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1 of the Kennedy pathway for the synthesis of phosphatidylcholine.
2 ture of cholesterol, phosphatidylserine, and phosphatidylcholine.
3 els at exchanging the human-like unsaturated phosphatidylcholine.
4 phatidylcholine can be semi-quantified using phosphatidylcholine.
5 idylation reaction of PLD's lipid substrate, phosphatidylcholine.
6 31 +/- 88 mg/d, of which 188 +/- 63 mg/d was phosphatidylcholine.
7 with equal amounts of phosphatidylserine and phosphatidylcholine.
8 ore desaturation of acyl groups occurring on phosphatidylcholine.
9 with membranes containing 2% PI(3)P and 98% phosphatidylcholine.
10 ynthesis of the essential membrane component phosphatidylcholine.
11 inds anionic phosphatidylserine over neutral phosphatidylcholine.
12 inal domain dimer with bound cholesterol and phosphatidylcholine.
13 ein) regulates the intermembrane transfer of phosphatidylcholine.
14 uires a fatty acid from the acyl-CoA pool or phosphatidylcholine.
15 rial membranes, phosphatidylethanolamine and phosphatidylcholine.
16 o extracts PI4P from the PM, in exchange for phosphatidylcholine.
17 asmic leaf is rich in phosphatidylserine and phosphatidylcholine.
18 les and formation of the hydrogen bonds with phosphatidylcholine.
19 mimics made of natural, "neutron invisible" phosphatidylcholines.
20 ssociated lysophospholipids and ether linked phosphatidylcholines.
21 wo major lipid species, triacylglycerols and phosphatidylcholines.
22 changes to metabolism of sphingomyelins and phosphatidylcholines.
23 ylarginine, tyramine, 2-hydroxybutyric acid, phosphatidylcholine (32:1), and taurochenodesoxycholic a
24 D in PREDIMED, 1.28 [95% CI, 1.13-1.47]) and phosphatidylcholine 32_0 (RR per SD in PREDIMED, 1.23 [9
25 We identified an association with relative phosphatidylcholine 38:3 (%PC 38:3) concentration, which
26 xed micelles of STC and 1-palmitoyl, 2-oleyl phosphatidylcholine, a phospholipid present in high prop
29 rnitine (C3-OH, p-value = 2.6 x 10(-4)), and phosphatidylcholine acyl-alkyl C38:4 (PC ae C38:4, p-val
30 ant differences in lysophosphatidylcholines, phosphatidylcholines, acylcarnitine, amino acids and sph
31 ed levels of alanine and decreased levels of phosphatidylcholine alkyl-acyl C42:5 and phosphatidylcho
33 (2 mM) Ca(2+) concentration on zwitterionic phosphatidylcholine and anionic phosphatidylserine lipid
34 icular lipid mixtures containing diphytanoyl-phosphatidylcholine and cholesterol plus different types
35 tory pathway that controls genes involved in phosphatidylcholine and fatty acid utilization and contr
36 sts and microsomal membranes, and hydrolyzes phosphatidylcholine and galactolipids to produce diacylg
38 palmitoyl phosphatidylcholine/egg 1,2-diacyl phosphatidylcholine and phenolic acids such as ferulic,
40 simulation of the whole TRPV1 embedded in a phosphatidylcholine and phosphatidylethanolamine membran
41 ynthesis of the most abundant phospholipids, phosphatidylcholine and phosphatidylethanolamine, respec
44 een of choline derivatives showed that total phosphatidylcholine and phosphatidylinositol (but not di
45 Pathway analysis revealed an association of phosphatidylcholine and sphingomyelin with inflammation
46 riacylglycerol, C54:9 triacylglycerol, C36:1 phosphatidylcholine and sucrose replicated in an indepen
47 almitate-enriched diacylglycerol between the phosphatidylcholine and triacylglycerol pathways, to the
48 ficant decrease in lysophosphatidylcholines, phosphatidylcholines and cholesterol esters and an incre
52 was characterized predominantly by saturated phosphatidylcholines and phosphatidylglycerols, which ar
53 rn representing higher levels of unsaturated phosphatidylcholines and phospholipid ethers, and lower
54 e outer leaf as consisting of sphingomyelin, phosphatidylcholine, and cholesterol and the inner leaf
