ライフサイエンスコーパス: photoactivate

1 e-red light, a condition in which OCP is not photoactivated.

2 ion of KRAS and NRAS expression, but only if photoactivated.

3 mbranes and displays weak fluorescence until photoactivated.

4 revious work has demonstrated the ability of photoactivated 1 to platinate DNA, this suggests that th

5 sed the degree of irreversible inhibition by photoactivated 3-azioctanol.

6 eased the irreversible inhibition induced by photoactivated 3-azioctanol.

7 3-azioctanol and the irreversible effects of photoactivated 3-azioctanol.

8 c framework for formation of adducts between photoactivated 3-hydroxyphenyl azide and RNA.

9 originating from the covalent attachment of photoactivated 4 was identified.

10 th the amount of PS1 that is modifiable by a photoactivated active site-directed gamma-secretase inhi

11 lved these critical concerns by expressing a photoactivated adenylate cyclase that allows light-sensi

12 particular versatility, naturally occurring photoactivated adenylate cyclases promote the synthesis

13 resent a transgenic mouse model expressing a photoactivated adenylyl cyclase (bPAC) in sperm.

14 identified the blaC gene encoding a putative photoactivated adenylyl cyclase in the Beggiatoa sp. PS

15 Photodynamic therapy uses a photoactivating agent to selectively treat choroidal neo

16 Other photoactivating agents are being evaluated.

17 Such a photoactivated and cancer-specific synergistic therapeut

18 cI molecules in live cells by stochastically photoactivating and observing fluorescent proteins indiv

19 discrete protein population within axons is photoactivated, and then the activated population is tra

20 We found the excitation light photoactivates as well as deactivates Dronpa single mole

21 Indeed, when caged Tbeta4 was locally photoactivated at the wings of locomoting keratocytes, s

22 oactivatable GFP)-tagged neurofilaments from photoactivated axonal segments in cultured dorsal root g

23 eled with a fluorescent probe or linked to a photoactivated bead, respectively.

24 med the appropriate disulfide bond, could be photoactivated but with reduced sensitivity, and underwe

25 When OCP is photoactivated by strong blue-green light, it is able to

26 e dark on the time scale of hours but can be photoactivated by UV light to regenerate YFP(-) within s

27 Fluorescent steroids photoactivated by visible light may be useful for modula

28 The combination of this photoactivated catalyst with the fidelity and functional

29 t Drosophila ligands; alternatively, Rac was photoactivated centrally within a single cell.

30 mbrane photosynthetic protein, in its robust photoactivated charge separation with near unity quantum

31 nment at their interfaces to ensure enhanced photoactivated charge transfer under visible light.

32 complexes for photodynamic therapy (PDT) and photoactivated chemotherapy (PACT), and discuss the chal

33 f the safety and efficacy of ruthenium-based photoactivated chemotherapy compounds in a tumor xenogra

34 ontext, 1 is a very promising candidate as a photoactivated CO releasing moiety (photoCORM) with pote

35 e data could be useful for future studies of photoactivated Co-bleomycin and Co-bleomycin analogues i

36 driving forces in a suspension of synthetic photoactivated colloidal particles.

37 dicating that the contact is enhanced in the photoactivated complex.

38 PIF1 interacts specifically with the photoactivated conformer of phytochromes A and B, sugges

39 The photoactivated conformer of the photoreceptor Pfr has be

40 njugation of a CO-releasing molecule (here a photoactivated CORM) to the 5'-OH ribose group of vitami

41 ted by reacting mono-cysteine mutants with a photoactivated cross-linker.

42 biotin on the carboxy terminus, as well as a photoactivated cross-linking group (benzophenone), also

43 -intercalating ruthenium complex to create a photoactivated cross-linking reagent.

44 Photoactivated cross-linking using the cysteine reagent

45 P1 activity through direct interactions with photoactivated CRYs are not fully understood.

46 As such they approach ideality for photoactivated depot materials.

47 We previously described the photoactivated depot or PAD approach that allows for the

48 In this work, we create materials that form photoactivated depots of insulin without the need for po

49 rystal structures of both ground state and a photoactivated deprotonated intermediate of bovine rhodo

50 l transition from the crystal structure of a photoactivated deprotonated state of rhodopsin to the lo

51 Moreover, a photoactivated derivative of 25-HC does not cross-link t

52 act cells was demonstrated by showing that a photoactivated derivative of cholesterol cross-links to

53 the C-terminal transmembrane domain using a photoactivated derivative of cholesterol.

