ライフサイエンスコーパス: phenylthio

1 xyandro-stenedione (4-OHA), 7alpha-(4'-amino)phenylthio-1, 4-androstandiene-3,17-dione (7alpha-APTADD

2 oxyandrostenedione (4-OHA), 7alpha-(4'-amino)phenylthio-1,4-androstandiene-3,17-dione (7alpha-APTADD)

3 [4-hydroxyandrostenedione, 7alpha-(4'-amino)phenylthio-1,4-androstandiene-3,17-dione, and bridge (2,

4 hat the selective Epac activator 8-(4-chloro-phenylthio)-2'-O-methyladenosine-3', 5-cyclic monophosph

5 cific cAMP analog 8CPT-2Me-cAMP (8-(4-chloro-phenylthio)-2'-O-methyladenosine-3',5'-cAMP) activates R

6 8-(4-chloro-phenylthio)-2'-O-methyladenosine-3'-5'-cyclic monophosph

7 8-(4-Chloro-phenylthio)-2-O-methyladenosine-3'-5'-cyclic monophospha

8 , N, N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)-5-bromobenzylamine (36), and N, N-dimethyl-2

9 : N, N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)-5-fluorobenzylamine (35), N, N-dimethyl-2-(2

10 d N, N-dimethyl-2-(2'-amino-4'-hydroxymethyl-phenylthio)-5-iodobenzylamine (37).

11 Under these conditions, 6-phenylthio-5,6,7,8-tetrahydronaphthalenes are formed dia

12 sis of all four stereoisomers of 5-hydroxy-6-phenylthio-5,6-dihydrothymidine (T*), which, upon 254 nm

13 esis of 2,4,6-trisubstituted pyridines from (phenylthio)acetic acid and a range of alpha,beta-unsatur

14 radical decarboxylation of alpha-alkoxy beta-phenylthio acids via the corresponding Barton esters.

15 The phenylthio acids were usually made by the known regiosel

16 reactions of imines and enamines with alpha-phenylthio, alpha-phenylsulfonyl, and alpha-diethylphosp

17 N-amidinyliminium ion generated from alpha-(phenylthio)amidine precursor 16 by reaction with Cu(OTf)

18 On the other hand, phenylthio and phenylsulfonyl entities were successfully

19 (2'-((dimethylamino)methyl)-4'-(fluoroalkoxy)phenylthio)benzenamine (4'-2-fluoroethoxy derivatives 28

20 Tris(phenylthio)benzene molecules have been synthesized in or

21 th (11)C-3-amino-4-(2-[(dimethylamino)methyl]phenylthio)benzonitrile ((11)C-DASB).

22 thly with the crypt[2.1.1] complex of alpha-(phenylthio)benzyllithium as the initiator and enolate as

23 mpatibility with 8 types of sugar along with phenylthio/benzylseleno esters.

24 126 (1,4-diamino-2,3-dicyano-1,4-bis[2-amino-phenylthio]butadiene) blocked ERK phosphorylation, and a

25 126 (1,4-diamino-2,3-dicyano-1,4-bis[2-amino-phenylthio]butadiene), demonstrating that signaling path

26 the histone deacetylase inhibitor methyl-4-(phenylthio)butanoate, which we subsequently administered

27 Here, we found that 4-(phenylthio)butanoic acid (PTBA) expanded the expression

28 The most powerful inhibitor was 5'-p-Cl-phenylthio-DADMe-Immucillin-A (pClPhT-DADMe-ImmA) with a

29 p-Cl-phenylthio-DADMe-immucillin-A binds with a dissociation

30 he 5'-position at the catalytic site with 5'-phenylthio-DADMe-immucillin-A gave a dissociation consta

31 ser-flash photolysis of the corresponding N-(phenylthio) derivatives, and the rate constants for the

32 The ring contraction reaction of methoxy- or phenylthio-diazepinones under acidic conditions resulted

33 gioselective synthesis of phenoxy esters and phenylthio esters is reported.

34 l]-1H-imidazole and 4-[2-(3-(trifluoromethyl)phenylthio)ethyl]-1H-imidazole are shown to be partial a

35 The use of a phenylthio group (SPh) as a dummy ligand at the 6-positi

36 titution of the methylthio group with a p-Cl-phenylthio group gives a more powerful inhibitor with a

37 itution of the 5'-methylthio group with a 5'-phenylthio group gives an equilibrium binding constant o

38 in-3-ones motifs has been developed from C-3 phenylthio indoles.

39 y chiral selenophosphoramides afforded alpha-phenylthio ketones in generally high yield and with good

40 e d-mannose, through a highly functionalized phenylthio mannoside, the l-gulose donor was prepared by

41 The substituted (phenylthio)methane boronate was converted to the corresp

42 lowed to react with the stabilized anion of (phenylthio)methane boronate, PhSCH(2)BO(2)C(6)H(12), to

43 (10), and four nonclassical 2,4-diamino-5-((phenylthio)methyl)pyrrolo[2,3-d]pyrimidines with 3',4'-d

44 tion-conjugate addition reaction to form 1-[(phenylthio)methyl]-5-[(ethoxycarbonyl)methyl]-6-acetamid

45 In contrast, the synthesis of 3-[(phenylthio)methyl]cyclohex-2-en-1-one (6) and 3-(1,3-dit

46 Although 4-(phenylthio)-N-(4-phenyl-2-oxobutyl)azetidin-2-one, SB-21

47 is the S homologue 4-[3-(3-(trifluoromethyl)phenylthio)propyl]-1H-imidazole and its CH(2) isostere 4

48 These 2,5'-thiodipyrimidine and 5-(phenylthio)pyrimidine acrylamides take advantage of an a

49 ,5'-cyclic monophosphorothioate, 8-(4-chloro-phenylthio) (R(p)-8-pCPT-cGMPs), or DT-2 blocked the ant

50 ese donors showed higher reactivity than the phenylthio sialosides and could be activated by NIS/TfOH

51 es of 2-(phenylamino), 2-(phenyloxy), and 2-(phenylthio) substitutions, the order of affinity at the