57 n lipid membranes, phosphatidylethanolamine, phosphatidylcholine, and phosphatidylinositol, and found
58 ed from the chloroplast, reincorporated into phosphatidylcholine, and ultimately enter seed triacylgl
59 talk between these lysophosphatidylcholines, phosphatidylcholines, and coagulation and complement pro
60 unable to accumulate TAGs after heat stress, phosphatidylcholine appears to be the major fatty acid d
61 AsA) system mediated peroxidation of l-alpha-phosphatidylcholine aqueous dispersions stabilized by bi
63 lations show a selective enrichment of ether phosphatidylcholine around p24 proteins, which are recep
65 Membranes are composed of bulk lipids (e.g., phosphatidylcholine), as well as regulatory lipids that
66 D simulations with 1.4 mol% PI(4,5)P(2) in a phosphatidylcholine bilayer identified 8 binding sites w
68 c diclofenac exerted distinct alterations in phosphatidylcholine bilayers, which are used in this wor
69 ctures revealed two evolutionarily conserved phosphatidylcholine-binding mechanisms and their roles i
71 second and rate-limiting step of the de novo phosphatidylcholine biosynthesis is catalysed by CTP: ph
72 ing, we demonstrated that phosphocholine and phosphatidylcholine biosynthesis was markedly elevated i
73 e-bound photosynthetic apparatus and one for phosphatidylcholine biosynthesis, that were not known to
75 ne (PE) biosynthesis; however, exogenous NBD-phosphatidylcholine, Bodipy-PE, and TopFluor-cholesterol
76 ipid N-methyltransferases (PLMTs) synthesize phosphatidylcholine by methylating phosphatidylethanolam
77 cholesterol-rich (SCOR) lipid mixtures with phosphatidylcholine can be cosolubilized by n-dodecyl-be
78 ts, for example indicating that ether-linked phosphatidylcholine can be semi-quantified using phospha
79 n cells, particularly specific subspecies of phosphatidylcholine carrying very long polyunsaturated f
80 ne (PE)/phosphatidylglycerol) and mammalian (phosphatidylcholine/cholesterol (PC/Chol)) membranes.
81 art of the mechanism to preserve choline and phosphatidylcholine, choline transporter deficiency was
82 namic size increased with increasing l-alpha-phosphatidylcholine concentration (1.5-7.5 mM) for both
83 is a glycerophospholipid that, together with phosphatidylcholine, constitutes more than half of the t
86 cylglycerols, phosphatidylethanolamines, and phosphatidylcholines; decreases in abundance was observe
87 enzymes utilize a different and larger bulk phosphatidylcholine-derived DAG pool that is more slowly
90 10(-5)), tyrosine (p-value = 2.1 x 10(-4)), phosphatidylcholine diacyl C32:1 (PC aa C32:1, p-value =
91 esis, interact with the acyl-editing enzymes phosphatidylcholine: diacylglycerol cholinephosphotransf
92 rol acyltransferase mutant dgat1-1 (in which phosphatidylcholine:diacylglycerol acyltransferase (AtPD
93 on in camelina (Camelina sativa) of a lychee PHOSPHATIDYLCHOLINE:DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFE
94 ivity to relieve competition and knocked out phosphatidylcholine:diacylglycerol cholinephosphotransfe
96 ased levels of steroids, sphingomyelins, and phosphatidylcholines distinguished patients from control
97 rane surface in 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC)/1,2-dimyristoyl-sn-glycero-3-
98 cerol (DOPG), and 1,2-dioleoyl-sn-glycerol-3-phosphatidylcholine (DOPC) structurally stabilize the co
99 eta) composition is dominated by dipalmitoyl phosphatidylcholine (DPPC), which is the most prevalent
100 olines were synthesized from 1,2-dipalmitoyl phosphatidylcholine/egg 1,2-diacyl phosphatidylcholine a
101 sruption, but not LPS, caused an increase of phosphatidylcholine ether and cholesteryl esters in CD11
102 estatic liver injury due to impaired biliary phosphatidylcholine excretion, resulted in cirrhosis and
104 her- vs lower-molecular-weight carnitine and phosphatidylcholine family members in specific cardiac r
