ライフサイエンスコーパス: physical interaction

1 MOS1 and TCP proteins have a direct physical interaction.

2 n and proteasomal degradation of Vif through physical interaction.

3 f MtRS and it renders HIF-1alpha inactive by physical interaction.

4 regulation by ceftriaxone is not mediated by physical interaction.

5 efense responses by suppressing LSU2 through physical interaction.

6 e collaboration is not dependent on a stable physical interaction.

7 , this work is the first report of an Eya-Ey physical interaction.

8 within the N terminus of Kv4.3, supporting a physical interaction.

9 visual configuration of the tool and through physical interaction.

10 events this SCM ubiquitination through their physical interaction.

11 nd provided quantitative insights into their physical interactions.

12 e model that has all its components based on physical interactions.

13 atistics provided either visually or through physical interactions.

14 (ISO), promotes enhanced Ca(V) 1.2-Ca(V) 1.2 physical interactions.

15 cells, we provide evidence for a network of physical interactions among all 44 TGCT risk SNPs and ca

16 Direct physical interactions among individual cells mediate lar

17 ransgenic larvae, we directly detect in vivo physical interactions among PPK and Balboa subunits.

18 Physical interactions among the acyl-editing enzymes wer

19 ites in Osx or Runx2 strongly disrupts their physical interaction and cooperative transcriptional eff

20 NIH-2/3 extracellular loop required for both physical interaction and gating modulation of the AMPAR.

21 ons in BRR2 and PRP16 suppresses or enhances physical interaction and growth defects in an allele-spe

22 Physical interaction and phosphorylation by CaMPK9 prote

23 peptide known to activate the SERCA pump by physical interaction and provides a means for enhancing

24 criptional regulation of gene expression via physical interaction and recruitment of RNA decay machin

25 acities is discussed, mainly focusing on the physical interactions and chemical reactions.

26 uster into a densely connected subnetwork of physical interactions and many of them are epigenetic mo

27 owed us to extend the analysis beyond binary physical interactions and revealed a system-level layout

28 undamental neural processes underlying human physical interactions and suggest advantages of interact

29 and caregivers with an understanding of the physical interactions and tasks to manage safety risks a

30 /3-SMIT1/2 coassembly permits cross talk via physical interaction, and may also be required for optim

31 ilarly, thalidomide inhibited the TBX5/HAND2 physical interaction, and the in silico docking revealed

32 ansgenic constructs, phenotypes, genetic and physical interactions, and reagents such as stocks and c

33 However, mechanisms underlying physical interactions are difficult to observe due to th

34 These physical interactions are direct, as Coy1 was efficientl

35 hat the genomic architectures of genetic and physical interactions are independent, with important im

36 The associations in STRING include direct (physical) interactions, as well as indirect (functional)

37 many applications that rely on chemical and physical interactions at surfaces.

38 owed that ChromNet revealed previously known physical interactions better than alternative approaches

39 ation capture revealed a long range (570 kb) physical interaction between a sub-region of the risk lo

40 showed that calcineurin inhibition enhances physical interaction between alpha2delta-1 and NMDARs an

41 Independent of phylogenetic distance, the physical interaction between an animal and its natural e

42 growth by apoptotic targets is dependent on physical interaction between apoptotic targets and PTECs

43 We identified a direct physical interaction between ATDC and the E3 ubiquitin l

44 We also demonstrate a physical interaction between BORIS and one of the analyz

45 We provide evidence for physical interaction between both proteins.

46 We also probed a physical interaction between both proteins.

47 Previous studies indicated that the physical interaction between C. albicans and F. nucleatu

48 a complex multifaceted mechanism underlying physical interaction between C. albicans and F. nucleatu

49 A physical interaction between Chl1 and the cohesin comple

50 Here, we show that the physical interaction between CIPK23 and the noncanonical

51 ssembly process starting from the underlying physical interaction between conductors.

52 Here, we set out to characterize the physical interaction between CRD-BP and GLI1 mRNA so as

53 binding constants of effector proteins, and physical interaction between cyclases and effectors.

