ライフサイエンスコーパス: piglet

1 a wedding meal that included a spit-roasted piglet.

2 d compared with LGG-colonized or uncolonized piglets.

3 et-dependent bacterial succession process in piglets.

4 tion and immunity using neonatal gnotobiotic piglets.

5 n of the gut microbiota in the early life of piglets.

6 ere enteric disease particularly in neonatal piglets.

7 mesenteric lymph nodes of 40% of challenged piglets.

8 was assessed in ligated intestinal loops in piglets.

9 oronavirus causing lethal watery diarrhea in piglets.

10 in vivo model to study oral SS2 infection in piglets.

11 d with neonatal and post-weaning diarrhea in piglets.

12 coronavirus that causes diarrhea in nursing piglets.

13 ed in vitro with in vivo data collected from piglets.

14 the study (p = 0.002) compared with control piglets.

15 ovascular performance in asphyxiated newborn piglets.

16 nd mortality rates in humans and gnotobiotic piglets.

17 ing the resuscitation of asphyxiated newborn piglets.

18 e failure in sows and respiratory disease in piglets.

19 Twenty-four newborn (1-4 days old) piglets.

20 her VirHRV fecal titers in nonvaccinated VAD piglets.

21 nd high mortality compared to BBG-challenged piglets.

22 uce myocardial injury in asphyxiated newborn piglets.

23 ulation compared to postarrest, normothermic piglets.

24 flow after fluid percussion brain injury in piglets.

25 rcent cerebrovasodilation in male and female piglets.

26 y rate associated with infection of neonatal piglets.

27 created by graded hemorrhage in anesthetized piglets.

28 d its role in PEDV pathogenicity in neonatal piglets.

29 on of the virus from carrier sows to contact piglets.

30 nd water, compared with tissues from control piglets.

31 rus (PEDV) causes high mortality in neonatal piglets.

32 of the mutants were evaluated in gnotobiotic piglets.

33 with reduced virus shedding and mortality in piglets.

34 A from persistently infected sows to contact piglets.

35 diarrhea and resulting in high mortality in piglets.

36 thermogenic capacities of newborn wild boar piglets.

37 growth and plasma D-xylose concentration in piglets.

38 l of gastric eosinophil in peanut-sensitized piglets.

39 tal death and respiratory disease in newborn piglets.

40 by Firmicutes in asymptomatic and diarrheal piglets.

41 iglets when compared to those of the healthy piglets.

42 ighly virulent PEDV strain PC22A in neonatal piglets.

43 igher in EcN-colonized than in LGG-colonized piglets.

44 Piglets (1-4 d old, weighing 1.4-2.5 kg).

45 Thirty-six piglets (1-4 days old, weighing 1.4-2.5 kg) were acutely

46 veloped moderate gastritis compared to naive piglets (1.5 vs 1.0, median score).

47 opulmonary resuscitation was provided to ten piglets (10.7 +/- 1.2 kg) for 18 mins as six 3-min epoch

48 ings were supported by the fact that contact piglets (11/44) born to persistently infected sows were

49 toms in 9 of 10 animals when it was given to piglets 24 h after bacterial challenge and in 5 of 9 ani

50 was significantly reduced in EPIT vs placebo piglets (61.4 +/- 16.3 vs 105.9 +/- 25.6 ng/mL, P < .01)

51 air trapping more frequently than wild-type piglets (75% vs. 12.5%, respectively).

52 Fourteen piglets 8 weeks of age underwent atrioventricular node a

53 Twenty-eight 4-week-old female piglets (8-11 kg).

54 compounds by intravenous and oral routes in piglet, a known valid model for investigating oral TK.

55 Conversely, 100% of piglets administered only anti-TcdA developed severe GI

56 and attenuates myocardial injury in newborn piglets after asphyxia-reoxygenation.

57 urthermore, whole-body PET scans of 5 female piglets (age +/- SD, 44 +/- 3 d; weight +/- SD, 13.7 +/-

58 feeders of weaned pigs significantly reduced piglet aggression by 30% and tended to increase feeding

59 surface liquid (ASL) collected from newborn piglets and ASL on cultured airway epithelia.

