ライフサイエンスコーパス: phosphoglycerate

1 w concentrations (10 microM) of activator (3-phosphoglycerate).

2 ast types have the capacity to photoreduce 3-phosphoglycerate.

3 and glycerate to enter central metabolism at phosphoglycerate.

4 the phosphotransferase reaction regenerating phosphoglycerate.

5 ed by G6P but is inhibited by both PEP and 3-phosphoglycerate.

6 ubisCO continues to fix CO2 and synthesize 3-phosphoglycerate.

7 s substrate 3-phosphoglycerate and product 2-phosphoglycerate.

8 orms the unstable organoarsenical 1-arseno-3-phosphoglycerate (1As3PGA).

9 e, 3-phosphoglycerate (3-PG), and product, 2-phosphoglycerate (2-PG).

10 ns in the enolase-catalyzed dehydration of 2-phosphoglycerate (2-PGA).

11 sphoglycerate (1, 3-BPG) to ADP, producing 3-phosphoglycerate (3-PG) and ATP.

12 phospho-transfer reaction between ATP and 3-phosphoglycerate (3-PG) that is thought to require a hin

13 ing intracellular levels of its substrate, 3-phosphoglycerate (3-PG), and product, 2-phosphoglycerate

14 When 3-phosphoglycerate (3-PGA), the putative physiological act

15 regulators such as inorganic phosphate and 3-phosphoglycerate (3-PGA).

16 d an enzyme, P52L, that was insensitive to 3-phosphoglycerate (3-PGA).

17 here it rapidly dissociates into As(V) and 3-phosphoglycerate (3PGA), creating a novel pathway of ars

18 similar and the active site contains both 3-phosphoglycerate and 2-phosphoglycerate at equal occupan

19 cer cells and contributes to regulation of 3-phosphoglycerate and 2-phosphoglycerate levels, promotin

20 e quantification of the individual isomers 2-phosphoglycerate and 3-phosphoglycerate, as well as gluc

21 atalyzes phosphoryl transfer between 1,3-bis-phosphoglycerate and ADP to form 3-phosphoglycerate and

22 n 1,3-bis-phosphoglycerate and ADP to form 3-phosphoglycerate and ATP.

23 ling intracellular levels of its substrate 3-phosphoglycerate and product 2-phosphoglycerate.

24 L subunit had a high apparent affinity for 3-phosphoglycerate and substrates suggesting a leading rol

25 the structure of this iPGM complexed with 2-phosphoglycerate and two Mn(2+) ions at 1.7-A resolution

26 f the model leading to the accumulation of 3-phosphoglycerate and/or pyruvate.

27 PGMs) catalyze the isomerization of 2- and 3-phosphoglycerates and are essential for glucose metaboli

28 NADPH, 3-phosphoglycerate, and ATP were competitive inhibitors, a

29 ation of internal ribulose-1,5-bisphosphate, phosphoglycerate, and Ci pools when grown under comparab

30 ramatic changes in their responses to AMP, 3-phosphoglycerate, and pyruvate but not to NADPH and isoc

31 AMP, 3-phosphoglycerate, and pyruvate represent a class of regu

32 onversion efficiency through generation of 3-phosphoglycerate; and (iv) a larger contribution of amin

33 individual isomers 2-phosphoglycerate and 3-phosphoglycerate, as well as glucose-6-phosphate and fru

34 and ribulose bisphosphate and the product 3-phosphoglycerate associated with their transition throug

35 site contains both 3-phosphoglycerate and 2-phosphoglycerate at equal occupancies (50%).

36 (Lm iPGAM) crystallised with the substrate 3-phosphoglycerate at high and low cobalt concentrations h

37 M1 at least in part by promoting substrate 3-phosphoglycerate binding.

38 al low apparent affinity for the activator 3-phosphoglycerate, but it was atypically defective in the

39 lso formed by the TCA cycle, is converted to phosphoglycerate by a reaction sequence that is reversed

40 s the conversion of arsenate into 1-arseno-3-phosphoglycerate by PvGAPC1.