54 Photoactivated disinfection (PAD) could support the peri

55 The first photoactivated doped quantum dot vector for metal-ion re

56 oresponsive materials, molecular motors, and photoactivated drugs.

57 lectivity of the probe and revealed that the photoactivated dye does not diffuse away from the origin

58 lso been shown that Verteporfin can have non-photoactivated effects such as interference with the YAP

59 sibly switch between stable dark-adapted and photoactivated end states.

60 mes onto dynein by combining live imaging of photoactivated endosomes and fluorescent dynein with mat

61 lity of proteins as targets of thermally and photoactivated enediynes has been confirmed at the molec

62 e is the first phytochrome with a non-kinase photoactivated enzymatic activity.

63 nstrate a practical application of a unique, photoactivated enzyme but also pave the way to selective

64 Utilizing the photoactivated escape properties, we can regulate the nu

65 The photoactivated evolution of a series of enantiomerically

66 mer in the red light-absorbing state and the photoactivated far-red light-absorbing state revealed a

67 alogous experimental studies for the case of photoactivated Fe precatalyst 2 suggested that the activ

68 especially evident at long intervals between photoactivating flashes.

69 single-molecule fluorescence microscopy and photoactivated fluorescence microscopy.

70 The obtained results suggest that the photoactivated form of OCP represents a molten globule-l

71 tion factor, interacts specifically with the photoactivated form of phytochrome B (phyB).

72 ain progenitors, we created a fate map using photoactivated gene expression to mark cells originating

73 Photoactivated gene expression was also used either to k

74 By measuring changes in fluorescence of a photoactivated GFP protein targeted to mitochondria, we

75 eveloped an imaging method that combines the photoactivated green fluorescent protein (PA-GFP) and fl

76 re-activity relations, a ligand in which the photoactivated group was extended from the 3-position of

77 e mutant, designated BlgC, was found to have photoactivated guanylyl cyclase in vitro.

78 exchange and with nearly all of the reported photoactivated H/D exchange studies, the UV-induced H/D

79 a caged form of thymosin beta4 (Tbeta4) was photoactivated in a defined local region of locomoting f

80 PAiRFPs can be photoactivated in a spatially selective manner in mouse

81 ChR2-transduced C1 neurons were photoactivated in conscious rats while EEG, neck muscle

82 Endogenous receptors can be photoactivated in neurons and astrocytes with pharmacolo

83 alpha(2)-[P(2)W(17)O(61)](10-), that can be photoactivated in the presence of 2-propanol to transfer

84 ch to create therapeutic vectors that can be photoactivated in vivo with high spatial and temporal co

85 gh single-channel conductance but reversibly photoactivates in blue light.

86 Silencing activity in dentate nucleus by photoactivating inhibitory Purkinje cells in the cerebel

87 cross-link supports the assignment that the photoactivated intermediate is the ketenimine or a keten

88 cross-strand cross-link, indicating that the photoactivated intermediate reacts broadly with function

89 e intermediates were very long-lived (>12 h, photoactivated lapachenole), others existed for millisec

90 Here, we combine photoactivated light microscopy with quantitative statis

91 ery of the photosensitizers, as well as, the photoactivating light and to establish dosimetric correl

92 sensitizer drugs are minimally toxic and the photoactivating light itself is non-ionizing.

93 sis of various stereopolymers by combining a photoactivated living polymerization, named photoinduced

94 d emission depletion (g-STED) microscopy and photoactivated localisation microscopy (PALM).

95 l assay for transposase-accessible chromatin-photoactivated localization microscopy (3D ATAC-PALM) th

96 Here, we describe an approach to cryogenic photoactivated localization microscopy (cPALM) that perm

97 and reliably counted in our interferometric photoactivated localization microscopy (iPALM) setup.

