ライフサイエンスコーパス: phytosterol

1 (P = 0.01; n = 10) after inclusion of 300 mg phytosterols.

2 s of unsaturated fatty acids, phenolics, and phytosterols.

3 product containing fruits, and enriched with phytosterols.

4 ed with natural antioxidants-tocopherols and phytosterols.

5 one betalains, sixteen carotenoids, and five phytosterols.

6 amma-oryzanol, tocotrienols, tocopherols and phytosterols.

7 natural antioxidants in the stabilisation of phytosterols.

8 han 20 carbon atoms, higher hydrocarbons and phytosterols.

9 tribute significantly to the total intake of phytosterols.

10 0.93 (0.86, 1.01; P-trend = 0.16) for total phytosterols, 0.89 (0.82, 0.96; P-trend = 0.05) for camp

11 ith freeze-dried POC, the oil contained more phytosterols (13-fold), tocopherols (6-fold) and squalen

12 g) acids, DRP (160 degrees C for 10 min) for phytosterols (1821.30 mg/kg) and IRP (180 degrees C, 5 m

13 3198mg/100g), fatty acids (1500mg/100g), and phytosterols (192mg/100g) as major components.

14 l was characterised by very high contents of phytosterols (2-2.5 g/100 g).

15 s well as carotenoids (335+/-98mug/100g) and phytosterols (22.1+/-3.9mg/100g).

16 The greatest amount of phytosterols (2852.5mg/100g of oil) was detected in Maha

17 d the presence of tocopherols (86.72 mg) and phytosterols (32.25 mg) in 100 g oil with significant an

18 ils are rich in healthy oleic acid (55-74%), phytosterols (3200-7600mg/kg) and gamma-tocopherol (550-

19 active compounds were identified including 6 phytosterols (34.73-59.48 mg/100 g), 6 triterpenes (30.5

20 cholesterol (p < 0.001) higher than that of phytosterols (35% reduction).

21 total phenols (25.92%), tannin (34.72%), and phytosterol (75.39%).

22 beta-Sitosterol was the dominant phytosterol (80-83%).

23 B-Sitosterol was the dominant phytosterol (80-83%).

24 o bioaccessibility of beta-Cryptoxanthin and phytosterols, a MFGM containing beverage was selected an

25 In order to prevent the photooxidation of phytosterols, a new type of Pickering emulsion was devel

26 Blockade of phytosterol absorption either by therapeutic inhibition

27 Inhibition of phytosterol absorption reduced inflammation and cardiac

28 otypes independently of its role in opposing phytosterol absorption.

29 in mice treated with ezetimibe, which blocks phytosterol absorption.

30 Our previous work identified a link between phytosterol accumulation and cardiac injury in a mouse m

31 is the first to report such toxic effects of phytosterol accumulation in ABCG5/G8 knockout mice.

32 orm a functional complex that limits dietary phytosterol accumulation.

33 The combined use of tocopherols and phytosterols achieved the most effective protection, pro

34 pothesis that a single daily dose of soybean phytosterols added to ground beef will lower plasma TC a

35 As the levels of phytosterols addition were increased in cheese spread fr

36 tes, the firmness of the PCS at 3% and 4% of phytosterols addition were significantly (p<0.05) higher

37 Monthly changes of lipids, fatty acids, phytosterol and alpha-tocopherol in New Zealand brown ma

38 were lower in GSD patients, whereas biliary phytosterol and cholesterol concentrations were elevated

39 C-TOF for their triacylglycerol, tocopherol, phytosterol and fatty acid composition, while oxidative

40 as well as naturally occurring complexes of phytosterol and phospholipid might be therapeutically us

41 Phytosterol and phytostanol contents showed a steep decr

42 ne proteins and suggest that the PM contains phytosterol and sphingolipid-rich lipid domains with a s

43 is review evaluates the relationship between phytosterol and stanol supplementation and cardiovascula

44 ht be used as an indicator for estimation of phytosterol and triterpene contents in Djulis hull.

45 Minor lipids in cereals (such as phytosterols and alkylresorcinols) can be important for

46 previously unknown pathological link between phytosterols and cardiac arrhythmias in the same animal

47 The uptake of intestinal phytosterols and cholesterol into absorptive enterocytes

48 the effect of the most nutritional prevalent phytosterols and cholesterol on APP processing.

