ライフサイエンスコーパス: phosphoglycerate dehydrogenase

1 te of the ACT-domain of the Escherichia coli phosphoglycerate dehydrogenase.

2 Phosphoglycerate Dehydrogenase 1 of the phosphorylated p

3 Inhibition of phosphoglycerate dehydrogenase, a rate-limiting enzyme i

4 xtracts of M. maripaludis were shown to have phosphoglycerate dehydrogenase and phosphoserine aminotr

5 mes in the serine synthesis pathway, such as phosphoglycerate dehydrogenase and phosphoserine aminotr

6 1 enhances the expression of the key enzymes phosphoglycerate dehydrogenase and phosphoserine aminotr

7 The inhibition of Escherichia coli d-3-phosphoglycerate dehydrogenase by l-serine is positively

8 strongest associations were observed for D-3-phosphoglycerate dehydrogenase (D-3PGDH), cysteine and g

9 etate methyltransferase deficiency and for 3-phosphoglycerated dehydrogenase deficiency appear promis

10 intenance of the purine metabolizing enzyme, phosphoglycerate dehydrogenase, during LPS plus ATP trea

11 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escher

12 D-3-Phosphoglycerate dehydrogenase (EC 1.1.1.95) from Escher

13 Phosphoglycerate dehydrogenases exist in at least three

14 resents a second structural motif of the D-3-phosphoglycerate dehydrogenase family, one that contains

15 The binding of L-serine to phosphoglycerate dehydrogenase from E. coli displays ele

16 d-3-Phosphoglycerate dehydrogenase from Escherichia coli con

17 d-3-Phosphoglycerate dehydrogenase from Escherichia coli is

18 D-3-Phosphoglycerate dehydrogenase from Escherichia coli is

19 The heterologously expressed and purified phosphoglycerate dehydrogenase from M. maripaludis had e

20 D-3-Phosphoglycerate dehydrogenase from Mycobacterium tuberc

21 The crystal structure of D-3-phosphoglycerate dehydrogenase from Mycobacterium tuberc

22 structure of Mycobacterium tuberculosis d-3-phosphoglycerate dehydrogenase has been solved with boun

23 10 interacted with the chloroplastic protein phosphoglycerate dehydrogenase in a yeast (Saccharomyces

24 3-Phosphoglycerate dehydrogenase is an exclusively astrocy

25 that predicts that catalytic activity in D-3-phosphoglycerate dehydrogenase is regulated by the movem

26 tarate, facilitated by increased activity of phosphoglycerate dehydrogenase, leads to epigenetic alte

27 D-3-Phosphoglycerate dehydrogenase (PGDH) (EC 1.1.1.95) from

28 e catalytic activity of Escherichia coli D-3-phosphoglycerate dehydrogenase (PGDH) by binding to its

29 Phosphoglycerate dehydrogenase (PGDH) catalyzes the firs

30 Escherichia coli 3-phosphoglycerate dehydrogenase (PGDH) catalyzes the firs

31 An active conformation of phosphoglycerate dehydrogenase (PGDH) from Escherichia c

32 D-3-Phosphoglycerate dehydrogenase (PGDH) from Escherichia c

33 ructural homology with the ASB domain of d-3-phosphoglycerate dehydrogenase (PGDH) from Mycobacterium

34 D-3-Phosphoglycerate dehydrogenase (PGDH) from Mycobacterium

35 ric hybrid tetramers of Escherichia coli d-3-phosphoglycerate dehydrogenase (PGDH) have been made by

36 topped-flow analysis of Escherichia coli d-3-phosphoglycerate dehydrogenase (PGDH) reveals that the p

37 ding for the first enzyme of this pathway, 3-phosphoglycerate dehydrogenase (PGDH).

38 ol coefficient for the branch point enzyme 3-phosphoglycerate dehydrogenase (PGDH).

39 ulatory and substrate binding domains of D-3-phosphoglycerate dehydrogenase (PGDH, EC 1.1.1.95) from

40 e, we present a detailed characterization of phosphoglycerate dehydrogenases (PGDHs) as components of

41 with the ASB domain like that in type 1 D-3-phosphoglycerate dehydrogenases (PGDHs).

