ライフサイエンスコーパス: planarity

1 a angles deviating by nearly 20 degrees from planarity.

2 ngly, Phe228 is significantly distorted from planarity.

3 distance of the peptide bond or the peptide planarity.

4 ivative 3 are predicted to be distorted from planarity.

5 s amino acid to alanine leads to chromophore planarity.

6 fferent types and degrees of distortion from planarity.

7 pyridazine rigidifies the ligands, restoring planarity.

8 ometric deviation of the diborepin core from planarity.

9 formations that are extremely distorted from planarity.

10 he geometry of the complex considerably from planarity.

11 paired with luciferases capable of enforcing planarity.

12 function to maintain the heme distorted from planarity.

13 ridgehead substituents and bridging rings on planarity.

14 that the system deviates significantly from planarity.

15 ch as the deformation of aromatic rings from planarity.

16 OX heme cofactor is extremely distorted from planarity.

17 C(2v) structure with a large distortion from planarity.

18 hosphatidylcholine bilayer surfaces approach planarity.

19 correlation between E(1/2)(ox) and degree of planarity.

20 d/or by disruption of the bridging base-pair planarity.

21 d reduce deformation of the chromophore from planarity.

22 me (d(z)(2)) orbital enhanced by iron out-of-planarity.

23 dge and there is substantial distortion from planarity.

24 peptide bonds systematically deviating from planarity--a net deviation of 53 degrees across five res

25 nsion of Zr-MOFs by finely-tuning the ligand planarity, advancing the structure diversification of me

26 inducing conformational control and enhanced planarity along a polymer or small molecule backbone at

27 emical characteristics but distinct backbone planarities and molecular orientations were successfully

28 sm in molecular catalysts conjoins molecular planarity and catalytic activation through competing fie

29 ortions of the Fe(2)S(2) inorganic core from planarity and displacements of the polypeptide chain.

30 The planarity and electron-deficient rigid structures enable

31 k is generated, removing the distortion from planarity and enhancing the influence of the substituent

32 harge carrier mobility by improving backbone planarity and facilitating short contacts between polyme

33 ffords polymers with high degree of backbone planarity and film ordering.

34 3D reconstructions reveal a high degree of planarity and homogeneity in solution for polygonal obje

35 ng its anticancer activity through increased planarity and introduction of functional groups.

36 S1P1 agonists are described extending beyond planarity and lipophilicity, and the impact and consider

37 offer increased stability, yet their typical planarity and pai-conjugated structures impedes ICT.

38 s 18a and 18b were canted significantly from planarity and projected the imidazoline substituents R(1

39 surface area, residue interface propensity, planarity and protrusion (SHARP2).

40 ions to endogenous FFAs, focused on breaking planarity and reducing lipophilicity, led to the identif

41 and explain its important role in enhancing planarity and rigidity of the molecules for enhancing th

42 henanthrene, which have different degrees of planarity and rigidity.

43 ular structures significantly distorted from planarity and S = 3/2 ground states.

44 d several other compounds indicated that the planarity and size of a molecule are important in its in

45 chain orientation enables increased backbone planarity and steric accessibility, and finally a planar

46 ed, which could be attributed to the similar planarity and sugar conformations for these two derivati

47 groups can vary by more than 25 degrees from planarity and that the true extent of nonplanarity is un

48 arities are structural features such as ring planarity and the absence of bond length alternation, sp

49 f the coumarin moiety can reduce the overall planarity and thus resonance of the coumarin nucleus, re

50 fects on doping efficiency, polymer backbone planarity, and Coulomb potential landscape.

51 Conjugation effectiveness, electron density, planarity, and geometry of charge-transfer pathways were

52 , the fluorene moieties maintained their own planarity, and one of the fluorene moieties was not invo

53 Peptide bonds strongly deviating from planarity are considered very rare features of protein s

54 nonplanar, deviating by over 20 degrees from planarity, are not strongly associated with active sites

55 d pi-extension and substantial twisting from planarity, are reported: specifically, two-ring 2TTMC, d

56 lation results in a dramatic increase of non-planarity around the amide N-C(O) bond.

57 aggregated form of TPE-mercury ions recovers planarity because of restricted rotational freedom promo

58 ations indicate that, despite differences in planarity between the molecules, the photophysical prope

59 ing the C-F bond of the radical anion out of planarity but also by increasing the exothermicity of th

60 gineered media not only maintain the surface planarity but also the homogeneity of the magnetic mater

61 the heme macrocycle by cyt b 5 but away from planarity by CPR.

62 the binding events, such as charge state and planarity, by lasso (least absolute shrinkage and select

63 are highly twisted, and this distortion from planarity can dramatically affect the stability and reac

64 7% of the gold-standard sample range for non-planarity, cochlear size and duct length.

65 polyacetylene core while retaining backbone planarity, conferring both ambient stability (LUMO = -4.

