ライフサイエンスコーパス: planar cell polarity

1 the apical membrane during the initiation of planar cell polarity.

2 protein (BMP) signaling, cell migration, and planar cell polarity.

3 ab23-regulated membrane traffic to cilia and planar cell polarity.

4 ecification, differentiation, downgrowth and planar cell polarity.

5 g pathway that regulates Hippo signaling and planar cell polarity.

6 suggest that Dchs1-Fat4 signaling influences planar cell polarity.

7 but not directly in MET channel function or planar cell polarity.

8 fluid flow and the developmental process of planar cell polarity.

9 ing network regulates both transcription and planar cell polarity.

10 lia are polarized coordinately and display a planar cell polarity.

11 nopus oocyte contains components of both the planar cell polarity and apical-basal polarity pathways,

12 d on the embryo have been used in studies on planar cell polarity and as models for the cytoskeletal

13 These include sonic hedgehog, wingless, planar cell polarity and fibroblast growth factor, which

14 mutant hair cells also displayed defects in planar cell polarity and morphogenesis of the stereocili

15 TK7 pseudo-kinase plays an essential role in planar cell polarity and the non-canonical Wnt pathway i

16 g signaling pathway, resulting in defects of planar cell polarity and tissue maintenance.

17 larize cells in the plane of the epithelium (planar cell polarity) and to affect growth via the Warts

18 on, alteration of intracellular calcium, and planar cell polarity are examined.

19 PRICKLE2 distribution reveals the planar cell polarity axis in the underlying epithelium i

20 Other epithelia need Rho-kinase for planar cell polarity but it is not known whether Rho-kin

21 cal cadherin Fat is a conserved regulator of planar cell polarity, but the mechanisms by which Fat co

22 a signaling pathway that controls growth and planar cell polarity by regulating the membrane localiza

23 nd that 5-HT and mdDA axons express the core planar cell polarity components Frizzled3, Celsr3, and V

24 In the nephron, planar cell polarity controls elongation along the proxi

25 , interactions and functions of the maternal planar cell polarity core protein Vangl2 and the apical-

26 red shape of hair cells with innervation and planar cell polarity defects.

27 Initially, planar cell polarity determines the orientation of LEC m

28 ed by regulation of cell differentiation and planar cell polarity during development.

29 the CNV showed discrete contributions of the planar cell polarity effector SCRIB and the splicing fac

30 ophila and for its conserved function during planar cell polarity establishment.

31 Vangl2, a core component in planar cell polarity, forms Wnt-induced receptor complex

32 Frizzled/planar cell polarity (Fz/PCP) signaling controls the ori

33 be in detail two of these: a mutation in the planar cell polarity gene scribbled homolog (Drosophila)

34 Mutations in the core planar cell polarity gene Van Gogh-like 2 (Vangl2) resul

35 When combined with a mutant allele of the planar cell polarity gene Vangl2 (Vangl2(Lp)), Fz1 and/o

36 roles for planar polarity and for the novel planar cell polarity gene, Ptk7, as essential regulators

37 These findings show that planar cell polarity genes are required for responses to

38 the cue, and reoriented mitosis required the planar cell polarity genes dachsous, fat, and atrophin.

39 ctorin-based matrix, epithelial cilia or the planar cell polarity genes Vangl2 and Ptk7 In wild-type

40 for pineapple eye, likewise dependent on the planar cell polarity genes.

41 at regulate folate one-carbon metabolism and planar cell polarity have been strongly implicated.

42 Fat-Dachsous signaling systems locally align planar cell polarities in Drosophila epithelia.

43 The frizzled/starry night pathway regulates planar cell polarity in a wide variety of tissues in man

44 he conserved frizzled (fz) pathway regulates planar cell polarity in both vertebrate and invertebrate

45 gnaling/signal transduction pathway controls planar cell polarity in both vertebrates and invertebrat

46 n dynamics that establish columnar shape and planar cell polarity in epidermal progenitors.

47 echanism also contribute to the formation of planar cell polarity in mechanosensory epithelia.

48 tein that regulates microtubule dynamics and planar cell polarity in multi-ciliated cells.

49 cle orientation depends on genes that define planar cell polarity in the epidermis.

50 rganisms, been shown to be associated with a planar cell polarity in the organisation of the actin-my

51 ommatidial rotation, functional readouts of planar cell polarity in the wing and eye respectively, a

52 play a conserved role in cilia formation and planar cell polarity in zebrafish.