41 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escher

42 e catalytic activity of Escherichia coli D-3-phosphoglycerate dehydrogenase (PGDH) by binding to its

43 Phosphoglycerate dehydrogenase (PGDH) catalyzes the firs

44 Escherichia coli 3-phosphoglycerate dehydrogenase (PGDH) catalyzes the firs

45 An active conformation of phosphoglycerate dehydrogenase (PGDH) from Escherichia c

46 D-3-Phosphoglycerate dehydrogenase (PGDH) from Escherichia c

47 ructural homology with the ASB domain of d-3-phosphoglycerate dehydrogenase (PGDH) from Mycobacterium

48 D-3-Phosphoglycerate dehydrogenase (PGDH) from Mycobacterium

49 ric hybrid tetramers of Escherichia coli d-3-phosphoglycerate dehydrogenase (PGDH) have been made by

50 topped-flow analysis of Escherichia coli d-3-phosphoglycerate dehydrogenase (PGDH) reveals that the p

51 ol coefficient for the branch point enzyme 3-phosphoglycerate dehydrogenase (PGDH).

52 ding for the first enzyme of this pathway, 3-phosphoglycerate dehydrogenase (PGDH).

53 ulatory and substrate binding domains of D-3-phosphoglycerate dehydrogenase (PGDH, EC 1.1.1.95) from

54 Individual gene effects were notable for phosphoglycerate dehydrogenase (PGHDH), peptidyl-prolyl

55 nately regulate expression of genes encoding phosphoglycerate dehydrogenase (PHGDH) and five downstre

56 Enzymes of the SSP, such as phosphoglycerate dehydrogenase (PHGDH) and phosphoserine

57 Phosphoglycerate dehydrogenase (PHGDH) catalyzes the fir

58 Astrocytes express the 3-phosphoglycerate dehydrogenase (Phgdh) enzyme required f

59 Among the genes identified, phosphoglycerate dehydrogenase (PHGDH) is in a genomic r

60 Phosphoglycerate dehydrogenase (PHGDH) is the metabolic

61 ction of circulating serine by inhibition of phosphoglycerate dehydrogenase (PHGDH) leads to the accu

62 BA, but not GH, caused a 2-fold increase in phosphoglycerate dehydrogenase (PHGDH) protein expressio

63 nificance with multiple testing adjustments, phosphoglycerate dehydrogenase (PHGDH) was the only gene

64 mes of the de novo serine synthesis pathway (phosphoglycerate dehydrogenase (PHGDH), phosphoserine am

65 Phosphoglycerate dehydrogenase (PHGDH), the first rate-l

66 uman cancers often exhibit overexpression of phosphoglycerate dehydrogenase (PHGDH), the metabolic en

67 0) show that MEKi-resistant cells upregulate phosphoglycerate dehydrogenase (PHGDH), the rate-limitin

68 The gene encoding the enzyme 3-phosphoglycerate dehydrogenase (PHGDH), which catalyzes

69 d into serine and glycine metabolism through phosphoglycerate dehydrogenase (PHGDH).

70 Macular Muller cells expressed more phosphoglycerate dehydrogenase (PHGDH, a rate-limiting e

71 d-3-Phosphoglycerate dehydrogenase (Phgdh; EC 1.1.1.95) is t

72 xtracts of M. maripaludis were shown to have phosphoglycerate dehydrogenase and phosphoserine aminotr

73 The inhibition of Escherichia coli d-3-phosphoglycerate dehydrogenase by l-serine is positively

74 resents a second structural motif of the D-3-phosphoglycerate dehydrogenase family, one that contains

