ライフサイエンスコーパス: photosensitivity

1 utaneous responses to ultraviolet radiation (photosensitivity).

2 is responsible for hemolytic anemia and skin photosensitivity.

3 ge, but the drug dose required and cutaneous photosensitivity.

4 t high light intensities because of enhanced photosensitivity.

5 nistic Ox-GPCs in the pathophysiology of XPA photosensitivity.

6 d neurological disease and nonmalignant skin photosensitivity.

7 ed oxidative damage may mediate the observed photosensitivity.

8 icles with similar asymmetric morphology and photosensitivity.

9 in erythrocytes, skin, and liver, and acute photosensitivity.

10 ut mice resulted in restoration of circadian photosensitivity.

11 planted mice showed minimal evidence of skin photosensitivity.

12 reatment was associated with a selective UVA photosensitivity.

13 o prevent liver disease and significant skin photosensitivity.

14 gnal processing) with nongenetically enabled photosensitivity.

15 e group had a higher incidence of nausea and photosensitivity.

16 ster formation (especially in childhood) and photosensitivity.

17 tibody positivity followed by malar rash and photosensitivity.

18 not of melanopsin expression, decreased iris photosensitivity.

19 tability, CRY-TIM interaction, and circadian photosensitivity.

20 melanopsin, a photopigment that confers this photosensitivity.

21 e most common adverse event was dose-related photosensitivity.

22 out specific potential toxicities, including photosensitivity.

23 heral vision, mesopic peripheral vision, and photosensitivity.

24 editary coproporphyria can present with skin photosensitivity.

25 d neither polyneuropathy nor exacerbation of photosensitivity.

26 s into the plasma and results in severe skin photosensitivity.

27 for rare heritable disorders associated with photosensitivity.

28 ritis, Raynaud's phenomenon, malar rash, and photosensitivity.

29 ntiation, and others an increase in cellular photosensitivity.

30 sual thalamus only in epilepsy patients with photosensitivity.

31 ocurrents, persistent photoconductivity, and photosensitivity.

32 toms, emotions, functioning, body image, and photosensitivity.

33 ed states were generated, enabling excellent photosensitivity.

34 ty and slow clearance from the body, causing photosensitivity.

35 ntal and sensorial retardation and cutaneous photosensitivity.

36 d inflammatory mechanisms that contribute to photosensitivity.

37 system reduces excessive light and enhances photosensitivity.

38 period-dependent development of reproductive photosensitivity.

39 hotosensitive patients and in people without photosensitivity.

40 ed by progeriod features, growth failure and photosensitivity.

41 develop cancer, although they often exhibit photosensitivity.

42 ased OPN4X photopigment conferring intrinsic photosensitivity.

43 tabolism frequently characterized by extreme photosensitivity.

44 h larvae with chd2 knockdown were tested for photosensitivity.

45 rkedly enhanced mild innate zebrafish larval photosensitivity.

46 e defective transcription-coupled repair and photosensitivity.

47 odystrophy (TTD), which share only cutaneous photosensitivity.

48 ffective erythropoiesis and devastating skin photosensitivity.

49 the most part only associated with increased photosensitivity.

50 eginning of outer-segment disc formation and photosensitivity.

51 etaxel plus vandetanib arm and included rash/photosensitivity (11% v 0%) and diarrhea (7% v 0%).

52 ); (ii) genetic generalized epilepsy without photosensitivity, 13 patients (mean age 25 +/- 11 years)

53 luded: (i) genetic generalized epilepsy with photosensitivity, 16 subjects (mean age 25 +/- 10 years)

54 first criterion (34.5%); it was followed by photosensitivity (18.8%).

55 th protoporphyria, including (1) approach to photosensitivity, (2) managing iron deficiency in protop

56 nsitive rhodopsins like Chrimson shifted the photosensitivity 20 nm toward red light and accelerated

57 %-2%), blue-gray skin discoloration (4%-9%), photosensitivity (25%-75%), hypothyroidism (6%), hyperth

58 vs 15 [4%]), anorexia (37 [11%] vs 13 [4%]), photosensitivity (42 [12%] vs 6 [2%]), rash (111 [32%] v

59 tients, 48%), nausea (58 patients, 45%), and photosensitivity (52 patients, 40%).

