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1 g pKa values of 5.6 (phosphoserine) and 5.9 (phosphothreonine).
2 tified 32P-Tyr, [32P]phosphoserine, and [32P]phosphothreonine.
3 ree P-Tyr (5 mM) but not by phosphoserine or phosphothreonine.
4  residue but did not cleave phosphoserine or phosphothreonine.
5 strates because B55 displays selectivity for phosphothreonine.
6  many but not all cases specifies binding to phosphothreonine.
7 zen polypeptides, several of which contained phosphothreonine.
8 dition of phosphotyrosine, phosphoserine, or phosphothreonine.
9  and PH domains, respectively, bind ICP10 at phosphothreonines 117 and 141 and a WD40-like motif at p
10      MLCP dephosphorylated phosphoserine 19, phosphothreonine 18, and phosphothreonine 9 efficiently
11                                      Using a phosphothreonine 187 site-specific antibody for p27, we
12 ing an antibody that specifically recognizes phosphothreonine-231) and T-tau using ultra-high sensiti
13                                 By detecting phosphothreonine 388 of mosquito S6 kinase, we show that
14 th fetal bovine serum markedly increased the phosphothreonine 410 content of CAT zeta and stimulated
15                                            A phosphothreonine 423-specific antibody detected phosphor
16           PPM1D dephosphorylation of UNG2 at phosphothreonine 6 is associated with reduced UNG2 activ
17         We hypothesized that the presence of phosphothreonine 753 either renders beta(3) a poor subst
18 d phosphoserine 19, phosphothreonine 18, and phosphothreonine 9 efficiently with almost identical rat
19    Dianionic phosphothreonine induced strong phosphothreonine amide protection and downfield amide ch
20       Forkhead-associated (FHA) domains bind phosphothreonine and control many aspects of cell prolif
21 ot discriminate between dephosphorylation of phosphothreonine and phosphoserine residues in synthetic
22 ytically active form of Cdc25A for efficient phosphothreonine and phosphotyrosine dephosphorylation.
23            The lip is refolded, bringing the phosphothreonine and phosphotyrosine into alignment with
24 ephosphorylate contiguous and semicontiguous phosphothreonine and phosphotyrosine on cyclin dependent
25 activation of the MAP kinases by hydrolyzing phosphothreonine and phosphotyrosine residues present in
26    Alpha-ZrPN also bound peptides containing phosphothreonine and phosphotyrosine.
27 es in immunoblotting with anti-phosphoserine/phosphothreonine antibodies.
28  solution Raman spectra of phosphoserine and phosphothreonine are assigned to the monobasic and dibas
29 sine, but did not hydrolyse phosphoserine or phosphothreonine at a measureable rate.
30                        While substitution of phosphothreonine at position 16 causes generally similar
31 nd unusual preference for phosphoserine over phosphothreonine at Pro-directed sites in vitro.
32 as a 14-3-3 interaction with a phosphoserine/phosphothreonine at the C-termini of the target protein.
33 due was identified that sterically restricts phosphothreonine binding and is largely responsible for
34 ks the structural properties associated with phosphothreonine binding and thus most likely interacts
35                            Phosphoserine- or phosphothreonine-binding activity was required for Pin1
36 d synchronously inactivate all phosphoserine/phosphothreonine-binding domain family members in a rapi
37 ytoplasmic regulatory module consisting of 2 phosphothreonine-binding Forkhead-associated domains joi
38  WW domain functioned as a phosphoserine- or phosphothreonine-binding module, with properties similar
39 e been well-characterized, phosphoserine- or phosphothreonine-binding modules have not been described
40 ysis of suppressors of a mutation in the Cdk phosphothreonine-binding pocket created by cyclin bindin
41 d Arg294 and Arg295 that likely comprise the phosphothreonine-binding pocket in PAC-1 to either alani
42 osphorylation by Clb2-Cdk1-Cks1 requires the phosphothreonine-binding site of Cks1, as well as a rece
43 N, inactivated Hog1 by dephosphorylating the phosphothreonine but not the phosphotyrosine residue in
44 racts are supershifted by phosphoserine- and phosphothreonine- but not phosphotyrosine-specific antib
45 ecreased phosphoserine by 80%, and decreased phosphothreonine by 70%.