54 ining entry factor usage and imply a direct, physical interaction between E1 and CLDNs.

55 cted recurring feature in this system is the physical interaction between E3 ubiquitin ligases and de

56 activity indicates that it results from the physical interaction between ELF3 and AR and that this i

57 Finally, we showed a physical interaction between EMC and viral NS4B and that

58 Further, for the first time, the physical interaction between EmoA and EmoB was observed

59 gy in SDH-deficient GISTs, allowing aberrant physical interaction between enhancer and oncogene.

60 However, how the physical interaction between FBXL5 and IRP2 is regulated

61 Hs2st modification selectively facilitates a physical interaction between Fgf17 and HS and suppresses

62 on frataxin might be in part mediated by the physical interaction between GRP75 and mitochondrial pro

63 cell fractionation and confocal microscopy; physical interaction between HDAC4/Rad51/Ubc9 by immunop

64 Thus, multiple lines of evidence indicated a physical interaction between hERG1a and hERG1b, consiste

65 Apo (apolipoprotein) M mediates the physical interaction between high-density lipoprotein (H

66 Physical interaction between hMOB3 and MST1 was essentia

67 lter splicing because they change the direct physical interaction between Hsh155p and Prp5p.

68 In miRNA-mediated gene silencing, the physical interaction between human Argonaute (hAgo) and

69 ECs and activates calmodulin to facilitate a physical interaction between Kruppel-like factor 2 (KLF2

70 anonical NF-kappaB pathway, which requires a physical interaction between ks-vFLIP and the IKK kinase

71 The physical interaction between low polymeric forms of CSQ1

72 We uncover a direct physical interaction between Magi and the Ras associatio

73 The physical interaction between Malat1 and apoptotic or inf

74 Additionally, we demonstrate physical interaction between MIF and three receptors: CX

75 in newly synthesized viral RNA and feature a physical interaction between mitochondrial membranes and

76 However, the physical interaction between Myosin and actin filaments

77 A network of adhesion molecules mediate this physical interaction between neurons.

78 the peripersonal space (PPS), mediates every physical interaction between our body and the environmen

79 In the presence of SETD6, the physical interaction between PAK4 and beta-catenin is dr

80 We reveal a physical interaction between PDGFRalpha and PDGFRbeta in

81 Immunoprecipitation revealed a physical interaction between PHIP and VCL.

82 Moreover, PCH1 and PCHL facilitate the physical interaction between phyB and PIF1 in vivo to pr

83 Physical interaction between Pph3 and Mec1, mediated by

84 previously that residues not involved in the physical interaction between proteins make important con

85 iled biochemical analysis reveals the direct physical interaction between PRRX1 and FOXM1 proteins th

86 regulated Ser-727 phosphorylation, whereas a physical interaction between RET/PTC3 and STAT1, followe

87 nce energy transfer) assay revealed that the physical interaction between Rho molecules expressed in

88 Together with a physical interaction between RPGR and the C-terminal dom

89 Here, we report a functional and physical interaction between RPS3 and RECQL4 and show th

90 In the described approach, the physical interaction between sets of designed nanopartic

91 (ii) Physical interaction between SIM362-364 and PML II is ne

92 nscript Antisense Intergenic RNA) mediates a physical interaction between Snail and enhancer of zeste

93 These results provide evidence of a physical interaction between specific photosystem II lig

94 This activity requires a physical interaction between Srs2 and Rad51, which stimu

95 Moreover, we show that the physical interaction between TAP2 and TPN is disrupted b

96 Here, we describe a physical interaction between TDP-43, an RNA-binding prot

97 Here, we characterise the physical interaction between TET1 and NANOG using embryo

98 Indeed, we identify a physical interaction between the autoinhibitory N termin

99 y and sensorimotor interface mediating every physical interaction between the body and the environmen

100 r experiments provide strong evidence that a physical interaction between the C-terminal and catalyti

101 Our results demonstrate a direct physical interaction between the C-terminal domains of t

102 ength recombinant BdALMT12, we confirmed the physical interaction between the CBD and CaM.