60 ficantly reduced allergen-induced changes in photosensitivity (60%, P = 0.0002), chemosis (50%, P = 0

61 ), malar rash (56.0%), discoid rash (34.2%), photosensitivity (60.9%), and oral/nasal ulcerations (43

62 ctum revealed responses that varied in their photosensitivities: (a) low-sensitivity OFF-RGCs that se

63 a is a chronic skin disease characterized by photosensitivity, abnormal dermal vascular behavior, inf

64 Ex-apt@LuCXB was found to display good photosensitivity, acceptable biocompatibility, and robus

65 ton resonances, that have demonstrated large photosensitivity across the UV spectrum.

66 Photophore photosensitivity allows us to reconsider the organ's rol

67 se change may be used to alter the degree of photosensitivity, although there is limited information

68 Defective NER is associated with photosensitivity and a high skin cancer incidence.

69 rties including high electron mobility, high photosensitivity and an excellent electron accepting nat

70 ential mechanisms of voriconazole-associated photosensitivity and carcinogenesis and identify areas t

71 g patients with CEP but usually combine skin photosensitivity and chronic hemolytic anemia, the sever

72 Anti-Ro antibodies are correlated with photosensitivity and cutaneous lesions in these patients

73 bnormal OS morphology and reduced single rod photosensitivity and dark currents.

74 Melanopsin is required for ipRGC photosensitivity and for behavioural photoresponses that

75 Here we investigate the intrinsic photosensitivity and functioning of HCs from primary cul

76 While mechanisms of photosensitivity and genetic underpinnings associated wi

77 FS syndrome highlight the high prevalence of photosensitivity and hair and nail disorders.

78 ator) and report that it reversed their skin photosensitivity and hemolytic anemia.

79 f heme biosynthesis that manifests as severe photosensitivity and hepatotoxicity.

80 photosystem I (PSI) accumulation, exhibited photosensitivity and highly reduced abundance of PSI und

81 V-induced DNA damage is associated with skin photosensitivity and increased skin cancer risk.

82 rotoporphyrin in amounts sufficient to cause photosensitivity and liver disease.

83 lated Malacosteus genes were associated with photosensitivity and may relate to its unique visual eco

84 with complete colour blindness, low acuity, photosensitivity and nystagmus.

85 e accumulation of porphyrins that cause skin photosensitivity and occasionally severe liver damage.

86 a canine generalized myoclonic epilepsy with photosensitivity and onset in young Rhodesian Ridgeback

87 essential and synergistic roles in affecting photosensitivity and OS morphogenesis of rod photorecept

88 ent and insensitive but by P6 show increased photosensitivity and persistence.

89 ations of CEP include bone fragility, severe photosensitivity and photomutilation.

90 ionarily conserved mechanism determining the photosensitivity and photoreactivity of plant CRYs.

91 ecognized mechanism underlying the different photosensitivity and photoreactivity of these two closel

92 Photosensitivity and photosensitization could be demonst

93 the mechanism linking this mutant protein to photosensitivity and poikiloderma remains to be determin

94 ition, but it has been complicated by severe photosensitivity and polyneuropathy.

95 The most common adverse events were photosensitivity and rash.

96 uisite eye pain, inability to open the eyes, photosensitivity and reduced vision.

97 Thus, T lymphocytes possess intrinsic photosensitivity and this property may enhance their mot

98 ure, modulates endothelial and smooth muscle photosensitivity and trans-retinal absorption of fluid i

99 res, a hypoplastic nose, xeroderma, and skin photosensitivity and were homozygous for the same missen

100 It is characterized clinically by acute photosensitivity and, in 2% of patients, liver disease.

101 ion by skin (leading to protracted cutaneous photosensitivity); and less than optimal photophysical p

102 Erythema, photosensitivity, and immunologic alterations represent

103 characterized by osteoskeletal deformities, photosensitivity, and increased osteosarcoma susceptibil

104 tic disease characterized by skin fragility, photosensitivity, and increased risk of squamous cell ca

105 iciency of photosynthetic electron transfer, photosensitivity, and lethality in soil.

