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1 ts SRC basal activation independently of its phosphatase activity.
2 ose production despite the loss of glucose-6-phosphatase activity.
3 membrane and nucleus without affecting lipid phosphatase activity.
4 calcium release on its way to activation of phosphatase activity.
5 ssed by staining for tartrate-resistant acid phosphatase activity.
6 human Treg cells and provides complementary phosphatase activity.
7 tion of purified PP2Ac with CIN85 suppressed phosphatase activity.
8 ons leads to significant or complete loss of phosphatase activity.
9 SUMOylated, yet is independent of its lipid phosphatase activity.
10 dependent platelet function by dampening the phosphatase activity.
11 f LC20 upon inhibition of myosin light chain phosphatase activity.
12 or and OC protein addition enhanced alkaline phosphatase activity.
13 e effect associated with intestinal alkaline phosphatase activity.
14 , which occurs independently of antagonizing phosphatase activity.
15 r factor-kappaB ligand (RANKL), and alkaline phosphatase activity.
16 ated PTEN mutations block its essential PIP3 phosphatase activity.
17 nd B subunits were stable and uncoupled from phosphatase activity.
18 ad deficient mineral apposition and alkaline phosphatase activity.
19 Asn394 as a critical amino acid involved in phosphatase activity.
20 e that help decipher the mechanism of glucan phosphatase activity.
21 phosphorylation of Shp2, which inhibits Shp2 phosphatase activity.
22 idative stress response through its NADPH 2' phosphatase activity.
23 ed ligands and inhibits its protein-tyrosine phosphatase activity.
24 brane electrical potential to inositol lipid phosphatase activity.
25 y with Ssu72 and strongly stimulates its CTD phosphatase activity.
26 ins and is concurrent with increases in PTEN phosphatase activity.
27 roximately 5-fold increase in Cps2B-mediated phosphatase activity.
28 nsport, PSRP1-sRNPC is stable against phloem phosphatase activity.
29 mplex and reduces but does not fully abolish phosphatase activity.
30 sociated with significant reduction in local phosphatase activity.
31 ase activity must be counteracted by protein phosphatase activity.
32 means for modulating the balance of CDK and phosphatase activity.
33 id kinase activity and stimulates Fig4 lipid phosphatase activity.
34 in the stimulation (6-fold) of phosphatidate phosphatase activity.
35 ensor domain that is expected to control the phosphatase activity.
36 XNWD motif, results in maximal activation of phosphatase activity.
37 chondrial membranes, which is independent of phosphatase activity.
38 and CnPpz1 in vitro but do not inhibit their phosphatase activity.
39 2) levels on endosomes, independently of its phosphatase activity.
40 adherin internalization independently of its phosphatase activity.
41 ain and membrane-targeting motif can restore phosphatase activity.
42 tiates TGF-beta signaling independent of its phosphatase activity.
43 LSF1 complex shows amylolytic but not glucan phosphatase activity.
44 atase (DSP) domain of LSF1 had no detectable phosphatase activity.
45 duced type 1 collagen secretion and alkaline phosphatase activity.
46 ority of them stained intensely for alkaline phosphatase activity.
47 iptional coactivators with intrinsic protein phosphatase activity.
48 ction networks depends on protein kinase and phosphatase activities.
49 SIK2-PP2A complex preserves both kinase and phosphatase activities.
50 se activity or both PTEN's lipid and protein phosphatase activities.
51 e loss of PTEN protein phosphatase and lipid phosphatase activities.
52 PTEN has mainly been attributed to its lipid phosphatase activity, a role for PTEN protein phosphatas
55 8(MAPK) determines signal amplitude, whereas phosphatase activity affects both signal amplitude and d
56 genic related markers (osteopontin, alkaline phosphatase activity, Alizarin red, and Von Kossa) compa
57 /-), which is associated with an impaired 5'-phosphatase activity, also leads to Parkinson's disease
58 osphorylation of Synj at S1029 enhances Synj phosphatase activity, alters interaction between Synj an
59 tional model that combines MAPK scaffold and phosphatase activities and is sufficient to account for
60 on in ICL repair is dependent on its protein phosphatase activity and ability to be SUMOylated, yet i
62 e found an inverse relationship between root phosphatase activity and AM colonization in field-collec
65 esulting in significantly increased alkaline phosphatase activity and calcium deposition of encapsula
67 ntration of cytoplasmic free zinc, increased phosphatase activity and decreased phosphorylation of si
68 cleaved by calpain-2, which inactivates its phosphatase activity and generates stable breakdown prod
69 terfaces, we show that D2 inhibits RPTPalpha phosphatase activity and identified a (405)PFTP(408) mot
70 R306, of EYA1 are essential for its in vitro phosphatase activity and in vivo function during Drosoph
71 nstrate that PTPN1 mutations lead to reduced phosphatase activity and increased phosphorylation of JA
72 d in partial inhibition of its ATP-dependent phosphatase activity and inhibited subsequent phosphoryl
73 9R-mutant endometrial cancer cells increases phosphatase activity and inhibits tumor growth in vivo F
74 al rearrangement reversal is correlated with phosphatase activity and is influenced by the membrane's
75 on of Pah1 stimulated both its phosphatidate phosphatase activity and its subsequent phosphorylation
77 P-activated signaling pathway controls SHP-1 phosphatase activity and may regulate numerous receptor
78 r, the p85alpha homodimer enhances the lipid phosphatase activity and membrane association of PTEN.