75 The binding of L-serine to phosphoglycerate dehydrogenase from E. coli displays ele

76 d-3-Phosphoglycerate dehydrogenase from Escherichia coli con

77 d-3-Phosphoglycerate dehydrogenase from Escherichia coli is

78 The heterologously expressed and purified phosphoglycerate dehydrogenase from M. maripaludis had e

79 D-3-Phosphoglycerate dehydrogenase from Mycobacterium tuberc

80 The crystal structure of D-3-phosphoglycerate dehydrogenase from Mycobacterium tuberc

81 structure of Mycobacterium tuberculosis d-3-phosphoglycerate dehydrogenase has been solved with boun

82 10 interacted with the chloroplastic protein phosphoglycerate dehydrogenase in a yeast (Saccharomyces

83 3-Phosphoglycerate dehydrogenase is an exclusively astrocy

84 The crystal structure of d-3-phosphoglycerate dehydrogenase reveals a limited number

85 The first D-3-phosphoglycerate dehydrogenase structure to be determine

86 sphate pathway (PPP), while 2-PG activates 3-phosphoglycerate dehydrogenase to provide feedback contr

87 Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase undergoes significant inh

88 topped flow analysis of Escherichia coli D-3-phosphoglycerate dehydrogenase was performed by followin

89 e structure of a truncated form of human d-3-phosphoglycerate dehydrogenase with cofactor and a subst

90 ns indirectly enhance the ability of SerA (3-phosphoglycerate dehydrogenase) to perform a new functio

91 Strains lacking yggS and serA (3-phosphoglycerate dehydrogenase) were conditionally letha

92 d genes associated with serine biosynthesis (Phosphoglycerate dehydrogenase, Phgdh; phosphoserine ami

93 In Escherichia colid-3-phosphoglycerate dehydrogenase, the amino acid sequences

94 n part to the genomic copy number gain for 3-phosphoglycerate dehydrogenase, the enzyme that controls

95 Consistently, inhibition of phosphoglycerate dehydrogenase, the first enzyme of the

96 and mice with targeted deletion of Srr or 3-Phosphoglycerate dehydrogenase, we demonstrate predomina

97 same fold; (iii) the C-terminal domain of 3-phosphoglycerate dehydrogenase, which binds serine and i

98 te of the ACT-domain of the Escherichia coli phosphoglycerate dehydrogenase.

99 e, we present a detailed characterization of phosphoglycerate dehydrogenases (PGDHs) as components of

100 with the ASB domain like that in type 1 D-3-phosphoglycerate dehydrogenases (PGDHs).

101 Phosphoglycerate dehydrogenases exist in at least three

102 version of 3-phosphoglyceroyl phosphate to 3-phosphoglycerate, exhibited inositol auxotrophy.

103 reaction removing the phosphate from 2- or 3-phosphoglycerate, generating an enzyme-bound phosphoseri

104 Once inside these vesicles, 1-arseno-3-phosphoglycerate hydrolyses to release arsenate, which i

105 PGK) converts 1,3-bisphosphoglycerate into 3-phosphoglycerate in glycolysis but also participates in

106 ses catalyze the interconversion of 2- and 3-phosphoglycerate in the glycolytic and gluconeogenic pat

107 3, which are primarily known for oxidizing 3-phosphoglycerate in the main serine biosynthesis pathway

108 the biosynthesis and transport of 1-arseno-3-phosphoglycerate, indicating that P. vittata has evolved

109 the other hand, sensitivity to citrate and 3-phosphoglycerate inhibition was lost, indicating an impo

110 Glycolytic interconversion of phosphoglycerate isomers is catalysed in numerous pathog

111 dehyde phosphate dehydrogenase (GAPDH) and 3-phosphoglycerate kinase (3-PGK) are enriched in synaptic

112 eviously, we identified that the chloroplast phosphoglycerate kinase (chl-PGK) from Nicotiana bentham

113 ng intermediates of the N-terminal domain of phosphoglycerate kinase (N-PGK) and a number of conserva

114 he chemically denatured N-terminal domain of phosphoglycerate kinase (N-PGK) has been determined by p