106 with defects in the TTDN1 gene: four had no photosensitivity, and one patient exhibited cutaneous bu

107 (ACR) criteria of malar rash, discoid rash, photosensitivity, and oral ulcers, and 3 (23%) met the m

108 s of human rhodopsin's spectral sensitivity, photosensitivity, and regeneration kinetics.

109 ropy crystal structure for high polarization photosensitivity, and strong quantum confinement for exc

110 n brain pacemaker cells increases behavioral photosensitivity, and this restricted CRY expression als

111 The two different photosensitivities are demonstrated by blue light-photoc

112 Several features of ipRGC photosensitivity are characteristic of fly photoreceptor

113 The causes of photosensitivity are diverse, ranging from primary, immu

114 llenging contexts where background, loss, or photosensitivity are factors.

115 ted phospho-rhodopsin has the same molecular photosensitivity as unphosphorylated rhodopsin and that

116 metastructural properties such as increased photosensitivity as well as spectral selectivity and ran

117 phyrin IX leads to severe, painful cutaneous photosensitivity, as well as potentially life-threatenin

118 loss of Ro function could contribute to the photosensitivity associated with anti-Ro antibodies in h

119 hat these Ox-GPCs play a pivotal role in the photosensitivity associated with the deficiency of the D

120 nally, effect-modification by medication and photosensitivity-associated MC1R variants was assessed.

121 Our findings suggest that IFN-I promotes photosensitivity at least in part by inhibiting UVR-indu

122 Heterozygous mice exhibited skin photosensitivity but no liver disease.

123 ifts of their absorption maxima and enhanced photosensitivity but provide lower yields of CO formatio

124 R-driven responses in rd1 animals showed low photosensitivity, but in other respects generated a visu

125 othesize that a mechanism to suppress pineal photosensitivity by using NE released from sympathetic n

126 Some clinical treatments that cause photosensitivity can also increase skin cancer risk.

127 Thereafter, full recovery of photosensitivity coincides with regeneration and dephosp

128 mice demonstrate paradoxically increased PLR photosensitivity compared with mice mutant in visual cyc

129 Photosensitivity could also be prevented locally by impl

130 The same parameters, together with a fixed photosensitivity, could account for the steady-state pig

131 In addition to increased photosensitivity, CS patients suffer from severe develop

132 Genetic generalized epilepsy with photosensitivity demonstrated significantly greater mean

133 recessive genetic disorder characterized by photosensitivity, developmental defects, neurological ab

134 esis of a number of skin disorders including photosensitivity diseases and some types of cutaneous ma

135 s of carotenoids on cardiovascular diseases, photosensitivity diseases, cataracts, and age-related ma

136 ough the differential diagnosis of pediatric photosensitivity disorders is broad, it is often possibl

137 perception; all P > .05) or ocular symptoms (photosensitivity, dry eye, foreign body sensation, ocula

138 This high photosensitivity enables photorelease of molecules down

139 The bioinspired photosensitivity enhancer (BPE) that we have developed e

140 Cones recover their photosensitivity faster than rods after bleaching.

141 e events were grade 1 or 2 arthralgia, rash, photosensitivity, fatigue, and alopecia.

142 tinas and isolated cone cells show increased photosensitivity following exposure to blue light.

143 identify that FSHbeta establishes a state of photosensitivity for the external coincidence timing of

144 Rash and photosensitivity frequencies were higher in the simeprev

145 y was reported in the 1.0 mg/kg cohort (skin photosensitivity [grade 2]).

146 patients at a TPCS2a dose of 1.5 mg/kg (skin photosensitivity [grade 3] and wound infection [grade 3]

147 syndrome (CS) is characterized by increased photosensitivity, growth retardation, and neurological a

148 be uncovered, the literature on disorders of photosensitivity has been otherwise without many recent

149 tion and, based on this mechanism of action, photosensitivity has been previously described.

150 a single infusion, no instances of cutaneous photosensitivity have been noted in these patients.