79 rotein levels and induced increased alkaline phosphatase activity and mineralization in osteoblast cu
81 competition, however, AM colonization, root phosphatase activity and N2 fixation increased in the N2
82 formance remain unclear: biomass allocation, phosphatase activity and phosphorus-use efficiency did n
83 d on gamma glutamyl transferase and alkaline phosphatase activity and proliferative responses to secr
84 de-phosphorylation of PTEN, increased lipid-phosphatase activity and reduced Akt kinase activity in
85 show that FTY720-P enhances TNF-induced PP2A phosphatase activity and significantly represses TNF-ind
86 nt in polyP coincided with enhanced alkaline phosphatase activity and substitution of sulfolipids for
88 phate and tensin homolog through its protein phosphatase activity and that the increase in INPP4B is
89 acute pharmacological inhibition of the Eya2 phosphatase activity and the DNA damage checkpoint kinas
90 mains of Pah1 are required for phosphatidate phosphatase activity and the in vivo function of the enz
91 tion based on the maintenance of the Ser/Thr phosphatase activity and their neuroprotection against t
92 only tyrosine phosphatase activity, has dual phosphatase activities, and both the N- and C-terminal d
93 d and van Kossa stain and increased alkaline phosphatase activity, and by increased expression of ost
94 ulation of organic acids, enhanced secretory phosphatase activity, and depletion of ATP in overexpres
95 ant effects on protein synthesis or alkaline phosphatase activity, and drove discrete changes in a pa
96 disrupted sebocyte cell membranes, alkaline phosphatase activity, and significantly reduced sebocyte
97 ponent analysis shows that dehydrogenase and phosphatase activities are the vital variables contribut
98 tection from proteolysis, and stimulation of phosphatase activity are linked to oligomerization of Sp
101 we report inherited dysregulation of protein phosphatase activity as a cause of intellectual disabili
102 EN protein has lipid phosphatase and protein phosphatase activity, as well as other functions in the
104 9D) constructs, in vitro binding assays, and phosphatase activity assays, we demonstrate that phospho
106 PHLPP phosphatase network allows coordinated phosphatase activities at the site of T-cell receptor ac
108 ive estimates for the intracellular alkaline phosphatase activity at five different temperatures in d
110 ssion of OsHAD1 in rice resulted in enhanced phosphatase activity, biomass, and total and soluble P c
111 s no change in glycogen content or glucose 6-phosphatase activity but increased Slc2a2 glucose transp
112 of ethanol, caused no changes in BP or RVLM phosphatase activity but it produced significant increas
113 usually is attributed to myosin light chain phosphatase activity, but findings in non-VSM identified
115 ing (<=5 years) significantly increased soil phosphatase activity by 28%, long-term N loading had no
118 c homology 2 domain-containing phosphatase 2 phosphatase activity by scavenging reactive oxygen speci
119 burgdorferi CheD significantly enhances CheX phosphatase activity by specifically interacting with th
122 greatly promote MSC proliferation, alkaline phosphatase activity, calcium deposition and total prote
123 ent with this finding, inhibition of STRIPAK phosphatase activity causes cell morphology defects in m
124 BL) and enhanced the respiratory burst, acid phosphatase activity, chemotactic activity, and gene exp
126 inhibiting kinase activity while stimulating phosphatase activity, consistent with the selective inac
129 pects of disease pathology, with reduced DNA phosphatase activity correlating with neurodevelopmental
131 sponse to TNF, and this increased GADD34-PP1 phosphatase activity, dephosphorylating eukaryotic trans
134 or of STAT5 through liberation of endogenous phosphatase activity following NADPH oxidase (NOX) inhib
135 itant with a significant increase in protein phosphatase activity for two colon cancer cell lines in
138 tes, including bile acids transfer, alkaline phosphatase activity, gamma-glutamyl-transpeptidase acti
139 the N2 fixer with high N2 fixation and root phosphatase activity grew best on organic P, whereas the
140 , a GAS strain selectively deficient in CovS phosphatase activity had a distinct transcriptome relati
141 nd temporal regulation of protein kinase and phosphatase activities has to be achieved in the cell to
143 hich has been reported to have only tyrosine phosphatase activity, has dual phosphatase activities, a
144 we manipulated native loci to ablate hCDC14A phosphatase activity (hCDC14A(PD)) in untransformed hTER
145 Unexpectedly, we observed that inhibiting a phosphatase activity highly sensitive to OA caused an ab
146 he coronavirus macrodomain has ADP-ribose-1"-phosphatase activity; however, its function during infec
148 Chlamydomonas GPD2 showed both reductase and phosphatase activities in vitro and it can work as a bif
149 merize with wild-type PTEN and constrain its phosphatase activity in a dominant-negative manner.