60 re also remarkably increased in asymptomatic piglets and diarrheal piglets when compared to those of

61 faecal maternal semiochemicals that attract piglets and evaluate their effects on piglets at weaning

62 suis is a significant cause of mortality in piglets and growing pigs worldwide.

63 multicomponent maternal signal that attracts piglets and has a calming effect at weaning.

64 ng carbon dioxide pneumoperitoneum in 6 male piglets and maintaining PPP at 25 mmHg, CVP was measured

65 arrants further evaluation in sows and their piglets and may be used as a platform for further optimi

66 le toxin B (TcdB) in sera and body fluids of piglets and mice exposed to C. difficile to investigate

67 Therefore, we used newborn wild-type piglets and piglets with cystic fibrosis to assess air t

68 4.3 +/- 3.1 kg) were obtained up to 236 min (piglets) and 355 min (humans) after injection of 186.6 +

69 On the basis of mouse, piglet, and human kinetic data, the projected human ED o

70 5 muSv/MBq in mice, 14.7 +/- 0.7 muSv/MBq in piglets, and 23.4 +/- 0.4 muSv/MBq in humans.

71 robiota along the length of the intestine of piglets, and determined the effect of SUCRAM supplementa

72 2-specific antibody is sufficient to protect piglets, and possibly humans, against STEC strains that

73 Piglets are attracted to maternal faeces early in life.

74 We conclude that piglets are highly susceptible to shigellosis, providing

75 n dynamics were recapitulated in gnotobiotic piglets as they transitioned from exclusive milk feeding

76 Resection of approximately 90% of the IPP in piglets at birth did not alter Ig levels in serum and se

77 ttract piglets and evaluate their effects on piglets at weaning.

78 For piglets, Bacteroidetes, the dominant bacteria in healthy

79 Data of piglet birth weight and survival show that the presence

80 multiple regression and apply it to data on piglet birth weight and survival.

81 trait, thus, reduction in the variability of piglet birth weight to improve the sow prolificacy is po

82 Piglet birth weight variability, a trait also known as t

83 allocation (maternal investment measured as piglet birth weight/litter weight) was statistically sig

84 on, preliminary data suggested that suckling piglets born by a sow immunized with the pLT(192):pSTa(1

85 effectively provides a fourfold increase in piglets born per oocyte collected.

86 ors in 200 microm thick tissue sections from piglet brain.

87 s in activation of Src kinase in the newborn piglet brain.

88 ostering model with an obese typical Chinese piglet breed and a lean Western breed was used to identi

89 During the suckling period until day 14, the piglet breed and the nursing mother lead to increasing d

90 mage was observed in mitochondria of control piglets but attenuated in that of cyclosporine (10 mg/kg

91 ry low in fetal IPP and the IPP of germ-free piglets but increased 3- to 5-fold after colonization.

92 al signs and pathological lesions in newborn piglets, but they are presumed to be antigenically disti

93 hemodynamic effect of 10% or 20% lean during piglet cardiopulmonary resuscitation.

94 can have mortality rates approaching 100% in piglets, causing serious economic impact.

95 ately 37 nM in smooth muscle cells of intact piglet cerebral arterioles.

96 cterized in gnotobiotic mice and gnotobiotic piglets colonized with age- and growth-discriminatory ba

97 lso higher in ventilator-induced lung injury piglets compared with control piglets, whereas regions s

98 ere higher in ventilator-induced lung injury piglets compared with controls animals.

99 and oxidative stress in doxycycline-treated piglets compared with controls.

100 o chronotropic effect in doxycycline-treated piglets compared with controls.

101 This piglet cross-fostering model is a useful tool for studyi

102 Piglets developed acute diarrhea, anorexia, and dehydrat

103 ejuni successfully established infection and piglets developed an increased temperature with watery d

104 Following oral intake of PPE, sensitized piglets developed moderate gastritis compared to naive p

105 After bronchoalveolar lavages, piglets developed respiratory distress syndrome.

106 We produced three piglets devoid of all cell surface class I proteins.

107 stent with predictions, males performed more piglet directed play than females.

