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1 luconeogenic genes glucose-6-phosphatase and phosphoenolpyruvate carboxykinase.
2 explained by increased expression of hepatic phosphoenolpyruvate carboxykinase.
3 uconeogenic genes, glucose-6-phosphatase and phosphoenolpyruvate carboxykinase.
4 RNA levels of the key gluconeogenetic enzyme phosphoenolpyruvate carboxykinase.
5 uconeogenic enzymes glucose-6-phosphtase and phosphoenolpyruvate carboxykinase.
6 coneogenic enzymes glucose-6-phosphatase and phosphoenolpyruvate carboxykinase.
7 cose-6-phosphatase and the cytosolic form of phosphoenolpyruvate carboxykinase.
8 ls for the enzymes glucose-6-phosphatase and phosphoenolpyruvate carboxykinase.
9 eased transcription of the gene that encodes phosphoenolpyruvate carboxykinase 1 (a protein involved
10 re detail and indicated that the activity of phosphoenolpyruvate carboxykinase 1 (AT4G37870), a key e
11 nhibited hepatic gluconeogenic genes such as phosphoenolpyruvate carboxykinase 1 (Pck-1) and glucose
12 g2 and Yy1 induced key gluconeogenic enzymes phosphoenolpyruvate carboxykinase 1 (PCK1) and glucose-6
13 ts as a coactivator for transcription of the phosphoenolpyruvate carboxykinase 1 (PCK1) gene to incre
14 nic enzymes glucose-6-phosphatase (G6PC) and phosphoenolpyruvate carboxykinase 1 (PCK1) has negative
15 erosis/cataplerosis via genetic knockdown of phosphoenolpyruvate carboxykinase 1 (Pck1) prevented fat
16 D3/ICOS beads were rescued by overexpressing phosphoenolpyruvate carboxykinase 1 (PCK1), a PEP regula
18 cluding liver glycogen phosphorylase (PYGL), phosphoenolpyruvate carboxykinase 1 (PCK1), and the gluc
19 rcinoma (HCC) cells phosphorylates cytosolic phosphoenolpyruvate carboxykinase 1 (PCK1), the rate-lim
20 ing PEP production through overexpression of phosphoenolpyruvate carboxykinase 1 (PCK1), which bolste
21 ticoid regulated kinase 2 (SGK2) to activate phosphoenolpyruvate carboxykinase 1 (PEPCK1) and glucose
22 leled by elevated serum glucagon and hepatic phosphoenolpyruvate carboxykinase 1 (PEPCK1) expression,
25 We determined MNR effects on fetal liver phosphoenolpyruvate carboxykinase 1 (protein, PEPCK1; ge
27 d dexamethasone-induced transcription of the phosphoenolpyruvate carboxykinase 1 gene was strikingly
28 t with TCPOBOP or PB decreased the levels of phosphoenolpyruvate carboxykinase 1 mRNA in mice but not
29 ith a glucocorticoid response element in the phosphoenolpyruvate carboxykinase 1 promoter in a hormon
30 l hepatic levels of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase 1 were increased in hP
31 EDV administration increased mRNA levels for phosphoenolpyruvate carboxykinase 1, argininosuccinate s
32 the rate-limiting enzyme in gluconeogenesis, phosphoenolpyruvate carboxykinase 1, is regulated throug
33 ify downregulation of metabolism transcripts Phosphoenolpyruvate carboxykinase-1, 4-Hydroxyphenylpyru
34 ally, Lin28a directly bound to mitochondrial phosphoenolpyruvate carboxykinase 2 ( Pck2) mRNA and inc
35 hosphoenolpyruvate carboxykinase (PEPCK) and phosphoenolpyruvate carboxykinase 2 (PCK2) to reprogram
36 with shizukaol F decreased the expression of phosphoenolpyruvate carboxykinase 2 (PEPCK), glucose-6-p
37 king this novel process with an inhibitor of phosphoenolpyruvate carboxykinase (3-mercaptopicolinic a
38 lucose levels and hepatic mRNA expression of phosphoenolpyruvate carboxykinase, a well known rate-lim
39 lectron transfer flavoprotein subunit alpha, phosphoenolpyruvate carboxykinase, aconitate hydratase,
43 a not only with the rPDK4 gene but also with phosphoenolpyruvate carboxykinase and CPT-1a (carnitine
44 PST administration in KO mice stimulated phosphoenolpyruvate carboxykinase and G6Pase mRNA abunda
