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1 e two mechanical drumheads with masses of 70 picograms.
2 5 min), an excellent detection limit (a few picograms), a large linear dynamic range (>4 orders of m
3 resent work describes a method to quantitate picogram amounts of 14,15-EET enantiomers by capillary e
4 ed in this study enabled the quantitation of picogram amounts of cer-PE containing both unsaturated d
8 bined T-cell infusion, a single injection of picogram amounts of NGR-TNF, a tumor vessel-targeted TNF
10 ine mRNA copies of eight ERalpha isoforms in picogram amounts of total RNA from clinical samples.
11 genomic DNA, exponential amplification from picogram amounts, conversion of misincorporations to mis
12 ry mediator lipoxin A4 was detectable in low picogram amounts, using a novel fluorescence-based detec
14 ence from the chloroplasts, at approximately picogram and subcellular levels by probing inherent mole
15 Here, we utilize microfluidics to isolate picogram and subpicogram mRNA templates, as well as to s
18 2-10B4-derived PG, but not glycoproteins and picogram concentrations of recombinant human interleukin
21 separation for all PAH isomers and with low picogram detection limits on column for all analytes usi
23 s spectrometric method was developed for low-picogram detection of an ergot alkaloid, cabergoline, in
25 ion has been shown to be blocked by very low picogram doses of okadaic acid indicating that inhibitio
28 ed with limits of quantification inferior to picograms for the majority of analytes (0.05-125 pg) and
29 hocyanin cyanidin 3-glucosylrutinoside (2339 picograms/gram of tissue) was detected in bladder, follo
32 renylmethyl esters of PGF(2alpha) isomers at picogram level are complicated by numerous interfering p
33 ge can be adjusted and detection limits at a picogram level can be easily achieved for all n-alkanes.
34 solute quantification method and demonstrate picogram level quantification of prostate-specific antig
35 order (tertiary/quaternary) structure at the picogram level, which is undetectable using conventional
40 cterized hundreds of intact proteoforms from picogram-level cell lysate samples and showed promise fo
41 le sensitive and selective measurements with picogram-level limits of detection (i.e., under 15 ppt i
42 the potential of this approach by detecting picogram levels of a liver-specific miRNA from rat liver
57 tches for the selective assay of fentanyl at picogram/milliliter concentration levels from drug-of-ab
58 outcome measure was PGE-2 concentrations in picograms/milliliter and pupil diameter in millimeters.
59 s (given as geometric mean concentrations in picograms/milliliter) of interleukin-6 (IL-6; 485.2 vers
60 d directly via electrophoretic separation of picogram-nanogram levels of total RNA isolated from mult
62 d flagellar preparations (having less then 1 picogram of LPS/mug) was significantly reduced compared
64 ed detection enable imaging/visualization of picograms of DNA present in a microliter of an unprocess
65 NA profiles to be obtained from only tens of picograms of DNA, corresponding to a few cells, even for
67 gh levels of amplification from as low as 50 picograms of mRNA while offering a dynamic range of over
68 selective ion monitoring mode, allowing for picograms of neurosteroids to be quantified from biologi
69 idic-FCS platform is accomplished using only picograms of protein and DNA samples and less than 1 h t
71 ell line and human tissue samples containing picograms of starting material, which is an order of mag
74 e the absolute amounts of target proteins at picogram or sub-picogram levels per nanogram of cell lys
77 prevented routine quantification in the low picogram per milliliter (parts per trillion, ppt) range
79 sensitive assay for I in human plasma at low picogram per milliliter concentrations using LC/MS/MS wi
85 of detection (LODs) were found to be in the picogram per milliliter to nanogram per milliliter range
87 GFAP level (median, interquartile range; picogram per millilitre) was only increased in symptomat
90 ents, limits of detection in the hundreds of picograms per liter for metals in solution have been obt
91 by determining amounts of MCLR down to a few picograms per liter with an automated array biosensor an
92 volunteers show a large disparity from a few picograms per milliliter (pg/ml) to several nanograms pe
93 ograms per milliliter for p24 antigen, 10.96 picograms per milliliter for anti-p24 antibody, and 1259
94 lated analytical limits of detection of 5.88 picograms per milliliter for p24 antigen, 10.96 picogram
95 The detection limits (3sigma) in the tens of picograms per milliliter level for the elements studied
96 cipants with IPF, BALF MIF greater than 4000 picograms per milliliter was associated with increased m
98 as found with concentrations in the range of picograms per milliliter, suggesting the combustion of c
101 l at diagnosis (median, interquartile range; picograms per millilitre) was significantly increased in
102 demonstrate the limit of detection of a few picograms per square millimeter of surface-bound molecul
104 nalytical method to quantify the drug at low picogram-per-milliliter concentrations in biological mat
106 sterone concentrations declined to less than picograms-per-milliliter levels and remained suppressed
109 ification assay allowed the determination of picogram quantities (1.2 mug/L) of protein, and the cell
110 requires extremely small amounts of protein (picogram quantities and nanoliter volumes) and is easily
111 ical polarimetry measurements, thus allowing picogram quantities of adsorbed molecules to be characte
113 lymerase chain reaction (DOP-PCR) to amplify picogram quantities of human genomic DNA for the purpose
115 ts the generation of cDNA libraries from sub-picogram quantities of RNA robustly, efficiently and rep
117 ition of oxygenation could be determined for picogram quantities of underivatized monohydroxy fatty a
119 evaluated and found to be detectable in the picogram range using a benchtop mass spectrometer and in
121 imits for most neurosteroids were in the low picogram range with the exception of progesterone and di
122 ode, yielding limits of detection in the low picogram range, particularly when analyzed from a glass
123 ment in sample amounts in the subnanogram to picogram range; among those are nuclear forensics, nucle
124 ry good sensitivity (detection limits in the picogram regime are reported for several test compounds
126 very and signal-to-noise ratio, we developed picogram-scale m(6)A RNA immunoprecipitation and sequenc
131 DNA down to a mass of human genomic DNA (5.5 picograms) that is roughly equal to the mass in a single
132 This system is used for the analysis of picogram to femtogram amounts of E. coli digests; for ex
141 (VI)), can be quantified down to 7.3 and 8.3 picogram total Se, respectively, in an overall analytica