108 FPI were greater in male compared to female piglets during normotension which was blunted by SNP.

109 egatively correlated with the mean growth of piglets during sucking.

110 ensitive to ionizing radiation than non-SCID piglets, eliminating the RAG1 and RAG2 genes.

111 roles of tPA and ERK during/after injury in piglets equipped with a closed cranial window.

112 While the icPEDV-infected piglets exhibited clinical disease, the icPEDV-mut4-infe

113 CG-challenged piglets experienced severe disease accompanied by early

114 ted the efficacy of MMV665917 in gnotobiotic piglets experimentally infected with Cryptosporidium hom

115 Sixteen 7-day-old healthy piglets fed a milk replacer were randomly allocated to o

116 However, in the piglet feed-challenge experiment, only the piglets recei

117 rochalcone (NHDC) and saccharin] included in piglets' feed reduces incidence of enteric disease.

118 Experiments were carried out in piglets first sensitized by three intra-peritoneal injec

119 t of autoregulation during hypotension after piglet fluid percussion brain injury (FPI).

120 mitochondrial injury in asphyxiated newborn piglets following resuscitation.

121 s and the number of both total and live-born piglets for parturition.

122 Piglets from a line of Yorkshire pigs at Iowa State Univ

123 dy alone or with anti-TcdA protected 100% of piglets from development of systemic CDI and minimized G

124 VNA-Stx treatment is effective in protecting piglets from fatal Stx2-mediated CNS complications follo

125 oclonal antibodies (HuMAbs) protect mice and piglets from fatal systemic complications of Stx2.

126 sfully obtained from the small intestines of piglets from sow farms in Indiana and Iowa, respectively

127 The piglet had been stuffed with a raw stuffing partly made

128 ree-choice preference assessment showed that piglets had a preference for a feeder sprayed with a sol

129 rterial hypotension, postarrest, hypothermic piglets had a significant decrease in the perfusion pres

130 Pre-weaning, 101 piglets had access to a neighbouring pen from ~ 15 days

131 Liver tissues from MYO5B(P663L) piglets had alterations in bile salt export pump, a tran

132 Hypoxic piglets had cardiogenic shock (cardiac output 40% to 48%

133 Hypoxic piglets had cardiogenic shock (cardiac output 58% +/- 1%

134 After treatment with ciprofloxacin, infected piglets had diarrhea and the severe fatal neurological s

135 , 88% and 100% TC-PC177- and mock-inoculated piglets had diarrhea following challenge, respectively,

136 Doxycycline-treated piglets had lower myocardial matrix metalloproteinase-2

137 sues and derived enteroids from MYO5B(P663L) piglets had reduced apical levels and diffuse subapical

138 animals grew and developed normally, and SF piglets had several health benefits (eg, increased bone

139 rus (PEDV) causes high mortality in neonatal piglets; however, effective and safe vaccines are still

140 h motifs can reduce the virulence of PEDV in piglets.IMPORTANCE Many coronaviruses (CoVs) possess con

141 ng of the intestinal contents of a diarrheic piglet in Vero cell culture.

142 Anti-A antibodies developed in naive piglets in a kinetic pattern analogous to human infants;

143 improves the recovery of asphyxiated newborn piglets in comparison with coordinated 3:1 resuscitation

144 hemodynamic recovery in asphyxiated newborn piglets in comparison with standard coordinated 3:1 resu

145 individual submucosal glands from 1-day-old piglets in situ in explanted tracheas, using optical met

146 ed systemic-to-pulmonary shunting in growing piglets induces PH with biventricular remodeling and myo

147 We conclude that piglets infected with C. difficile mimic many of the key

148 t systemic administration of alpha-GalCer to piglets infected with pandemic A/California/04/2009 (CA0

149 allenged with Stx2 and protected gnotobiotic piglets infected with STEC from fatal systemic intoxicat

150 as found to have diminished virulence in the piglet infection model.

151 ntly evaluated clinically in the gnotobiotic piglet infection model.

152 genes of which Tn mutants showed attenuated piglet infection were identified.

153 n, Tn mutants of 14 genes displayed enhanced piglet infection.

154 resulting in less mortality in a gnotobiotic piglet-infection model.

