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1 onors such as acetyl phosphate and carbamoyl phosphate.
2 protein that binds to phosphatidylinositol 3-phosphate.
3 alkyl-phosphonate moiety replacing the gamma-phosphate.
4 cleaves adenosine into adenine and ribose-1-phosphate.
5 oduce the prosurvival molecule sphingosine-1-phosphate.
6 ing media to permit precipitation of calcium phosphate.
7 o dihydroxyacetone phosphate and erythrose 4-phosphate.
8 plemental diet rich in calcium, lactose, and phosphate.
9 mpatible ceramic nanoparticles of tricalcium phosphate.
10 ibited by its substrate RuBP and other sugar phosphates.
11 ndicate the coexistence of linear and cyclic phosphates.
14 t signaling pathways, phosphatidylinositol 5-phosphate 4-kinases (PI5P4Ks) are attractive targets for
15 a member of the rice phosphatidylinositol-4-phosphate 5-kinase family, as a protein that interacts w
16 strate that type Igamma phosphatidylinositol phosphate 5-kinase i5 (PIPKIgammai5), an endosome-locali
17 d adults with COVID-19 receiving chloroquine phosphate, 500 mg once or twice daily, with patients not
18 te homeostasis (PHO) regulon comprises three phosphate acquisition genes - pho1, pho84, and tgp1 - th
21 Micro-Tom'; the wild type and the GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE [GPAT6] and CUTIN SYNTHASE [CU
22 E)/PPE clusters, responsive to magnesium and phosphate, also showed a phthiocerol dimycocerosate-depe
23 ctive site entailing dislocations of the ATP phosphates, altered contacts to ATP, and variations in t
24 verexpression of Gfat1 (glutamine:fructose-6-phosphate amidotransferase 1), the rate-limiting enzyme
25 we report the design of a series of inositol phosphate analogs as crystallization inhibitors, among w
26 o sub-micromolar concentrations of inorganic phosphate and a range of environmentally abundant P form
27 rticles, and low HDL levels of sphingosine-1-phosphate and apolipoprotein A-I were associated with in
30 ences in Raman features corresponding to the phosphate and carbonate bands between the benign and mal
32 ation of Ca phosphates between NaOH-desorbed phosphate and exchangeable Ca(2+) and/or (2) dissolution
33 cantly lower percent tubular reabsorption of phosphate and fibroblast growth factor-23 (FGF23) at all
34 expression of mGPDH, which lowers glycerol 3-phosphate and G6P and also mimics the G6pc repression by
36 id environments (pH <= 5), particularly when phosphate and other competitors are present in relativel
38 cal method for the determination of citrate, phosphate and sulfite in seafood by capillary zone elect
40 ron spectroscopy (XPS) confirmed the role of phosphates and carboxylate groups from the cell envelope
43 e presence of close analogs (i.e., glucose-6-phosphate), and can detect glucose above a threshold con
44 hate, pyruvate, lactate, alanine, glycerol-3 phosphate, and isocitrate were significantly associated
46 ies, including radioligand binding, inositol phosphate, and toxicity assays, proved that we have a se
47 The stable isotopes of sulfate, nitrate, and phosphate are frequently used to study geobiological pro
48 of triphenylphosphine selenide and diphenyl phosphate as a catalyst, a wide range of unsaturated ami
51 es showed a remarkably high concentration of phosphates at the bacterial cell wall compared to other
54 signaling, with phosphatidylinositol (PI) 3-phosphates being the predominant phosphoinositide lipids
55 NaOH), creating new Ca-P via formation of Ca phosphates between NaOH-desorbed phosphate and exchangea
56 ndings do not support the role of intestinal phosphate binders to reduce cardiovascular risk in patie
57 he ubiquity of phospho-ligands suggests that phosphate binding emerged at the earliest stage of prote
59 milarities in their overall architecture and phosphate binding motif, a lack of sequence identity and
60 logical P(i)-receptor based on the bacterial phosphate binding protein with the principle of thermoph
62 s and unravel its details, we identified all phosphate-binding protein lineages in the Evolutionary C
64 ent in several enzymes that hydrolyze cyclic phosphate bonds on different substrates, including cycli
65 load-bearing skeleton and bioglass-magnesium phosphate bone cement as the osteoconductive matrix.