106 phodiesterase 6 (ENPP6)-act in sequence upon phosphatidylcholine found in MV membranes to produce pho
108 O), a gut microbiota metabolite from dietary phosphatidylcholine, has mechanistic links to atheroscle
109 wo of these phospholipids, sphingomyelin and phosphatidylcholine, have the highest GB of any small, m
110 ssing, stigmasterol (ST) and/or hydrogenated phosphatidylcholine (HPC) for the encapsulation lactofer
111 phospholipase D (PLD), which produces PA by phosphatidylcholine hydrolysis, and the CRY2-CIBN light-
112 es the exclusion of hydroxy fatty acids from phosphatidylcholine in developing transgenic Arabidopsis
119 istribution of Delta9 and Delta11 isomers of phosphatidylcholines in mouse brain and in human colon s
121 ocytes significantly reduced polyunsaturated phosphatidylcholines in the enterocyte plasma membrane a
122 e to the rich content of choline, especially phosphatidylcholine, in eggs because choline has been su
123 sion of genes important for the formation of phosphatidylcholine, including LYSOPHOSPHATIDYLCHOLINE A
124 t content; milk phosphatidylethanolamine and phosphatidylcholine increased by 22 and 26%, respectivel
126 hose in the highest compared with the lowest phosphatidylcholine intake quartile had 28% (95% CI: 1%,
130 is due to the channeling of fatty acids from phosphatidylcholine into TAG before being desaturated to
131 P-binding cassette transporter that extrudes phosphatidylcholine into the bile canaliculi of the live
132 in mineralizing cells and data showing that phosphatidylcholine is broken down in MVs during mineral
134 ynthesis of the major membrane phospholipid, phosphatidylcholine, is catalyzed by CTP:phosphocholine
135 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl) phosphatidylcholine (KOdiA-PC), a major type of oxidized
136 its both omega-6 and omega-3 desaturation in phosphatidylcholine, leading to a proportional change in
137 ular ions of the EGFR inhibitor erlotinib, a phosphatidylcholine lipid, and cholesterol, which were r
138 olemia induces HDL lipidomic changes, losing phosphatidylcholine-lipid species and gaining cholestery
139 hese results indicate that sphingomyelin and phosphatidylcholine lipids can act as charge-reducing ag
141 e activate B-cells via supported bilayers of phosphatidylcholine lipids, a natural ligand for the IgM
142 ity in extruded vesicles composed of neutral phosphatidylcholine lipids, including for the common cas
144 resonance (ESR) spectroscopy and in L-alpha-phosphatidylcholine liposome peroxidation assay measured
145 rimp lipid extract) were encapsulated in soy phosphatidylcholine liposomes with the addition of glyce
146 lation structures based on the entrapment of phosphatidylcholine liposomes, within a WPC matrix throu
148 ne (LPE) and 2-4-fold higher amounts of lyso phosphatidylcholine (LPC) compared to SP2/0 and CHO cell
149 diacylglycerol, phosphatidic acid, and lyso-phosphatidylcholine (LPC) have all been implicated in ER
150 cytosolic phospholipase A2 activity and lyso-phosphatidylcholine (Lyso-PC) levels in ALS patients sug
152 to negatively charged (phosphatidylserine or phosphatidylcholine) membranes than purely zwitterionic
155 esamol could be solubilised and entrapped in phosphatidylcholine mixed micelles (PCS) with 96.8% effi
158 t the A/W interface and penetration into egg phosphatidylcholine monolayer compared to lysozyme.
159 ipids, lysophosphatidylcholines (n = 11) and phosphatidylcholines (n = 61), and the protein members o
160 (NES = -1.77, P = 0.005, FDR P = 0.02), and phosphatidylcholines (NES = -1.72, P = 0.01, P = 0.03) w
162 resulted in defective bacterial growth when phosphatidylcholine or palmitic acid was used as the sol
163 choline) membranes than purely zwitterionic (phosphatidylcholine or phosphatidylethanolamine) ones.
