ライフサイエンスコーパス: plasma aldosterone

1 ce often occur in concert with elevations in plasma aldosterone.

2 (4) These mice show higher levels of the plasma aldosterone.

3 decreased renal Na(+) avidity and increased plasma aldosterone.

4 ore than 50% without changing PCa++, PK+, or plasma aldosterone.

5 phenotype, except for a 2.5-fold increase in plasma aldosterone.

6 re (94 +/- 2 vs. 89 +/- 2 mm Hg, P = 0.002), plasma aldosterone (149 +/- 18 vs. 109 +/- 10 pmol/L, P

7 - 9 mg/d) and thrombotic microangiopathy and plasma aldosterone (18 +/- 18 pg/ml) remained low but da

8 tassium (4.3+/-0.5 to 4.7+/-0.6 mmol/L), and plasma aldosterone (281 [198-431] to 351 [241-494] ng/L)

9 HiPro versus CON rats had higher plasma aldosterone (60.9 +/- 5.9 versus 42.2 +/- 4.4 pg/

10 c, inappropriate (dietary Na+) elevations in plasma aldosterone (ALDO) and a catabolic state that inc

11 NH4Cl treatment significantly decreased plasma aldosterone and antidiuretic hormone concentratio

12 Plasma aldosterone and ascorbic acid concentrations are

13 n, BKbeta1(-/-) strain A mice have increased plasma aldosterone and increased blood pressure.

14 of sodium in their feces and exhibited high plasma aldosterone and increased urinary sodium retentio

15 Despite life-long increase in plasma aldosterone and renin levels, no adverse cardiova

16 Low dietary Na+ intake raised rat plasma aldosterone and stimulated distal pericryptal she

17 Reduction in dietary Na+ intake raised plasma aldosterone and the capacity of the distal colon

18 The reduction of plasma renin activity, plasma aldosterone, and arginine vasopressin occurred ea

19 increase of plasma potassium (p < 0.02), but plasma aldosterone, angiotensin II (ANGII), and renin ac

20 ided clinical validation for the lowering of plasma aldosterone as a viable approach to modulate bloo

21 Plasma aldosterone, B-type natriuretic peptide, active r

22 ets, conditional KO mice displayed decreased plasma aldosterone but normal Na+/K+ balance.

23 Plasma aldosterone but not plasma renin activity was sig

24 Eplerenone and amiloride each increased plasma aldosterone by 3-fold and renin concentration sli

25 In contrast, inducing high levels of plasma aldosterone by a variety of methods completely co

26 adrenal glands and a > 10-fold elevation in plasma aldosterone compared to SHAM.

27 ations nearly 20-fold, which correlated with plasma aldosterone concentration and urinary Na/K ratio.

28 nd no difference in plasma renin activity or plasma aldosterone concentration between salt-fed wild-t

29 tensive patient, a serum potassium level and plasma aldosterone concentration to plasma renin activit

30 f hypertension, higher preoperative ratio of plasma aldosterone concentration to plasma renin activit

31 Plasma aldosterone concentration was also measured.

32 dditional measurement of serum potassium and plasma aldosterone concentration-plasma renin activity r

33 KNG1]: P=0.001 for plasma renin, P=0.024 for plasma aldosterone concentration; and rs4253311 with P<0

34 Renal renin activity, tissue Ang II and plasma aldosterone concentrations did not differ between

35 First, under conditions of increased plasma aldosterone concentrations, the heart will extrac

36 ng, tissue renin activity, tissue Ang II and plasma aldosterone concentrations.

37 eart failure produces sustained reduction in plasma aldosterone, consistent with the observed signifi

38 Plasma aldosterone fell from 68 +/- 59 ng/dL at baseline

39 ke (120 +/- 124 versus 580 +/- 442 pg/ml for plasma aldosterone, group 1 versus group 2, P = 0.03, an

40 n activity [PRA] <=1.0 ng/mL/h) and elevated plasma aldosterone (>=1.0 ng/dL) were enrolled, with sub

41 High plasma aldosterone has deleterious cardiovascular effect

42 ensate for impaired ENaC activation, rise in plasma aldosterone in response to low-salt diet was enha

43 In contrast, loss of BKbeta1 did not affect plasma aldosterone in strain C mice.

44 Plasma aldosterone increased briefly after high-dose PDE

45 Plasma aldosterone increased with Fs (41+/-10 to 100+/-1

46 Plasma aldosterone is increased in NHE3-deficient mice,

47 Increases in systolic blood pressure, plasma aldosterone level, and urinary and heart prostano

48 Plasma aldosterone levels (P(aldo)) were comparable duri

49 Eleven of the 34 subjects had plasma aldosterone levels above the upper limit of norma

50 We simultaneously measured plasma aldosterone levels and the degree of inhibition o

51 Furthermore, elevated plasma aldosterone levels are associated with increased

52 Plasma aldosterone levels are elevated in patients with

53 Plasma aldosterone levels are elevated in patients with

54 nd baxdrostat at several dose levels reduced plasma aldosterone levels but not cortisol levels.