45 atic expression of the gluconeogenic enzymes phosphoenolpyruvate carboxykinase and G6Pase mRNAs was r
46 vates expression of gluconeogenic, including phosphoenolpyruvate carboxykinase and glucose-6-phosphat
47 ession of key gluconeogenic genes, including phosphoenolpyruvate carboxykinase and glucose-6-phosphat
48 of hepatic mRNA for the cytosolic isoform of phosphoenolpyruvate carboxykinase and glucose-6-phosphat
49 ctivate key genes of gluconeogenesis such as phosphoenolpyruvate carboxykinase and glucose-6-phosphat
50 major regulators of hepatic gluconeogenesis, phosphoenolpyruvate carboxykinase and glucose-6-phosphat
52 ssion of two critical gluconeogenic enzymes, phosphoenolpyruvate carboxykinase and glucose-6-phosphat
53 epatocyte genes involved in gluconeogenesis (phosphoenolpyruvate carboxykinase and glycogen synthase)
55 orrelation between dynamics and catalysis in phosphoenolpyruvate carboxykinase and other enzymes in w
57 n of the expression of two key genes: PEPCK (phosphoenolpyruvate carboxykinase) and SREBP-1c (sterol
58 e expression of liver gluconeogenic enzymes, phosphoenolpyruvate carboxykinase, and fructose-1,6-bisp
60 y acid synthase, liver-type pyruvate kinase, phosphoenolpyruvate carboxykinase, and type I deiodinase
62 pyruvate kinase), and gluconeogenic enzymes (phosphoenolpyruvate carboxykinase), as well as the diet-
63 coneogenic enzymes glucose-6 phosphatase and phosphoenolpyruvate carboxykinase, as well as a marked i
66 ugh pyruvate carboxylation (anaplerosis) and phosphoenolpyruvate carboxykinase (cataplerosis) and dec
67 the nematode analog of the cytosolic form of phosphoenolpyruvate carboxykinase caused a marked extens
68 te (PEP) and oxaloacetate (OAA) by cytosolic phosphoenolpyruvate carboxykinase (cPEPCK) were investig
69 ng to the cAMP response element found in the phosphoenolpyruvate carboxykinase-cytosolic (PEPCK-C) pr
71 , transaldolase, fructose bisphosphatase and phosphoenolpyruvate carboxykinase (encoded by ICL1, MAS1
72 n increase in the liver gluconeogenic enzyme phosphoenolpyruvate carboxykinase expression and activit
74 orrelated well with the observed increase in phosphoenolpyruvate carboxykinase expression, type IA fi
75 to regulate major metabolic genes including phosphoenolpyruvate carboxykinase, fatty acid synthase,
76 gluconeogenic enzymes glucose-6-phosphatase, phosphoenolpyruvate carboxykinase, fructose-1,6-phosphat
77 locomplex and regulates expression of PEPCK (phosphoenolpyruvate carboxykinase), G6P (glucose-6-phosp
78 receptor substrate-1 (IRS-1), and it reduces phosphoenolpyruvate carboxykinase gene expression in a p
79 factor 1 (gAF1) and 3 (gAF3) elements in the phosphoenolpyruvate carboxykinase gene glucocorticoid re
80 rifampicin effects were also observed in the phosphoenolpyruvate carboxykinase gene that contains a f
82 cessory factor for the complete induction of phosphoenolpyruvate carboxykinase gene transcription by
83 ng response elements for insulin (in the rat phosphoenolpyruvate carboxykinase gene), glucocorticoids
85 glucose production and hepatic expression of phosphoenolpyruvate carboxykinase, glucose-6-phosphatase
86 vity in the liver of L-iNOS-Tg mice, whereas phosphoenolpyruvate carboxykinase, glucose-6-phosphatase
87 oid-regulated hepatic gluconeogenic enzymes, phosphoenolpyruvate carboxykinase, glucose-6-phosphatase
89 iption of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (EC ) (PEPCK-C).
91 lear factor I (NFI) binds to a region of the phosphoenolpyruvate carboxykinase (GTP) (PEPCK) gene pro
93 iption of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) (PEPCK-C) (4.1.1
94 aining a chimeric gene in which the cDNA for phosphoenolpyruvate carboxykinase (GTP) (PEPCK-C) (EC 4.