66 t CSH C18 column with gradient elution using phosphate buffer and methanol was used for their optimal
67 inetics of murine norovirus (MNV) by PFA, in phosphate buffer and municipal secondary effluent wastew
69 eved from FAU (SiO(2):Al(2)O(3) = 80:1) into phosphate buffer for 24 h followed by prolonged release
71 n black particle suspension solution (pH 7.0 phosphate buffer) at varying carbon black concentrations
72 y in the simulated river water samples as in phosphate buffer, reflecting its applicability to real s
73 entrations of Immunoglobulin G (IgG) in both phosphate buffered saline (PBS) and spiked in E. coli ce
74 in a complex matrix (bovine serum albumin in phosphate buffered saline) is also demonstrated through
76 ignificant reduction of diarrhea compared to phosphate-buffered saline (PBS) controls (PE = 84.1%; P
77 Four groups were studied: sham and SCI plus phosphate-buffered saline (SCI + PBS), human embryonic k
78 iae (1,500 colony-forming units) or vehicle (phosphate-buffered saline) at 3 or 60 days post-injury.
83 acquisition or result in overaccumulation of phosphate by S. aureus However, it does reduce the abili
87 concentration depends on the beta-glucose 1-phosphate concentration, couples the conformational swit
90 es, prebiotic experiments commonly use molar phosphate concentrations to overcome phosphate's poor re
92 onium-boronate hydrogen bonds, which enables phosphate coordination to boron with a concomitant, ster
93 ced microstructural phase changes of calcium phosphate (CP) leading to the formation of brushite, mon
95 n, calcium is frequently bound to the Pb(II) phosphate crystal lattice structure, causing measurable
97 ular calcification, the formation of calcium phosphate crystals in the vessel wall, is mediated by va
101 Moreover, higher activities of glucose 6-phosphate dehydrogenase (G6PDH), 6-phosphogluconate dehy
103 esin-1, gelsolin, tubulins, glyceraldehyde-3-phosphate dehydrogenase, calmodulin, ATP synthase, sperm
104 sh L-lactate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, pyruvate kinase, and glucose-6-
106 hine aminotransferase (hOAT), a pyridoxal 5'-phosphate-dependent enzyme, plays a critical role in the
107 ect, presumably because they generate ribose-phosphate derivatives from products of an unlinked but e
111 vities of carbonic anhydrase (CA), pyruvate, phosphate dikinase (PPDK), ribulose-1,5-bisphosphate car
113 as expected, but also unexpectedly increased phosphate efflux, whereas PFBC-associated SLC20A2 varian
115 somerize fructose-6-phosphate into glucose-6-phosphate even in the presence of equimolar amounts of g
121 disease suggests that they jointly regulate phosphate fluxes and cellular homeostasis, but direct ev
122 atients with and without IBD evaluated serum phosphate for 28 days following intravenous FCM, and ass
123 were chosen for aggregating AgNPs, potassium phosphate for neutralizing the charges and a di-thiol mo
124 er P through FeOOH absorption and authigenic phosphate formation in sediments, and accordingly reduce
127 the Escherichia coli periplasmic glycerol-3-phosphate (G3P)-binding protein UgpB can serve, in the a
128 (hGGT1) with glutathione (a substrate) and a phosphate-glutathione analog (an irreversible inhibitor)
129 in kinases (EPKs) catalyze the transfer of a phosphate group onto another protein in response to appr
130 etermined that both the bromine atom and the phosphate group were successfully substituted by means o
131 nd in soft source conditions, the protonated phosphate groups are fully back-exchanged in the source,
132 dictated by the number and positions of the phosphate groups in the inositol ring (with seven differ
133 the contribution of the different inositide phosphate groups to catalysis, these structures provide
134 m intercept to identify significant Cytosine-phosphate-Guanine (CpG) sites and differentially methyla
135 ng this period at asthma-associated cytosine-phosphate-guanine (CpG) sites and such an association wa
136 with altered DNA methylation at 605 cytosine-phosphate-guanine (CpG) sites, which were associated wit
137 4 and rs2299007 risk alleles create cytosine-phosphate-guanine sites, which are highly methylated and
138 only demethylation of histones and cytosine-phosphate-guanines (CpGs) in gene promoters and other re
139 , 2-methyl-4-amino-5-hydroxymethylpyrimidine phosphate (HMP-P), has been described to proceed through
141 ross-talk between SLC20A2 and XPR1 regulates phosphate homeostasis, and we identified XPR1 as a key i
142 operon encoding a highly conserved inorganic phosphate importer, PstSCAB, increases the sensitivity o
145 ould be categorized similarly to nitrate and phosphate in that it originates in part from fertilizer
147 ples, we found substantial amounts of cyclic phosphates in X. autotrophicus, suggesting that in fresh
148 bited complexes while binding multiple sugar phosphates, including its substrate ribulose 1,5-bisphos
149 dulates the expression of a large set of low-phosphate-induced genes that respond to local and system
152 erum protein fetuin-A stabilizes calcium and phosphate into 70-100 nm-sized colloidal calciprotein pa
154 tion, hGFAT2 is able to isomerize fructose-6-phosphate into glucose-6-phosphate even in the presence
156 ; however, leaf entry pathways for inorganic phosphate ion (Pi) uptake remain unknown, and it is uncl
157 at the speciation and transport behaviors of phosphate ions are highly influenced by electrolyte pH,
160 (the TriPPPro approach), in which the gamma-phosphate is covalently modified by two different biodeg
163 deficiency of the glycolytic enzyme glucose phosphate isomerase (Gpi1) selectively eliminates inflam
165 xin-5, secretoglobin family 1D and glucose-6-phosphate isomerase characterized the LF phenotype.
