ライフサイエンスコーパス: pinch

1 PAT-6 (alpha-parvin/actopaxin), and UNC-97 (PINCH).

2 ation of the hind paws (brush, pressure, and pinch).

3 and without physical provocation (mild tail pinch).

4 many proteins, including UNC-97 (vertebrate PINCH).

5 D) of ILK and the first LIM domain (LIM1) of PINCH.

6 angle, and skilled motions such as precision pinch.

7 titively inhibit the interaction of ILK with PINCH.

8 er and were characteristically distorted and pinched.

9 rom initiation of coat formation to membrane pinching.

10 egion for small enough values of the time to pinching.

11 by Tbeta(4) and the focal adhesion proteins PINCH-1 and ILK on NF-kappaB activity in this study open

12 fects of its intracellular binding partners, PINCH-1 and ILK, on NF-kappaB activity after TNF-alpha s

13 beta3 null mice, there were lower levels of PINCH-1 and ILK-1.

14 High expression of both PINCH-1 and myoferlin correlates with poor clinical outc

15 types of apoptosis-resistant cancer cells on PINCH-1 and provide new insights into the molecular mech

16 Such an interface suggests a transient Nck-2/PINCH-1 association process that may trigger rapid focal

17 Thus, PINCH-1 contributes to apoptosis resistance through supp

18 stigated the signaling pathway through which PINCH-1 contributes to apoptosis resistance.

19 Mechanistically, PINCH-1 controls myoferlin level through its interaction

20 Depletion of DRP1 reverses PINCH-1 deficiency-induced defects on mitochondrial dyna

21 Small interfering RNA-mediated knockdown of PINCH-1 disrupted the cytoskeleton and caused apoptosis

22 In a mouse model of obstructive nephropathy, PINCH-1 expression increased in a time-dependent manner,

23 PINCH-1 formed a ternary complex with ILK at the focal a

24 Ablation of PINCH-1 from breast cancer cells diminished myoferlin le

25 Finally, ablation of PINCH-1 from lung adenocarcinoma in mouse increases DRP1

26 These findings suggest that PINCH-1 functions as a molecular platform for coupling a

27 The functions and mechanism of PINCH-1 in cancer, however, remain to be determined.

28 Knockout (KO) of PINCH-1 increases dynamin-related protein 1 (DRP1) expre

29 th an ILK inhibitor or disruption of the ILK/PINCH-1 interaction by overexpressing a dominant-negativ

30 Here, we show that PINCH-1 interacts with myoferlin, a transmembrane protei

31 PINCH-1 is a cytoplasmic component of the cell-extracell

32 To determine whether PINCH-1 is also involved in the EMT process, we investig

33 PINCH-1 is an adaptor protein that binds to the integrin

34 Here we show that PINCH-1 is highly expressed in lung adenocarcinoma and p

35 Furthermore, overexpression of PYCR1 in PINCH-1 KO cells restores proline synthesis and cell pro

36 y 3 x 10(-3) M) between Nck-2 SH3 domain and PINCH-1 LIM4 domain.

37 The C-terminal tail not only regulates PINCH-1 localization to focal adhesions but also functio

38 Loss of PINCH-1 markedly increases the level of Bim and promotes

39 TGF-beta1 induced PINCH-1 mRNA and protein expression in human proximal tu

40 PINCH-1 promotes activating phosphorylation of Src famil

41 Overexpression of PINCH-1 suppressed epithelial markers E-cadherin and ZO-

42 Mechanistically, PINCH-1 suppresses Bim not only transcriptionally but al

43 n deposition, indicating that the ability of PINCH-1 to stimulate EMT is ILK-dependent.

44 extracellular assembly, whereas knockdown of PINCH-1 via small interfering RNA reduced TGF-beta1-medi

45 We report here that PINCH-1, a cytoplasmic component of cell-extracellular m

46 PINCH-1, a widely expressed protein consisting of five L

47 Vbeta3 integrin expression, stabilization of PINCH-1, and remodeling of the cytoskeleton.

48 Functionally, re-expression of PINCH-1, but not that of a myoferlin-binding defectiveDe

49 on of PINCH-1; Ox-LDL decreased the level of PINCH-1, but the application of mechanical stretch or ov

50 ults identify a signaling axis consisting of PINCH-1, DRP1 and PYCR1 that regulates mitochondrial dyn