53 g and genetic analysis of proteins linked to planar cell polarity (Inturned, Fuzzy and Wdpcp), we ide

54 These results suggest that ependymal planar cell polarity is a multistep process initially or

55 gh their hair bundles develop normally their planar cell polarity is compromised.

56 Once the planar cell polarity is established, microtubules are no

57 Planar cell polarity is normal in the vestibular epithel

58 as grossly normal in the cochlea, indicating planar cell polarity is not markedly affected.

59 Moreover, the planar-cell-polarity member, Prickle-1, is recruited spe

60 on CE is robust to relatively high levels of planar cell polarity misalignment and to the presence of

61 ements of cell polarity suggest that classic planar cell polarity molecules are not directly influenc

62 cts at least partially independently of core planar cell polarity molecules at the plasma membrane, a

63 ling during kidney morphogenesis affects the planar cell polarity of the epithelium and leads to tubu

64 xpansion of satellite stem cells through the planar cell polarity pathway and by activating the Akt/m

65 The planar cell polarity pathway and hydrodynamic forces hav

66 g in a novel pathway, independently from the planar cell polarity pathway and in parallel to lin-17/f

67 eover, we demonstrate that components of the planar cell polarity pathway colocalize to recycling end

68 Here we show that the Dchs1-Fat4 planar cell polarity pathway controls cell orientation i

69 ry sensory organ, the Usher complex, and the planar cell polarity pathway in the formation and polari

70 Although the traditional planar cell polarity pathway is not involved, we obtaine

71 ng satellite stem cell expansion through the planar cell polarity pathway, as well as myofiber hypert

72 Vangl2, a core component of the Planar Cell Polarity pathway, is necessary for the cauda

73 molecular control via the non-canonical Wnt/planar cell polarity pathway, Shh/BMP signalling, and th

74 f-renewal divisions via the noncanonical WNT/planar cell polarity pathway, to modify stem cell pool e

75 lamingo/CELSR, an essential component of the planar cell polarity pathway.

76 enter through a mechanism reminiscent of the planar cell polarity pathway.

77 tion between genes of the non-canonical Wnt (planar cell polarity) pathway and NTDs provides candidat

78 nraveling novel and unexpected functions for planar cell polarity pathways in HSC fate.

79 et genes not by signalingviathe WNT/Ca(2+)or planar cell polarity pathways, but rather by inhibiting

80 nts of the highly conserved apical-basal and planar cell polarity pathways, suggesting a possible reg

81 vertebrate neural tube formation, connecting planar cell polarity patterning to contraction of specif

82 hs1 signalling has been proposed to regulate planar cell polarity (PCP) and activity of the Hippo eff

83 f cells form as a result of coupling between planar cell polarity (PCP) and anisotropic tissue-scale

84 y cadherins are giant proteins that regulate planar cell polarity (PCP) and cell adhesion in bilateri

85 r and slope of morphogen gradients influence planar cell polarity (PCP) and growth.

86 Planar cell polarity (PCP) and neural tube defects (NTDs

87 The Fat pathway controls both planar cell polarity (PCP) and organ growth.

88 ila protocadherin Fat (Ft) regulates growth, planar cell polarity (PCP) and proximodistal patterning.

89 The generation of planar cell polarity (PCP) and tissue shape during morph

90 The PCP effector gene Inturned regulates planar cell polarity (PCP) and wing hair formation in Dr

91 e demonstrate that several components of the planar cell polarity (PCP) arm of non-canonical Wnt sign

92 Defects in planar cell polarity (PCP) can disrupt spindle positioni

93 ssues appeared normal in mice lacking a core planar cell polarity (PCP) component, Vangl2.

94 The absence of planar cell polarity (PCP) core proteins Prickle1 and Pr

95 Planar cell polarity (PCP) describes the polarization of

96 Using this platform, we show that the planar cell polarity (PCP) effector Fuz was required for

97 and Fuzzy, proteins previously implicated as planar cell polarity (PCP) effectors and in developmenta

98 Planar cell polarity (PCP) establishes polarity within a

99 he two mouse homologues of a Drosophila core planar cell polarity (PCP) gene Van Gogh (Vang), we reve

100 we find that mouse embryos defective for the planar cell polarity (PCP) gene, Vangl2, exhibit increas

101 The pathway is a hierarchy with the Planar Cell Polarity (PCP) genes (aka the core genes) fu

102 Here we show that mutations in the planar cell polarity (PCP) genes Celsr1 and Vangl2 lead

103 Here we report that the planar cell polarity (PCP) genes Celsr3 and Fzd3 are req

104 ertebrate homologues of core tissue polarity/planar cell polarity (PCP) genes in Drosophila.