49 tored via herbivory and supplementation with phytosterols and cholesterol.

50 for sterols; therefore, they have to consume phytosterols and dealkylate them to cholesterol.

51 genetic condition phytosterolemia overabsorb phytosterols and develop premature atherosclerosis.

52 ates (PS-DHA) may offer both the benefits of phytosterols and DHA, possibly in a synergistic manner.

53 nin, carotenoids, tocopherols, tocotrienols, phytosterols and dietary fiber.

54 ison of serum sterols showed lower levels of phytosterols and higher levels of cholesterol precursors

55 sorder characterized by elevated circulating phytosterols and increased cardiovascular disease risk.

56 Both diets contained phytosterols and less cholesterol compared with a standa

57 ong with high concentrations of isoflavones, phytosterols and minerals that enhance the nutritional v

58 Fifteen phytosterols and one phytostanol were quantified.

59 gamma-oryzanols, tocopherols, tocotrienols, phytosterols and phytic acid.

60 Cholesterol-lowering properties of phytosterols and phytostanols are the main driver for fo

61 The content of phytosterols and phytostanols in margarines changed from

62 ile most of the research has focused on free phytosterols and phytosteryl esters of fatty acids, few

63 or intestinal uptake of both cholesterol and phytosterols and plays a major role in cholesterol homeo

64 ion by GSK2033 increased the accumulation of phytosterols and reduced binding of FXR to the SHP promo

65 anaerobic bacterial degradation of zoo- and phytosterols and shows only little similarity to known p

66 f this work was to coencapsulate echium oil, phytosterols and sinapic acid (crosslinker/antioxidant),

67 Finally, conspicuous amounts of phytosterols and squalene were found.

68 trated that the final extract also contained phytosterols and squalene.

69 Phytosterols and stanols are plant derivatives that comp

70 The doses of phytosterols and the probiotic potential were maintained

71 oxy derivatives dominated among all oxidised phytosterols and their content increased threefold at th

72 Phytosterols and their derivatives have attracted much a

73 aimed to reveal cholesterol metabolites and phytosterols and their relation to stone composition of

74 Fatty acids, phytosterols and tocopherols amounted as the major bioac

75 alth-related compounds, such as polyphenols, phytosterols and tocopherols.

76 by PEF showed total phenolic content, total phytosterols and total tocopherols significantly higher

77 functional ingredients, was used to identify phytosterols and triterpenes from seven inbred lines of

78 surface color that reflected the content of phytosterols and triterpenes.

79 lipids, such as free and conjugated forms of phytosterols and typical phytosphingolipids, such as gly

80 This may be due to parenteral phytosterols and/or the presence of pro-inflammatory med

81 which might contribute to the development of phytosterols and/or triterpenes enriched functional food

82 Plant sterols (phytosterols) and the drug ezetimibe reduce cholesterol

83 s like oryzanols, tocopherols, tocotrienols, phytosterols, and dietary fibers.

84 ent on the sensory quality, aroma compounds, phytosterols, and phytosterol oxidation products (POP) i

85 ods (ie, plant protein, nuts, viscous fiber, phytosterols, and plant monounsaturated fats) shown to i

86 Ascorbate (vitamin C), phytosterols, and several phenolic anti-oxidants such as

87 Phytosterols are cholesterol-like molecules found in all

88 Phytosterols are effective in lowering low-density lipop

89 Phytosterols are elevated in neonatal cholestasis, but t

90 In general, phytosterols are less amyloidogenic than cholesterol.

91 Phytosterols are naturally occurring cholesterol plant e

92 Phytosterols are plant sterols structurally similar to c

93 Phytosterols are primary plant metabolites that have fun

94 Current literature suggests that phytosterols are safe when added to the diet, and measur

95 Phytosterols are structurally similar to cholesterol and

96 Plant-derived sterols, often referred to as phytosterols, are important constituents of plant membra

97 Plant sterols, or phytosterols, are very similar in structure to cholester

98 phasizes the potential importance of dietary phytosterols as adjunctive therapy for the treatment of

99 matis was not able to utilize cholesterol or phytosterols as carbon sources implying that this ATPase

100 d bioactive compounds (e.g., polyphenols and phytosterols) as compared to cereal grains.