98 Here, we introduce interferometric photoactivated localization microscopy (iPALM), the comb

99 h two- and three-dimensional applications of photoactivated localization microscopy (PALM and iPALM,

100 By using photoactivated localization microscopy (PALM) and an exp

101 ase p56lck (Lck) using single and dual-color photoactivated localization microscopy (PALM) and direct

102 uperresolution microscopy techniques such as Photoactivated Localization Microscopy (PALM) and Stocha

103 se localization of single molecules, such as photoactivated localization microscopy (PALM) and stocha

104 per-resolution microscopy techniques such as photoactivated localization microscopy (PALM) and stocha

105 Here we expand the scope of SRM to photoactivated localization microscopy (PALM) imaging of

106 We used photoactivated localization microscopy (PALM) in rat hip

107 of molecular positions mapped via live-cell Photoactivated Localization Microscopy (PALM) is a power

108 Photoactivated localization microscopy (PALM) is a power

109 Photoactivated localization microscopy (PALM) is a power

110 l feature of most of the techniques based on photoactivated localization microscopy (PALM) or stochas

111 localization microscopy (SMLM)-for example, photoactivated localization microscopy (PALM) or stochas

112 lecule-based super-resolution imaging method Photoactivated Localization Microscopy (PALM) reveals th

113 Photoactivated localization microscopy (PALM) reveals th

114 We created a high-throughput modality of photoactivated localization microscopy (PALM) that enabl

115 We used quantitative photoactivated localization microscopy (PALM) to analyze

116 Here, we report the use of two-color photoactivated localization microscopy (PALM) to determi

117 We combined photoactivated localization microscopy (PALM) with live-

118 er-resolution imaging, which was realized by photoactivated localization microscopy (PALM) with low-p

119 photoactivation microscopy, super-resolution photoactivated localization microscopy (PALM), and singl

120 In the present work, we demonstrate that photoactivated localization microscopy (PALM), in combin

121 lution stimulated emission depletion (STED), photoactivated localization microscopy (PALM), stochasti

122 ization of individual fluorescent molecules [photoactivated localization microscopy (PALM), stochasti

123 rons at approximately 25 nm resolution using photoactivated localization microscopy (PALM).

124 modeling, and single-molecule counting with photoactivated localization microscopy (PALM).

125 lution microscopy in whole fixed cells using photoactivated localization microscopy (PALM).

126 ated emission depletion (STED) microscopy or photoactivated localization microscopy (PALM).

127 lution techniques such as one- and two-color photoactivated localization microscopy (PALM).

128 ate live-cell super-resolution imaging using photoactivated localization microscopy (PALM).

129 ayers in advanced microscopy schemes such as photoactivated localization microscopy (PALM).

130 The approach, called pair correlation photoactivated localization microscopy (PC-PALM), uses a

131 s using single particle tracking combined to photoactivated localization microscopy (sptPALM).

132 stochastic optical reconstruction microscopy/photoactivated localization microscopy (STORM/PALM) to d

133 Here, by combining super-resolution imaging (photoactivated localization microscopy [PALM]) and singl

134 Using photoactivated localization microscopy and single-molecu

135 Here we present a multicolour, photoactivated localization microscopy approach for imag

136 distribution of LacI in live bacteria using photoactivated localization microscopy combined with sin

137 ion of scaffold proteins was determined from photoactivated localization microscopy experiments, and

138 cilia by optimizing single-particle tracking photoactivated localization microscopy for IFT88-mEOS4b

139 bimolecular fluorescence complementation and photoactivated localization microscopy for super-resolut

140 paired rsKame with PAmCherry1 in a two-color photoactivated localization microscopy imaging method to

141 stochastic optical reconstruction microscopy/photoactivated localization microscopy imaging, and fluo

142 pecific protein degradation and quantitative photoactivated localization microscopy in strains with a

143 ngle-molecule localization microscopy (e.g., photoactivated localization microscopy or stochastic opt

144 ay for transposase-accessible chromatin with photoactivated localization microscopy revealed that the

145 mes less than mEos2, making Dendra2 a better photoactivated localization microscopy tag than mEos2 fo

146 Furthermore, we use photoactivated localization microscopy to determine the

147 Here, we use photoactivated localization microscopy to localize indiv

148 lso provides an example of applying tracking photoactivated localization microscopy to studies of low

149 We used single and two-color photoactivated localization microscopy to study complexe

150 ation microscopy (iPALM), the combination of photoactivated localization microscopy with single-photo