51 t a ternary protein complex that consists of PINCH-1, integrin-linked kinase, and alpha-parvin, cytop

52 We conclude that PINCH-1, through its interaction with ILK, plays an impo

53 Overexpression of the PINCH-1-binding ankyrin repeat domain of ILK but not tha

54 kyrin repeat domain of ILK but not that of a PINCH-1-binding defective mutant form of the ankyrin dom

55 oferlin expression was sufficient to reverse PINCH-1-deficiency induced inhibition on breast cancer p

56 important evidence for a crucial role of the PINCH-1-ILK-alpha-parvin complex in the control of podoc

57 n the podocytes in which the assembly of the PINCH-1-ILK-alpha-parvin complex was compromised was det

58 Concomitantly, an increased amount of the PINCH-1-ILK-alpha-parvin complex was detected in the dif

59 n effectively inhibited the formation of the PINCH-1-ILK-alpha-parvin complex.

60 ression of glomerular failure, regulates the PINCH-1-integrin-linked kinase-alpha-parvin (PIP) comple

61 These results reveal a PINCH-1-myoferlin signaling axis that is critical for br

62 breast cancer progression induced by loss of PINCH-1.

63 over of Bim, is suppressed by the removal of PINCH-1.

64 C abolished the stretch protective effect on PINCH-1.

65 ely blocked apoptosis induced by the loss of PINCH-1.

66 -induced apoptosis involved stabilization of PINCH-1; Ox-LDL decreased the level of PINCH-1, but the

67 left hand were: grip strength: 10/13 kg; key pinch: 3/3 kg; Kapandji score: 6/9 of 10; Carroll score:

68 We show that by pinching a glass-i.e., by probing its response to force

69 ns in glass physics, can be obtained through pinching a glass.

70 ng the response pattern observed during tail-pinch, a representative stressful procedure.

71 d proteins), and the ability to activate ILK/PINCH/Akt, and other signaling molecules important in bo

72 a stable cytosolic complex and that the ILK.PINCH.alpha-parvin complex is recruited to integrin adhe

73 We conclude that the recruitment of the ILK.PINCH.alpha-parvin complex to membrane adhesion complexe

74 and a significant decrease in expression of PINCH and alpha-parvin, which, along with ILK, form a st

75 associations of radiographic variables with pinch and grip strength among individuals with radiograp

76 l skeletal muscle measurements, such as hand pinch and grip strength, show the strongest correlation

77 theta rhythmic activity was elicited by tail pinch and in which a slower theta rhythm persisted after

78 significantly facilitated dural and noxious pinch and innocuous brush evoked firing from the TCC.

79 to natural arousing stimuli (one-minute tail-pinch and one-minute social interaction with another mal

80 Hallmarks of memristive behavior include pinched and frequency-dependent I-V hysteresis loops and

81 uate two sample dispensing schemes, modified pinched and gated injections.

82 d aversion evoked by stimuli (including skin pinching and burn injury) that-in humans-produce sustain

83 final value of 30 nm just before coated-pit pinching and formation of the coated vesicle.

84 rticularly interesting Cys-His-rich protein (PINCH) and affects the host ILK-PINCH interaction in vit

85 first discovered as an interactor of UNC-97 (PINCH) and UNC-96, components of an M-line costamere in

86 unoprecipitation analysis indicted that ILK, PINCH, and alpha-parvin form a stable cytosolic complex

87 /threonine kinase, and its binding proteins, PINCH, and alpha-parvin may be recruited to membrane adh

88 esion (FA) complex components beta-integrin, PINCH, and integrin-linked kinase (ILK) caused formation

89 omplex between integrin-linked kinase (ILK), PINCH, and parvin is an essential signaling platform, se

90 sia was discontinued, rats recovered to tail pinch, and TBI was delivered by controlled cortical impa

91 ree surface as a function of the time to the pinching, and describe how surface viscous stresses grow

92 which AD and HIV may intersect and identify PINCH as a contributing factor to the accumulation of hy

93 reduction in withdrawal threshold to muscle pinch as adults (P < 0.05).

