tyrosine or phenylalanine residues prototypically used for phase sep

245 A ring of phenylalanine residues repositions to expose previously

246 gical measurements to identify two conserved phenylalanine residues that form an aromatic pathway who

247 he ideal alpha-helical geometry due to three phenylalanine residues, which stack within each helix an

248 three critical and evolutionarily invariant phenylalanine residues.

249 on availability of cofactor ligands, BH4 and phenylalanine, respectively.

250 ssessed whether kisspeptin (Kp) and arginine-phenylalanine (RF)-amide related peptide-3 (RFRP-3), two

251 the protease through recognition of a short phenylalanine-rich motif, and the presence of similar mo

252 molecule binding site in the DNAJA1 glycine/phenylalanine-rich region.

253 ially positive gamma-methylene in mimicry of phenylalanine's quadrupolar interaction.

254 idation is necessary, however, especially of phenylalanine's role in condensate assembly because expe

255 n is a missense substitution of serine-34 to phenylalanine (S34F).

256 binding site polarity and that a tyrosine to phenylalanine substitution at a binding site could be de

257 2-KPCC differs from other DSORs by having a phenylalanine that replaces a conserved histidine, which

258 Two critical central phenylalanines that directly coordinate F(-) through a q

259 whereas replacement of C932 with leucine or phenylalanine, the latter of a size comparable to argini

260 Moreover, the content of phenylalanine, the precursor of flavonoids, was also red

261 e-specific incorporation of 4-trimethylsilyl phenylalanine (TMSiPhe) into proteins, through genetic c

262 e extracts from plumeria flowers converted l-phenylalanine to (E/Z)-PAOx, PAld, 2PE, BN, and PN.

263 A polymerase III holoenzyme by mutation of a phenylalanine to a SF(5)Phe residue, (ii) site-specifica

264 we make use of an azido group of a p-azido-l-phenylalanine to achieve chemical orthogonality.

265 e nonoxidative elimination of ammonia from l-phenylalanine to give trans-cinnamate.

266 The transition from phenylalanine to tyrosine differs only by the presence o

267 cific incorporation of a clickable p-azido-L-phenylalanine to Uox and strain-promoted azide-alkyne cy

268 ances via single-point mutations of selected phenylalanines to tyrosines.

269 a nonproteinogenic P1 residue (4-guanidyl-l-phenylalanine) to produce a potent (Ki = 1.6 nM) and the

270 data on the wild-type, a charge-scrambled, a phenylalanine-to-alanine (FtoA), and an arginine-to-lysi

271 n of Abeta(16-22) and how it is modulated by phenylalanine-to-cyclohexylalanine (CHA) mutations.

272 (PKU) is a rare genetic disorder that causes phenylalanine toxicity in the brain.

273 methionyl aminoacyl-tRNA synthetase), FARSB (phenylalanine-tRNA synthetase, beta-subunit), and NPC2 (

274 les by targeting proteins harboring leucine, phenylalanine, tryptophan, or tyrosine at the N terminus

275 Nine AAs (phenylalanine, tryptophan, tyrosine, alanine, isoleucine

276 sity RDA to EAA content ranged between 1.35 (phenylalanine + tyrosine) and 3.68 (leucine), with a mea

277 late protein is a good source of tryptophan, phenylalanine + tyrosine, isoleucine, histidine, but lim

278 A repair and combination, purine metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, rib

279 serine, proline, asparagine, aspartic acid, phenylalanine, tyrosine, and histidine levels compared w

280 Mutants with phenylalanine, tyrosine, and methionine substitutions we

281 -chaperone family member that interacts with phenylalanine, tyrosine, and tryptophan hydroxylases cat

282 of amino acids (arginine, histidine, lysine, phenylalanine, tyrosine, and tryptophan) makes it a viab

283 lanine, valine, leucine, methionine, lysine, phenylalanine, tyrosine, and tryptophan.

284 ons of stable isotopes of glucose, glycerol, phenylalanine, tyrosine, and urea before and during a mi

285 re composed of arginine, leucine/isoleucine, phenylalanine, tyrosine, valine and proline significantl

286 ne, lysine, isoleucine, leucine, methionine, phenylalanine, valine, GABA, glutamine, alanine, glycine

287 conditions have seduced the self-reaction of phenylalanine via [2 + 2 + 2] cycloaddition and minimize

288 The concentration of phenylalanine was constantly increased during the storag

289 pon stimulation with formyl-methionyl-leucyl phenylalanine was found to identify sputum eosinophilia

290 ffects were observed when acetazolamide or d-phenylalanine was infused locally into the substantia ni

291 al, isotopically labeled p-((13)C(15)N-cyano)phenylalanine was synthesized, site-selectively incorpor

292 ilitate radical-induced side-chain damage in phenylalanine, was found for the reaction of NO(3)(*) wi

293 R1 activation with N-formyl-methionyl-leucyl phenylalanine, WDR26 dissociates from FPR1, resulting in

294 dation products of tryptophan, tyrosine, and phenylalanine were detected.

295 smonates, phenylpropanoids, terpenoids and L-phenylalanine were most strongly upregulated.

296 ne(973) in the juxtamembrane region of IR to phenylalanine, which is present in IGF1R, mimics many of

297 from delta (15)N values of glutamic acid and phenylalanine, which range from 8.3-33.1 per thousand an

298 primed continuous infusion of l-[ring-13C6]-phenylalanine with serial muscle biopsies was used to de

299 Y102E) or to the nonphosphorylated homologue phenylalanine (Y102F) remain nuclear; however, Y102E is

300 , chemotaxis receptor, vimentin, fibrin, and phenylalanine zippers that vary in size and topology of