103 matin conformation capture (3C) identified a physical interaction between the enhancer element contai

104 ow that Hs2st (but not Hs6st1) facilitates a physical interaction between the Fgf17 protein and HS.SI

105 ergies of >/=1 kcal/mol, indicating a close, physical interaction between the ligand and residue 195

106 2X4R in HF and is the first to demonstrate a physical interaction between the myocyte receptor and eN

107 ation of some molecular solute; a long-range physical interaction between the particle and solute mol

108 The physical interaction between the proteins was confirmed

109 A physical interaction between the protomers was confirmed

110 rminal CCT/PF2 domain, which is required for physical interaction between the Ste20 kinases and the N

111 The physical interaction between the two proteins through a

112 ion and degradation and is implicated in the physical interaction between the two proteins.

113 creasing water conductance through AQP1 by a physical interaction between the two proteins.

114 (EC) coupling in skeletal muscle requires a physical interaction between the voltage-gated calcium c

115 Thus, the Cga eRNA mediates the physical interaction between these genomic regions and d

116 e effects correlating with the extent of the physical interaction between these molecules.

117 d mobility similar to BRCA2, which indicates physical interaction between these proteins both before

118 anisotropy nanodisc assays revealed a direct physical interaction between TMEM219 and IL-13Ralpha2-Ch

119 tion experiments, we further demonstrate the physical interaction between Top1p and Sir2p.

120 hagy and observed a functionally significant physical interaction between transcription factor EB (TF

121 t independent of TRPC6 channel activity, the physical interaction between TRPC6 and calpain in the po

122 Coimmunoprecipitation confirmed a physical interaction between TRPV5 and MUC1.

123 ist and presented a structural basis for the physical interaction between TSP-1 and BMP-4.

124 Various methods can provide a readout of the physical interaction between two biomolecules.

125 We subsequently found evidence for physical interaction between UBE3A and MEF2C also in hum

126 The physical interaction between VER2 and TaGRP2 is controll

127 ) complex (or signalosome), which involves a physical interaction between vFLIP and the modulatory su

128 methodology to systematically create binary physical interactions between a query protein and most o

129 nt co-operative gating behaviour mediated by physical interactions between adjacent channel C-termina

130 Genetic and physical interactions between ALB4 and ALB3, and physica

131 ical interactions between ALB4 and ALB3, and physical interactions between ALB4 and cpSRP, suggest th

132 Physical interactions between Beclin-1 and Bcl-2 were in

133 The mapping of the physical interactions between biochemical entities enabl

134 In addition, we observed direct physical interactions between Blm and two telomere-bindi

135 Characterization of physical interactions between BMAL1 enhancers and other

136 Physical interactions between CB1 and D2L were observed

137 rategies used for improving the chemical and physical interactions between cells and biomaterial surf

138 tion capture technologies (e.g., Hi-C) chart physical interactions between chromatin regions on a gen

139 borated by biochemical studies demonstrating physical interactions between Coa6, Cox2, Cox12 and Sco

140 These results indicate both genetic and physical interactions between disease-linked RBPs and DN

141 i-C) allows the genome-wide interrogation of physical interactions between distal DNA regulatory elem

142 Physical interactions between distal regulatory elements

143 ween nuclear structure and function, and the physical interactions between distal regulatory elements

144 Disrupting physical interactions between FAMA and RBR preferentiall

145 iquitylation reaction necessitates transient physical interactions between FBXW11 and its substrates,

146 transcriptionally active genes determined by physical interactions between genes with specific euchro

147 Physical interactions between hyphae and fine roots were

148 ogy will make it possible to investigate how physical interactions between identical DNA molecules co

149 agents not interacting with each other, (ii) physical interactions between inanimate objects, and (ii

150 Physical interactions between molecules are the linking

151 distal tips of microvilli, where they drive physical interactions between neighboring protrusions.