151 New developments in the field of pediatric photosensitivity have been scant over recent years.

152 Based on their intrinsic photosensitivity, HCs may have a key dual function in th

153 a premature aging disorder characterized by photosensitivity, impaired development and multisystem p

154 We then determined the heritability of photosensitivity in 420 individuals from families ascert

155 Here, our results suggest photosensitivity in a second type of autogenic photophor

156 in complete and long-term correction of skin photosensitivity in all transplanted mice.

157 sly generated interval timing that underlies photosensitivity in birds.

158 e, however, is too slow to explain sustained photosensitivity in bright light.

159 eased in red blood cells and urine, and skin photosensitivity in CEP mice treated with deferiprone (1

160 A new paper provides direct evidence of photosensitivity in cerebrospinal fluid (CSF)-contacting

161 to topical or systemic agents may also cause photosensitivity in children.

162 determined whether CHD2 variation underlies photosensitivity in common epilepsies, specific photosen

163 nique CHD2 variants are also associated with photosensitivity in common epilepsies.

164 The development of photosensitivity in culture could be partially or comple

165 ic mechanism for the regulation of circadian photosensitivity in Drosophila.

166 Across 58 pedigrees the prevalence of photosensitivity in first-degree relatives was 20.9% com

167 unidentified direction toward achieving high photosensitivity in imaging systems.

168 ir acutely isolated retinas revealed reduced photosensitivity in M1 ipRGCs, but not other ipRGC types

169 d rhodopsin, retinoids, phosphorylation, and photosensitivity in mice during a 90 min illumination fo

170 Photosensitivity in most echinoderms has been attributed

171 d polyspike wave discharges, with documented photosensitivity in most.

172 evious complementation studies show that the photosensitivity in nearly all of the studied patients i

173 llumination remains unknown, but evidence of photosensitivity in photophores may indicate a dual func

174 de-containing DNA, providing a mechanism for photosensitivity in RNase H2-associated SLE.

175 n achieving low discrete dark noise and high photosensitivity in rod pigments for dim-light vision.

176 Here, we investigate photosensitivity in the bioluminescent light organs (pho

177 hotochemical quenching, leading to increased photosensitivity in the mutant plants under light stress

178 Photosensitivity in the pediatric patient is caused by a

179 As-grown heterostructures exhibit inherent photosensitivity in the visible light spectrum with high

180 n two-photon fluorescent imaging or enhanced photosensitivity in two-photon sensitization, respective

181 Rat RGCs that exhibited intrinsic photosensitivity invariably expressed melanopsin.

182 te cutaneous lupus erythematosus (SCLE), and photosensitivity is a common symptom.

183 for a scientific commentary on this article.Photosensitivity is a condition in which lights induce e

184 Photosensitivity is a heritable abnormal cortical respon

185 Photosensitivity is a sensitivity to UV radiation (UVR)

186 species (ROS) in ilr3-4 and pye, suggesting photosensitivity is due to a PSII defect resulting in RO

187 Importantly, circadian photosensitivity is increased in a cry-overexpressing st

188 We find that all ipRGC photosensitivity is melanopsin dependent.

189 P synthase pgr5 double mutant, a decrease in photosensitivity is observed compared with the single AT

190 Clinical photosensitivity is present in approximately 50% of TTD

191 Photosensitivity is prominent in a very rare epileptic e

192 In single rods of Rp1L1-/-, photosensitivity is reduced, similar to that of Rp1-/-.

193 hototransistors with high and broad spectral photosensitivity is reported.

194 se role of melanopsin in supporting cellular photosensitivity is unconfirmed.

195 tery occlusion, and (3) the possibility that photosensitivity may have a role in the pathogenesis of

196 001) and had earlier onset of photosensitivity (mean [SD] age, 35.5 [3.9] vs 47.5 [2.9

197 r cellular content estimated previously from photosensitivity measurements and retinal extraction yie

198 egulation of type I interferons, which drive photosensitivity, myeloid-cell recruitment and amplifica

199 keratoacanthoma or squamous-cell carcinoma, photosensitivity, nausea, and diarrhea; 38% of patients

200 Rash, photosensitivity, nausea, vomiting, and diarrhea were th

201 Photosensitivity occurred more frequently with acetylcys

202 In summary, we have shown that the photosensitivity of alkyl cobalamin conjugates can be tu

203 In parallel, we tested the photosensitivity of an ascorbate-deficient xanthophyll c

204 phorylation of the CCE domain determines the photosensitivity of Arabidopsis CRY2.

