ライフサイエンスコーパス: plasticity

1 ynaptic transmission that influence synaptic plasticity.

2 trafficking, which is essential for synaptic plasticity.

3 t infection profiles through transcriptional plasticity.

4 abling adaptive convergence independently of plasticity.

5 ere impact, indicating beneficial phenotypic plasticity.

6 isk environments due to genetic variation in plasticity.

7 y located receptors that can impair synaptic plasticity.

8 nderstand the evolution of multi-dimensional plasticity.

9 work properties and contribute to behavioral plasticity.

10 nravel the mechanisms underlying place field plasticity.

11 ns of synaptic morphology, transmission, and plasticity.

12 nd dendritic spine shrinkage during synaptic plasticity.

13 profoundly negative consequences on synaptic plasticity.

14 expand on the notion of underlying aberrant plasticity.

15 iet periods of training undergoes structural plasticity.

16 immunity, synapse development, and synaptic plasticity.

17 rgets for regulation during various forms of plasticity.

18 s to msp300 transcripts and is essential for plasticity.

19 usly been implicated in hippocampal synaptic plasticity.

20 pment, excitatory synaptic transmission, and plasticity.

21 tions in genes that are critical to synaptic plasticity.

22 tput control, motivational drive, and neural plasticity.

23 of more powerful directed types of synaptic plasticity.

24 otrophins have critical roles in adult brain plasticity.

25 with depression-like behaviors and synaptic plasticity.

26 ns using chemogenetics similarly enhanced V1 plasticity.

27 o neuropathology by causing dysregulation of plasticity.

28 cuit changes underlying experience-dependent plasticity.

29 of cellular status on initiation of lineage plasticity.

30 ressed feeding tests, and increased synaptic plasticity.

31 mately controlling synaptic transmission and plasticity.

32 e on thermal reaction norms, reflecting such plasticity.

33 mice of either sex on cognition and synaptic plasticity.

34 the stability of ECoG interfaces and neural plasticity.

35 various MAPs in activity-dependent synaptic plasticity.

36 t seems to induce this adaptive life-history plasticity.

37 ulates both spectral sensitivity and sensory plasticity.

38 n types, modulating dynamics and influencing plasticity.

39 d they are rarely associated with behavioral plasticity.

40 iological signatures of maladaptive neuronal plasticity; a phenomenon associated with LID.

41 in these neurons, which affects bursting and plasticity, abolishes lever pressing for postingestive s

42 et, the neural mechanisms underlying circuit plasticity across cue-food learning, cue memory recall,

43 GNIFICANCE STATEMENT The decline of cortical plasticity after closure of juvenile critical period con

44 al period" (CP), during which high levels of plasticity allow neural circuits to be tuned for optimal

45 Developmental plasticity allows genomes to encode multiple distinct ph

46 nvironmental signals controlling cancer cell plasticity along EMT and suggests that hybrid and mesenc

47 indings highlight both conserved aspects and plasticity among arrestin-receptor interactions.

48 Variation in phenotypic plasticity among invader populations suggests the potent

49 haracterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but

50 he role of neurotrophins in modulating brain plasticity and apoptosis.

51 ing gap junctions undergo activity-dependent plasticity and complex regulation.

52 : The importance of timing and timescales in plasticity and critical periods of brain development; ep

53 es NMDARs and AMPARs, as well as its role in plasticity and disease.

54 le of the endocannabinoid system in synaptic plasticity and emotional memory processing.

55 mate change, however, may include individual plasticity and evolution of populations.

56 h tactile rehabilitation to enhance synaptic plasticity and facilitate recovery of sensory function.

57 ings substantiate the role of social-network plasticity and feedback as key adaptive mechanisms for r

58 inhibition, indicative of enhanced dendritic plasticity and filtering of signals integrated at the so

59 e potential for transgenerational phenotypic plasticity and genetic adaption, the keys to resistance.

60 Both plasticity and genetic differentiation can contribute to

61 ts a dynamic interplay between developmental plasticity and immune-mediated pruning during metastasis

62 ocal microenvironments that impact stem cell plasticity and impair regenerative capacity.

63 ay is triggered by the induction of synaptic plasticity and in response to object location learning.