115 Phosphoglycerate kinase (PGK) catalyzes a reversible pho

116 The glycolytic enzyme phosphoglycerate kinase (PGK) catalyzes phosphoryl trans

117 In plants, phosphoglycerate kinase (PGK) converts 1,3-bisphosphogly

118 On a dataset of eukaryotic proteins from the phosphoglycerate kinase (PGK) family, interdomain site c

119 the stability and folding relaxation rate of phosphoglycerate kinase (PGK) Forster resonance energy t

120 Previous studies of the N-domain of phosphoglycerate kinase (PGK) from Bacillus stearothermo

121 anidinium-denatured state of the N-domain of phosphoglycerate kinase (PGK) has been characterized usi

122 ion state analogue (TSA) complexes formed by phosphoglycerate kinase (PGK) have been used to test the

123 y and folding rate of a mutant of the enzyme phosphoglycerate kinase (PGK) inside bone tissue cells a

124 The pneumococcal glycolytic enzyme phosphoglycerate kinase (PGK) is both secreted and bound

125 Escherichia coli phosphoglycerate kinase (PGK) is resistant to proteolyti

126 Incorporation of these fragments upstream of phosphoglycerate kinase (PGK) or cytomegalovirus promote

127 rexpression of PDGFB using a relatively weak phosphoglycerate kinase (PGK) promoter completely avoide

128 Cs transduced by a vector that used a murine phosphoglycerate kinase (PGK) promoter led to a complete

129 cetyl-CoA carboxylase (ACCase) and plastid 3-phosphoglycerate kinase (PGK) to study grass evolution.

130 stigation of the interaction of the enzyme 3-phosphoglycerate kinase (PGK) with aryl and alkyl bispho

131 compaction of the already unfolded state of phosphoglycerate kinase (PGK) with decreasing denaturant

132 Phosphoglycerate kinase (PGK), a downstream protein of h

133 The nubian mutant disrupts phosphoglycerate kinase (PGK), an enzyme required for AT

134 We have used phosphoglycerate kinase (PGK), an enzyme that forms its

135 for inhibiting Trypanosoma brucei glycosomal phosphoglycerate kinase (PGK), glyceraldehyde-3-phosphat

136 Phosphoglycerate kinase (PGK), present on the surface of

137 d results for a hinge-bending enzyme, namely phosphoglycerate kinase (PGK), which support and extend

138 factor HIF-1, glucose transporter (GLUT)-1, phosphoglycerate kinase (PGK)-1, and vascular endothelia

139 ng investigation of the impact of a retained phosphoglycerate kinase (PGK)-neo cassette located betwe

140 tructure, function, and folding landscape of phosphoglycerate kinase (PGK).

141 mediate state of the large two-domain enzyme phosphoglycerate kinase (PGK).

142 analog diphosphates are phosphorylated by 3-phosphoglycerate kinase (PGK).

143 f proline 204 in the 'hinge' region of yeast phosphoglycerate kinase (PGK).

144 ng landscape of a FRET-labeled enzyme, yeast phosphoglycerate kinase (PGK-FRET).

145 e redox features of the Calvin-Benson enzyme phosphoglycerate kinase (PGK1) from the eukaryotic green

146 n the transcriptionally active human p53 and phosphoglycerate kinase (pgk1) genes in vivo.

147 dehyde-3-phosphate dehydrogenase (Gap1); and phosphoglycerate kinase (Pgk1).