151 hosphatase activity, a role for PTEN protein phosphatase activity in cell cycle regulation has also b
153 orylation in its activation and PTEN protein phosphatase activity in governing glycolysis and tumorig
154 Cs in the lesion cap, and increased alkaline phosphatase activity in lesions in the Ahr knockout in c
157 ion of OC protein partially rescued alkaline phosphatase activity in periodontal ligament (PDL) cells
158 cant increases in BP and inhibition of local phosphatase activity in rats treated with OKA or fostrie
159 ly members, serving as a platform to control phosphatase activity in response to diverse inputs.
160 Under laboratory conditions, BvgS shifts to phosphatase activity in response to modulators, notably
161 ate, showing that BvgS shifts from kinase to phosphatase activity in response to this modulator via a
163 tion uncover a novel mechanism whereby lipid phosphatase activity in the nucleus can regulate mammali
165 5Thr mutation in SHP-1 caused a reduction in phosphatase activity in vitro, confirming the loss-of-fu
166 ed on the inhibition of immobilized alkaline phosphatase activity, in the presence of the phosphate i
167 ulate actin cytoskeleton dynamics and myosin phosphatase activity, including focal adhesion kinase, p
171 strain, indicating that both CovS kinase and phosphatase activities influence the CovR phosphorylatio
172 al RNA-binding NSP2 octamer with nucleotidyl phosphatase activity is central to viroplasm formation a
173 esults indicate that scaffolding of inositol phosphatase activity is critical for maintaining PtdIns(
176 is study, we demonstrate that PTEN's protein phosphatase activity is required for epiblast epithelial
177 nd maintain 1 null allele, we show that PTEN phosphatase activity is required for preventing the emer
179 ab7, a recently identified substrate of PTEN phosphatase activity, is also a substrate of the innate
180 omplement lsf1 Thus, glucan binding, but not phosphatase activity, is required for the function of LS
181 h in vivo and in vitro, loss of EYA tyrosine phosphatase activity leads to defective assembly of gamm
184 well-investigated, little is known about its phosphatase activity, located in the N-terminal phosphat
185 confounders, such as inflammation, alkaline phosphatase activity, low serum albumin, renal function,
186 hanced differentiation indicated by alkaline phosphatase activity, mineral deposition, and transcript
187 entiation as indicated by increased alkaline phosphatase activity, mineralization, and up-regulation
189 These results indicate that neither Cps2B phosphatase activity nor Cps2D phosphorylation levels pe
190 concentrations shift the relative kinase and phosphatase activities of diphosphoinositol pentakisphos
191 ies of the bifunctional 5-InsP7 kinase/InsP8 phosphatase activities of full-length diphosphoinositol
192 ctively requires both the DNA kinase and DNA phosphatase activities of PNKP, and the fork-head associ
195 ere, we identified tumor inhibitory and RelA phosphatase activities of the protein phosphatase 2C (PP
196 , we show that the nuclease, polymerase, and phosphatase activities of yeast CPF are organized into t
197 stabilize beta-catenin while increasing the phosphatase activity of a Ppp2r2c-containing Pp2a comple
198 nteraction with AtMIA40 is necessary for the phosphatase activity of AtSLP2 and is dependent on the f
199 at dimerization is important for controlling phosphatase activity of CacyBP/SIP and for regulating th
203 with our previous results that the tyrosine phosphatase activity of Eya is dispensable for normal Ey
204 86Ser) transgenic mice demonstrates that the phosphatase activity of FIG4 has an essential role in vi
205 ed model has been postulated to regulate the phosphatase activity of HisKA HKs based on the pH-depend
209 ular allosteric regulation mechanism for the phosphatase activity of PGAM5, in which the assembly of
212 ever, Hsp70 binding to PP5 stimulates higher phosphatase activity of PP5 than the binding of Hsp90.
