ライフサイエンスコーパス: phosphorylation activity

1 activator alone and engenders dominant mono-phosphorylation activity.

2 phosphorylation is necessary for JIL-1 H3S10 phosphorylation activity.

3 tly marked PC12 cells with sustained protein phosphorylation activity.

4 rturbation of this interface leads to higher phosphorylation activity.

5 tly increases RICK/NOD1 association and RICK phosphorylation activity.

6 re, HSV1-tk(A168H) demonstrated no thymidine phosphorylation activity.

7 of activity and also retained some oxidative phosphorylation activity.

8 nces while TSPX represses the cyclin B1-CDK1 phosphorylation activity.

9 modulates glucose metabolism mainly by AMPKa phosphorylation activity.

10 family PTKs were required for this tyrosine phosphorylation activity.

11 d M. tuberculosis PknD KD fusions stimulated phosphorylation activity.

12 letely absent from compartments with Ser-473 phosphorylation activity.

13 nnels, and Ca(2+)-independent, involving MLC phosphorylation activity.

14 modeled to accommodate a change in oxidative phosphorylation activity.

15 lation (<5%) but retained near-wild-type H2B phosphorylation activity.

16 finity for aspartate is linked to changes in phosphorylation activity.

17 on, implying diminished glucose transport or phosphorylation activity.

18 ng decreased muscle glucose transport and/or phosphorylation activity.

19 due to a defect in glucose transport and/or phosphorylation activity.

20 lls demonstrated a 20-30% decrease in DNA-PK phosphorylation activity.

21 with another PTK, ZAP70, and stimulates its phosphorylation activity.

22 tion to aspartic or glutamic acids abolished phosphorylation activity.

23 y 2-3-fold weaker protein kinase C substrate phosphorylation activity.

24 by sequentially regulating FAK and paxillin phosphorylation/activity.

25 hearts and was accompanied by increased Akt phosphorylation/activity.

26 hesis distinct from that regulating the MtrA phosphorylation activities.

27 autophosphorylation and Myelin Basis Protein phosphorylation activities.

28 otein kinase C (PKC), and constitutive MYPT1 phosphorylation activities.

29 o blockade of protein kinase Mzeta (PKMzeta) phosphorylation activity, a manipulation that reverses h

30 ls for Rheb reveal reciprocal changes in PDH phosphorylation/activity, acetyl-CoA, and ATP that are n

31 , inhibited selectively this surface protein phosphorylation activity and blocked the stabilization o

32 Hexokinase-Like1 (HKL1) lacks glucose (Glc) phosphorylation activity and has been shown to act as a

33 erms of both autophosphorylation and histone phosphorylation activity and induces the same in vivo ph

34 -sequencing analysis indicate that oxidative phosphorylation activity and inhibition of meiotic initi

35 ted both phosphoenolpyruvate-dependent sugar phosphorylation activity and sugar phosphate-dependent s

36 l effects were associated with preserved Akt phosphorylation/activity and attenuation of DOX-induced

37 eron-stimulated genes, stimulating oxidative phosphorylation activity, and increasing reactive oxygen

38 metastatic melanoma cells by inhibiting CREB phosphorylation, activity, and binding to the MUC18 prom

39 n-dependent decrease in constitutive ERK-1/2 phosphorylation, activity, and nuclear localization that

40 ation-dependent loss of constitutive Erk-1/2 phosphorylation, activity, and nuclear localization.

41 ns of PKC consensus sites reduced Pcyt2alpha phosphorylation, activity, and phosphatidylethanolamine

42 imer's disease is related to reduced glucose phosphorylation activity as well as diminished glucose t

43 40% reduction in mitochondrial oxidative and phosphorylation activity, as assessed by in vivo 13C/31P

44 endogenous CK1 was the major source of basal phosphorylation activity at these sites.