165 S and oxidized 1-palmitoyl-2-arachidonoyl-sn-phosphatidylcholine (oxPAPC) dependent pro-inflammatory
166 centrations of fatty acids, cholesterol, and phosphatidylcholine (p < 0.01 at 72 h; 100 muM MPA) whic
167 ositional isomers, such as the regioisomeric phosphatidylcholines PC 16:0/18:1(n-9) and PC 18:1(n-9)/
170 In oilseed crops, PUFAs are synthesized on phosphatidylcholine (PC) and accumulated in triacylglyce
171 lates biosynthesis of the major phospholipid phosphatidylcholine (PC) and causes expansion of the end
174 ignals from the most abundant phospholipids (phosphatidylcholine (PC) and phosphatidylethanolamine (P
175 HH group showed significantly lower serum phosphatidylcholine (PC) and significantly higher phosph
176 atidylethanolamine (PE), sphingomyelin (SM), phosphatidylcholine (PC) and their molecular species wer
177 sity using gramicidin A channels embedded in phosphatidylcholine (PC) bilayers composed of equimolar
182 rporation of ferulic acid (FA) into egg-yolk phosphatidylcholine (PC) in a lipase-catalyzed acidolysi
183 in the chloroplast, followed by assembly of phosphatidylcholine (PC) in the endoplasmic reticulum (E
186 he ratio of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) is inverted (4 times higher in
187 strated via the charge inversion reaction of phosphatidylcholine (PC) lipid cations generated from ra
188 f diacylglyceryltrimethylhomo-Ser (DGTS) and phosphatidylcholine (PC) lipids measured in each cell.
190 h stabilize the protein, and polyunsaturated phosphatidylcholine (PC) or phosphatidylethanolamine (PE
193 ferase (CCT) is the key regulatory enzyme in phosphatidylcholine (PC) synthesis and is activated by b
194 ansferase (CCT), the rate-limiting enzyme in phosphatidylcholine (PC) synthesis, is an amphitropic en
198 cated that phosphatidylethanolamine (PE) and phosphatidylcholine (PC) were the major lipid components
199 s study investigated the effects of modified phosphatidylcholine (PC) with different alkyl chain leng
200 ologic effect of phosphatidylserine (PS) and phosphatidylcholine (PC), 2 phospholipids highly abundan
201 s a rate-limiting enzyme in the synthesis of phosphatidylcholine (PC), a predominant mitochondrial me
202 lethanolamine (PE), phosphatidylserine (PS), phosphatidylcholine (PC), and sphingomyelin (SM) cations
203 l attachment were inhibited by PS but not by phosphatidylcholine (PC), demonstrating that TIM-1-media
204 rous diacylglyceryltrimethylhomo-Ser (DGTS), phosphatidylcholine (PC), monogalactosyldiacylglycerol (
205 T and 0.2 mM at 2 T, while the headgroups of phosphatidylcholine (PC), phosphatidyl-ethanolamine (PE)
206 1p co-isolates with phosphatidylserine (PS), phosphatidylcholine (PC), phosphatidylethanolamine (PE),
207 composed of lipids containing head groups of phosphatidylcholine (PC), phosphatidylethanolamine (PE),
209 der AT and HT, the lipidome was dominated by phosphatidylcholine (PC), phosphatidylethanolamine (PE),
210 nDi allows complete and rapid methylation of phosphatidylcholine (PC), phosphatidylethanolamine (PE),
211 patial distribution of phospholipid classes, phosphatidylcholine (PC), phosphatidylethanolamines (PE)
212 Plants use several pathways to synthesize phosphatidylcholine (PC), the major phospholipid of euka
213 Beyond its function for the synthesis of phosphatidylcholine (PC), the methylation of PE facilita
215 ts identified a metabolic bottleneck between phosphatidylcholine (PC), the site of CPA biosynthesis,
216 , the product of the complete deacylation of phosphatidylcholine (PC), was long thought to not be a s
217 We demonstrate that cell-membrane-mimicking phosphatidylcholine (PC)-terminated monolayers improve t
226 es of Dnf2 are glucosylceramide (GlcCer) and phosphatidylcholine (PC, or their lyso-lipid derivatives
228 choline (KOdiA-PC), a major type of oxidized phosphatidylcholines (PC) found on oxLDL, has a high bin
229 nd phenylalanine), and glycerophospholipids (phosphatidylcholine [PC] aa C36:1 and Lyso-PC a C18:1).
230 ansfer of HFAs from their site of synthesis (phosphatidylcholine; PC) to triacylglycerol (TAG), espec
231 rt the direct CCS measurement of a series of phosphatidylcholines (PCs) and phosphatidylethanolamines
233 rides decreased in mixed field exposures and phosphatidylcholines (PCs) remained largely unchanged.