166 onserved with close similarity to the triose-phosphate isomerase protein sequence from Dermatophagoid
167 ehydrogenase, pyruvate kinase, and glucose-6-phosphate isomerase showed IgE-binding for 6%-13% of pat
168 signaling axis comprising phosphoinositide 3-phosphate kinase, Akt Ser/Thr kinase, nitric oxide synth
170 urinary phosphate excretion maintains serum phosphate levels within the normal range, thus protectin
171 dings, we create functional Li||lithium iron phosphate (LFP) batteries in which LFP cathodes with hig
173 include the expansion of genes for inorganic phosphate metabolism, the presence of genes for producti
175 ke homo-hexacontamer, we conclude that while phosphate moieties present in crRNA and ATP molecules en
176 tions of Hoogsten hydrogen bonds, sugar, and phosphate moieties to the specific G-vacancy fill-in.
178 y the glassy structure as primarily isolated phosphate monomers with N incorporated in both apical an
179 ) or the steroid group (topical prednisolone phosphate; n = 57); both regimens were tapered over 10 w
181 thyleneglycol)-myo-inositol-1,2,3,5-tetrakis(phosphate), (OEG(2))(2)-IP4, displays increased in vitro
182 te (cPyPA) reagent is used to introduce four phosphates on nucleosides regioselectively in a one-flas
183 counteracted by the presence of preadsorbed phosphate or by increasing the BSA coverage, which preve
184 ot prevent the level decrease in high-energy phosphates or protein constituents of mitochondrial resp
185 SD), 0.33; 95% CI, 0.18-0.61), sphingosine-1-phosphate (OR(1SD): 0.60; 95% CI: 0.40-0.89), and apolip
186 s and that nicotinamide adenine dinucleotide phosphate oxidase (NOX)-dependent ROS production might b
187 takes of total energy (p < 0.001), inorganic phosphate (p < 0.001), and phosphate:protein ratio (p =
188 rotein (p = 0.001), and animal-based organic phosphate (p < 0.001), whilst T3-SSB(dp) patients had si
192 ous Pb compounds (i.e., carbonate, chloride, phosphate [P], or sulfate) to convert native Pb species
196 Survival upon nutrient stress or pentose phosphate pathway (PPP) inhibition depends on compensato
197 glycolysis but increased use of the pentose phosphate pathway (PPP), and an enhanced abundance of th
198 hat may regulate serum urate via the pentose-phosphate pathway and MRPS7 and IDH2 that encode protein
199 d the Krebs cycle, but the levels of pentose phosphate pathway metabolites and of many free amino aci
200 IspH, an enzyme in the methyl erythritol phosphate pathway of isoprenoid synthesis, is essential
201 ssociated cystine metabolism and the pentose phosphate pathway, and uncover an accompanying metabolic
202 ased flux through glycolysis and the pentose phosphate pathway, thereby establishing a critical link
204 With high initial ratio of calcium ion to phosphate, periodic precipitation was obtained accompani
211 icular, cholesterol and phosphatidylinositol phosphate (PIP) lipids, but the number, location, and es
214 ate, vitamin B-6 in the form of pyridoxal 5'-phosphate (PLP), and total B-12 with serum TC, LDL-C, HD
215 in LpThi5 is a dimer that binds pyridoxal-5'-phosphate (PLP), apparently without a solvent-exposed Sc
221 luated and describe two new series of cyclic phosphate prodrugs of PPA capable of regenerating excell
223 Simultaneous activation of carboxylates and phosphates provides multiple pathways for the generation
224 hrough stimulation of phosphatidylinositol-3-phosphate (PtdIns(3)P) production and ER membrane curvat
226 formed dentine comprises equal carbonate to phosphate ratios and mineral to matrix ratios to that of
229 le sclerosis, is an agonist of sphingosine-1-phosphate receptor (S1PR), which has been used as a rese
231 emokine receptor 7 (CCR7) and sphingosine 1- phosphate receptor-1 (S1PR1) expression and glucose meta
232 RORc and an antagonist of the sphingosine-1-phosphate receptor-1-via late-stage methylation from the
233 te, suggesting cation-independent, mannose 6-phosphate receptor-mediated endocytosis from the cell su
234 show that retinal endothelial sphingosine 1-phosphate receptors (S1PRs), which restrain vascular end
235 cence, and nicotinamide adenine dinucleotide phosphate, reduced form oxidases (NOXs) were studied in
236 gs suggest that aging of branch junctions by phosphate release from Arp2/3 complex and mechanical for
237 nes by coupling ATP binding, hydrolysis, and phosphate release to translocation of diverse substrates
239 utrient recovery, but their effectiveness on phosphate removal was lower than other charged ions.