205 lustrated by the observation that the strong photosensitivity of Chlamydomonas reinhardtii cells depl

206 ranscribed strand accounts for the increased photosensitivity of CS patients, the reason for developm

207 k per second reveals an unexpected degree of photosensitivity of fluorophore-containing cells.

208 We ruled out the possibility that intrinsic photosensitivity of Gal4s1156t+ SINs contribute to the m

209 method to significantly improve the overall photosensitivity of imaging systems.

210 ine, it was possible to estimate the in vivo photosensitivity of mouse rhodopsin to be about 6 x 10(-

211 Photosensitivity of PDT-treated cells was measured by a

212 impairs photosynthetic control and increases photosensitivity of photosystem (PS) I, leading to seedl

213 ase that is linked, at least in part, to the photosensitivity of PKCepsilon transgenic mice.

214 Under the in vitro conditions, the photosensitivity of RGR is at least 34% that of bovine r

215 opsin mutants, to improve the unusually high photosensitivity of rhodopsin are proposed.

216 The photosensitivity of Rlbp1(-/-) mice is normal but rhodop

217 Leveraging the high photosensitivity of Ru compounds, we demonstrate rapid a

218 PSs), optimal drug release profiles, and the photosensitivity of surrounding tissues.

219 We demonstrate that the photosensitivity of the C60 nanorods can be enhanced ~40

220 The photosensitivity of the carbon monoxide complex of myogl

221 acellular milieu, concomitant with a reduced photosensitivity of the cells.

222 lso commensurate with the relative long-term photosensitivity of the corresponding solids and solutio

223 al day 10 (P10); however, the development of photosensitivity of the ipRGCs remains largely unexplore

224 he same genotype, and that for the intrinsic photosensitivity of the melanopsin-expressing retinal ga

225 This photosensitivity of the molecule-metal interface highlig

226 The visual pigments that underlie the photosensitivity of the retina have been examined in a n

227 hich is likely to directly contribute to the photosensitivity of these patients.

228 We find that the photosensitivity of this circuit is conferred by vertebr

229 RBCs and urine, as well as reversion of skin photosensitivity on bortezomib treatment.

230 Since the moiety that confers photosensitivity on opsins is the chromophore retinal, w

231 ) vs SPTs I to IV (89 [74%]) were younger at photosensitivity onset (median age, 24 years [IQR, 15-37

232 ed or photodistributed eczema; median age at photosensitivity onset was 37 years (range, 1-72 years).

233 trainment, and either their melanopsin-based photosensitivity or ability to relay rod/cone input is s

234 ns capable of alleviating porphyrin-mediated photosensitivity or decoupling dieting and fasting from

235 etely recovered to have had fever, headache, photosensitivity, or neck stiffness during their acute i

236 Photosensitivity, or photoparoxysmal response (PPR), is

237 A 44-year-old man developed blurry vision, photosensitivity, orthostasis, constipation, and acrodys

238 American Indian ancestry protected against photosensitivity (P < 0.0001, OR 0.58 [95% CI 0.44-0.76]

239 TLR3 rs3775296-T was associated with photosensitivity (p = 0.0020) and anemia (p = 0.0082).

240 portant cutaneous adverse effects, including photosensitivity, photocarcinogenesis and eczematous ski

241 myelination with calcium deposits, cutaneous photosensitivity, pigmentary retinopathy and/or cataract

242 myelination with calcium deposits; cutaneous photosensitivity; pigmentary retinopathy, cataracts, or

243 utaneous porphyrias with skin blistering and photosensitivity: porphyria cutanea tarda; congenital er

244 The prevalence of photosensitivity (predominantly polymorphic light erupti

245 e), leads to acute visceral attacks and skin photosensitivity, presenting as blistering and fragility

246 It is known that OFF-RGCs with distinct photosensitivity profiles form parallel visual channels

247 Diverse photosensitivity profiles were also observed using pan-n

248 tion provides a connection between cutaneous photosensitivity, protein damage, and increased skin can

249 ancestry were significantly associated with photosensitivity (Ptrend=0.0021, odds ratio for highest

250 though the major symptom of this disorder is photosensitivity, rarely, it can cause progressive liver

251 s were reported by six patients and included photosensitivity, rash, and headache.