234 chromatography-tandem mass spectrometry (21 phosphatidylcholines (PCs), 7 lysophosphatidylethanolami
235 e of fish from polluted and reference sites; phosphatidylcholines (PCs), phosphatidylethanolamines (P
237 inosine were present in aqueous extracts and phosphatidylcholine, phosphatidylethanolamine and sphing
238 es in triglycerides (TG), diglycerides (DG), phosphatidylcholine, phosphatidylethanolamine, ceramide
239 protein particles, we incorporated ApoE into phosphatidylcholine/phosphatidylethanolamine liposomes a
240 esters, diacylglycerides, triacylglycerides, phosphatidylcholines, phosphatidylethanolamines, and sph
241 tive towards diverse phospholipids including phosphatidylcholine, phosphatidylinositol and phosphatid
242 xture of phospholipids, with high amounts of phosphatidylcholines, phosphatidylinositols (PI) and cho
243 broside, ceramide, phosphatidylethanolamine, phosphatidylcholine, phosphatidylserine, and phosphatidi
244 with factor Xa (FXa) and phospholipids (FXa/phosphatidylcholine-phosphatidylserine [PCPS]) vs LD100
245 ation of the oncogenic G12V-KRAS mutant in a phosphatidylcholine/phosphatidylserine bilayer, we first
246 mors (n = 34 cases), pseudouridine and C36:2 phosphatidylcholine plasmalogen had the strongest statis
247 n of fatty acyl chains into the sn-2 site of phosphatidylcholine, play important roles in pathophysio
248 (DMPG) and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine (POPC)/1-palmitoyl-2-oleoyl-sn-glyce
249 uctures of ELIC embedded in palmitoyl-oleoyl-phosphatidylcholine- (POPC-) only nanodiscs in both the
250 hesis was not detected, as acyl flux through phosphatidylcholine preceded the incorporation into TAG.
251 s increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine
252 ucture of a representative TCR bound to CD1b-phosphatidylcholine provides a molecular mechanism for t
253 redominately reactive to self antigens, like phosphatidylcholine (PtC), or antigens expressed by the
254 , we demonstrate the germline-like status of phosphatidylcholine (PtC)-specific (PtC(+)) peritoneal B
255 omoting genes such as CHPT1, which catalyzes phosphatidylcholine (PtdCho) synthesis and regulates cho
256 mulations of the mammalian StART-like PtdIns/phosphatidylcholine (PtdCho) transfer protein PITPalpha,
261 were loaded into liposomes prepared from soy phosphatidylcholine (SPC) with various stabilizers (chol
262 cholesteryl esters and a surface depleted of phosphatidylcholine species containing polyunsaturated a
263 plex mixture of phospholipids with different phosphatidylcholine species present in large amounts.
265 phocholine (ChoP), a reaction product of the phosphatidylcholine-specific phospholipase C (PC-PLC) of
266 entify in which complex lipid species (i.e., phosphatidylcholine, sphingolipids, etc) these FA differ
267 uded advanced glycation end products (AGEs), phosphatidylcholines, sphingolipids, saturated/unsaturat
269 lates lipid sensing by GCalpha and find that phosphatidylcholine stimulates PfPP1-dependent egress.
270 the incorporation of cholesterol in various phosphatidylcholine supported lipid bilayers by neutron
272 gs show that T. denticola possesses a unique phosphatidylcholine synthesis pathway combining conserve
273 ts indicate that enhanced phosphocholine and phosphatidylcholine synthesis supports the prolonged sur
275 y to separate and uniquely identify isomeric phosphatidylcholines that differ only in their position(
276 lamine also contributes to the production of phosphatidylcholine, the most abundant class of lipids i
277 mediated hydrolysis of arachidonic acid from phosphatidylcholine, thereby integrating the production
279 transport by transferring an acyl group from phosphatidylcholine to cholesterol, promoting the matura
281 ina sativa to test whether the conversion of phosphatidylcholine to DAG impacts TAG levels in seeds.
283 . the transfer of different acyl groups from phosphatidylcholine to monolysocardiolipin by yeast tafa
287 line or cholesterol, phosphatidylserine, and phosphatidylcholine, two low-affinity MPP(+) binding sit
288 at PvrA directly regulates genes involved in phosphatidylcholine utilization and fatty acid catabolis
292 yso phosphatidylcholine was synthesized from phosphatidylcholine via regioselective enzymatic hydroly
296 concentrations of free choline, betaine, and phosphatidylcholine were measured with the use of liquid
298 cis and trans forms of triacylglycerols and phosphatidylcholines were identified by this DMS-EIEIO w
300 thyl group-dependent endogenous synthesis of phosphatidylcholine, which is needed for lipoprotein syn