97 coneogenic enzymes glucose-6-phosphatase and phosphoenolpyruvate carboxykinase in the leptin-infused
99 f ROR target genes, including Glc-6-Pase and phosphoenolpyruvate carboxykinase, in an ROR-dependent m
100 acted by mercaptopicolinate, an inhibitor of phosphoenolpyruvate carboxykinase, indicating that it is
101 enic enzymes fructose-1,6-bisphosphatase and phosphoenolpyruvate carboxykinase, is repressed by gluco
102 sat1 and Psph) and the gluconeogenic enzyme, phosphoenolpyruvate carboxykinase-M (Pck2/PEPCK-M), incr
105 cokinase mRNA was decreased, whereas that of phosphoenolpyruvate carboxykinase mRNA was increased com
106 ed cAMP response element binding protein and phosphoenolpyruvate carboxykinase mRNA were profoundly r
108 (4 h) suppressed hepatic glucose production, phosphoenolpyruvate carboxykinase mRNA, and plasma FFA t
109 vity of the key gluconeogenic pathway enzyme phosphoenolpyruvate carboxykinase (Pck) also increased u
110 e (NAD) phosphate malic enzyme (NADP-ME) and phosphoenolpyruvate carboxykinase (PCK) photosynthetic p
115 ate weak interactions between MDH2 and yeast phosphoenolpyruvate carboxykinase (PCK1) and between MDH
116 pression of the hepatic gluconeogenic genes, phosphoenolpyruvate carboxykinase (PCK1) and glucose-6-p
117 n regulating glucose metabolism by targeting phosphoenolpyruvate carboxykinase (PCK1) and glucose-6-p
118 elates with glucose-6-phosphatase (G6PC) and phosphoenolpyruvate carboxykinase (PCK1) expression, key
119 known to regulate the activity of cytosolic phosphoenolpyruvate carboxykinase (PCK1), a key enzyme i
120 these, acetylation sites (Lys19 and 514) of phosphoenolpyruvate carboxykinase (Pck1p) were determine
122 ges lacking the initial gluconeogenic enzyme phosphoenolpyruvate carboxykinase (PCK2, mitochondrial i
126 amme of key gluconeogenic enzymes, including phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-
127 gluconeogenetic and glycogenolytic enzymes, phosphoenolpyruvate carboxykinase (Pepck) and glucose-6-
128 es that encode gluconeogenic enzymes such as phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-
129 lycemia was associated with normal levels of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-
130 d to increased transcriptional expression of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-
131 patic expression of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase (PEPCK) and impairs in
132 The insulin response elements (IREs) of the phosphoenolpyruvate carboxykinase (PEPCK) and insulin-li
133 pts for archetypical decarboxylation enzymes phosphoenolpyruvate carboxykinase (PEPCK) and malic enzy
134 ncer cells utilize the gluconeogenic enzymes phosphoenolpyruvate carboxykinase (PEPCK) and phosphoeno
135 nvestigate the effect of decreased cytosolic phosphoenolpyruvate carboxykinase (PEPCK) and plastidic
136 transcriptional regulation of Glc-6-Pase and phosphoenolpyruvate carboxykinase (PEPCK) by apoA-IV was
137 c DNA vaccine encoding Leishmania glycosomal phosphoenolpyruvate carboxykinase (PEPCK) by EP and agai
142 ructural studies of the gluconeogenic enzyme phosphoenolpyruvate carboxykinase (PEPCK) demonstrate th
144 response in two independent assays: reducing phosphoenolpyruvate carboxykinase (PEPCK) expression in
147 TP binding motif and takes a fold similar to phosphoenolpyruvate carboxykinase (PEPCK) from Escherich
148 human CYP7A1 gene in bile acid synthesis and phosphoenolpyruvate carboxykinase (PEPCK) gene in glucon
149 TTG sequence, which is the core motif of the phosphoenolpyruvate carboxykinase (PEPCK) gene IRS.
154 ide here such an example by showing that the phosphoenolpyruvate carboxykinase (PEPCK) gene knockout
155 cyclic AMP response element (CRE) of the rat phosphoenolpyruvate carboxykinase (PEPCK) gene promoter
156 etinoic acid response element (RARE1) in the phosphoenolpyruvate carboxykinase (PEPCK) gene promoter
160 rticoids cause a 10-fold increase in hepatic phosphoenolpyruvate carboxykinase (PEPCK) gene transcrip
162 ucocorticoid and cAMP-stimulated increase in phosphoenolpyruvate carboxykinase (PEPCK) gene transcrip
163 ular mechanisms underlying increased hepatic phosphoenolpyruvate carboxykinase (PEPCK) gene transcrip
164 ated transgenic (TG) mice overexpressing the phosphoenolpyruvate carboxykinase (PEPCK) gene under con
165 increase in the rate of transcription of the phosphoenolpyruvate carboxykinase (PEPCK) gene, which en
168 y in mice to determine the role of cytosolic phosphoenolpyruvate carboxykinase (PEPCK) in hepatic ene