46 ferred substrate, although phosphoserine and phosphothreonine can also be cleaved.
47 ited a comparable substrate preference for a phosphothreonine containing substrate, consistent with t
48 cognition motifs that specifically recognize phosphothreonine-containing epitopes.
49 ntation performs validation of phosphoserine/phosphothreonine-containing peptides having one or two p
50 inhibited Wip1 phosphatase activity, whereas phosphothreonine-containing peptides with the sequence p
51                 Phosphorylation of a 130-kDa phosphothreonine-containing protein (FP130) occurred thr
52                                   One of the phosphothreonine-containing proteins was identified by m
53               Because FHA domains respond to phosphothreonine-containing proteins, these results sugg
54 phatases that hydrolyze phosphotyrosine- and phosphothreonine-containing substrates.
55  Our observations suggest that phosphoserine/phosphothreonine-dependent localization is a key feature
56 achieving stereodivergence: peptide-embedded phosphothreonine-derived CPAs, which reinforce and ampli
57 2)-symmetric chiral phosphoric acids and (b) phosphothreonine-embedded, peptidic phosphoric acids.
58 horylation site contained a phosphoserine or phosphothreonine followed by a proline, suggesting that
59 In the accompanying paper, we identify three phosphothreonines important in this process.
60 tase 2A (PP2A) in vitro to dephosphorylate a phosphothreonine in a conserved TPNK sequence in the SLB
61       By combining a method to biosynthesize phosphothreonine in cells with this selection approach,
62 ion specificity of EYA1 in dephosphorylating phosphothreonine in Myc but also reveal an important mec
63  carbachol, leads to the rapid appearance of phosphothreonine in nonmuscle myosin heavy chain II-A (N
64 entirely biosynthetic route to incorporating phosphothreonine in proteins.
65             Glutamic acid can substitute for phosphothreonine in some proteins activated by phosphory
66 hat rWip1 dephosphorylates phosphoserine and phosphothreonine in the p(S/T)Q motif, which is an essen
67 eloped by measuring stable phosphoserine and phosphothreonine in vitro.
68                                    Dianionic phosphothreonine induced strong phosphothreonine amide p
69 ty for phosphotyrosine over phosphoserine or phosphothreonine is considerable, but the enzyme did not
70 exposed yet deep active site cleft while the phosphothreonine is loosely tethered into a nearby basic
71 ss spectrometry we demonstrate that SpvC has phosphothreonine lyase activity on full-length phospho-E
72 ated and that this modification inhibits its phosphothreonine lyase activity.
73               The newly discovered bacterial phosphothreonine lyases perform a post-translational mod
74                                    Bacterial phosphothreonine lyases, or phospholyases, catalyze a un
75 ue with a non-hydrolyzable the phosphoserine/phosphothreonine mimetic would promote binding to the 14
76 e diverse phosphoproteins, preferentially at phosphothreonine near acidic residues, near the protein
77 rylated by a kinase other than MEK1 and that phosphothreonines on Red1 then interact with the Mek1 FH
78 ne (Dhb) or dehydroalanine (Dha) in place of phosphothreonine or phosphoserine residues, respectively
79 s with hot spots specific for phosphoserine, phosphothreonine or phosphotyrosine.
80 blot analysis using anti-phosphoserine, anti-phosphothreonine, or anti-phosphotyrosine antibody to de
81 ily of Mg2+ -dependent phosphoserine (P.Ser)/phosphothreonine (P.Thr)-specific phosphatases.
82 agrees with that of KI-FHA in contact with a phosphothreonine peptide ligand.