151 ion fluorescence microscopy (interferometric photoactivated localization microscopy) to map nanoscale

152 Here we describe a correlated cryo-PALM (photoactivated localization microscopy)-CET method for l

153 athway, in T cell membranes using high-speed photoactivated localization microscopy, dual-color fluor

154 sion depletion, structured illumination, and photoactivated localization microscopy, have enabled imp

155 Using fluorescence photoactivated localization microscopy, we detected full

156 Using photoactivated localization microscopy, we measured move

157 Using photoactivated localization microscopy, we reveal that t

158 We used this method--termed photoactivated localization microscopy--to image specifi

159 fluorescent protein and a popular marker for photoactivated localization microscopy.

160 within a diffraction-limited area when using photoactivated localization microscopy.

161 timulated emission depletion microscopy, and photoactivated localization microscopy.

162 photoactivation localization microscopy and photoactivated localization microscopy.

163 opy, structured illumination microscopy, and photoactivated localization microscopy.

164 ver, requires markers that can be reversibly photoactivated many times.

165 Photoactivated materials have found widespread use in bi

166 rehensively discuss photochemical reactions, photoactivated materials, and their use in state-of-the-

167 Starting with photochemical reactions and photoactivated materials, we then discuss principles, ap

168 stribution of single BfpB molecules fused to photoactivated mCherry.

169 Herein, we show that to preserve photoactivated molecular deformation on the macroscopic

170 One EPI-nitrene photoactivated molecule was incorporated in each subunit

171 g intracellular protein dynamics by tracking photoactivated molecules that are the only visible GFPs

172 ions of a central auditory optoprosthesis by photoactivating mouse auditory midbrain neurons that eit

173 This involves a photoactivated multicomponent reaction, performed both i

174 A photoactivated neutral organic super electron donor clea

175 The four photoactivated nitrene probes modified AChBP with up to

176 cation, engineering, and characterization of photoactivated nucleotidyl cyclases that can be used to

177 A single photoactivated OCP bound to the core of the PBS affords

178 te of photoactivity and the stability of the photoactivated OCP, suggesting that the activated OCP ha

179 e report a negative tone photoresist using a photoactivated olefin metathesis catalyst, which can be

180 For stimuli that photoactivated one rhodopsin per Galphat the rod OS swel

181 s require fluorophores whose emission can be photoactivated or photoswitched.

182 intermediates, and the less well understood photoactivated oxidative redding phenomenon.

183 The photoactivated PAmCherry1 exhibits a non-coplanar anioni

184 recorded from birthdated abDGCs in mice and photoactivated parvalbumin (PV) and somatostatin (SST) i

185 Photoactivated pattern formation in functional polymers

186 Here we demonstrate that photoactivated pattern formation on azobenzene-containin

187 ye-terminator sequencing fragments using the photoactivated PC chip and slab gel electrophoresis prod

188 ersion between a dark-adapted Pr state and a photoactivated Pfr state.

189 nds several phototropins specifically in the photoactivated Pfr state.

190 s evidence indicates that the binding of the photoactivated photoreceptor molecule to PIF3 induces ra

191 al mechanism of primary signal transfer from photoactivated photoreceptor to binding partner, and tha

192 ical and genetic evidence indicates that the photoactivated phy molecule acts within 60 s to induce t

193 lves direct, intranuclear interaction of the photoactivated phy molecule with PIF3, a basic helix-loo

194 adation induced by direct interaction of the photoactivated phy molecule with the transcription facto

195 llowing light-induced nuclear translocation, photoactivated phy molecules bind to and induce rapid ph

196 ivity is reversed upon exposure to light, by photoactivated phy molecules that induce degradation of

197 PPKs are directly involved in catalysing the photoactivated-phy-induced phosphorylation of PIF3 in vi

198 toactivated phyB nor artificial retention of photoactivated phyB in the cytosol provides detectable b

199 The interaction between PIF3 and photoactivated phyB leads to the rapid phosphorylation a

200 ng that the consequences of interaction with photoactivated phyB may differ among PIFs.

201 ther artificial nuclear translocation of non-photoactivated phyB nor artificial retention of photoact

202 hese data indicate that signal transfer from photoactivated phyB to its primary signaling partner(s)

203 gest the absence of a cytosolic pathway from photoactivated phyB to light-responsive genes.