94 Decreased ILK and PINCH as well as alterations of components of related si

95 e, dominant negative version of the vesicle "pinch-ase" dynamin 2 (dyn2K44A) inhibited the downregula

96 The responses to pinch at control, 10 V, 20 V, 30 V, and recovery were 58

97 The responses to pinch at control, 10 V, 20 V, and 30 V, and recovery wer

98 mechanical stimulation (brush, pressure, and pinch) at their respective receptive fields while a step

99 mechanical stimulation (brush, pressure, and pinch) at their respective receptive fields, while a ste

100 the viral ORF119L directly binds to the host PINCH, attenuates the host PINCH-ILK interaction, and th

101 onserved in other LIM domains, disrupted the PINCH binding to ILK and abolished the PINCH targeting t

102 Our in vitro data confirmed that PINCH binds to hyperphosphorylated (hp) Tau and to E3 ub

103 The N-terminal LIM1 domain of PINCH binds to ILK and is required for the targeting of

104 Transcriptional profiling analysis of paired pinch biopsies from different regions of the intestine i

105 a propria DP macrophages, may be missed from pinch biopsy sampling, which may preclude detecting viru

106 s topology to that of a disk through a "neck-pinching" boundary singularity.

107 C fibres expressing MRGPRD was activated by pinching but not by stroking, consistent with previous p

108 d net MeHg production but decreased when the pinched cocci (persister) form became the major morphoty

109 t the solution NMR structure of the core ILK.PINCH complex (28 kDa, K(D) approximately 68 nm) involvi

110 and is required for the targeting of the ILK-PINCH complex to focal adhesion sites in fibroblasts dur

111 mponent of the integrin-linked kinase-parvin-pinch complex.

112 rd of diabetic rats, suggesting that ILK and PINCH contribute to stabilization of axonal and dendriti

113 aintained for timescales over which a steady pinch current can be sustained, even at levels which wou

114 Here, we examined the effects of a strong pinch delivered to the rat posterior paw on spontaneous

115 nylium cation, C8H9(+) (1), which supports a pinched diatropic ring current, the C(2v) transition sta

116 to rapid unstable mode growth and resultant pinch disassembly.

117 the neck scale becomes much slower than the pinching dynamics: The turbulence freezes.

118 is is reminiscent of the well-known "tubular pinch effect," which arises from inertial effects.

119 ri-middle meningeal artery dural and noxious pinch evoked firing of neurons in the TCC.

120 Single endoscopic pinch FFPE biopsies (n = 41) were sampled at both active

121 lent spherical diameter) via elasto-inertial pinched flow fractionation (eiPFF).

122 l lift forces, which we term elasto-inertial pinched flow fractionation (eiPFF).

123 Pinched flow fractionation (PFF) is a microfluidic techn

124 sidewall roughness cannot be separated using pinched flow fractionation.

125 o achieve detection of oligonucleotides in a pinched-flow fractionation (PFF) microseparator was deve

126 stimulus was applied by a bilateral hindpaw pinch for 5 s that increased mean arterial pressure (MAP

127 Dental students applied greater mean peak pinch force (35.7 +/- 3.8 N) compared to dentists (24.5

128 The application of pinch force by dentists was related to the required scal

129 tal scaling leads to the application of less pinch force to accomplish scaling.

130 g forces, whereas students applied excessive pinch force to the tools.

131 Thumb pinch force was measured by a pressure sensor, whereas t

132 We also evaluated his grip and pinch force.

133 disorders is forceful pinching; however, the pinch forces and instrument forces during scaling are un

134 Nonetheless, the applied peak pinch forces in both groups are high and may pose a risk

135 A key step for the PINCH function is its localization to FAs, which depends

136 mple, larger map area correlated with weaker pinch grip force (r=-0.42, P=0.01).

137 However, during action observation of the pinch-grip movement, the increase of corticospinal excit

138 different frequencies during an index-thumb pinch-grip observation task.

139 risk factor for these disorders is forceful pinching; however, the pinch forces and instrument force

140 guing nonzero cross point, resolved from the pinched hysteresis current-potential (i-V) curves in con

141 esponding voltage current plot may exhibit a pinched hysteresis loop which is the fingerprint of a me

142 ctric field or high frequency, whereas these pinched hysteresis loops also can become normal by risin

143 Their biophysical properties lead to pinched hysteretic current-voltage dependence as well a

144 binds to the host PINCH, attenuates the host PINCH-ILK interaction, and thus impairs ILK signaling.

145 .e., when discontinued with recovery to tail pinch immediately before injury).

146 actors (UNC-95, LIM-8, and LIM-9) for UNC-97/PINCH in Caenorhabditis elegans.

147 METHODS AND To define the role of PINCH in myocardium, we generated mice that were doubly

148 urrent study addressed potential role(s) for PINCH in neurodegenerative diseases.