83 ore modeled on natural product inhibitors of phosphothreonine phosphatases, we generated a refined li
84 E technologies for installing phosphoserine, phosphothreonine, phosphotyrosine, and their mimics, dis
85 Pin1 binds specifically to phosphoserine- or phosphothreonine-proline (pS/T-P) motifs in target prote
86 ally recognizes the phosphoserine-proline or phosphothreonine-proline bonds present in mitotic phosph
87 PP2Calpha is a metal-dependent phosphoserine/phosphothreonine protein phosphatase and is the represen
88                                        Using phosphothreonine, protein kinase A (PKA), and PKC substr
89 its no activity toward phosphoserine (pS) or phosphothreonine (pT) peptides.
90 yeast Rad53p, which is a naturally occurring phosphothreonine (pT)-binding domain, and found it to be
91 (Plk1) as a specific phosphoserine (pSer) or phosphothreonine (pThr) binding domain and determined it
92 iated (FHA) domains are modules that bind to phosphothreonine (pThr) residues in signaling cascades.
93                                              Phosphothreonine (pThr) was found to constitute a new cl
94 OL-derived chiral phosphoric acids (CPA) and phosphothreonine (pThr)-embedded peptides were found to
95 photyrosine alone (pY), or phosphotyrosine + phosphothreonine (pYT).
96 s mediated by an extended surface containing phosphothreonine recognition and hydrophobic interfaces
97 kinase A phosphorylation and the loss of the phosphothreonine residue and a major phosphopeptide that
98 f the enteropathogen Shigella to convert the phosphothreonine residue of the pT-X-pY consensus sequen
99 ally high pK values of the phosphoserine and phosphothreonine residues and the preference for a diani
100 PPPs) that dephosphorylate phosphoserine and phosphothreonine residues are increasingly understood as
101                            Phosphoserine and phosphothreonine residues exhibited ordered values of (3
102 mination of phosphate from phosphoserine and phosphothreonine residues followed by addition of an aff
103 l protein domains that bind phosphoserine or phosphothreonine residues have been identified, includin
104 phosphate moiety from both phosphoserine and phosphothreonine residues in low-energy collision-induce
105 sphorylates both the phosphotyrosine and the phosphothreonine residues in the activation loop of the
106 chemical transformation of phosphoserine and phosphothreonine residues into lysine analogs (aminoethy
107 h the dephosphorylation of phosphoserine and phosphothreonine residues of the cyclase receptor.
108 addition and conversion of phosphoserine and phosphothreonine residues to S-ethylcysteinyl or beta-me
109 ical derivatization of the phosphoserine and phosphothreonine residues using stable isotopic variants
110  values for the presence of phosphoserine or phosphothreonine residues using tandem mass spectrometry
111  in the production of both phosphoserine and phosphothreonine residues.
112  calorimetry, using peptides containing both phosphothreonine residues.
113  Nup species revealed only phosphoserine and phosphothreonine residues.
114 atase and dephosphorylates phosphoserine and phosphothreonine residues.
115  insert loop with multiple phosphoserine and phosphothreonine residues.
116      FHA domains in other proteins recognize phosphothreonine residues.
117 hosphorylating phosphotyrosine residues over phosphothreonine residues.
118 odies to O-linked GlcNAc, phosphoserine, and phosphothreonine showed that hyperglycemia increased Glc
119 ss-phosphorylating TRPM7 as assessed using a phosphothreonine-specific antibody but not vice versa.
120 g protein) and in BRCA1 as phosphoserine- or phosphothreonine-specific binding modules that recognize
121 T repeats in BRCA1 are phosphoserine- and/or phosphothreonine-specific binding modules.
122 CD0242 protein catalyses the addition of the phosphothreonine to the N-acetylglucosamine moiety and C
123 challenges by optimizing genetically encoded phosphothreonine translation to characterize phospho-dep
124                                              Phosphothreonine was detected within two TPVK motifs and
125                                  No Stat5a/b phosphothreonine was detected.
126 oncognate amino acids glutamate, serine, and phosphothreonine without the need for a separate hydroly

 
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