105 iptional activation of atypical cadherin and planar cell polarity (PCP) genes.

106 The Wnt/Planar cell polarity (PCP) has been associated with cili

107 Establishment of planar cell polarity (PCP) in a tissue requires coordina

108 (Fzr/Cdh1) in epithelial cell patterning and planar cell polarity (PCP) in Drosophila.

109 Planar cell polarity (PCP) in epithelia, orthogonal to t

110 nd Dachsous (Ds) have been found to underlie planar cell polarity (PCP) in many tissues.

111 led/starry night (fz/stan) pathway regulates planar cell polarity (PCP) in vertebrates and invertebra

112 Planar cell polarity (PCP) is a common feature of many e

113 Planar cell polarity (PCP) is a property of epithelial t

114 Planar cell polarity (PCP) is a ubiquitous property of a

115 Planar cell polarity (PCP) is an important conserved pro

116 In dividing cells of the mammalian skin, planar cell polarity (PCP) is maintained through the bul

117 A key step in generating planar cell polarity (PCP) is the formation of restricte

118 fish morphants are similar to those found in planar cell polarity (PCP) mutants, a pathway suggested

119 ensory organ to exhibit a particular form of planar cell polarity (PCP) necessary for mechanotransduc

120 function is the rotational and translational planar cell polarity (PCP) of E1 cells.

121 Planar cell polarity (PCP) organizes the orientation of

122 In the mammalian cochlea, the planar cell polarity (PCP) pathway aligns hair cell orie

123 Components of the planar cell polarity (PCP) pathway are required for the

124 Here, we provide evidence implicating the planar cell polarity (PCP) pathway as the downstream com

125 ferative divisions, and the re-expression of planar cell polarity (PCP) pathway components.

126 The vertebrate planar cell polarity (PCP) pathway consists of conserved

127 I found that components of the Wnt/Planar Cell Polarity (PCP) pathway control MB axon branc

128 The noncanonical Wnt/planar cell polarity (PCP) pathway controls a variety of

129 The planar cell polarity (PCP) pathway controls multiple cel

130 ong et al. add to mounting evidence that the planar cell polarity (PCP) pathway coordinates posterior

131 n by regulating the evolutionarily conserved planar cell polarity (PCP) pathway during embryonic morp

132 including beta-catenin and non-canonical Wnt/planar cell polarity (PCP) pathway factors, such as Daam

133 The planar cell polarity (PCP) pathway is a conserved non-ca

134 The planar cell polarity (PCP) pathway is a conserved pathwa

135 The planar cell polarity (PCP) pathway is best known for its

136 Recent studies established that the planar cell polarity (PCP) pathway is critical for vario

137 The planar cell polarity (PCP) pathway is necessary for the

138 We found that the planar cell polarity (PCP) pathway is required in alveol

139 The Wnt-planar cell polarity (PCP) pathway is the primary regula

140 The planar cell polarity (PCP) pathway organizes the cytoske

141 The evolutionarily conserved planar cell polarity (PCP) pathway regulates CE, and Wnt

142 The Wnt/planar cell polarity (PCP) pathway regulates directed ce

143 importance in development and physiology the planar cell polarity (PCP) pathway remains one of the mo

144 The vertebrate planar cell polarity (PCP) pathway shares molecular comp

145 gration is directed by the non-canonical Wnt planar cell polarity (PCP) pathway via Rho/ROCK.

146 Additionally, glypicans function in the planar cell polarity (PCP) pathway, and several PCP gene

147 at Celsr3 and Vangl2, core components of the planar cell polarity (PCP) pathway, are localized at dev

148 Loss of Wnt5, a putative ligand of the planar cell polarity (PCP) pathway, causes the SpM-SHF t

149 Several components of the Wnt/planar cell polarity (PCP) pathway, including the transm

150 The planar cell polarity (PCP) pathway, incorporating non-ca

151 of Vangl2, a transmembrane component of the planar cell polarity (PCP) pathway, rescued recessive Da

152 The Wnt planar cell polarity (PCP) pathway, through the recruitm

153 d PAH pericytes for abnormalities in the Wnt/planar cell polarity (PCP) pathway, which has been shown

154 Some of these processes signal via the planar cell polarity (PCP) pathway, which is a beta-cate

155 ochord taper involves three main mechanisms: Planar Cell Polarity (PCP) pathway-independent sibling c

156 t is required for explant elongation via the planar cell polarity (PCP) pathway.