149 und that afferent activity evoked by noxious pinch in these preparations was conveyed to central gang

150 the initial contact force during telerobotic pinch in three sensory conditions: vision only, vision +

151 All stents except Supera were pinched in flexed limb postures.

152 ulations in analogous to the classical theta-pinches in laboratory plasmas.

153 he ongoing activity and responses to noxious pinches in nociceptive VTT neurons were frequently inhib

154 d to produce the observed degree of membrane pinching in liposomes.

155 light the importance of studying the role of PINCHs in human cardiac injury and cardiomyopathy.

156 hese results demonstrate essential roles for PINCHs in myocardial growth, maturation, remodeling, and

157 ASK knock-out animals unresponsive to a tail pinch; in assays of sedation (loss of movement) and hypn

158 onic cells increase their firing during tail pinch-induced brain state-activation.

159 sensitivity of 500 fold compared to a normal pinched injection using fluorescence detection.

160 ein, respectively, relative to a traditional pinched injection.

161 ich protein (PINCH) and affects the host ILK-PINCH interaction in vitro in fathead minnow (FHM) cells

162 domain, revealing the molecular basis of ILK-PINCH interactions and providing a structural descriptio

163 .59+/-0.08*, 0.75+/-0.05*, 0.49+/-0.07*) and pinch (ipsilaterally: 0.89+/-0.08, 0.46+/-0.05*, 0.54+/-

164 s from HIVE, AD and FTD patients showed that PINCH is increased and binds to hp-Tau.

165 the situation in adult where high-intensity pinch is normally required.

166 Our previous studies also report that PINCH is recalled by neurons showing decreased levels of

167 ovel modular recognition and demonstrate how PINCH is specifically recruited by ILK to mediate the FA

168 sting new cysteine- histidine- rich protein (PINCH) is an adaptor protein that our data have shown is

169 h the animal cell uses a contractile ring to pinch itself in half.

170 rrelated with syncytium formation induced by PINCH knockdown.

171 x of the ILK ankyrin repeat domain (ARD) and PINCH LIM1 domain, respectively, are evaluated.

172 The PINCH LIM1-2 fragment also inhibited tension development

173 The PINCH LIM1-2 fragment inhibited the recruitment of endog

174 We expressed the GFP-PINCH LIM1-2 fragment, consisting only of LIM1-2 domains

175 grip the two contiguous zinc fingers of the PINCH LIM1.

176 from punctate dimples, to the formation of a pinched liposomal funnel that may impinge on the apparen

177 ance of accumulating hp-Tau, suggesting that PINCH may play a role in stabilizing hp-Tau.

178 t practice of evaluating maximal forces with pinch meters.

179 ctroosmotic flow carrying a hydrodynamically pinched, mixed sample, resulting in the separation of th

180 An 'iterative pinching' model is proposed wherein FtsZ itself generate

181 Additional twist and pinch motions were observed in an open ORC conformation

182 c particle separation technique that employs pinching of particles to a narrow microchannel.

183 This slow process resulted in a pinching of the inclusion, protrusion out of the cell wi

184 The larger cations cause a pinching of the S...S contact, which is responsible for

185 ound to be insufficient to provide mid-cell "pinching" of the parental cell to form two daughter cell

186 clathrin-coated pits (CCPs) that eventually pinch off and internalize as clathrin-coated vesicles.

187 thrin-coated pits assemble on a membrane and pinch off as coated vesicles.

188 ence of cytoplasmic chromatin fragments that pinch off from intact nuclei of primary cells during sen

189 Cyclonic eddies generally pinch off from meanders in the California Current, poten

190 of glucose, and the endocytic vesicles then pinch off from the plasma membrane.

191 n the accumulation of virions that failed to pinch off from the plasma membrane.

192 Subsequently, vesicles pinch off from the tips of the tubular structures in a p

193 rane, where it concentrates on vesicles that pinch off from this organelle.

194 ermal fluctuations can fuse the membrane and pinch off the vesicle.

195 thrin-coated pits (CCPs) that invaginate and pinch off to form clathrin-coated vesicles (CCVs).

196 of protrusions that elongate and eventually pinch off to form separate daughter cells.

197 considerably smaller than the virus during 'pinch off'.

198 The vacuole membrane seals and pinches off behind the parasite through an unknown mecha

199 face between an aqueous and an oil phase and pinching off droplets.