101 ates the potential of campesterol, a natural phytosterol, as an ERalpha inhibitor for breast cancer.

102 ocado oil was richer than olive oil in total phytosterols at time 0h (339.64; 228.27mg/100g) and at 9

103 with control, ezetimibe alone, and ezetimibe+phytosterols averaged 129 mg/dL (95% CI, 116 to 142), 10

104 obably understates the true effectiveness of phytosterols because it does not account for those natur

105 duces Delta(24,28) double bonds required for phytosterol biogenesis as well as Delta(24,25) double bo

106 emethylates obtusifoliol, an intermediate of phytosterol biosynthesis and 4-desmethyl-24,25-dihydrola

107 ed by comparing normalization methods of the phytosterol biosynthesis gene GhHYDRA1 in response to ap

108 The transcriptional regulation of SMT in phytosterol biosynthesis is discussed.

109 , disturbed carbohydrate metabolism, reduced phytosterol biosynthesis, and delayed energy regeneratio

110 benthamiana SQUALENE SYNTHASE, a key gene in phytosterol biosynthesis, not only compromised nonhost r

111 ransferase (SMT), a rate-limiting enzyme for phytosterol biosynthesis.

112 e protein, CB5LP, as a critical component of phytosterol biosynthesis.

113 s in vivo, suggesting that dietary intake of phytosterol blends mainly containing stigmasterol might

114 Analysed margarines contained four phytosterols: brassicasterol, campesterol, sitosterol, a

115 rce of phytosterols; corn oil contains 0.77% phytosterols by weight.

116 troscopy experiments showed that among major phytosterols, campesterol exhibits a stronger ability th

117 nlinear associations were observed for total phytosterols, campesterol, and beta-sitosterol: the risk

118 Phytosterols can also be dispersed in water after emulsi

119 Phytosterols can be emulsified with lecithin and deliver

120 e low intestinal bioavailability of purified phytosterols can be increased by formulation with lecith

121 Cholesterol and phytosterols can be oxidised under heating conditions to

122 ls: (i) a bulk membrane requirement in which phytosterols can substitute for cholesterol and (ii) oth

123 The phytosterol capsules produced in the electrospraying pro

124 aim of this study was to analyse contents of phytosterols, carotenoids, tocochromanols and fatty acid

125 ribution differs in plants and animals, with phytosterols commonly found in plants whereas most anima

126 The phytosterol composition of whole pecan kernel was quanti

127 and mutant should permit the manipulation of phytosterol composition, which will help elucidate the r

128 erol, and campesterol were the most abundant phytosterol compounds at all ripening stages.

129 Phytosterols comprising < 1% of commercial corn oil subs

130 uence of several factors, especially fat and phytosterols concentration, on the behavior of margarine

131 Elevated plasma phytosterol concentrations are an untoward effect of par

132 entation produces minimal increases in blood phytosterol concentrations in humans.

133 On PN days 7 and 14, plasma phytosterol concentrations were highest in the S group a

134 lation between phytosterol intake and plasma phytosterol concentrations; however, cholestasis was rar

135 Increasing the aggregate amount of phytosterols consumed in a variety of foods may be an im

136 ut the possibility to effect rapid screen of phytosterol containing in complex media have been shown.

137 In PNAC, phytosterol containing PN synergizes with intestinal inj

138 In PNAC, phytosterol containing PN synergizes with intestinal inj

139 The phytosterol content in the fastest growing angiosperm, W

140 s and potential heterogeneity by nut type or phytosterol content, are not well established.

141 al characteristics (natural antioxidants and phytosterols content, in vitro antioxidant capacity and

142 al characteristics (natural antioxidants and phytosterols content, in vitro antioxidant capacity and

143 Each subject received a phytosterol-controlled diet plus (1) ezetimibe placebo+p

144 table oils are the richest dietary source of phytosterols; corn oil contains 0.77% phytosterols by we

145 he transition from pre-veraison to veraison, phytosterols decreased in all tissues, in both years, ap

146 The high-phytosterol diet was extremely toxic to the ABCG5/G8 kno

147 Phytosterols displace cholesterol from intestinal micell

148 ive plant tissues, few studies have examined phytosterol diversity in pollen.