157 n and seems to require signaling through the planar cell polarity (PCP) pathway.

158 of the primary body axis and depends on the planar cell polarity (PCP) pathway.

159 lypican 4, an essential component of the Wnt/planar cell polarity (PCP) pathway.

160 regulator of both the canonical Wnt and the planar cell polarity (PCP) pathway.

161 eta-catenin pathway and the noncanonical Wnt/planar cell polarity (PCP) pathway.

162 PTK7 is an essential component of the Wnt/planar cell polarity (PCP) pathway.

163 ommon planar axis specified by the conserved planar cell polarity (PCP) pathway.

164 Noncanonical Wnt/planar cell polarity (PCP) pathways contribute to proces

165 adherin Fat is a receptor for both Hippo and planar cell polarity (PCP) pathways.

166 Planar cell polarity (PCP) plays crucial roles in develo

167 thway, including Wnt5b and the transmembrane planar cell polarity (PCP) protein Vangl2.

168 cted by a nonautonomous function of the core planar cell polarity (PCP) protein VANGL2.

169 Planar cell polarity (PCP) proteins are distributed norm

170 ermis whereupon cell division, transmembrane planar cell polarity (PCP) proteins are removed from the

171 Core planar cell polarity (PCP) proteins are well known to re

172 We report here that planar cell polarity (PCP) proteins control convergent e

173 The core planar cell polarity (PCP) proteins coordinate the orien

174 Asymmetric localization of planar cell polarity (PCP) proteins is essential for tis

175 Planar cell polarity (PCP) proteins localize asymmetrica

176 increased levels of transcripts encoding the planar cell polarity (PCP) proteins SCRIB and VANGL1 cor

177 nization and require the concerted action of planar cell polarity (PCP) proteins that regulate cell e

178 nregulation on a number of cell polarity and planar cell polarity (PCP) proteins, and studies have sh

179 ir cell bundle alignment is mediated by core planar cell polarity (PCP) proteins, such as Vangl2, tha

180 symmetric subcellular localization of 'core' planar cell polarity (PCP) proteins, we find that altern

181 Whether planar cell polarity (PCP) proteins, which regulate cyto

182 Planar cell polarity (PCP) refers to coordinated polariz

183 Planar cell polarity (PCP) refers to the collective alig

184 Planar cell polarity (PCP) refers to the coordinated ali

185 Planar cell polarity (PCP) reflects cellular orientation

186 Planar cell polarity (PCP) regulates basal body (BB) doc

187 Planar cell polarity (PCP) regulates cell alignment requ

188 orientation are manifestations of epithelial planar cell polarity (PCP) required for proper perceptio

189 Planar cell polarity (PCP) requires the asymmetric sorti

190 certed action of tissue-level, intercellular planar cell polarity (PCP) signaling and a hair cell-int

191 Commissural axons engage planar cell polarity (PCP) signaling components to turn

192 Core planar cell polarity (PCP) signaling controls OCD and CE

193 Planar cell polarity (PCP) signaling controls the polari

194 Planar cell polarity (PCP) signaling controls tissue mor

195 Wnt-Frizzled/planar cell polarity (PCP) signaling establishes cell or

196 ed deafness therapies.SIGNIFICANCE STATEMENT Planar cell polarity (PCP) signaling has emerged as a co

197 et of signaling pathways and the role of Wnt/Planar cell polarity (PCP) signaling in adult neurogenes

198 These experiments implicate planar cell polarity (PCP) signaling in motor axon growt

199 Moreover, we find that blocking planar cell polarity (PCP) signaling in somitic muscle c

200 work has implicated Frizzled6 (Fz6)-mediated planar cell polarity (PCP) signaling in the initial spec