241 , pho84, and tgp1 - that are repressed under phosphate-replete conditions by 5' flanking lncRNAs prt,
244 regulator GNOM and its suppressor, ADENOSINE PHOSPHATE RIBOSYLATION FACTOR GTPase ACTIVATION PROTEIN
246 e molar phosphate concentrations to overcome phosphate's poor reactivity with organics in water.
250 ingolipid metabolites, such as sphingosine-1-phosphate (S1P), play important roles as second messenge
251 pendent cell proliferation and sphingosine-1-phosphate (S1P)-dependent entosis and apical cell extrus
253 rsible pathway, PFK converts sedoheptulose 7-phosphate (S7P) to SBP, after which fructose-bisphosphat
254 in sheep using 3D-printed customized calcium phosphate scaffolds with or without surgical vasculariza
255 Root system configuration in response to phosphate scarcity involved MED16 functioning, which mod
259 ually transformed into one containing a lead phosphate solid chemically similar to phosphohedyphane (
260 s after preparation of oversaturated calcium phosphate solutions, PNS with a hydrodynamic radius of R
263 l maximum encoded genes related to light and phosphate stress (psbA, psbD and pstS in T4-like and psb
264 ids at endosomes and lysosomes, whereas PI 4-phosphates, such as phosphatidylinositol 4,5-bisphosphat
265 can be competitively inhibited by mannose 6-phosphate, suggesting cation-independent, mannose 6-phos
266 aturally occurring minerals (e.g., silicate, phosphate, sulfate) follows energy-intensive chemical ro
267 Five "competing" co-occurring oxo-anions (phosphate, sulfate, bicarbonate, silicate, and nitrate)
268 Pb is shown to be associated with fatty acid phosphate, sulfate, chloride, and carboxylate ions.
269 al enzyme, 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAH7PS), at the gateway to aromatic
270 ite mutation in the 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS) gene, with minor contribution
272 on catalyzed by the enzyme indole-3-glycerol phosphate synthase (IGPS) starts with a condensation ste
273 ohol phosphotransferase phosphatidylinositol-phosphate synthase (PIPS), an essential enzyme for mycob
274 te pathway, 3-deoxy-d-arabinoheptulosonate 7-phosphate synthase and chorismate synthase, were also up
275 o up-regulated, as well as indole-3-glycerol phosphate synthase, an enzyme involved in the biosynthes
276 detect the enzyme, 5-enolpyruvulshikimate-3-phosphate synthase, from Agrobacterium sp. strain CP4 (C
277 bidopsis (Arabidopsis thaliana), TREHALOSE-6-PHOSPHATE SYNTHASE1 (TPS1) catalyzes the synthesis of th
281 ata support a model in which HPr transfers a phosphate to an unidentified downstream transcriptional
282 ase 1 (GFAT1), uses glutamine and fructose 6-phosphate to eventually synthesize uridine diphosphate N
284 ries of vinylated analogues of sphingosine-1-phosphate together with their unambiguous configurationa
285 We demonstrated that knockdown of XPR1, a phosphate transporter present in MIN6m9 cells and pancre
286 the sucrose-signaling metabolite trehalose 6-phosphate (Tre6P) and is essential for embryogenesis and
290 r PF-06869206 was previously shown to reduce phosphate uptake in human proximal tubular cells in vitr
292 that overexpression of WT SLC20A2 increased phosphate uptake, as expected, but also unexpectedly inc
293 st from this exudation in terms of increased phosphate uptake, suggesting that root structure plays a
296 ed at the end of the 12-week experiment, and phosphate was found to drive Zn speciation in both OW an
298 ve been defined, it is unknown if persistent phosphate wasting in nephropathic cystinosis is associat
299 ine/inorganic phosphate and NTP/exchangeable phosphate were higher at 48 h in HT+M versus HT (p = 0.0
300 ards normal, and (2) decreased intracellular phosphate, which down-regulated PRPP synthetase activity