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1 ioate, which in turn is more stable than the phosphorodithioate.
2 phosphate, (2) [Rp]-phosphorothioate, or (3) phosphorodithioate.
3  in the mechanism for the S(p) isomer of the phosphorodithioate analogue into a more dissociative typ
4 e we present the synthesis of dithio-CN03, a phosphorodithioate analogue of cGMP, prepared using the
5 products of cleavage of phosphorothioate and phosphorodithioate analogues of PI in which sulfur was i
6 trations, an oligomer containing alternating phosphorodithioate and phosphate linkages was able to di
7             Oligomers containing alternating phosphorodithioate and phosphate were highly resistant t
8 ree of Tm depression paralleling the percent phosphorodithioate composition of the oligomer.
9                  These results indicate that phosphorodithioate-containing DNA oligomers are highly n
10                   The nuclease resistance of phosphorodithioate-containing oligomers was evaluated in
11 ide leading to the quantitative formation of phosphorodithioate diesters uncontaminated with the corr
12  method for the synthesis of deoxynucleoside phosphorodithioate dimers is described.
13 igh-resolution separation of oligonucleotide phosphorodithioates from monothiophosphate impurities wa
14 ion conditions, a hammerhead ribozyme with a phosphorodithioate linkage at the cleavage site cleaved
15                                          The phosphorodithioate linkage is introduced using a new dit
16 tides containing a site-specific nonbridging phosphorodithioate linkage via automated solid-phase syn
17 onucleotides containing a high percentage of phosphorodithioate linkages in lower salt concentrations
18 mical properties of DNA oligomers containing phosphorodithioate linkages in various configurations we
19  RNase H, DNA oligomers containing up to 50% phosphorodithioate linkages were able to direct RNase H
20 gurations containing phosphoromonothioate or phosphorodithioate linkages were evaluated for antisense
21                         Oligomers containing phosphorodithioate linkages were found to have reduced m
22 eins specifically binding to oligonucleoside phosphorodithioate (ODN) aptamers from a bead-bound ODN
23 hosphorothioate oligonucleotides (S-ODNs) or phosphorodithioate oligonucleotides (S2-ODNs) with sulfu
24 2))T(PO(2))](7)T, which contains alternating phosphorodithioate/phosphate diester internucleotide lin
25 c)-PS with native phosphodiester (PO(2)) and phosphorodithioate (PS(2)) linkages into DNA and other m
26 eport a chemical modification, consisting of phosphorodithioate (PS2) and 2'-O-Methyl (2'-OMe) MePS2
27                We report here the use of the phosphorodithioate (PS2) substitution on a single nucleo
28 when the hybrids contain phosphorothioate or phosphorodithioate substitutions.
29  more than one unmodified linkage separating phosphorodithioates were degraded rapidly by DNase I, wh