149 declined significantly only with the highest phytosterol dose (-8.9 +/- 2.3%); a trend was observed w

150 Phytosterols effectively reduce LDL-cholesterol when giv

151 Phytosterol esters dissolved in food fat reduce LDL-chol

152 To determine the significance of phytosterol exclusion from the body, we fed wild-type an

153 Phytosterol feeding in human clinical trials has had gen

154 by-products showed B-sitosterol as the major phytosterol, followed by B-campesterol.

155 rol placebo, and (3) 10 mg/d ezetimibe+2.5 g phytosterols for 3 weeks each.

156 nostructured lipid carriers (NLCs) with free phytosterols (FP) using conventional fats and oils.

157 components, such as triacylglycerols (TAGs), phytosterols, free fatty acids (FFA), and their respecti

158 We tested the hypothesis that removing phytosterols from corn oil would increase cholesterol ab

159 nd appear to remove unwanted cholesterol and phytosterols from the enterocyte.

160 hat strong specific interactions between the phytosterols from the non-purified oil and the saponins

161 Co-incubation with phytosterols further reduced expression of these genes.

162 one) or treatment (ground beef with 2.7 g of phytosterols) group.

163 The potential effectiveness of phytosterols has been improved in several ways.

164 Consumption of phytosterols has been suggested to positively affect hum

165 Phytosterols have attracted much attention in recent yea

166 In the present study phytosterols (have hypocholesterolemic effect) have been

167 idence of 7-dehydrostigmasterol or any other phytosterol in Acanthamoeba.

168 ol was the most important and representative phytosterol in both oils ( approximately 127 mg/100 g oi

169 pid determination of the distribution of the phytosterols in aqueous food matrixes.

170 Preferential solubility of phytosterols in ethanol allowed effective elimination of

171 A novel method for the measurement of total phytosterols in fortified food was developed and tested

172 rovides a new means for studying the role of phytosterols in hematologic diseases and testing therape

173 Single meal studies show that phytosterols in intact foods are bioactive at doses as l

174 Dietary phytosterols in moderate and high doses favorably alter

175 ions, raising doubts about the importance of phytosterols in natural diets and supplements.

176 re work will focus on the better delivery of phytosterols in natural foods and supplements and on fur

177 imultaneous analysis of tocopherols and free phytosterols in nuts was developed.

178 arch does not support an association between phytosterols in parenteral lipid solutions and total par

179 in the production of ergosterol in fungi or phytosterols in plants.

180 eceptor liver receptor homolog 1 (LRH-1) and phytosterols in PNAC.

181 e was to study the effect of 5 LEs on plasma phytosterols in preterm infants.

182 The role of phytosterols in preventing CAD warrants further investig

183 lied to the analysis of tocopherols and free phytosterols in samples of almonds, cashew nuts, hazelnu

184 ferential involvement of free and conjugated phytosterols in the formation of ordered domains and sug

185 Phytosterols in the LEs and in plasma (on postnatal day

186 ion of sugars, fatty acids, amino acids, and phytosterols in the mutant endosperm, suggesting that in

187 le method to characterize the composition of phytosterols in vegetable oils and enriched margarines.

188 cate that cholesterol oxidase can metabolize phytosterols in vivo when produced cytosolically or when

189 e RVA cheese melt viscosity index of all the phytosterols incorporated cheese spread samples were sig

190 All the phytosterols incorporated cheese spread samples were sig

191 Total phytosterols increased with the higher combination of pr

192 Both ezetimibe and phytosterols inhibit cholesterol absorption.

193 A moderate phytosterol intake (459 mg/d) can be obtained in a healt

194 he associations between total and individual phytosterol intake and CAD risk in United States health

195 g routine PN, we found a correlation between phytosterol intake and plasma phytosterol concentrations

196 Associations between phytosterol intake and the risk of CAD, such as nonfatal

197 cipants (N range between 11,983 and 22,039), phytosterol intake was inversely associated with plasma

198 Phytosterol intakes (diet plus supplements) averaged 59,

199 We evaluated the effects of 3 phytosterol intakes on whole-body cholesterol metabolism

200 tive to the 59-mg diet, the 459- and 2059-mg phytosterol intakes significantly (P < 0.01) increased t

201 n the S group had significantly higher total phytosterol intakes than did the other study groups.