215 PTEN mutant constructs, we show that protein phosphatase activity of PTEN targets PTK6, with efficien
216 tumors, functionally caused the loss of the phosphatase activity of PTPRD, and were associated with
217 vels increased mRNA, protein expression, and phosphatase activity of SHP-1, which remained elevated d
223 oadly conserved mechanism that regulates the phosphatase activity of the largest family of bifunction
228 ith PTEN mutants that lack only PTEN's lipid phosphatase activity or both PTEN's lipid and protein ph
229 enopus early embryonic extract revealed that phosphatase activity other than PP1 continuously suppres
230 table catalytic His with phosphotransfer and phosphatase activities over an effector response regulat
231 15 (P = 0.0001), and calcification (alkaline phosphatase activity, P < 0.01; osteocalcin, P < 0.05).
232 ere, we use fission yeast to investigate how phosphatase activity participates in this interplay duri
233 GAS mutants lacking SP-PTP revealed that the phosphatase activity per se positively regulates growth,
235 acdc55 mutation affecting Cdc55-PP2A protein phosphatase activity prevented Orm dephosphorylation and
236 sion of a mutated form of PTEN with enhanced phosphatase activity prevented the TGF-beta-induced coll
238 arterial hypertension and that EYA3 tyrosine phosphatase activity promotes the survival of these cell
239 1 directly binds to STRIPAK and inhibits its phosphatase activity, protecting MST2 activation-loop ph
240 fferences we observed in voltage-sensing and phosphatase activity provide a starting point for future
242 Fig4 mutations predicted to inactivate FIG4 phosphatase activity rescue lysosome expansion phenotype
243 tracellular stores and increased calcineurin phosphatase activity, resulting in NFATc1 nuclear transl
247 rmacological inhibition of the EYA3 tyrosine phosphatase activity substantially reverses vascular rem
248 weight, long bone length, and serum alkaline phosphatase activity, suggesting that tooth dysfunction
250 dystrophies to defective phosphoinositide 5-phosphatase activity that is becoming increasingly recog
253 a novel positive regulator of lipin 1beta PA phosphatase activity that is not achieved via altering i
254 use a significant reduction in phosphatidate phosphatase activity, the phosphorylation of Pah1p by pr
255 rovascular integrity by enabling VEC-related phosphatase activity, thereby preventing vascular leak d
256 e receptor kinase activity or enhancing CheC phosphatase activity, thereby regulating the levels of t
257 term through the initial stimulation of soil phosphatase activity, thereby securing P supply to suppo
258 revealed activation of PKA and inhibition of phosphatase activity thus explaining the increase in pho
259 antly, S-nitrosylation of PTEN decreases its phosphatase activity, thus promoting cell survival.
260 pair factor possessing both 5'-kinase and 3'-phosphatase activities to modify ends of a DNA break pri
261 iring holoenzyme formation and reducing PP2A phosphatase activity to promote endometrial cancer progr
268 addition, we find key differences in glucan phosphatase activity toward soluble and insoluble polygl
272 high basal autophagy, possess stronger basal phosphatase activity towards ULK1 and require ULK1 for s
273 ation, starvation also causes an increase in phosphatase activity towards ULK1, an mTORC1 substrate w
274 genesis, the additional loss of PTEN protein-phosphatase activity triggered an extensive cell death r
276 cherichia coli similarly exhibited increased phosphatase activity under conditions of high-oxygen gro
277 m substrate trapping complexes with impaired phosphatase activity via increased recruitment of TIPRL1
282 elate with phosphorus associations; however, phosphatase activity was most strongly down-regulated in
283 vitro and in vivo data demonstrated that the phosphatase activity was required for the inactivation o
285 uced Smad 1/5/8 phosphorylation and alkaline phosphatase activity were both enhanced by the addition
286 A on cell proliferation, migration, and PP2A phosphatase activity were investigated using ovarian and
287 genes, among which genes involved in protein phosphatase activity were overrepresented, suggesting a
288 te that Hsp70 recruits PP5 and activates its phosphatase activity which suggests dual roles for PP5 t
289 is governed by dynamic changes in kinase and phosphatase activities, which are difficult to assess wi
291 ressor activity depends largely on its lipid phosphatase activity, which opposes PI3K/AKT activation.
292 tion with CD45 on the T cell, inhibiting its phosphatase activity, which resulted in up-regulation of
293 atus of actin, as was its eIF2alpha-directed phosphatase activity, while localised G-actin depletion
294 d osteoblast differentiation marker alkaline phosphatase activity, while miR-138 inhibitor and OC pro
296 tations in these allosteric clusters altered phosphatase activity with changes in kcat/KM ranging fro
297 oint mutations in cps2B demonstrated reduced phosphatase activity with corresponding increases in lev
298 n and septum formation and FgCdc14 possesses phosphatase activity with specificity for a subset of Cd