152 Although numerous physical interactions between Par-3 and the Par complex

153 The physical interactions between proteins constitute the ba

154 opology and intracellular localization, (vi) physical interactions between proteins from the database

155 and degradation, as well as insight into the physical interactions between proteins, and between prot

156 d coexpressed recombinant proteins supported physical interactions between PtrCAD1 and PtrCCR2.

157 We identified novel physical interactions between retromer and the Saccharom

158 We identified significant physical interactions between risk regions and their pot

159 icates that such coordination is mediated by physical interactions between subsets of so-called SNARE

160 Direct physical interactions between the APE1-Polbeta, APE1-TDP

161 Moreover, physical interactions between the BBS and ADPKD proteins

162 Even in the absence of direct physical interactions between the binding partners, such

163 Our findings highlight the role of the physical interactions between the cytoskeletal network a

164 These results indicate that physical interactions between the tandem C2 domains of s

165 vely, we investigated whether genetic and/or physical interactions between the two proteins could exp

166 led beating rates of cardiomyocytes, and the physical interactions between these cells increased neur

167 Physical interactions between these receptors have never

168 This highlights the importance of physical interactions between tissues during morphogenes

169 this information, we defined functional and physical interactions between VAPB and proteostasis regu

170 ed by proteins whose structural features and physical interactions can alter the length scale at whic

171 ne transcription, suggesting that SIX1-GATA1 physical interactions contribute to the observed functio

172 layers, accounting for different genetic and physical interactions, each containing thousands of prot

173 A fundamental physical interaction exists across the synapse.

174 A specific physical interaction exists between the Parkinson diseas

175 xperiments, structure-function analysis, and physical interaction experiments argue that Fat negative

176 -immunoprecipitation independently confirmed physical interactions for three proteins in vitro and/or

177 l interaction between FAO and the ETC, their physical interaction has never been demonstrated.

178 pression of PKM1 and PKM2 and their possible physical interaction in cancer cells.

179 sing optical tweezers, we tested the dynamic physical interaction in vivo.

180 ivation-strain model calculations to analyze physical interactions in heteroaromatic azadiene-alkene

181 ne receptors (nAChRs) display functional and physical interactions in many cell types and heterologou

182 d WUS share common targets in vivo and their physical interaction is important in driving downstream

183 el of inhibition of gene expression in which physical interaction is more important than enzymatic ac

184 interact with PCGF1 in a subsequent round of physical interaction mapping experiments.

185 synergistically and possibly through direct physical interactions, molecular mechanisms by which the

186 mis engage with keratinocytes (KCs) in tight physical interactions; moreover, they induce T-cell-medi

187 The resulting high-quality physical interaction network, comprising 77% of targeted

188 Here we characterize the physical interaction of ACT with FHA and provide evidenc

189 Interactome analyses further revealed the physical interaction of cavin-1 and caveolin-1 and their

190 echanisms and functional consequences of the physical interaction of channels with transporters have

191 factors involved in mRNA export disrupts the physical interaction of chromosomal sites with NPCs.

192 Co-IP experiments confirmed the physical interaction of COH1 with RAB6 that preferential

193 By demonstrating a physical interaction of CPR5 with bZIP60 and bZIP28, we

194 mechanism of action revealed a preferential physical interaction of FAU with mutant CFTR, leading to

195 Physical interaction of interacting domains leads to TAL

196 We confirm the genetic and physical interaction of LATE3 and LATE4 and show that th

197 tein interaction analyses suggest the direct physical interaction of LIL3 with POR but not with chlor

198 The physical interaction of Myc with the E-box DNA motif has

199 This evidence, along with strong physical interaction of NAHR breakpoints belonging to th

200 CP) subunit of the F1FO-ATP synthase and the physical interaction of OSCP with amyloid beta (Abeta) i

201 Physical interaction of regulatory elements in three-dim

202 Thus physical interaction of TDG with PCNA through the PIP de

203 ite of esterification is associated with the physical interaction of the major SOAT, acyl-coenzyme A:

204 We provide evidence for the genetic and physical interaction of the prion protein Rnq1 with Sup3

205 The physical interaction of TROY/RKIP was confirmed via co-i

206 namics of the 16p11.2 network by integrating physical interactions of 16p11.2 proteins with spatiotem

207 We first excluded physical interactions of both channels using radioligand

208 formation capture (4C-seq) identified direct physical interactions of elements within 11p13.

