ライフサイエンスコーパス: phenylalanyl-tRNA

1 tes diacetyl-[14C]lysyl-tRNA and acetyl-[14C]phenylalanyl-tRNA.

2 The leucyl/phenylalanyl-tRNA-protein transferase (L/F-transferase)

3 ize aminoacyl-tRNA recognition by the leucyl/phenylalanyl-tRNA-protein transferase (L/Ftransferase).

4 ares 45% identity with the yeast cytoplasmic phenylalanyl tRNA synthetase (PheRS) regulatory alpha-su

5 ug resistance was engineered using a mutated phenylalanyl tRNA synthetase gene and marking strains wi

6 ion from fars-3, an essential subunit of the phenylalanyl tRNA synthetase.

7 Inhibition of purified yeast phenylalanyl-tRNA synthetase (FRS) catalyzed aminoacylat

8 ficity in AcKRS and in a PylRS variant [iodo-phenylalanyl-tRNA synthetase (IFRS)] that displays both

9 Human mitochondrial phenylalanyl-tRNA synthetase (mtPheRS) has been identifi

10 the amino acid binding and recognition step, phenylalanyl-tRNA synthetase (PheRS) faces the challenge

11 Phenylalanyl-tRNA synthetase (PheRS) is a multidomain (a

12 Phenylalanyl-tRNA synthetase (PheRS) maintains specifici

13 Phenylalanyl-tRNA synthetase (PheRS) preferentially liga

14 For example phenylalanyl-tRNA synthetase (PheRS) proofreads the non-

15 olutionary divergence of tyrosine editing by phenylalanyl-tRNA synthetase (PheRS) was used as a model

16 n its acceptor stem that prevents editing by phenylalanyl-tRNA synthetase (PheRS), leading to the acc

17 translation by the proofreading activity of phenylalanyl-tRNA synthetase (PheRS).

18 that of the heterotetrameric (alphabeta)(2) phenylalanyl-tRNA synthetase (PheRS).

19 ies of binding of phenylalanine analogues to phenylalanyl-tRNA synthetase (PheRS).

20 molog of one subunit of prokaryote and yeast phenylalanyl-tRNA synthetase (PheRS).

21 ynthetase (PylRS) is structurally related to phenylalanyl-tRNA synthetase (PheRS).

22 A designed yeast phenylalanyl-tRNA synthetase (yPheRS (T415G)) activates

23 or tRNA (ytRNA(Phe)(CUA)) and a mutant yeast phenylalanyl-tRNA synthetase (yPheRS (T415G)) into an Es

24 -acetyllysyl-tRNA synthetase [AcKRS], 3-iodo-phenylalanyl-tRNA synthetase [IFRS], a broad specific Py

25 and the aminoacyl-tRNA hydrolytic domain of phenylalanyl-tRNA synthetase are functionally and evolut

26 we have engineered a Caenorhabditis elegans phenylalanyl-tRNA synthetase capable of tagging proteins

27 e we report that wild-type E. coli EF-Tu and phenylalanyl-tRNA synthetase collaborate with these muta

28 c azetidines targeting Plasmodium falciparum phenylalanyl-tRNA synthetase comprise one promising new

29 The phenylalanyl-tRNA synthetase editing mechanism is also a

30 crimination in vivo revealed that editing by phenylalanyl-tRNA synthetase is essential for faithful t

31 We show that phenylalanyl-tRNA synthetase misactivates tyrosine and t

32 computationally designed mutant form of the phenylalanyl-tRNA synthetase of the host.

33 The phenylalanyl-tRNA synthetase variants S57C and N280S bot

34 To define the mechanism of editing, phenylalanyl-tRNA synthetase was used to investigate dif

35 nthesized in nature (by Thermus thermophilus phenylalanyl-tRNA synthetase), and many disubstituted tR

36 n of the nucleus-encoded human mitochondrial phenylalanyl-tRNA synthetase, which aminoacylates hmt-tR

37 from the active site of human mitochondrial phenylalanyl-tRNA synthetase.

38 lanyl-tRNA is formed by Thermus thermophilus phenylalanyl-tRNA synthetase.

39 lyclonal antibodies raised against mammalian phenylalanyl-tRNA synthetase.

40 ines that inhibit a new antimalarial target, phenylalanyl-tRNA synthetase.

41 a proofreading ("editing") activity, such as phenylalanyl-tRNA synthetases (PheRS) that hydrolyze mis

42 tivity of aminoacyl-tRNA synthetases such as phenylalanyl-tRNA synthetases (PheRS), which edit misact

43 In addition, seryl- and phenylalanyl-tRNA synthetases that are only marginally r

44 erminal module that resembles the OB-fold of phenylalanyl-tRNA synthetases.