148 e was confirmed by expressing the glycosomal phosphoglycerate kinase (PGKC) in the Deltappdk/Deltapep

149 xins 1 and 6), and metabolic proteins (e.g., phosphoglycerate kinase 1 (PGK 1), alpha enolase, aldola

150 Since other Hif target genes such phosphoglycerate kinase 1 (Pgk) were Hif-1alpha dependen

151 Phosphoglycerate kinase 1 (PGK1) catalyzes the reversibl

152 8 phosphorylation, leading to ARD1-dependent phosphoglycerate kinase 1 (PGK1) K388 acetylation and su

153 cible in vivo photofootprinting of the human phosphoglycerate kinase 1 (PGK1) promoter, as well as pr

154 at NogoA-overexpressing muscle cells reduced phosphoglycerate kinase 1 (Pgk1) secretion, resulting in

155 Of note, expressions of Phosphoglycerate Kinase 1 (PGK1), Hexokinase 2 (HK2), an

156 ssion and secretion of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1).

157 trate here that PTEN directly interacts with phosphoglycerate kinase 1 (PGK1).

158 V600E induce mitochondrial translocation of phosphoglycerate kinase 1 (PGK1); this is mediated by ER

159 ay genes, glucose transporter 1-4 (Glut1-4), phosphoglycerate kinase 1 and Glucokinase but not of pro

160 Elevated levels of phosphoglycerate kinase 1 in the serum were also signifi

161 Among these candidates, phosphoglycerate kinase 1 was associated with survival i

162 d that two of these proteins, annexin A5 and phosphoglycerate kinase 1, can bind directly with LPA.

163 endothelial growth factor (VEGF), Glut1, and phosphoglycerate kinase 1, increased in the Cited2(-/-)

164 Phosphoglycerate kinase 2 (PGK2) is a germ cell-specific

165 ontaining the known, translationally delayed phosphoglycerate kinase 2 (Pgk2) is initially transcribe

166 1 mutant exhibited very low but measurable 3-phosphoglycerate kinase activity compared to the wild-ty

167 triphosphate inhibited recombinant T. brucei phosphoglycerate kinase activity in vitro with an IC50 o

168 s illustrated using the N-terminal domain of phosphoglycerate kinase and a synthetic reagent containi

169 ump-induced refolding of two proteins, yeast phosphoglycerate kinase and a ubiquitin mutant.

170 e (glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase and fructose bisphosphate aldola

171 ubation with bulk ATP or by operation of the phosphoglycerate kinase and pyruvate kinase reactions to

172 teomics and stimulation analyses, identified phosphoglycerate kinase as a stimulatory factor for neut

173 ilibrium dynamics of the native state, using phosphoglycerate kinase as model protein.

174 Using yeast phosphoglycerate kinase as model, here we identify the f

175 urant-induced unfolding transitions of yeast phosphoglycerate kinase by mapping several inter- and in

176 Apomyoglobin denaturant unfolding and phosphoglycerate kinase cold denaturation are discussed

177 ompare the folding kinetics of a fluorescent phosphoglycerate kinase construct in 30 mammalian cells

178 sonance energy transfer (FRET) probe-labeled phosphoglycerate kinase construct in two human cell line

179 The two protein domains of phosphoglycerate kinase correspond to two dynamic units,

180 mine whether this was caused by the retained phosphoglycerate kinase I gene promoter (PGK-neo) casset

181 itro, even though translational diffusion of phosphoglycerate kinase in the cell is slow compared to

182 gen, we propose that plasmin ligands such as phosphoglycerate kinase induce a conformational change i

183 Decrease in the expression of 3-phosphoglycerate kinase led to a corresponding decrease

184 reductase, UDP-glucose pyrophosphorylase and phosphoglycerate kinase play a role in heat-stress-media

185 hemical shift and hydrogen exchange rates as phosphoglycerate kinase progresses through its catalytic

186 ice that overexpress CXCL14 under control of phosphoglycerate kinase promoter.

187 he control of a strong internal constitutive phosphoglycerate kinase promoter.

188 primary spermatocytes to provide a source of phosphoglycerate kinase that is critical to normal motil

189 ed that protein disulfide isomerase-like and phosphoglycerate kinase were required for optimal SCMV r

190 e mesoscopic level, including the pig muscle phosphoglycerate kinase with 416 residues.