209 Determination of the physical interactions of environmental chemicals with ce

210 ation, overall O-GlcNAc levels decrease, and physical interactions of GATA-1 with both OGT and OGA in

211 nt link that integrates biochemical cues and physical interactions of IAMs with the injury microenvir

212 mmunoprecipitation experiments and assessing physical interactions of NFU1 with many [4Fe-4S]-contain

213 STZ diabetic hearts display increased physical interactions of OGA with alpha-actin, tropomyos

214 Many important cellular processes involve physical interactions of proteins.

215 Pull-down experiments also confirm the physical interactions of ScDmc1 with ScRad51 in solution

216 investigate the role of PCGF1, we mapped the physical interactions of the protein under endogenous co

217 on, respectively, providing insight into the physical interactions of this class of RAS variants with

218 and opaque systems according to chemical and physical interactions of water within them.

219 allow an agnostic characterization of these physical interactions on a genome-wide scale.

220 y toward assessing the significance of these physical interactions on enhancing storage capacity and

221 d drugs, proteins, and nanoparticles through physical interactions or be chemically modified to coval

222 Networks formed by physical interactions or homological relationships betwe

223 Because these networks are mainly based on physical interactions, our designs could be expanded to

224 We identified 29 novel physical interaction partners of Spin and focused on the

225 These physical interactions place Usp15 in the vicinity of act

226 nd a temporal one, exhibited both social and physical interaction preference, which, in the temporal

227 The favorable physical interaction properties enable selective treatme

228 Here, we show that CPG2, through a direct physical interaction, recruits endophilin B2 (EndoB2) to

229 This altered physical interaction results in altered loading (i.e., "

230 Genetic and physical interaction studies revealed that ALA3 function

231 We conclude that CaV1.2 Asp-181 anchors the physical interaction that facilitates the CaValpha2delta

232 whereby Hog1 senses arsenic through a direct physical interaction that requires three conserved cyste

233 les containing clustered cis elements and by physical interactions that are documented to occur betwe

234 We examined the physical interactions that stabilize the closed and open

235 Compared with physical interactions, the chemical anchorage results in

236 ation of perturbations in local chemistry or physical interactions through an impact on global dynami

237 the genome reflects a network of permissible physical interactions through which enhancers, promoters

238 ing of polycomb repressive complex 2 through physical interaction, thus maintaining H3K27me3 marks at

239 domain through its KRAB domain, and both its physical interaction to GR and zinc finger domain appear

240 We observed the motor adaptations during physical interactions to be mutually beneficial such tha

241 n of the peptide was essential to facilitate physical interaction via a single binding site involving

242 d by the interplay of structural profile and physical interactions, which demonstrates the potential

243 ate lid of mortalin were necessary for these physical interactions, which is consistent with conventi

244 ry integration by an individual, but require physical interaction with a reactive partner.

245 SWCNT sidewalls, thereby reducing potential physical interaction with algal cells.

246 Here, we show that ERG, through its physical interaction with androgen receptor, induces AR

247 t the Jas domain of JAZ4 is required for its physical interaction with COI1, MYC2 or MYC3, but not wi

248 about how locomotor transitions emerge from physical interaction with complex terrain.