45 y differences in other areas associated with phosphorylation activity between wild-type and mutant Ka

46 , which retains autophosphorylation and ResD phosphorylation activities but is defective in ResD deph

47 9 to Met or Leu resulted in mutants that had phosphorylation activity but displayed greatly decreased

48 e established that mutation in A368S reduces phosphorylation activity by 40%; A41E mutation completel

49 rted an important role of increased tyrosine phosphorylation activity by Src in the modulation of hyp

50 3 sustained altered glycolytic and oxidative phosphorylation activities characteristic of cancer cell

51 bular networks in vitro showed that tyrosine phosphorylation activity colocalized specifically within

52 out the NH2-terminal domain is without H3S10 phosphorylation activity despite the fact that it locali

53 g human thymidine kinase exhibited thymidine phosphorylation activity equivalent to approximately 5%

54 skeletal function, ERK2 signaling (e.g. ERK2 phosphorylation/activity, ERK2-mediated Elk-1/ER alpha p

55 Ysr39tk, which exhibits specificity and high phosphorylation activity for acycloguanosine derivatives

56 basal versus RNA-stimulated C1 hnRNP protein phosphorylation activities from nuclear extracts.

57 Although the (auto)phosphorylation activity has been shown to be essential

58 mics, test tube kinetic assays of downstream phosphorylation activity, high-throughput bacteriophage-

59 as affinity ligand, showed higher histone H1 phosphorylation activity in AD.

60 assess the rates of mitochondrial oxidative-phosphorylation activity in muscle.

61 ciated reductions in mitochondrial oxidative phosphorylation activity in skeletal muscle as a predisp

62 reased ATP synthase expression and oxidative phosphorylation activity in TAMs located in the tumor co

63 gression and decreased whole-brain oxidative phosphorylation activity in the honey bee (Apis mellifer

64 CheY in the reverse direction by quantifying phosphorylation activity in the presence and absence of

65 Surprisingly, P-TEFb exhibits Ser5 phosphorylation activity in vitro.

66 rmore, we show that the continuous oxidative phosphorylation activity is important for viral propagat

67 8 or R1590 of Fhod3 is methylated then ROCK1 phosphorylation activity is only slightly affected.

68 Upon pathogen infection, ZmWAKL(Y) phosphorylation activity is transiently increased, initi

69 l receptor for IgE, and colocalized tyrosine phosphorylation activity, Lyn kinase and other proteins

70 hromatin structure and where catalytic H3S10 phosphorylation activity mediated by the first kinase do

71 Using the streptavidin capture assay the phosphorylation activities of recombinant IKK-1 and -2 w

72 autoregulated transcription but demands high phosphorylation activities of TCS proteins.

73 and Chk1 leads to an increase in the Cdc25C phosphorylation activity of Chk1.

74 between the c-KIT kinases by modulating the phosphorylation activity of each in a distinct mechanism

75 in a conserved lysine residue important for phosphorylation activity of kinases (K118E) failed to co

76 chemical depalmitoylation reduces the casein phosphorylation activity of the palmitoylated, but not p

77 We have applied our method to measuring the phosphorylation activity of the Wee1 and Myt1 kinases.

78 Reciprocal modulation of the phosphorylation (activity) of two isoforms within the sa

79 SETD2 deficiency boosts oxidative phosphorylation activity, prompting lipid-laden CAF form

80 Disruption of TRPM6 kinase phosphorylation activity re-introduces Mg.ATP sensitivit

81 lt in stimulation of mitochondrial oxidative phosphorylation activity, restore physiologic mitochondr

82 eal a delicate balance of ubiquitination and phosphorylation activities that alter the gene regulator

83 ssociated MAPK operates through constitutive phosphorylation activity to regulate microtubule functio

84 in vitro and also by comparing the relative phosphorylation activity toward a panel of peptide subst

85 Recombinant RLPK possesses high phosphorylation activity toward histone 2B and the S6 pe

86 This phosphorylation activity was detected on the surface of

87 ' LacI-JIL-1 construct without histone H3S10 phosphorylation activity was expressed.

88 Furthermore, RICK phosphorylation activity was increased when NOD was preb

89 This increased phosphorylation/activity was accompanied by up-regulatio

90 PTP opening, whereas mitochondrial oxidative phosphorylation activities were not affected.

91 ll VZVTK mutants tested retained significant phosphorylation activity with dThd as substrate, apart f