191 acetyl-CoA carboxylase) and Pgk-1 (plastid 3-phosphoglycerate kinase) genes to determine phylogenetic

192 the stability of the cytoplasmic enzyme PGK (phosphoglycerate kinase) increases in cells, the stabili

193 s in lentiviral vectors (cytomegalovirus and phosphoglycerate kinase) revealed that suppression of vi

194 We studied the role of 3-phosphoglycerate kinase, a glycolytic enzyme, in the met

195 gene expression compared with MLV, MSV LTR, phosphoglycerate kinase, and CMV promoters in T-cell lin

196 e, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, and enolase were elevated.

197 f HIF-1alpha target genes, such as for VEGF, phosphoglycerate kinase, and glucose transporter-1.

198 Therefore, roles of creatine kinase, 3-phosphoglycerate kinase, and pyruvate kinase were evalua

199 on, which mapped to pgk, the gene encoding 3-phosphoglycerate kinase, failed to suppress a resD mutat

200 cular-dynamics (MD) simulation of a protein, phosphoglycerate kinase, from which we calculate small-a

201 atments were identified as adenylate kinase, phosphoglycerate kinase, glyceraldehyde-3-phosphate dehy

202 For the N-terminal domain of phosphoglycerate kinase, hen egg-white lysozyme and BPTI

203 nactivation center XIST and the ATRX, ATP7A, phosphoglycerate kinase, POU3F4, and choroideremia genes

204 sphates were selectively phosphorylated by 3-phosphoglycerate kinase, whereas, D-deoxynucleoside anal

205 we show that disrupting the glycolytic gene phosphoglycerate kinase-1 (pgk1) impairs Fgf-dependent d

206 Here, we used a ubiquitously active phosphoglycerate kinase-1 promoter to drive the expressi

207 led shRNA upon removal of a floxed reporter (phosphoglycerate kinase-driven enhanced green fluorescen

208 n sites around exon 7 of the Gbe1 gene and a phosphoglycerate kinase-Neomycin cassette within intron

209 and promoter region of the IRBP gene with a phosphoglycerate kinase-promoted neomycin-resistant gene

210 G binding site and in the hinge regions of 3-phosphoglycerate kinase.

211 ting glycolysis, especially by inhibition of phosphoglycerate kinase.

212 n of 1,3-bisphosphoglycerate, a substrate of phosphoglycerate kinase.

213 and the glycolytic phosphotransfer enzyme, 3-phosphoglycerate kinase.

214 es to regulation of 3-phosphoglycerate and 2-phosphoglycerate levels, promoting cancer cell prolifera

215 rprisingly, each dimer is comprised of one 3-phosphoglycerate.MgADP.PGK ternary complex and one Pi.Mg

216 osphonates bind in a manner similar to the 3-phosphoglycerate molecule identified crystallographicall

217 The more active was C16-phosphoglycerate-MurNAc-(L-Ala-D-Glu)-GlcNAc, which also

218 cture of Escherichia coli cofactor-dependent phosphoglycerate mutase (dPGM), complexed with the poten

219 (TroR), and the essential glycolytic enzyme phosphoglycerate mutase (Gpm).

220 ween the 2, 3-diphosphoglycerate-independent phosphoglycerate mutase (iPGM) from Bacillus stearotherm

221 of Leishmania mexicana cofactor-independent phosphoglycerate mutase (Lm iPGAM) crystallised with the

222 double labelled (15N,13C) monomeric, 23.7 kD phosphoglycerate mutase (PGAM) from Schizosaccharomyces

223 Here we report the interaction of Pak with phosphoglycerate mutase (PGAM)-B, an enzyme of the glyco

224 the phosphorylation of the glycolytic enzyme phosphoglycerate mutase (PGAM1) in PKM2-expressing cells

225 atase activity located within its C-terminal phosphoglycerate mutase (PGM) homology domain and key fo

226 the ecdysone phosphate phosphatase (EPPase) phosphoglycerate mutase (PGM) homology domain, the first

227 Bacillus stearothermophilus phosphoglycerate mutase (PGM), which interconverts 2- an

228 fibroblasts identified the glycolytic enzyme phosphoglycerate mutase (PGM).