201 A role for planar cell polarity (PCP) signaling in the orientation

202 Wnt-Frizzled/Planar cell polarity (PCP) signaling is a conserved mech

203 Planar cell polarity (PCP) signaling is a key regulator

204 Planar cell polarity (PCP) signaling is essential for me

205 Planar cell polarity (PCP) signaling is essential in det

206 This regulatory link between Shh and planar cell polarity (PCP) signaling may also occur in o

207 Much of the Hippo and planar cell polarity (PCP) signaling mediated by the Dro

208 Frizzled (Fz)/planar cell polarity (PCP) signaling orchestrates cytosk

209 Here we provide evidence that planar cell polarity (PCP) signaling orchestrates direct

210 During vertebrate gastrulation, Wnt/planar cell polarity (PCP) signaling orchestrates polari

211 Planar cell polarity (PCP) signaling orients development

212 The planar cell polarity (PCP) signaling pathway governs col

213 The planar cell polarity (PCP) signaling pathway is crucial

214 Subcellular asymmetry directed by the planar cell polarity (PCP) signaling pathway orients num

215 wingless (Wnt)-beta-catenin (betaC) and Wnt-planar cell polarity (PCP) signaling pathways to facilit

216 Non-canonical Wnt/planar cell polarity (PCP) signaling plays a primary rol

217 ssential for patterning of the AP axis while planar cell polarity (PCP) signaling polarizes cells wit

218 o worms, whether and how this is mediated by planar cell polarity (PCP) signaling remain elusive.

219 We show that planar cell polarity (PCP) signaling specifies direction

220 An evolutionarily conserved planar cell polarity (PCP) signaling system employs intr

221 polarity is controlled by non-canonical Wnt/planar cell polarity (PCP) signaling, the hair cell-intr

222 g a candidate approach for genes involved in planar cell polarity (PCP) signaling, we identified Dros

223 cal beta-catenin signaling and Frizzled (Fz)-planar cell polarity (PCP) signaling.

224 sion (CE) defects, arising from impaired Wnt/planar cell polarity (PCP) signaling.

225 ther non-canonical pathways, WNT5A activates planar cell polarity (PCP) signaling.

226 The role of planar cell polarity (PCP) signalling in neural crest (N

227 Planar cell polarity (PCP) signalling is a well-conserve

228 Wnt planar cell polarity (PCP) signalling is critical in ver

229 to results from transgenic embryos in which Planar Cell Polarity (PCP) signalling is disrupted.

230 show that Scribble, a protein implicated in planar cell polarity (PCP) signalling, is necessary for

231 ateral polarization was under the control of planar cell polarity (PCP) signalling, was necessary for

232 Here, we show that in response to planar cell polarity (PCP) signals, Ral modulates asymme

233 n the ASP was dependent on components of the planar cell polarity (PCP) system in the disc, and neith

234 nd physiology of tissues and organs requires planar cell polarity (PCP) systems that orient and coord

235 PTK7 regulates epithelial morphogenesis and planar cell polarity (PCP) through modulation of actomyo

236 mb), originally identified as an effector of planar cell polarity (PCP) under control of Rho kinase,

237 n of this flow requires the establishment of planar cell polarity (PCP) whereby MCCs align hundreds o

238 ntation within the plane of a tissue, termed planar cell polarity (PCP), appear to be crucial for the

239 Many epithelia have a common planar cell polarity (PCP), as exemplified by the consis

240 lls within the plane of the tissue, known as planar cell polarity (PCP), is a recurring theme in biol

241 n of cells across the tissue plane, known as planar cell polarity (PCP), is manifested by the segrega

242 d identified genes required for PR survival, planar cell polarity (PCP), patterning and differentiati

243 Planar cell polarity (PCP), the coordinated and consiste

244 Planar cell polarity (PCP), the long-range in-plane pola

245 ften coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the e

246 The Ciona notochord displays planar cell polarity (PCP), with anterior localization o

247 mmon pathway suggestive of activation of wnt-planar cell polarity (PCP)-c-Jun N-terminal kinase (JNK)

248 Rosette dynamics are regulated by both planar cell polarity (PCP)-dependent and -independent pa

249 dermal cells become packed as they engage in planar cell polarity (PCP)-dependent movement.

250 are observed in ommatidial rotation (OR), a planar cell polarity (PCP)-mediated cell motility proces

251 ia have been implicated in the generation of planar cell polarity (PCP).

252 reociliary bundles, indicative of defects in planar cell polarity (PCP).