204 ss, whereas in the light, the interaction of photoactivated phyB with PIF5 causes degradation of the

205 of the effects of PIF feedback modulation of photoactivated-phyB abundance.

206 scillates as a balance between synthesis and photoactivated-phytochrome-imposed degradation, with max

207 Moreover, photoactivated phytochromes bind to and induce rapid deg

208 vel phytochrome signaling mechanism in which photoactivated phytochromes directly interact with HMR a

209 icans grew on both media and produced a pink photoactivated pigment on m-DTDP agar.

210 PL-VS projections reduced avoidance, whereas photoactivating PL-BLA projections increased avoidance.

211 Photoactivating PL-VS projections reduced avoidance, whe

212 In this manuscript, we discuss the use of photoactivated polycarbonate (PC) for purification of dy

213 We discuss the use of a photoactivated polycarbonate (PPC) microfluidic chip for

214 Perylenequinones are a class of photoactivated polyketide mycotoxins produced by fungal

215 orial stimulation by low-dose artemisinin to photoactivate PPIX to produce cytotoxic reactive oxygen.

216 Photoactivated probes have gained interest as experiment

217 Most bacteriophytochromes work as photoactivated protein kinases.

218 PALM/STORM rely on photoactivated proteins or photoswitching dyes, respecti

219 The method is applied to the photoactivated proton pump, bacteriorhodopsin, using con

220 We conclude that the photoactivated PYP domain in Ppr accelerates recovery of

221 In cultured mammalian cells, the effect of photoactivated pyr-TFO-directed DNA damage was to induce

222 Here we demonstrate that photoactivated pyrene-conjugated TFOs (pyr-TFOs) induce

223 1 PHOTOACTIVATED QUASAR3 (PAQUASAR3) REPORTS NEURONAL ACTI

224 be spectroscopy, and in elucidating the main photoactivated reactive paths.

225 The photoactivated receptor in DDM is dominated by one confo

226 nanodiscs, the ensemble of substates in the photoactivated receptor spontaneously decays to that cha

227 rmation of NpHtrII for signal relay from the photoactivated receptor to the kinase-binding region of

228 ins upon transition from the basic orange to photoactivated red OCP form.

229 A broadening of the photoactivated region occurred as MTs moved bidirectiona

230 Neurofilaments departed from the photoactivated regions at rapid velocities, but the over

231 Second, direct focal photoactivated release of the microtubule-stabilizing dr

232 Photoactivated reversible addition fragmentation chain t

233 Binding of purified Gt to photoactivated Rho (Rho*) in n-dodecyl beta-D-maltoside

234 onstrated the modularity of this approach by photoactivating RhoA with high spatiotemporal resolution

235 vity 10(5)- to 10(6)-fold lower than that of photoactivated rhodopsin (meta II).

236 Photoactivated rhodopsin (R) catalyzes nucleotide exchan

237 robable protein-protein interactions between photoactivated rhodopsin (R*) and experimentally determi

238 The decay of photoactivated rhodopsin (R*) and inactivation of transd

239 reliable 3D model for the complex formed by photoactivated rhodopsin (R*) and its G-protein, transdu

240 nd utilized a model of the interface between photoactivated rhodopsin (R*) and transducin (Gt), its G

241 e of the G(t)alpha(340-350) peptide bound to photoactivated rhodopsin (R*) geometrically suggests a c

242 he interaction between transducin (G(t)) and photoactivated rhodopsin (R*), 14 analog peptides were d

243 ) as efficient in activating transduction as photoactivated rhodopsin (Rh*) in WT mice.

244 Transitory binding between photoactivated rhodopsin (Rho* or Meta II) and the G pro

245 t subunit dissociation caused by exposure to photoactivated rhodopsin (Rho*).

246 the rhabdomere possibly by interacting with photoactivated rhodopsin 1 (Rh1*).

247 nal, is released in the rod outer segment by photoactivated rhodopsin after light excitation.

248 eased in rod photoreceptor outer segments by photoactivated rhodopsin and is eliminated through reduc

249 ouse rods, but the complex formation between photoactivated rhodopsin and transducin is severely comp

250 Complex formation between photoactivated rhodopsin and transducin was measured by

251 nsducin, Gtalpha 340-350, within cavities of photoactivated rhodopsin formed by different energetical

252 er/Thr kinase responsible for termination of photoactivated rhodopsin in rod photoreceptor cells.

