ライフサイエンスコーパス: phosphatidate phosphatase

1 cascade that regulates the function of Pah1 phosphatidate phosphatase.

2 degradation was conserved for human lipin 1 phosphatidate phosphatase.

3 This was accompanied by a reduction in phosphatidate phosphatase 1 (PAP1) activity.

4 Saccharomyces cerevisiae membrane-associated phosphatidate phosphatase (3-sn-phosphatidate phosphohyd

5 was performed to determine the mechanism of phosphatidate phosphatase activation by anionic phosphol

6 biosynthesis of triacylglycerol through its phosphatidate phosphatase activity and also acts as a tr

7 positively charged sphingoid base, inhibited phosphatidate phosphatase activity and antagonized the a

8 Lipin proteins have phosphatidate phosphatase activity and catalyze the form

9 phosphorylation of Pah1 stimulated both its phosphatidate phosphatase activity and its subsequent ph

10 genase-like domains of Pah1 are required for phosphatidate phosphatase activity and the in vivo funct

11 ese results suggested that the activation of phosphatidate phosphatase activity by anionic phospholip

12 growth phase-mediated inductions of PAH1 and phosphatidate phosphatase activity do not correlate with

13 also abrogates the nuclear translocation and phosphatidate phosphatase activity of lipin-1.

14 Anionic phospholipids activated phosphatidate phosphatase activity whereas zwitterionic

15 se A, which cause a significant reduction in phosphatidate phosphatase activity, the phosphorylation

16 tase resulted in the stimulation (6-fold) of phosphatidate phosphatase activity.

17 f Pah1 regulate its subcellular location and phosphatidate phosphatase activity.

18 ane expansion, which occurs in cells lacking phosphatidate phosphatase activity.

19 nositol were mixed competitive activators of phosphatidate phosphatase activity.

20 Loss of phosphatidate phosphatase also resulted in the derepress

21 mation of diacylglycerol by the PAH1-encoded phosphatidate phosphatase and by channeling diacylglycer

22 is a protein phosphatase that activates Pah1 phosphatidate phosphatase at the nuclear-endoplasmic ret

23 PAH1-encoded phosphatidate phosphatase catalyzes the penultimate step

24 Pah1, a phosphatidate phosphatase catalyzing the dephosphorylati

25 his enzyme, in conjunction with PAH1-encoded phosphatidate phosphatase, controls the levels of phosph

26 neither a substrate nor an inhibitor of pure phosphatidate phosphatase from S. cerevisiae.

27 Lipin-1 is a phosphatidate phosphatase in glycerolipid biosynthesis a

28 Pah1 phosphatidate phosphatase in Saccharomyces cerevisiae ca

29 The PAH1-encoded phosphatidate phosphatase in Saccharomyces cerevisiae pl

30 Pah1 is the phosphatidate phosphatase in the yeast Saccharomyces cer

31 The mammalian lipin 1 phosphatidate phosphatase is a key regulatory enzyme in

32 Yeast PAH1-encoded phosphatidate phosphatase is the enzyme responsible for

33 al loss-of-function mutation in the gene for phosphatidate phosphatase Lpin1 and a truncation mutatio

34 The dependence of phosphatidate phosphatase on phosphatidate was cooperati

35 reviously that the activity of the conserved phosphatidate phosphatase Pah1p/Smp2p regulates nuclear

36 Phosphatidate phosphatase (PAP) catalyzes the dephosphor

37 The Saccharomyces cerevisiae PAH1-encoded phosphatidate phosphatase (PAP) catalyzes the penultimat

38 Lipin-1 functions as a phosphatidate phosphatase (PAP) enzyme in the glycerol 3

39 The three lipin phosphatidate phosphatase (PAP) enzymes catalyze a step

40 The family of three lipin proteins act as phosphatidate phosphatase (PAP) enzymes required for gly

41 re evolutionarily conserved Mg(2+)-dependent phosphatidate phosphatase (PAP) enzymes with essential r

42 -1, lipin-2, and lipin-3) are Mg2+-dependent phosphatidate phosphatase (PAP) enzymes, which catalyze

43 Pah1p, which functions as phosphatidate phosphatase (PAP) in the yeast Saccharomyc

44 Early work indicates a role of the phosphatidate phosphatase (PAP) in this metabolism; the

45 Phosphatidate phosphatase (PAP) plays diverse roles in l

46 Yeast App1p is a phosphatidate phosphatase (PAP) that associates with end

47 The PAH1-encoded phosphatidate phosphatase (PAP), which catalyzes the com

48 h a modulator of transcription factors and a phosphatidate phosphatase (PAP1), is known to play impor

49 myces cerevisiae PAH1-encoded Mg2+-dependent phosphatidate phosphatase (PAP1, 3-sn-phosphatidate phos

50 This result confirmed the role phosphatidate phosphatase plays in phosphatidylcholine s

51 doplasmic reticulum membrane to catalyze the phosphatidate phosphatase reaction.

52 anding of how phosphorylation of lipin 1beta phosphatidate phosphatase regulates its interaction with

53 hat catalyzes the dephosphory-lation of Pah1 phosphatidate phosphatase, required for its translocatio

54 Yeast Pah1p is the phosphatidate phosphatase that catalyzes the penultimate

55 c reticulum membrane localization of Pah1, a phosphatidate phosphatase that produces diacylglycerol f

56 Lipins are phosphatidate phosphatases that generate diacylglycerol

57 Lipins are evolutionarily conserved phosphatidate phosphatases that perform key functions in

58 ingle lipin homolog in yeast, Smp2, exhibits phosphatidate phosphatase type-1 (PAP1) activity, which

59 e showed that the expression of PAH1-encoded phosphatidate phosphatase was induced by zinc deficiency

60 including phosphatidylinositol synthase and phosphatidate phosphatase, were not affected in the cki1

61 Saccharomyces cerevisiae Pah1 phosphatidate phosphatase, which catalyzes the conversio

62 In Saccharomyces cerevisiae, Pah1 phosphatidate phosphatase, which catalyzes the dephospho

63 PAH1-encoded phosphatidate phosphatase, which catalyzes the dephospho

64 The yeast Pah1p phosphatidate phosphatase, which catalyzes the penultima

65 in lipid metabolism as an activator of Pah1 phosphatidate phosphatase, which produces diacylglycerol