253 nt Drosophila protocadherin Fat (Ft) affects planar cell polarity (PCP).

254 ized, with a pattern suggestive of defective planar cell polarity (PCP).

255 have only recently been linked to a role in planar cell polarity (PCP).

256 originally in flies to coordinate epithelial planar cell polarity (PCP).

257 The planar cell polarity (PCP; non-canonical Wnt) pathway is

258 ts of canonical and noncanonical (Ca(2+) and planar cell polarity [PCP]) Wnt pathways, including IWP-

259 restingly, dyl mutants also display a unique planar cell polarity phenotype that is distinct from tha

260 PTK7, a tyrosine kinase receptor involved in planar cell polarity, plays a role in epithelial Wnt sig

261 tunes dishevelled levels, thereby modulating planar cell polarity processes.

262 ear late gastrulation accompanied by a VANGL planar cell polarity protein 2 (Vangl2)-regulated increa

263 nder flow and exhibit high expression of the planar cell polarity protein VANGL2.

264 The VANGL family of planar cell polarity proteins is implicated in breast ca

265 The latter - planar cell polarity - requires long-range regulation of

266 After NCC delamination, planar cell polarity signaling acts via RhoGTPases to co

267 this ciliopathy that (i) implicate ALMS1 in planar cell polarity signaling and (ii) suggest that the

268 The only known ligands for planar cell polarity signaling are Wnt proteins.

269 First, PAPC attenuates planar cell polarity signaling at the ectoderm-mesoderm

270 LIN-17 phosphorylation and is antagonized by planar cell polarity signaling components Van Gogh (VANG

271 ata suggest an important role for Ryk in Wnt/planar cell polarity signaling during vertebrate develop

272 Perturbation analyses demonstrate that planar cell polarity signaling enables cells to pivot in

273 Fat2/Lar signaling is similar to planar cell polarity signaling in terms of sub-cellular

274 Here we reveal a novel requirement for Wnt/planar cell polarity signaling in the anterior-posterior

275 Overall, our data suggest that Wnt/planar cell polarity signaling may be a global anterior-

276 Wnt-11/planar cell polarity signaling polarizes mesodermal cell

277 In this study we demonstrate that planar cell polarity signaling regulates morphogenesis i

278 e reporters, that WNT11 strongly induced JNK/planar cell polarity signaling while repressing the beta

279 Celsr1, a likely indicator of competence for planar cell polarity signaling.

280 etween Frizzled3 and Vangl2 is essential for planar cell polarity signaling.

281 ryos mutant for two proteins associated with planar cell polarity signaling: Vangl2 and Ptk7.

282 Wnt/PCP (planar cell polarity) signaling, one of the noncanonical

283 erating biliary epithelial cells express Wnt-Planar Cell Polarity signalling components following bil

284 Wnt/beta-catenin signalling and disrupts Wnt/planar cell polarity signalling in vivo.

285 ase 1 gene (ROCK1) is a key component of the planar cell polarity signalling pathway, which plays an

286 specification, and acts in parallel with the planar-cell-polarity system to determine the orientation

287 ost entirely by Dachsous and Fat, one of two planar cell polarity systems.

288 of research there are still basic aspects of planar cell polarity that are not well understood.

289 Oriented cell division is a feature of planar cell polarity that describes the orientation of t

290 he non-canonical Wnt-dependent regulation of planar cell polarity through the Formin homology protein

291 is an evolutionarily conserved regulator of planar cell polarity, tissue size and cell adhesion.

292 We demonstrate spindle alignments and planar cell polarities, which form a novel functional un

293 dent on Rho kinase, JNK and, to some extent, planar cell polarity within the epidermis.

294 onent of both the canonical and noncanonical/planar cell polarity Wnt pathways, modulates cell polari

295 The data suggest that JNK/planar cell polarity WNT signaling operates in the face

296 The non-canonical Wnt/planar cell polarity (Wnt/PCP) pathway plays a crucial r

297 The non-canonical WNT/planar cell polarity (WNT/PCP) pathway plays important r

298 the Wnt/calcium (Wnt/Ca) pathway and the Wnt/planar cell polarity (Wnt/PCP) pathway, in certain cellu

299 Wnt planar cell polarity (Wnt/PCP) signaling polarizes the m

300 orphogenesis (in particular the emergence of planar cell polarity), wound healing, and disease-progre