169 ic gluconeogenesis through downregulation of phosphoenolpyruvate carboxykinase (PEPCK) in wild-type (
170 h enhanced activation of Akt, which inhibits phosphoenolpyruvate carboxykinase (PEPCK) induction, cau
180 ion of glucocorticoid receptor (GR) mRNA and phosphoenolpyruvate carboxykinase (PEPCK) mRNA (and acti
182 be identical with one present in the enzyme phosphoenolpyruvate carboxykinase (PEPCK) of the organis
183 ic mice that express rabbit CRP from the rat phosphoenolpyruvate carboxykinase (PEPCK) promoter in re
184 aling in renal epithelial cells, we used the phosphoenolpyruvate carboxykinase (PEPCK) promoter to ge
186 The insulin response sequence (IRS) of the phosphoenolpyruvate carboxykinase (PEPCK) promoter, loca
187 antigen (TAg), each under the control of the phosphoenolpyruvate carboxykinase (PEPCK) promoter, were
189 e pH dependence of the reaction catalyzed by phosphoenolpyruvate carboxykinase (PEPCK) provides signi
190 e structures of the rat cytosolic isoform of phosphoenolpyruvate carboxykinase (PEPCK) reported in th
192 of both glucose-6-phosphatase (Glc-6-P) and phosphoenolpyruvate carboxykinase (Pepck) to an extent s
196 eport crystal structures of the human enzyme phosphoenolpyruvate carboxykinase (PEPCK) with and witho
197 utes to TCDD suppression of transcription of phosphoenolpyruvate carboxykinase (PEPCK), a key regulat
200 receptor gamma coactivator-1 alpha (PGC-1), phosphoenolpyruvate carboxykinase (PEPCK), and glucose-6
201 tion, expression of key gluconeogenic genes, phosphoenolpyruvate carboxykinase (PEPCK), and glucose-6
202 vestigated the role of glycerol kinase (GK), phosphoenolpyruvate carboxykinase (PEPCK), and pyruvate
203 decarboxylation of [4-(13)C]oxaloacetate via phosphoenolpyruvate carboxykinase (PEPCK), forward TCA c
204 d) could activate p38 and increase levels of phosphoenolpyruvate carboxykinase (PEPCK), glucose-6-pho
206 ough the insulin-responsive sequences of the phosphoenolpyruvate carboxykinase (PEPCK), IGFBP-1, and
207 receptor gamma co-activator-1a (PGC-1alpha), phosphoenolpyruvate carboxykinase (PEPCK), pyruvate carb
209 ted glucocorticoid induction of the gene for phosphoenolpyruvate carboxykinase (PEPCK), the rate-limi
211 pression of glucose-6-phosphatase (G6PC) and phosphoenolpyruvate carboxykinase (Pepck), two gluconeog
234 creased gluconeogenic flux through cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) and associat
236 tigated whether the mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) is the GTPas
240 colinic acid (3-MPA), a classic inhibitor of phosphoenolpyruvate carboxykinase, photosynthetic O(2) e
241 coneogenic enzymes glucose-6-phosphatase and phosphoenolpyruvate carboxykinase, presumably, because o
242 ge-dependent phosphoenolpyruvate carboxylase/phosphoenolpyruvate carboxykinase process that decreases
243 essing rabbit CRP (CF1-CRP) regulated by the phosphoenolpyruvate carboxykinase promoter such that lev
244 SV40 T-Antigen in liver under control of the phosphoenolpyruvate carboxykinase promoter were generate
247 diate complexes of the reaction catalyzed by phosphoenolpyruvate carboxykinase provide direct structu
248 ive human TGF-beta1 under control of the rat phosphoenolpyruvate carboxykinase regulatory sequences d
249 e, transaldolase, alcohol dehydrogenase, and phosphoenolpyruvate carboxykinase) that indicate the pot
250 rboxylic acid (TCA) cycle first and then use phosphoenolpyruvate carboxykinase to initiate gluconeoge
251 of expression of several HNF3 target genes (phosphoenolpyruvate carboxykinase, transferrin, tyrosine
252 rget genes such as glucose-6-phosphatase and phosphoenolpyruvate carboxykinase, two key targets for F
253 regulated by insulin such as those encoding phosphoenolpyruvate carboxykinase, tyrosine aminotransfe
254 ulation of PPARgamma-inducible genes such as phosphoenolpyruvate carboxykinase was maintained when ce
255 psin, aldolase B, alcohol dehydrogenase, and phosphoenolpyruvate carboxykinase, was also affected in
256 Levels of cytosolic and the mitochondrial phosphoenolpyruvate carboxykinase were elevated after 24
257 decarboxylase systems (NADP-malic enzyme and phosphoenolpyruvate carboxykinase) were critical for mat
258 gluconeogenic enzymes, isocitrate lyase and phosphoenolpyruvate carboxykinase, were also degraded in
259 and the gluconeogenesis controller, hepatic phosphoenolpyruvate carboxykinase, were significantly el
260 egulation of the first gluconeogenic enzyme, phosphoenolpyruvate carboxykinase, when acetate was the