155 f Adh were also confirmed in both murine and piglets infectious models in vivo.

156 Compared with 100% protection in piglets initially inoculated with PC21A, 88% and 100% TC

157 The piglet is a reproducible model of acute or chronic CDI w

158 The piglet is a suitable model for determining the effective

159 rally delayed isohemagglutinin production in piglets is analogous to the developmental kinetics in hu

160 a coli (ETEC)-caused postweaning diarrhea in piglets is one such infection that may be prevented by o

161 The mean Stokes-Einstein viscosity of the piglet jejunal mucus was approx. two times lower than th

162 anti-A antibody production after "A-into-O" piglet kidney transplantation indicates that tolerance d

163 in three secondary lymphoid tissues between piglets lacking IPP and colonized controls, whereas both

164 diarrhea and high mortality rates in newborn piglets, leading to massive losses to the swine industry

165 f PEDV infection on the GM of sows and their piglets less than 10 days old.

166 In control piglets, <5% of microglia isolated from the hippocampus

167 sues and derived enteroids from MYO5B(P663L) piglets maintained CFTR on apical membranes, like tissue

168 fication than did late-term fetal piglets or piglets maintained germ-free.

169 We characterized a piglet model for Shigella dysenteriae type 1.

170 rately and in combination in the gnotobiotic piglet model of CDI.

171 We examined the piglet model of Clostridium difficile illness (CDI) in h

172 We used a piglet model of Cryptosporidium parvum infection to dete

173 (HRV) vaccine efficacy in a gnotobiotic (Gn) piglet model of HRV diarrhea.

174 ue AP deficiency and may prevent AKI in this piglet model of infant CPB/DHCA.

175 volved in sensing the necrotic bone, using a piglet model of Legg-Calve-Perthes disease.

176 ermia after transient hypoxia-ischaemia in a piglet model of perinatal asphyxia using clinically rele

177 ter transient cerebral hypoxia-ischemia in a piglet model of perinatal asphyxia using magnetic resona

178 nd PCCO analysis correlate with PATD CO in a piglet model of severe hemorrhagic shock.

179 The inbred piglet model represents a system that is comparable to h

180 In this study, we used a gnotobiotic piglet model to study determinants of pathogenicity of C

181 In a newborn piglet model we assessed the effect of E. coli lipopolys

182 Using a piglet model, the present study showed that inoculation

183 ner, SUCRAM, included in the diet of weaning piglets modulates the composition of lumenal-residing gu

184 tions to farm animal welfare issues, such as piglet mortality, are likely to lie within the scientifi

185 d piglets showed better penetrability of the piglet mucus.

186 Piglets (n = 263) were kept in litter groups or socialis

187 were collected from sows (n = 22) and their piglets (n = 33) beginning 1 week after the onset of the

188 Sham-operated piglets (n = 5) received no hypoxia-reoxygenation.

189 Eighteen newborn piglets (n = 6/group) with surfactant-deficient respirat

190 After 5-day adaption, piglets (n = 8/group) were orally administrated with eit

191 Three- to 5-day-old anesthetized piglets (n=51) underwent a single, rapid (117-266 rad/s)

192 In resting newborn piglets (n=6) on isoflurane anesthesia, we measured a me

193 Sham-operated piglets (n=8) underwent no asphyxia-reoxygenation.

194 Term newborn piglets (n=8/group) were anesthetized, intubated, instru

195 Thirty healthy Landrace/Large-White piglets of both sexes, aged 10 to 15 wks, whose average

196 which results in altered social behaviors of piglet offspring.

197 in the feces of 24 healthy and 12 diarrheic piglets on a high-density farm.

198 ter diversification than did late-term fetal piglets or piglets maintained germ-free.

199 males doubles mean litter size to about nine piglets per litter.

200 gement is expected to reduce stress, enhance piglet/pig welfare and production, and improve the econo

201 s in EcN-colonized compared with uncolonized piglets post-VirHRV challenge.

202 lphaEbeta7) expressing DCs in VAS versus VAD piglets postchallenge, indicating that VAD may interfere

203 tic cells (cDCs and pDCs) were higher in VAD piglets prechallenge, but decreased substantially postch

204 impaired mucociliary transport in newborn CF piglets prior to the onset of secondary manifestations.