229 Phosphoglycerate mutase 1 (PGAM1) functions in glycolysi

230 recently reported that the glycolytic enzyme phosphoglycerate mutase 1 (PGAM1) regulates anabolic bio

231 We found that the glycolytic enzyme phosphoglycerate mutase 1 (PGAM1), commonly upregulated

232 rs, covalently labeled the glycolytic enzyme phosphoglycerate mutase 1 (PGAM1), resulting in enzyme i

233 nts an additional acute mechanism underlying phosphoglycerate mutase 1 upregulation.

234 yaluronan synthase 2) and Bevacizumab/PGAM1 (Phosphoglycerate mutase 1) are interactions found in thi

235 The proteins phosphoglycerate mutase 2 (P. squamosissimus), hemoglobi

236 nd filamin-C), glycolytic enzymes (aldolase, phosphoglycerate mutase 2, beta enolase and glycogen pho

237 0 MPa) provoked a significant degradation of phosphoglycerate mutase 2, glycogen phosphorylase muscle

238 to extend Drosophila lifespan, and identify Phosphoglycerate Mutase 5 (PGAM5) as a mediator of this

239 Phosphoglycerate mutase 5 (PGAM5) is an atypical mitocho

240 activation of the mitochondrial phosphatase phosphoglycerate mutase 5 (PGAM5).

241 lysis and recombinant enzymes showed typical phosphoglycerate mutase activities in both the glycolyti

242 We provide evidence that phosphoglycerate mutase and enolase form a substrate-cha

243 New allergenic candidates, phosphoglycerate mutase and phosphoglucomutase, were ide

244 rtially associated with the axoneme, whereas phosphoglycerate mutase and pyruvate kinase primarily re

245 otide ubiquinone oxidoreductase chain 2, and phosphoglycerate mutase B], ion regulation (members of s

246 The C-terminal phosphoglycerate mutase domain of PGAM5 shares homology

247 Here we show that phosphoglycerate mutase family 5 (PGAM5) functions as a

248 ere, we present evidence that members of the phosphoglycerate mutase family 5 (PGAM5) proteins are in

249 ed mixed lineage kinase-like protein (MLKL), phosphoglycerate mutase family 5 (PGAM5), dynamin-relate

250 e demonstrate that the mitochondrial protein phosphoglycerate mutase family member 5 (PGAM5) is impor

251 her found that the mitochondrial phosphatase phosphoglycerate mutase family member 5 (PGAM5), a putat

252 ice deficient for the mitochondrial protein, phosphoglycerate mutase family member 5 (PGAM5), display

253 alytic domains found in other members of the phosphoglycerate mutase family, including a conserved hi

254 is report we have identified a member of the phosphoglycerate mutase family, PGAM5, as a novel substr

255 present at the active site of the monomeric phosphoglycerate mutase from the fission yeast Schizosac

256 new crystal form of Saccharomyces cerevisiae phosphoglycerate mutase has been solved and refined to 2

257 to investigate the influence of crowding on phosphoglycerate mutase in Escherichia coli, which exhib

258 des, unlike vertebrates, utilize independent phosphoglycerate mutase in glycolytic and gluconeogenic

259 Knockout mutation of phosphoglycerate mutase or enolase resulted in a signifi

260 ogenase (GPDH), calcium-binding protein, and phosphoglycerate mutase were also identified.

261 mer-specific autophosphorylation of NME1 and phosphoglycerate mutase were used with immunoblotting an

262 lycolysis (glucose-6-phosphate isomerase and phosphoglycerate mutase), in trehalose-6-P metabolism (t

263 Five of these (phosphoglycerate mutase, alcohol dehydrogenase, thioredo

264 etal transport system, the glycolytic enzyme phosphoglycerate mutase, and TroR.

