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1 2 membrane phospholipids phosphodiester and phosphomonoester.
2 cNAc(2) oligosaccharides containing a single phosphomonoester.
3 n atom, forming thiirane with departure of a phosphomonoester.
4 underscoring the specific requirement for a phosphomonoester.
5 des to a C(3v) symmetric scaffold that binds phosphomonoesters.
6 at used by protein phosphatases to hydrolyze phosphomonoesters.
7 hydrolytic activity was readily inhibited by phosphomonoesters.
8 lase) was obtained from this and changes in [phosphomonoester].
9 Alkaline or enzymic hydrolysis of 5a gave phosphomonoester alaninate 14, a putative product of int
12 by intracellular esterase(s) to give stable phosphomonoester amidate intermediates with a free carbo
13 sm of aromatic amino acid carbomethoxy ester phosphomonoester amidate nucleotide prodrugs by PBMCs do
14 hate, formed in PBMCs incubated with the AZT phosphomonoester amidates 3 and 4 was 2- and 3-fold less
17 mphocytes, the amino acid carbomethoxy ester phosphomonoester amidates of AZT are not significantly m
18 studies on the amino acid carbomethoxy ester phosphomonoester amidates revealed that their decomposit
22 catalyzes both the nonspecific hydrolysis of phosphomonoesters and a transphosphorylation reaction in
25 hiourea N-riboside, ensuing installment of a phosphomonoester at the 5'-hydroxyl of the ribosyl moiet
28 higher than degradation of ATP and the model phosphomonoester compound 4-methylumbelliferyl phosphate
29 sphodiester derivatives, but strongly to the phosphomonoester-containing glycans with the exception o
30 to soluble carbohydrate ligands (i.e., PPME, phosphomonoester core polysaccharide) and to lymph node
31 nd-order rate constant for hydrolysis of the phosphomonoester dianion is enhanced approximately 2 x 1
32 ilitated product release, in which the Ser33 phosphomonoester forms a salt bridge with the Arg95 guan
33 H 7-9.5) was governed by the position of the phosphomonoester group at the inositol ring (PI-4P > PI-
35 sphate is found downfield from the other two phosphomonoester group peaks, an increase in pH leads to
36 n the basis of the ability of the respective phosphomonoester group to form intramolecular hydrogen b
37 idylinositol 3,5-bisphosphate, where the two phosphomonoester groups are separated by a hydroxyl grou
39 rge of the phosphatidylinositol bisphosphate phosphomonoester groups, leading to an overall charge of
43 pports the in-line displacement mechanism of phosphomonoester hydrolysis by alkaline phosphatase and
44 f substrate leaving group pKa indicated that phosphomonoester hydrolysis is rate-limiting at pH 7.0,
46 show that DNA can catalyze Zn(2+)-dependent phosphomonoester hydrolysis of tyrosine and serine side
49 ss of membrane signaling lipids that contain phosphomonoesters in their headgroups having pK(a) value
50 revealed increases in the choline/water and phosphomonoester (including PC)/total phosphate ratios i
51 bolite concentration changes associated with phosphomonoesters, inorganic phosphate, gamma-nucleotide
52 e, we show that PafA is highly active toward phosphomonoesters, is fully functional in the presence o
53 ransduced tumors in vivo showed lower PC and phosphomonoester levels that were associated with reduce
54 ad peak, which is consistent with P bound by phosphomonoester linkages of supra-/macro-molecular stru
55 ous ligands for the MPRs that contain solely phosphomonoesters (Man-6-P) or phosphodiesters (mannose
56 crease in phosphocholine, total choline, and phosphomonoesters may have potential as noninvasive phar
58 ant concentration-dependent shift of the two phosphomonoester peaks, suggesting that PI(4,5)P(2) is c
59 s free energy of ATP hydrolysis (DeltaGATP), phosphomonoesters, phosphodiesters, pH, free magnesium c
60 phosphate (Pi)] and membrane phospholipids [phosphomonoesters/phosphodiesters (PME/PDE)] in 216 midl
61 ic increase in the mean +/- 1 standard error phosphomonoester (PME) to phosphodiester (PDE) ratios fo
62 /- 1.3% versus 3.9 +/- 0.7%, p = 0.0001) and phosphomonoesters (PMEs) (9.4 +/- 1.2% versus 6.9 +/- 0.
63 (31)P MR peak area ratios of signals from phosphomonoesters (PMEs), inorganic phosphate (P(i)), ph
66 marine flavobacteria, rapidly remineralizes phosphomonoesters releasing bioavailable phosphate that
67 r two Man-P-GlcNAc phosphodiester or Man-6-P phosphomonoester residues was determined by analysis on
69 e N15A and S19A mutants were performed using phosphomonoester substrates with varied phenolic leaving
70 itiated calcification by intact MVs, whereas phosphomonoesters such as beta-glycerophosphate or phosp
71 that has a substantially higher affinity for phosphomonoesters than other well-known phosphatases lik
72 ane phospholipid (MPL) precursor levels (ie, phosphomonoesters that are anabolic metabolites of MPL)
75 ratio, inorganic phosphate to ATP ratio, and phosphomonoester to ATP ratio were not substantially alt
76 lyze the transfer of a phosphoryl group from phosphomonoesters to water at acidic pH using an active-
77 s where resting inorganic phosphate, pH, and phosphomonoesters were increased, whereas resting DeltaG
78 oxyguanosine nucleotide phosphoramidates and phosphomonoesters were synthesized in high conversion yi