205 Piglets randomly assigned to the SI group received SIs w

206 For 3 months, eight piglets received active EPIT, using Viaskin((R)) loaded

207 Blood group O piglets received kidney allografts from group A (AO-inco

208 e piglet feed-challenge experiment, only the piglets receiving feed containing the VHH-IgA-based anti

209 Piglets receiving the VHH-IgA-based antibodies in the fe

210 icantly higher weight gain compared with the piglets receiving VHH-IgG producing (dose 80 mg/d per pi

211 erent mammalian viruses were shed by healthy piglets, reflecting a high level of asymptomatic infecti

212 An additional 89 piglets remained isolated within their home pen (control

213 specific antibodies protected 100% and 0% of piglets, respectively, against oral challenge with a Stx

214 relative abundance for Meishan and Yorkshire piglets, respectively.

215 ation during normothermia and hypothermia in piglets resuscitated from arrest.

216 evels were induced in control VAD versus VAS piglet sera at postchallenge day 2.

217 ossess the IgG proteolytic activity and that piglet serum samples contain specific antibodies against

218 s evaluated by the weekly testing of sow and piglet serum samples on a SVA VP1 recombinant protein (r

219 ucus obtained from adult pigs vs. 2-week old piglets showed better penetrability of the piglet mucus.

220 Two out of 15 piglets showed clinical symptoms compatible with S. suis

221 In addition male piglets showed impaired thermoregulation compared to fem

222 d clinical disease, the icPEDV-mut4-infected piglets showed no clinical symptoms and exhibited normal

223 Sow fed piglets showed significantly more VE-Cadherin, which ass

224 Inoculation of three-week-old piglets showed that A2MC2-P90 is avirulent and elicits i

225 ere analysed by a pathologist unaware of the piglets' status.

226 infection was independently associated with piglet stuffing consumption (RR = 1.69 [1.04-2.73], P =

227 Ten piglets submitted to an experimental model of acute resp

228 Seven piglets submitted to experimental ventilator-induced lun

229 physiological and behavioural indicators of piglet survival differed between the sexes and whether l

230 In contrast, azithromycin-treated piglets survived the infection and had little or no brai

231 and ciliary body hemorrhages were common in piglets that experienced a single, rapid head rotation.

232 lower-respiratory tract were reduced only in piglets that had received intranasal alpha-GalCer.

233 ti-A/B antibodies were measured over time in piglets to establish developmental antibody kinetics.

234 Here, we describe the use of piglets to evaluate the efficacy and mechanism of action

235 of gastric eosinophilia in peanut-sensitized piglets to evaluate the efficacy of epicutaneous immunot

236 Experiments were conducted in piglets to evaluate the kinetics of BPA, BPS, and their

237 ously breathing surfactant-deficient newborn piglets to investigate the continuous positive airway pr

238 The tendency of socialised piglets to play fight with non-littermates did not affec

239 In a test of spatial learning, PRRSV piglets took longer to acquire the task, had a longer la

240 Contrary to the hypothesis, among piglets treated with anti-TcdA, those with A+B- infectio

241 Asphyxiated piglets treated with cyclosporine had lower plasma tropo

242 were investigated by dynamic PET studies in piglets under baseline and blocking conditions using the

243 Piglets underwent hypoxic-asphyxic cardiac arrest or sha

244 effects were also documented in gnotobiotic piglets using the same consortium and Malawian diet.

245 prevalence of pulmonary edema was 20% among piglets ventilated with low strain rates and 73% among t

246 Piglets ventilated with low strain rates had an inspirat

247 liquid manure sampled at the farm where the piglet was born and in the untreated island wastewater.

248 tory molecule IL-10 in comparison to sow-fed piglets was observed.