252 thralgia (1259 [39%]), fatigue (1093 [34%]), photosensitivity reaction (994 [31%]), alopecia (826 [26

253 ze the ligands that control iron solubility, photosensitivity, reactivity, and bioavailability.

254 livered immediately after the first, but its photosensitivity recovered slowly in the dark, a process

255 ght responsive from birth (P0) and that this photosensitivity requires melanopsin expression.

256 ging, telangiectasia, neurodegeneration, and photosensitivity, resulting from a homozygous missense (

257 neurological dysfunction, cachetic dwarfism, photosensitivity, sensorineural hearing loss, and retina

258 xeroderma pigmentosum variant show clinical photosensitivity, skin neoplasias induced by ultraviolet

259 </= 24 h with FosPEG 2% and 8%, whilst skin photosensitivity studies showed Foscan(R) induces more d

260 subsequently enabled them to attain the low photosensitivity tailored to the role of circadian recep

261 Rods showed 40-220-fold higher photosensitivity than cones.

262 phylaxis include hyperkalemia, hypoglycemia, photosensitivity, thrombocytopenia, and more rare advers

263 tinal ganglion cells (ipRGCs) combine direct photosensitivity through melanopsin with synaptically me

264 ory and functional significance of intrinsic photosensitivity through the vertebrate lineage and also

265 ion and the availability of azo-dopants with photosensitivity throughout the entire visible spectrum,

266 Melanopsin imparts an intrinsic photosensitivity to a subclass of retinal ganglion cells

267 -type counterparts and displayed the typical photosensitivity to high light associated to phylloquino

268 imary, immunologically mediated disorders of photosensitivity to inherited genetic or metabolic disor

269 the active state, this protein provides high photosensitivity to the host cells.

270 Photosensitivity to ultraviolet (UV) light affects up to

271 The photopigment melanopsin confers photosensitivity upon a minority of retinal output neuro

272 cytes and hepatocytes, and resulting in skin photosensitivity upon leaching of blood protoporphyrin i

273 also to the regulation of other events whose photosensitivity varies during a diurnal cycle.

274 cells (LCs) limit keratinocyte apoptosis and photosensitivity via a disintegrin and metalloprotease 1

275 In this study, cortical function in photosensitivity was assessed using two visual aftereffe

276 apparent/innate quantum yield and the lower photosensitivity was mainly attributed to the higher bon

277 Photosensitivity was more common with vemurafenib (14 pa

278 Iris photosensitivity was not affected by retinoid depletion

279 A wider action spectrum of intrinsic photosensitivity was obtained than would be expected for

280 Photosensitivity was present in 75% of the patients and

281 ntestinal disorders, jaundice, dry skin, and photosensitivity were increased at 240 mg BID compared w

282 unconjugated hyperbilirubinemia, and rash or photosensitivity were more common in the active groups t

283 us erythematosus (lupus) is characterized by photosensitivity, where even ambient ultraviolet radiati

284 onformational flexibility, and increased the photosensitivity, which indicates a local effect in the

285 anced cortical excitability in subjects with photosensitivity, which is likely to reflect changes in

286 s (>/=18 years) undergoing investigation for photosensitivity who were diagnosed with CAD from Novemb

287 eview recent findings in the pathogenesis of photosensitivity with a focus on immune cell-stromal cir

288 ver, the double mutant exhibits an increased photosensitivity with respect to the single mutants and

289 s: All 3 cases reported a rapid reduction in photosensitivity within weeks following initiation of sy

290 otosensitive epilepsies and individuals with photosensitivity without seizures.