66 s computational prediction, we show that the planarity, conjugation, orientation of the dipole moment

67 esence of false-positives due to the maximal planarity constraint, and the inadequacy of the clusteri

68 quid phase, where structure, width, and edge planarity could be controlled chemically at the atomic l

69 wists the cannabinol biaryl framework out of planarity creating an axis of chirality.

70 ents that remove the constraints of membrane planarity, crowdedness, and support rigidity.

71 n the hydrazone moiety, identified by a high planarity degree at the pyrrolidine N(sp(3)) atom, that

72 but that the large majority of variation in planarity depends on tertiary effects.

73 esting decreased energy gaps with larger non-planarity, different from the neutral species.

74 active site of the E24Q enzyme deviates from planarity due to a 30 degrees twist of the carboxylate p

75 Deviation of the pai-system from planarity due to changes in the fluorophore ionization s

76 ation of the P(B) chlorophyll structure from planarity due to the axial ligand.

77 of the individual strands close to the quasi-planarity expected for a beta-sheet.

78 res that deviate considerably from the quasi-planarity expected for beta-sheets.

79 rkable affinity of the hypervalent region to planarity for all reaction mechanisms.

80 erestingly, however, the effect of molecular planarity has greater impact on PCB sorption to the nano

81 It was found that enhanced planarity, high crystallinity, and a delicate balance in

82 th the triangles retaining almost perfect co-planarity in even the most strained systems.

83 while the chromophore is largely confined to planarity in GFP.

84 shows that a higher propensity for backbone planarity in PBDT[2F]T leads to more pronounced, yet sta

85 est activity, pointing out the importance of planarity in the A,B-ring junction near C-5.

86 We found that compound 5, devoid of the planarity in the aliphatic part of the lead 1, is not cy

87 fluorine atom caused a small deviation from planarity in the chrysene series and decreased nonplanar

88 events these macrocycles from achieving full planarity in the ground state, and the ethynylene moieti

89 valine residues may allow the heme to regain planarity instead of being significantly ruffled, as in

90 idging adjacent rings for maintaining a high planarity, introduction of electron-withdrawing units fo

91 This global deviation from planarity is not observed for the Y257F variant.

92 dicates that the commonly stated chromophore planarity is not, but conformational rigidity is, the de

93 y as well as distortion of the rhomboid from planarity, leading to channels that can be observed from

94 The distortion of the pi-system from planarity leads to unusual packing in the solid state.

95 ibutes to small deviations from peptide bond planarity (<omega> = 179.3 +/- 3.1 degrees ) to the same

96 menon is not exclusive to cyclic systems-non-planarity may also be a critical biological design eleme

97 It has been suggested that changes in heme planarity may contribute to signal transduction.

98 lfgang Roth proposed that a system forced to planarity might have a smaller preference for the conrot

99 transition, and significant deviations from planarity occur only at higher temperatures, but well be

100 The backbone bond lengths, bond angles, and planarity of a protein are influenced by the backbone co

101 expected mechanistic subtleties, such as the planarity of an azatrimethylenemethane diyl intermediate

102 only by the synthetic difficulty and the non-planarity of annulenes with appropriate internal dimensi

103 e weaker bonding in the Nb-N network, the co-planarity of Nb-N layer as well as its relatively weaker

104 The planarity of peptide bonds is an assumption that underli

105 The effect of the improved planarity of pgBTTT manifested as higher hole mobility (

106 served as multiples has implications for the planarity of planetary systems.

107 hain of Trp-86 has the largest impact on the planarity of retinal, and the mutation of this amino aci

108 C-7 results in a significant deviation from planarity of the 5,7-diene moiety.

109 recombination to yield a cyclobutane by the planarity of the amide substituent.

110 Size and planarity of the aromatic side chain were crucially impo

111 Remarkably, the planarity of the benzene dianion originates from the sta

112 expectedly, we found that the deviation from planarity of the bidentate ligand, rather than the energ

113 c ring and the propeller-like deviation from planarity of the BPh phenanthrenyl ring.

114 1,2 dehydration of His66 as indicated by the planarity of the chromophore.

115 If the chlorine added does not distort the planarity of the conjugated core, we found that the chlo

116 oward a reduced allowed/forbidden gap as the planarity of the cyclobutene is enforced.

117 very significant distortion that breaks the planarity of the extended BODIPY pi system due to the st

118 conformation that significantly distorts the planarity of the extended conjugated system between the

119 zation, for the first time, we show that the planarity of the furan backbone is almost unaffected by

120 Near-planarity of the fused aminyl radicals and the 2,6,10-tr

121 as well as cis-indene carbonate display near planarity of the fused cyclopentene and benzene rings.