249 In a dynamic PET study in one piglet, we detected a higher uptake of [(18)F]6b in the

250 Thirty-three newborn piglets were acutely instrumented for continuous monitor

251 Thirty piglets were allocated at random to five groups: the lun

252 ous administration of the tracer in mice and piglets were assessed to determine the organ doses (ODs)

253 Crossbred piglets were assigned to three groups, intracranially in

254 Piglets were blindly, block randomized to receive IV bol

255 Piglets were block-randomized to receive intravenous bol

256 ghly virulent PEDV strain, all the surviving piglets were challenged with PC21A at 3 weeks postinocul

257 Gnotobiotic piglets were colonized with EcN, LGG, or EcN+LGG or unco

258 s of recovery from C. hominis infection, the piglets were completely protected against subsequent cha

259 Germ-free piglets were consistently and extensively colonized afte

260 Newborn piglets were divided into 3 groups (n = 5/group): normox

261 Piglets were exposed to a second 10-day period of PPE or

262 PRRSV piglets were febrile (p < 0.0001), anorectic (p < 0.0001

263 significantly influenced by diet, 2-day old piglets were fed soy or milk formula (n = 6/group/gender

264 ls were cooled to 18 degrees C with CPB, the piglets were in DHCA for 120 minutes, and the piglets we

265 To evaluate viral pathogenesis, piglets were infected with either icPEDV or icPEDV-mut4.

266 ng two novel animal models: a model in which piglets were inoculated orogastrically and a model in wh

267 Gnotobiotic piglets were orally challenged with C hominis oocysts, a

268 Thirty-six newborn piglets were randomized (all groups n = 9), with interve

269 68 piglets were randomized to cardiac arrest or sham proced

270 Piglets were randomized to receive an IV bolus of cyclos

271 global hypoxic-ischaemic insult, 17 newborn piglets were randomized to the following: (i) therapeuti

272 Following hypoxia-ischemia, 20 newborn piglets were randomized to: (i) Cooling 1-13 h (HT; n =

273 Piglets were randomly assigned to receive either 3:1 res

274 12 piglets were separated into 2 groups.

275 iglets were in DHCA for 120 minutes, and the piglets were then rewarmed on CPB to 38 degrees C and ma

276 Gnotobiotic piglets were used to investigate cross-protection.

277 teroidetes, the dominant bacteria in healthy piglets, were replaced by Firmicutes in asymptomatic and

278 reased in asymptomatic piglets and diarrheal piglets when compared to those of the healthy piglets.

279 example between birth weight and survival of piglets, where animals of extreme weights have lower sur

280 fed group in comparison to milk formula-fed piglets, whereas in milk formula-fed pigs Enterobacteria

281 ed lung injury piglets compared with control piglets, whereas regions suffering tidal recruitment or

282 Inoculation of 48-h-old conventional piglets with 10(11) CFU of the wild-type strain (NY-4) o

283 es from control piglets (WT and CFTR+/-) and piglets with CF-like disease (CFTR-/- and CFTR-/DeltaF50

284 Glands from piglets with CF-like disease responded qualitatively to

285 radiodense microdisks in airways of newborn piglets with CF.

286 uction, and airway size reduction in newborn piglets with cystic fibrosis before the onset of airway

287 On the day they were born, piglets with cystic fibrosis exhibited air trapping more

288 Moreover, newborn piglets with cystic fibrosis had increased airway resist

289 On the day they are born, piglets with cystic fibrosis lack airway infection and i

290 efore, we used newborn wild-type piglets and piglets with cystic fibrosis to assess air trapping, air

291 and improves functional recovery in newborn piglets with hypoxia-reoxygenation.

292 In newborn piglets with respiratory distress syndrome, the nebuliza

293 okine concentrations in the sera of mice and piglets with systemic and nonsystemic CDI and found that

294 y inoculated neonatal, conventional suckling piglets with TC-PC177 or PC21A to compare their pathogen

295 Infection of piglets with the parental Colorado strain, icPEDV-wt, or

296 culated five groups of 5-day-old gnotobiotic piglets with the three mutants, icPC22A, or a mock treat

297 Immunization of newly weaned piglets with UV-killed pandemic H1N1 A/California/04/200

298 use of the need to abolish the castration of piglets without anaesthesia/analgesia, the pig industry

299 Secretion rates from control piglets (WT and CFTR+/-) and piglets with CF-like diseas

300 Isolation of islets from neonate piglets yielded identical islet equivalent quantities to