253 The ability of photoactivated rhodopsin to achieve the enzymatically ac

254 The release of all-trans retinal from photoactivated rhodopsin was measured in purified rod ou

255 ions is superstoichiometric to the amount of photoactivated rhodopsin, exceeding it by at least 30-fo

256 resulting spin-labeled Galphabetagamma with photoactivated rhodopsin, followed by rhodopsin-catalyze

257 dehyde all-trans-retinal that is released by photoactivated rhodopsin, to all-trans-retinol (vitamin

258 is visual arrestin responsible for quenching photoactivated rhodopsin, which moves into photoreceptor

259 pposite of the side of arrestin-1 that binds photoactivated rhodopsin.

260 state rhodopsin, and hydrolysis of SB using photoactivated rhodopsin.

261 receptors requires efficient inactivation of photoactivated rhodopsin.

262 Corneal CXL with photoactivated riboflavin did not shorten the time to co

263 ter internalization, the photosensitizer was photoactivated, significantly increasing the cytotoxicit

264 We used photoactivated single-molecule tracking to discriminate

265 nd state (Pr) and a far-red-light-absorbing, photoactivated state (Pfr).

266 nerate a three-dimensional (3D) model of the photoactivated state (R*) of bovine rhodopsin (Rh).

267 ound state Pr, and a far-red light-absorbing photoactivated state Pfr.

268 bing dark state Pb and green light-absorbing photoactivated state Pg, combined with paired crystallog

269 In the photoactivated state, the Schiff base linking the chromo

270 enesis produced an enzyme with a more stable photoactivated state.

271 distance distributions in both the dark and photoactivated states of rhodopsin.

272 distance distributions in both the dark and photoactivated states of rhodopsin.

273 ts directly demonstrate the coupling of SRII photoactivated states to histidine kinase activity, prev

274 rotonated states that represent the dark and photoactivated states, respectively.

275 (PA-GFP) have been solved in the native and photoactivated states, which under 488 nm illumination a

276 A photoactivated-strengthening polymer network is reported

277 y between the active opsin structure and the photoactivated structures in crystallo near the retinal

278 orescence microscopy, and PAGFP was sparsely photoactivated such that polarized fluorescence identifi

279 bunit and used as sites of attachment of the photoactivated sulfhydryl reagent 4-(N-maleimido)benzoph

280 The gDNA was selectively captured on this photoactivated surface in an immobilization buffer, whic

281 ur results reveal that LH2 complexes undergo photoactivated switching to a quenched state, likely by

282 These simulations demonstrated that locally photoactivating Tbeta4 in keratocytes could potentially

283 In search of strategies to photoactivate the luminescence of semiconductor quantum

284 e usefulness of this approach to selectively photoactivate the production of singlet oxygen in ROS st

285 block blood flow in the targeted artery, we photoactivated the rose bengal by illuminating the longi

286 We demonstrated its utility by photoactivating the beta-catenin pathway, achieving a tr

287 n of light can be used for a wide variety of photoactivated therapies, especially light-triggered DDS

288 esented as a compound II species that can be photoactivated to compound I.

289 roduct (e.g., chlorate and chlorite) through photoactivated transformations.

290 n is caused by an instability created by the photoactivated transitions between two immiscible states

291 les fail to migrate in a mutant deficient in photoactivated TRP calcium channels.

292 eutic devices with potential applications in photoactivated tumor therapy.

293 tion, the orange carotenoid protein (OCP) is photoactivated under excess light conditions and binds t

294 ected with the caged FAK peptide and locally photoactivated using a focused laser beam.

295 as confirmed using optogenetic techniques to photoactivate V1 corticotectal terminals in slices of th

296 Photoactivated VCOP(D108A) had kinetics comparable to th

297 and likely reflects the spontaneous decay of photoactivated visual pigment.

298 The photoactivated W(CO)(6)/DABCO/THF system has been used f

299 sh-pull fluorophore so that it is dark until photoactivated with a short burst of low-intensity viole

300 cs with theranostic nanoparticles, which are photoactivated within highly localized space near tumour