202 The initial step in the conversion of the phytosterol intermediate cycloartenol to the 24-alkyl st

203 ues reveals that incorporation of C-24 alkyl phytosterols into LNPs (eLNPs) enhances gene transfectio

204 The effects of incorporating phytosterols into lower-fat foods on the plasma lipids o

205 n most of the cases, the most representative phytosterol is B-sitosterol, followed by campesterol or

206 n most of the cases, the most representative phytosterol is beta-sitosterol, followed by campesterol

207 onstrate that the combination of saponin and phytosterols is a powerful new approach to structure oil

208 thesis that the combination of ezetimibe and phytosterols is more effective than ezetimibe alone in a

209 polyunsaturated fatty acids, tocopherols and phytosterols is presented for two close species of Pluke

210 The use of phytosterols is restricted due to their high melting tem

211 intake of sterols, including cholesterol and phytosterols, is probably not relevant.

212 , much less is known about the effect of low phytosterol levels in the natural diet.

213 In the follow-up study, serum phytosterol levels were significantly lower even before

214 increase in atherosclerotic risk from serum phytosterol levels.

215 sitosterol, with dramatically reduced plasma phytosterol levels.

216 were formed only at monoacylglycerol:native phytosterol (MAG:NPS) ratios of 10:0, 7:3 and 5:5.

217 t in healthy diets, increasing the intake of phytosterols may be a practical way to reduce coronary h

218 g-term intake of total and major subtypes of phytosterols may be associated with a modest reduction i

219 ree test meals, suggesting that natural food phytosterols may be clinically important.

220 In humans, phytosterols may promote liver injury in parenteral nutr

221 ion of LRH-1 and downstream genes may affect phytosterol-mediated antagonism of FXR signaling in the

222 and validation of a new ultrasound assisted phytosterol method through analysis of response surface

223 mes), nuts and seeds, viscous fiber sources, phytosterols (mg/day), and plant monounsaturated fat sou

224 For these reasons, the phytosterol mixture was encapsulated by electrospraying.

225 The phytosterol mixture was two-thirds esterified and one-th

226 s nutrients, including lignans, tocopherols, phytosterols, natural antioxidants, and bioactive compou

227 ug g(-1) gamma-oryzanols, ND-12655 mug g(-1) phytosterols, ND-3189 mug g(-1) squalene, ND-105.3 mug g

228 the coconut and sunflower oil controls, with phytosterol oleogelators exhibiting a pro-oxidant effect

229 ogels at an equivalent mass basis of 20 wt%, phytosterol oleogels exhibited greater hardness (5.9 N)

230 However, the effects of different intakes of phytosterol on cholesterol metabolism are uncertain.

231 THP-1 cells exposed to lipopolysaccharides, phytosterols, or both resulted in enhanced elevation of

232 quality, aroma compounds, phytosterols, and phytosterol oxidation products (POP) in stored plant oil

233 tive substances (TBARS), malondialdehyde and phytosterol oxidation products (POPs) were evaluated as

234 tability was analysed from the production of phytosterol oxidation products (POPs).

235 The total content of phytosterol oxidation products in samples ranged from 96

236 to modulate their protective effect against phytosterols photooxidation.

237 l-controlled diet plus (1) ezetimibe placebo+phytosterol placebo, (2) 10 mg/d ezetimibe+phytosterol p

238 o+phytosterol placebo, (2) 10 mg/d ezetimibe+phytosterol placebo, and (3) 10 mg/d ezetimibe+2.5 g phy

239 little is known about the smaller amounts of phytosterols present naturally in food.

240 duced proportionally to the concentration of phytosterols present.

241 y correlated with growth processes requiring phytosterol production.

242 quantitative and qualitative alterations in phytosterol profiles.

243 The best flavonoid and phytosterol profle was obtained at 20 degrees C/55 % RH,

244 The consumption of omega-3 fatty acids and phytosterol promotes the reduction of cholesterol and tr

245 viding a dual functional delivery system for phytosterols protection.

246 rulic acid derivatives (p > 0.05), and total phytosterols ranging from 8.76 to 13.17 mug/g.