42 Individual gene effects were notable for phosphoglycerate dehydrogenase (PGHDH), peptidyl-prolyl

43 nately regulate expression of genes encoding phosphoglycerate dehydrogenase (PHGDH) and five downstre

44 Enzymes of the SSP, such as phosphoglycerate dehydrogenase (PHGDH) and phosphoserine

45 anically, NAT10 promotes the expression of 3-phosphoglycerate dehydrogenase (PHGDH) and phosphoserine

46 Phosphoglycerate dehydrogenase (PHGDH) catalyzes the fir

47 Astrocytes express the 3-phosphoglycerate dehydrogenase (Phgdh) enzyme required f

48 lycolysis to serine biosynthesis by inducing phosphoglycerate dehydrogenase (PHGDH) expression.

49 EVs, leading to a paracrine upregulation of phosphoglycerate dehydrogenase (PHGDH) in monocytes when

50 Among the genes identified, phosphoglycerate dehydrogenase (PHGDH) is in a genomic r

51 Phosphoglycerate dehydrogenase (PHGDH) is the metabolic

52 ction of circulating serine by inhibition of phosphoglycerate dehydrogenase (PHGDH) leads to the accu

53 hat altered expression of the LOAD biomarker phosphoglycerate dehydrogenase (PHGDH) modulates AD path

54 Here we find that the loss of phosphoglycerate dehydrogenase (PHGDH) potentiates metas

55 BA, but not GH, caused a 2-fold increase in phosphoglycerate dehydrogenase (PHGDH) protein expressio

56 nificance with multiple testing adjustments, phosphoglycerate dehydrogenase (PHGDH) was the only gene

57 mes of the de novo serine synthesis pathway (phosphoglycerate dehydrogenase (PHGDH), phosphoserine am

58 acid generated by the sequential actions of phosphoglycerate dehydrogenase (PHGDH), phosphoserine am

59 Inhibition of phosphoglycerate dehydrogenase (PHGDH), the first and ra

60 Phosphoglycerate dehydrogenase (PHGDH), the first rate-l

61 uman cancers often exhibit overexpression of phosphoglycerate dehydrogenase (PHGDH), the metabolic en

62 0) show that MEKi-resistant cells upregulate phosphoglycerate dehydrogenase (PHGDH), the rate-limitin

63 etween lipid metabolism and ERneg BC through phosphoglycerate dehydrogenase (PHGDH), the rate-limitin

64 Overexpression of phosphoglycerate dehydrogenase (PHGDH), the rate-limitin

65 The gene encoding the enzyme 3-phosphoglycerate dehydrogenase (PHGDH), which catalyzes

66 4 (ATF4) and its downstream effector genes, phosphoglycerate dehydrogenase (PHGDH), which encodes a

67 d into serine and glycine metabolism through phosphoglycerate dehydrogenase (PHGDH).

68 s activity of the serine biosynthesis enzyme phosphoglycerate dehydrogenase (PHGDH).

69 Macular Muller cells expressed more phosphoglycerate dehydrogenase (PHGDH, a rate-limiting e

70 d-3-Phosphoglycerate dehydrogenase (Phgdh; EC 1.1.1.95) is t

71 d genes associated with serine biosynthesis (Phosphoglycerate dehydrogenase, Phgdh; phosphoserine ami

72 of residues in the regulatory domains of D-3-phosphoglycerate dehydrogenase provide the first direct

73 The crystal structure of d-3-phosphoglycerate dehydrogenase reveals a limited number

74 The first D-3-phosphoglycerate dehydrogenase structure to be determine

75 In Escherichia colid-3-phosphoglycerate dehydrogenase, the amino acid sequences

76 n part to the genomic copy number gain for 3-phosphoglycerate dehydrogenase, the enzyme that controls

77 Consistently, inhibition of phosphoglycerate dehydrogenase, the first enzyme of the

78 sphate pathway (PPP), while 2-PG activates 3-phosphoglycerate dehydrogenase to provide feedback contr

79 ns indirectly enhance the ability of SerA (3-phosphoglycerate dehydrogenase) to perform a new functio

80 Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase undergoes significant inh

81 topped flow analysis of Escherichia coli D-3-phosphoglycerate dehydrogenase was performed by followin

82 and mice with targeted deletion of Srr or 3-Phosphoglycerate dehydrogenase, we demonstrate predomina

83 Strains lacking yggS and serA (3-phosphoglycerate dehydrogenase) were conditionally letha

84 same fold; (iii) the C-terminal domain of 3-phosphoglycerate dehydrogenase, which binds serine and i

85 e structure of a truncated form of human d-3-phosphoglycerate dehydrogenase with cofactor and a subst