249 gulates ETI and the associated PCD through a physical interaction with cyclin-dependent kinase inhibi

250 an ethylene (ET)-dependent pathway involving physical interaction with different ACC SYNTHASE (ACS) i

251 Physical interaction with DVL is essential for the Wnt i

252 Physical interaction with ERAP2 changes basic enzymatic

253 of ABCB1 was suggested to be regulated by a physical interaction with FKBP42/Twisted Dwarf1 (TWD1),

254 (Sesn-C) modified this motif to accommodate physical interaction with GATOR2 and subsequent inhibiti

255 iates with CFSs in early mitosis through its physical interaction with MUS81 and promotes MUS81-depen

256 ono-ubiquitination of Myosin II promotes its physical interaction with Myosin VIIa, a protein respons

257 nteractor elements" (IEs) involved in direct physical interaction with nucleic acids, proteins, or li

258 he H3K27me3-silencing mark, validating their physical interaction with PRC2 components.

259 disease and yeast genetic screens alter the physical interaction with Prp5p, alter branch region spe

260 tion loop of Myosin II, which is involved in physical interaction with subdomain 1 of actin and in st

261 t7 to be mostly alpha-helical and document a physical interaction with the b6f complex through increa

262 age sensitivity that are best explained by a physical interaction with the channel gates.

263 logenetic analysis, structural similarities, physical interaction with the CMG helicase component SLD

264 uired for transcriptional repression and for physical interaction with the corepressor TOPLESS.

265 proliferative macrophages with a surprising physical interaction with the developing vasculature.

266 ification and protein folding, and undergoes physical interaction with the MAM-associated and ER fold

267 aling function, the mechanism underlying its physical interaction with the membrane remains elusive.

268 ectivity, gating, and pharmacology by direct physical interaction with the pore module.

269 positioning of pol IV foci likely reflects a physical interaction with the RecA* nucleoprotein filame

270 ranscriptional AGO1 functions is provided by physical interaction with the RNA polymerase II transcri

271 PRDM16's repressive properties, mediated by physical interaction with the transcriptional corepresso

272 by facilitating U7-snRNP recruitment through physical interaction with the U7-snRNP-specific componen

273 indicates that their activity relies on the physical interaction with transcription factors (TFs).

274 ping role, we found Nup98 to gain and retain physical interactions with architectural proteins upon s

275 of action of RBM5-AS1 in the WNT pathway via physical interactions with beta-catenin, helping organiz

276 Copurification studies also identified physical interactions with CDC20, BUBR1, and other compo

277 In addition to the physical interactions with cellular membranes, viruses h

278 occupies Ctcf binding sites in vivo and has physical interactions with CTCF and the cohesin subunit

279 to contribute to PUFA enrichment of TAG, for physical interactions with each other under in vivo cond

280 e modulation of gene expression outcomes via physical interactions with effector proteins, which may

281 specific role of calcineurin in coordinating physical interactions with host cells highlights an ance

282 e known also to coordinate solute uptake via physical interactions with K(+) channels and to moderate

283 peptides on K. pneumoniae, along with their physical interactions with K. pneumoniae capsule.

284 Wacky and WAC have conserved physical interactions with mTOR and its regulators, incl

285 sk locus may function as a regulatory hub by physical interactions with multiple genes important for

286 lysis of vertebrate Nab2, ZC3H14, identifies physical interactions with numerous components of the sp

287 that were experimentally determined to have physical interactions with Polycomb repressive complex 2

288 sbO at two conserved amino acids involved in physical interactions with PSII and reduces the binding

289 d51 filament formation during HR through its physical interactions with Rad55-Rad57.

290 K13 may affect RNA processing through direct physical interactions with RNA processing factors and by

291 cterial species with metabolic dependency or physical interactions with S. mutans suffered drastic re

292 centrations of SRC-3 in cells through direct physical interactions with SRC-3, and selectively induce

293 diverse array of cellular processes through physical interactions with substrates and binding partne

294 e channels known and are activated by direct physical interactions with the endoplasmic reticulum Ca(

295 es through sensorimotor feedback produced by physical interactions with the environment.

296 ive regulator of photoperiodic flowering via physical interactions with the red-light receptor phytoc

297 Thus, physical interactions with the vascular endothelium are

298 form vital roles in visual communication and physical interactions within and between species.

299 Three-dimensional physical interactions within chromosomes dynamically reg

300 uenced by alternative cleavage sites and the physical interactions within the membrane.