247 Recent animal studies suggest that phytosterols reduce atherosclerosis in the Apo-E deficie

248 Phytosterols reduce cholesterol and low-density lipoprot

249 plementing the diet with large quantities of phytosterols reduces cholesterol absorption and LDL-chol

250 Phytosterols regulate cell membrane fluidity and are pre

251 imized in mixture design as responses of the phytosterol release, minimum in the model stomach and ma

252 Whereas serum levels of phytosterols represent surrogate markers for intestinal

253 ed a pathological mechanism whereby elevated phytosterols result in inflammation and cardiac fibrosis

254 that the presence of high concentrations of phytosterols seems to have an antioxidant effect, since

255 ons of phytonutrients including carotenoids, phytosterols, squalene and vitamin E than PO, postulatin

256 D spaghetti were significantly enriched with phytosterols, squalene, carotenoids, tocochromanols and

257 nalytical method of tocols, gamma-oryzanols, phytosterols, squalene, cholecalciferol and phylloquinon

258 However, only one phytosterol, stigmasterol, reduced Abeta generation by (

259 Phytosterol supplementation of 2 g/d is recommended by t

260 Phytosterol-supplemented ground beef effectively lowers

261 Consumption of phytosterol-supplemented ground beef lowered plasma TC a

262 Consumption of phytosterol-supplemented margarine lowers total plasma c

263 ferase (SMT2) genes governing the pattern of phytosterols synthesized in higher plants have been stud

264 Concerning phytosterols, the total amount reached 1061.45 mg/100 g

265 An ethnic gradient in the ratios of phytosterols to cholesterol precursors was apparent (Ger

266 The ratios of phytosterols to cholesterol precursors were lower in GSD

267 The addition of phytosterols to ezetimibe significantly enhanced the eff

268 Total phytosterols, tocols, flavonoids and rutin content were

269 Phytosterols, tocopherols and carotenoids contents were

270 d and validated for simultaneous analysis of phytosterols, tocopherols and lutein (a carotenoid) in s

271 RR total contents of phytosterols, tocopherols, carotenoids and phenolics wer

272 phenolic compounds, carotenoids, betalains, phytosterols, tocopherols, etc.

273 Fatty acids (FA), phytosterols, tocopherols, phenolic compounds, total car

274 ed the effects of the intestinal cholesterol/phytosterol transporter inhibitor ezetimibe added to cho

275 , total vitamin E, certain simple phenolics, phytosterols, triterpenoids, and anthocyanins one day ea

276 ive carbohydrates and proteins, polyphenols, phytosterols, vitamins, carotenoids, and minerals.

277 The most abundant phytosterol was beta-sitosterol (974-1494 mg/kg) followe

278 The main phytosterol was beta-sitosterol, followed by stigmastero

279 nduced by exposure to lipopolysaccharides or phytosterols was reduced significantly, which was associ

280 When corn oil phytosterols were added back to sterol-free corn oil at

281 ter the completion of heating, the losses of phytosterols were analysed, as well as the contents of b

282 tocopherols, whereas the most representative phytosterols were beta-sitosterol and stigmasterol.

283 Betaxanthins, carotenoids, and phytosterols were detected in all cultivars, mainly in R

284 The surface activities of phytosterols were examined using the pendant drop techni

285 naringin, and narirutin, but carotenoids and phytosterols were not detected.

286 The extraction and washing of phytosterols were performed using food-grade solvents.

287 Cholesterol and several phytosterols were profiled finding high cholesterol conc

288 Oxidative changes of phytosterols were recently studied in vegetable oils and

289 Free and esterified phytosterols were removed from corn oil on a kilogram sc

290 s (emulsions, oil bodies and oil enriched in phytosterols) were determined.

291 ffering in the concentration of both fat and phytosterols, were heated at 180 degrees C.

292 nted a significant content of flavonoids and phytosterols, whereas almond-based nanosuspensions conta

293 phenolics, carotenoids, biogenic amines and phytosterols, which are highly desirable in the diet as

294 ility of stigmasterol, a common food-derived phytosterol with anti-atherosclerotic potential, to prev

295 Esterification of phytosterols with DHA may render improved physiochemical

296 Esterification of phytosterols with long-chain fatty acids increases fat s

297 ted on phytosteryl phenolates, the esters of phytosterols with phenolic acids.

298 Conjugation of phytosterols with sinapic or vanillic acid rendered high

299 Phytosterols yield was 8.5 % at 85 % purity.

300 Phytosterols yield were 8.7 +/- 0.2 % at 86 % purity and