55 Plasma aldosterone levels by radioimmunoassay demonstrat

56 The very high plasma aldosterone levels detected under hypovolemic or

57 ffects of an angiotensin receptor blocker on plasma aldosterone levels in patients with NYHA class II

58 Adrenalectomy + ALDO showed plasma aldosterone levels of 735 +/- 147 pg/ml; plasma p

59 In control mice, rosiglitazone did not alter plasma aldosterone levels or protein expression of ENaC

60 ical studies have demonstrated that elevated plasma aldosterone levels predict the development of ins

61 duced-potassium diet (rescue diet), although plasma aldosterone levels remained significantly increas

62 asurements of adrenal CYP11B2 expression and plasma aldosterone levels showed that increases in endog

63 was increased, and plasma renin activity and plasma aldosterone levels were decreased after the HS di

64 enin concentrations were modestly higher and plasma aldosterone levels were lower in Sglt2(-/-) mice.

65 At 2 wk, plasma renin activity and plasma aldosterone levels were lower in the POL group.

66 However, plasma aldosterone levels were significantly suppressed

67 Plasma aldosterone levels were unchanged.

68 ing the intron conversion have (a) increased plasma aldosterone levels, (b) increased hCYP11B2 mRNA a

69 Systolic BP (SBP), 24-h protein excretion, plasma aldosterone levels, 24-h urinary aldosterone excr

70 In Study 3, the relationship between plasma aldosterone levels, alcohol drinking and craving

71 1, we investigated the relationship between plasma aldosterone levels, ethanol self-administration a

72 hs accompanied with proportionate changes in plasma aldosterone levels, whereas plasma volumes ranged

73 enin-angiotensin pathway leading to elevated plasma aldosterone levels.

74 phosphorylation of NCC protein, despite high plasma aldosterone levels.

75 hibited sodium loss through feces and higher plasma aldosterone levels.

76 on, increased GFR, and significantly reduced plasma aldosterone levels.

77 ese mice lost the normal circadian rhythm of plasma aldosterone levels.

78 d FE(Na) than wild-type mice despite similar plasma aldosterone levels.

79 ted thrombotic microangiopathy and decreased plasma aldosterone (<16 versus 710 +/- 91 pg/ml; P < 0.0

80 oncentration (P=0.01) and a trend for higher plasma aldosterone (P=0.06), but measures of home BP, pl

81 Plasma renin activity, plasma aldosterone, plasma and 24 h urine sodium and pot

82 Patients' work-up included plasma aldosterone, plasma renin activity, serum cortiso

83 negatively and significantly correlated with plasma aldosterone (r=-0.38, P=0.0006), 24-hour urinary

84 In conjunction with the lower plasma aldosterone, rats in the POL group had higher pla

85 ommon nonpressor effects included changes in plasma aldosterone, renal function, cardiac variables, a

86 Rates of primary aldosteronism testing (plasma aldosterone-renin) and the association of testing

87 otassium intake, Tmprss2(-/-) mice increased plasma aldosterone significantly more than wild-type mic

88 ldosterone (r=-0.49, P<0.0001), and ratio of plasma aldosterone to plasma renin activity (r=-0.43, P<

89 ely evaluated with an early-morning ratio of plasma aldosterone to plasma renin activity and 24-hour

90 chemical and clinical success (reductions in plasma aldosterone to renin ratio and blood pressure 6 m

91 A plasma aldosterone to renin ratio is a useful screening

92 adenomas in patients with elevated ratios of plasma aldosterone to renin.

93 were observed in plasma renin concentration, plasma aldosterone, urine vasopressin, or urine PGE(2) b

94 Plasma aldosterone was elevated approximately 5- and 15-

95 Plasma aldosterone was increased in slc26a3-null mice.

96 Plasma aldosterone was measured by radioimmunoassay in c

97 haracteristic of primary aldosteronism), but plasma aldosterone was only elevated in male animals.

98 After 4 weeks of therapy, plasma aldosterone was reduced by valsartan 80 mg BID (-

99 Renal plasma flow and plasma aldosterone were measured before and after a 45-m

100 Of note, smaller increases in plasma aldosterone were required to adapt renal Na+ excr

101 in signaling elevated CYP11B2 expression and plasma aldosterone, whereas deficiency in leptin or lept