265 three steps of the lower half of glycolysis (phosphoglycerate mutase, enolase, and pyruvate kinase).

266 lis, Treponema pallidum, the gene encoding 3-phosphoglycerate mutase, gpm, is part of a six-gene oper

267 Here, we reveal that the glycolytic enzyme phosphoglycerate mutase-1 (PGAM1) is negatively regulate

268 lism by overexpressing the glycolytic enzyme phosphoglycerate mutase-1 severely impaired the ability

269 The phosphoglycerate mutase-like domain of Sts-1 (Sts-1(PGM)

270 has been predicted to have only independent phosphoglycerate mutase.

271 with similarities to the catalytic motif of phosphoglycerate mutase.

272 ons with the glycolytic enzymes Aldolase and Phosphoglycerate mutase.

273 veals that it has homology to members of the phosphoglycerate mutase/acid phosphatase (PGM/AcP) famil

274 s similar to the group of cofactor-dependent phosphoglycerate mutase/bisphosphoglycerate mutase enzym

275 ilarity to 2, 3-diphosphoglycerate-dependent phosphoglycerate mutases (dPGM).

276 Phosphoglycerate mutases (PGMs) catalyze the isomerizati

277 Phosphoglycerate mutases catalyze the interconversion of

278 cloned and produced recombinant, independent phosphoglycerate mutases from C. elegans and the human-p

279 nzyme is neither activated by the effector 3-phosphoglycerate nor inhibited by P(i).

280 31P resonances of enzyme-bound substrates 2-phosphoglycerate (PGA) and phosphoenolpyruvate (PEP) wer

281 nt of the 2,3-diphosphoglycerate-independent phosphoglycerate (PGA) mutases [iPGMs].

282 dihydroxyacetone phosphate, a decrease in 3-phosphoglycerate, phosphoenolpyruvate, and pyruvate, and

283 er the apparent affinity for the activator 3-phosphoglycerate, showing two types of apparent roles fo

284 oroplast malate valve and triose phosphate-3-phosphoglycerate shuttle are predicted to have important

285 ) from Bacillus stearothermophilus and its 3-phosphoglycerate substrate has recently been solved, and

286 We have focused on the glucosyl-3-phosphoglycerate synthase (GpgS), a "retaining" enzyme,

287 taining shell protein that may weakly bind 3-phosphoglycerate, the product of CO2 fixation.

288 , a glycolytic-cycle enzyme that catalyzes 2-phosphoglycerate to form phosphoenolpyruvate, which is a

289 played a shift in effector preference from 3-phosphoglycerate to fructose-6 phosphate or fructose-1,6

290 y is controlled by the ratio of activator, 3-phosphoglycerate to inhibitor, P(i).

291 , the data revealed no significant flux from phosphoglycerate to Ser and Gly but showed formation of

292 fic chloroplast transporters could provide 3-phosphoglycerate to the cytosol.

293 e for shunting the glycolytic intermediate 3-phosphoglycerate to the serine synthesis pathway.

294 In addition, the binding of substrate (3-phosphoglycerate) to wild-type, E93D and R120,121Q enzym

295 In the presence of phosphate, 3-phosphoglycerate was a mixed inhibitor with respect to b

296 olites, pyruvate, phosphoenolpyruvate, and 2-phosphoglycerate were elevated in cortical cells after t

297 glycan cortex, but adenine nucleotides and 3-phosphoglycerate were not.

298 ibulose 1,5-bisphosphate (RuBP), producing 3-phosphoglycerate which is then converted to sugars.

299 olytic pathway can bypass the formation of 3-phosphoglycerate, which is a precursor for serine biosyn

300 GAPDH catalyzes the formation of 1-arseno-3-phosphoglycerate, which is then extruded out of the cell

301 Lm iPGAM co-crystallised with the product 2-phosphoglycerate yields the same structure.