200 receptor complexes, evidently by inhibiting pinching off of endocytic vesicles containing the cluste

201 inates, to a top target plate before rapidly pinching off to deposit the sample on the target with pr

202 cle forms at the end of the tube, eventually pinching off to form a "free" vesicle.

203 anisms and undergo further maturation before pinching off to form clathrin-coated vesicles (CCVs).

204 ose their clathrin lattice within seconds of pinching off, through the action of the Hsc70 "uncoating

205 O-shaped, fully formed pits, captured while pinching off.

206 ncement mode of operation, achieving channel pinch-off and drain-source current saturation within the

207 ught that melt segregation is prevented by a pinch-off at melt fractions slightly below the percolati

208 milar regime restores universality to bubble pinch-off by erasing the system's memory of the initial

209 Here, we show that the pinch-off dynamics of a bubble confined in a capillary t

210 Here, we consider bubble pinch-off in a turbulent flow representative of natural

211 Although bubble pinch-off is an archetype of a dynamical system evolving

212 perse droplets because fluctuation-dominated pinch-off may allow the unique situation where satellite

213 Our results suggest that the pinch-off mechanism may be assisted by a pearling-like i

214 Surprisingly, however, the pinch-off of a bubble in a large tank of viscous liquid

215 The pinch-off of a bubble is an example of the formation of

216 see text], where [Formula: see text] is the pinch-off or singularity time and [Formula: see text], i

217 the cross-over from the classical two-fluid pinch-off scenario of a liquid thread to the fluctuation

218 hese two proposals could be important in the pinch-off stage, however, where additional actin polymer

219 l bubble shape and flow field, but after the pinch-off starts, the turbulent time at the neck scale b

220 ile frozen, the turbulence can influence the pinch-off through the initial conditions.

221 n-channel JFET characteristics with a small pinch-off voltage V(P) of -0.25 V, nearly ideal subthres

222 Wettability alteration and bubble-oil pinch-off were identified as contributing mechanisms to

223 alyses of reshaping, including sintering and pinch-off, and of compositional evolution in a vacuum en

224 e turbulence sets the initial conditions for pinch-off, namely the initial bubble shape and flow fiel

225 rmed by polymerizing actin filaments; and 3) pinch-off.

226 rings, suggesting that these structures were pinched-off endosomes.

227 the transition from a fully formed pit to a pinched-off vesicle.

228 ally blocked the effects elicited by the paw pinch on cortical excitability, whereas systemic adminis

229 ermined whether they would be grasped with a pinch or clench (Grasp condition), functionally used wit

230 (Grasp condition), functionally used with a pinch or clench (Prehensile Use condition), or functiona

231 ctivated by noxious stimuli, such as hindpaw pinches or electrical footshocks.

232 ect use may be either prehensile (clenching, pinching) or non-prehensile (e.g., palming, poking), in

233 The integrin-linked kinase (ILK)-PINCH-parvin (IPP) complex interacts with the cytoplasmi

234 Calpain activation also disrupted the ILK-PINCH-Parvin complex and altered platelet adhesion and s

235 description of a key interaction in the ILK-PINCH-parvin scaffolding complex.

236 rtain focal adhesion proteins including ILK, PINCH, paxillin, and cdc42, as well as regulating the ep

237 Expression of ILK, PINCH, PI3K, GSK-3beta, tau, MAP2, synaptophysin and dre

238 s, the SLIT2-ROBO system may represent a key pinch point to regulate PDAC spread.

239 binding module form a substrate recognition "pinch point" that we propose aids in alginate binding an

240 Silencing PINCH prior to induction of hp-Tau resulted in more effi

241 vestigate the electron beam effects on the X-pinch produced K-shell Aluminum plasma.

242 PINCH proteins are 5 LIM domain-only adaptor proteins th

243 A potential role for PINCH proteins in myocardium remains unknown.

244 ich may reflect a redundant role for these 2 PINCH proteins in myocardium.

245 ILK and PINCH proteins levels were significantly decreased and b

246 Two PINCH proteins, PINCH1 and PINCH2, have been described i

247 Following the paw pinch, pyramidal cells exhibited a significant decrease

248 ibe how surface viscous stresses grow in the pinching region as the free surface approaches its break

249 alance the driving capillary pressure in the pinching region for small enough values of the time to p

250 everity (r = -0.31, P < 0.05), and number of pinch/release cycles (r = -0.31, P < 0.05), and positive

251 strength (P < 0.01) and a reduced number of pinch/release cycles per second (P < 0.05).