122 determined to a large part by the degree of planarity of the fused ring system whereas functional se

123 Furthermore, lack of planarity of the GpC cross-link precludes making an isos

124 The thickness and planarity of the graphenic shell increase with the CaC(2

125 tive site has negligible effects on both the planarity of the His-coordinated heme macrocycle and the

126 ric distortion is due to the requirement for planarity of the hydrogen bond connecting the two octade

127 perties of I and II are similar, whereas the planarity of the ligand in III greatly lowers the energy

128 The planarity of the ligand spacer favors a stereochemical c

129 their nonaromatic nature due to the lack of planarity of the macrocycle.

130 oup repels interfacial water to maintain the planarity of the molecule, indicating that lateral and t

131 ir identity and showed little deviation from planarity of the nucleobase.

132 he Bpin moiety is remarkably small, with the planarity of the oxygen-boron-oxygen motif playing an im

133 on annealing is attributed to an increase in planarity of the P3HT chains that is determined from the

134 ing pocket of the PDE10A enzyme to alter the planarity of the parent compound 1 and optimize its affi

135 The planarity of the polyene chain of the retinal chromophor

136 e have found evidence of correlation between planarity of the polymer chain and localization of the h

137 may be correlated to the enforcement of the planarity of the pyrone moiety leading to a quadrupolar

138 ere assigned to increased distortions of the planarity of the structure of the target molecule due to

139 iled that steric interactions disrupting the planarity of the system in the reduced state could be re

140 xyl counterparts presumably due to increased planarity of the system.

141 between their excited-state dynamics and the planarity of their flavin isoalloxazine ring.

142 The planarity of these species validates the discussion of t

143 The disruption of planarity of this ring and the similarities between FePL

144 GMR response on the separation between, and planarity of, the scanned sample stick and sensor.

145 , the dimensions and plane error (a gauge of planarity) of the fitted ellipse were calculated.

146 ostructure assembly and allowing the polymer planarity, optical absorption, and doping level to be mo

147 optimum for N2200 and PNBL-4,8-T2), backbone planarity (optimum for PNBA-2,6-T2 and PNBL-3,8-T2), LUM

148 at the macrocycles considerably diverge from planarity, particularly when methoxy substituents are pr

149 Distortions from planarity prevent charge delocalization as in the analog

150 excessive dendritic protrusion with loss of planarity, reduced resurgent sodium currents and abnorma

151 nar monomeric subunits or those with overall planarity, referred to as "Planar-Twisted-Planar" and "P

152 tic control in interlayer stacking and layer planarity renders an ordered network with a surface area

153 -hairpin structure of Tyrc A with additional planarity, resulting in approximately 30-fold reduced he

154 Decreased planarity results in a progressive blue-shift in the low

155 The structure lacks the planarity seen with the 5'-d(CpG) sequence and is skewed

156 fy favorable monomer properties such as core planarity, solubilizing substituent tailorability, and a

157 roducing two amine core units with different planarity, such as triazine and ionic guanidinium units,

158 up away from the benzene ring or the greater planarity that results from the additional cyclic struct

159 ring-opening transition structure approaches planarity, the energy gap between allowed conrotatory an

160 ent with no restraints on bond distances and planarity, the nicotinamide rings in the two complexes a

161 of the molecule shows strong deviation from planarity, the similar electrical resistance of the diff

162 ssile DNA backbone and emphasizes a need for planarity to afford potent biological activity.

163 oporphyrin IX group, which is distorted from planarity to an extent not seen before in protein-bound

164 d tropylium rings leads them to deviate from planarity to form contorted conformations in which aroma

165 control in this process, with maintenance of planarity to maximize a 1,5-S...O interaction within the

166 etries showed only slight shifts to the base planarity upon dearomatization by epoxidation, which is

167 the triazole ring where both N2-isomers lose planarity upon reduction.

168 and DIDBA-2H) with different degrees of non-planarity using three substituents (chloro, phenyl, and

169 n-benzenoid motifs enable the deviation from planarity, ususally presented in nanographenes, allowing

170 Distortions of the heme from planarity were characterized by normal coordinate struct

171 c acid are significantly distorted away from planarity, which apparently disrupts their internal hydr

172 sses longer effective conjugation and better planarity, which improves electron delocalization along

173 This tendency to deform from planarity, which is imparted by the ligand field strengt

174 e main structural feature of an amide is its planarity, which is responsible for the conjugation betw

175 length and a novel measure of basal turn non-planarity, which we suggest might correlate with the ris

176 lative, deviations from ideality in backbone planarity, which, if ignored, also lead to major errors

177 ineC-N-C(O) units deviate significantly from planarity with dihedral angles around the imide group re

178 maticity: energetic (stability), structural (planarity with equal bond lengths), and magnetic (negati

179 ements of the peripheral vinyl groups toward planarity with the heme macrocycle by cyt b 5 but away f

180 corrole ring showed a large distortion from planarity, with the Th(IV) and U(IV) ions residing unusu

181 pocket that permit the heme to relax toward planarity, yielding the signaling-competent NO-bound con