252 maximum voluntary contraction and visuomotor pinch/release testing) and tactile discrimination capaci

253 tasks such as rapid acquisition of precision pinch remains unknown.

254 von Frey filaments and gastrocnemius muscle pinch, respectively.

255 oing firing rate and stimulus-evoked (brush, pinch, sciatic nerve) responses were markedly enhanced a

256 Markov modeling reveals a novel "pinched" SF configuration that stretch activation rapidl

257 metry of the calixarene, which maintains its pinched shape even when carrying an overall molecular ch

258 Pinched shape hysteresis loops appeared in low temperatu

259 the painful abdominal area (78%), a positive pinch sign (78%), a positive Carnett's sign (87%), and a

260 ied by trapping, leading to the formation of pinched spots of high density, curvature and pressure.

261 profiles in various tactile motions (shear, pinch, spread, torsion, and so on).

262 in the conduction pathway indicate that this pinched state impairs ion conduction.

263 reased responses to phasic brush, press, and pinch stimuli applied to identified peripheral receptive

264 trated reduced maximum voluntary contraction pinch strength (P < 0.01) and a reduced number of pinch/

265 ficantly negatively associated with grip and pinch strength (P < 0.05).

266 d relationships of the subscales to grip and pinch strength and a single-item pain measure.

267 ere used to examine associations of grip and pinch strength with 1) OA in joint groups (proximal inte

268 had the strongest correlation with grip and pinch strength, and the pain subscale had the strongest

269 We compared pinch strength, dynamic manipulation ability, and contra

270 severity is associated with reduced grip and pinch strength, even when controlling for self-reported

271 ated with both lower grip strength and lower pinch strength.

272 15 +/- 4% from baseline) in response to tail pinch stress paradigm.

273 d the PINCH binding to ILK and abolished the PINCH targeting to FAs.

274 nalyzed, and some preliminary experiments of pinch technologies are also conducted.

275 ve field center, and was usually greater for pinch than brush, although the selectivity for pinch ver

276 stimulus was applied by a 10-second hindpaw pinch that increased mean arterial pressure (MAP) and he

277 cal segments, P1 and P2, into proximity - a "pinch" that results in rate acceleration by almost three

278 ity peaks near the ends, which symmetrically pinch the fields.

279 resence of dicentrics, the cytokinetic septa pinch the nucleus, suggesting that dicentrics are severe

280 ontraction of the spicule-associated muscles pinch the vas deferens opening, thus blocking sperm rele

281 Z-ring contracts before septum formation and pinches the cell into two equal halves.

282 zed turbulence in the form of giant vortices pinches the eastward jet, forming polygonal shapes.

283 tracellular helix arrangement allosterically pinches the SF.

284 of the coagulum from the fistulous tracts by pinching the eyelid horizontally.

285 using mechanical stimulation like poking or pinching the insect, but such stimuli are hard to contro

286 sient whole-body tonic immobility induced by pinching the skin at the back of the neck ("scruffing").

287 The LIM-only adaptor PINCH (the particularly interesting cysteine- and histid

288 ibited the recruitment of endogenous ILK and PINCH to integrin adhesion sites and prevented their ass

289 h depends critically on the tight binding of PINCH to integrin-linked kinase (ILK).

290 ere located by applying brush, pressure, and pinch to the upper body.

291 se limitations through monolithic systems of pinch valves and suction pumps for purging of sweat as a

292 lses is generated by opening and closing two pinch valves interchangeably, so that either sample or s

293 tepper motor driven stage, solenoid-actuated pinch valves, miniaturized peristaltic pumps as well as

294 nch than brush, although the selectivity for pinch versus brush was not as great as with excitatory r

295 in current-evoked firing elicited by the paw pinch was inversely correlated with the baseline firing

296 Green fluorescent protein (GFP)-ILK and GFP-PINCH were expressed in tracheal muscle tissues and both

297 rsal horn neuronal responses to pressure and pinch were observed during SSC stimulation.

298 and both endogenous and recombinant ILK and PINCH were recruited to the membrane in response to ACh

299 enerated in our experiments form a flowing Z-pinch, which is generally unstable to the m = 1 kink ins

300 ss spectrometry predicted the interaction of PINCH with Tau and with members of the heat shock respon