64 own about stress-induced inhibitory synaptic plasticity and its relevance for neuropsychiatric diseas

65 , SK2, contributes to impairment of synaptic plasticity and learning in AS mice.

66 ctivity-dependent genes, as well as synaptic plasticity and memory formation.

67 of proteins essential for long-term synaptic plasticity and memory.

68 ymmetry, we investigated changes in synaptic plasticity and neuronal excitability of BLA neurons in v

69 Here we reveal extensive phenotypic plasticity and niche complementarity in oleaginous micro

70 gnaling exhibits a high degree of functional plasticity and redundancy through myriad mutational path

71 Maintaining the right balance between plasticity and robustness in biological systems is impor

72 e concomitant maintenance of transcriptional plasticity and stem cell robustness.

73 ges did not impair synaptic transmission and plasticity and synaptic vesicle release kinetics.

74 actions respond differently to physiological plasticity and to distinct motor learning tasks, which s

75 bled genomes were used to understand genomic plasticity and to perform coalescent analyses.

76 ave directly assessed ancestral variation in plasticity and tracked phenotypic changes over time.

77 sable vesicles reliably reproduce short-term plasticity and variance of synaptic responses.

78 tudy this variation (lineage, phenotype, and plasticity) and its relevance to human biology remain un

79 eek, can enable hippocampal memory, synaptic plasticity, and alter hippocampal excitability when occu

80 taos on glutamatergic transmission, synaptic plasticity, and dendritic spine structure.

81 ions suggests the potential for evolution of plasticity, and greater plasticity of invader population

82 PP family in neuronal excitability, synaptic plasticity, and memory in adulthood, despite the lack of

83 nded role of autophagy in neuronal function, plasticity, and memory.

84 n associated with cancer cell heterogeneity, plasticity, and metastasis.

85 MARCKS supports development, synaptic plasticity, and regeneration after injury.

86 itin chains in neural development, function, plasticity, and related pathologies.

87 relationship between glutamate dynamics and plasticity, and the mechanisms linking these two phenome

88 es in nonneoplastic cells requires metabolic plasticity, and this plasticity is increasingly recogniz

89 nisms underlying hunger-dependent behavioral plasticity are not fully characterized.

90 ic regulation of ion transport and metabolic plasticity are required to maintain osmotic and protein

91 The molecular mechanisms governing such plasticity are undefined.

92 uits exhibited abnormal experience-dependent plasticity as they did not adapt to chronically presente

93 ynamic functional connection with short-term plasticity as well as effects due to the recent history

94 for enhancing experience-dependent cortical plasticity as well as functional recovery in adulthood.S

95 ading to defective synaptic transmission and plasticity as well as impaired executive functions.

96 itional food can induce similar life-history plasticity, as does experimental food supplementation.

97 apable of discovering adaptive forms of cell plasticity associated with complex logical functions.

98 tudies demonstrate increased transcriptional plasticity associated with generalist compared with spec

99 y development of somatotopy, patterning, and plasticity at both the morphologic and physiological lev

100 triggered intrinsic and synaptic homeostatic plasticity at different timescales in hippocampal excita

101 trength is malleable, induction of long-term plasticity at distinct inhibitory synapses and its regul

102 MKII controls the bidirectional inversion of plasticity at parallel fibre (PF)-Purkinje cell (PC) syn

103 synaptic transmission and long-term synaptic plasticity at the Cornu Ammonis (CA) 3-CA1 synapses.

104 hibition (E/I) balance and aberrant synaptic plasticity at the cortical level.

105 s, BATF requires the STAT5 signal to mediate plasticity at the Il9 locus.

106 the fracture strain by providing structural plasticity at the network and fiber level.

107 that glutamatergic signaling contributes to plasticity at the NMJ.

108 Our findings reveal the neural plasticity-based mechanism for ketamine-mediated functio

109 Motor learning depends on synaptic plasticity between corticostriatal projections and stria

110 more than one resistance mechanism, and the plasticity between multiple resistance mechanisms could

111 inhibitory innervation and ocular dominance plasticity between NF1 mice and WT littermates disappear

112 cally organized maps, neural patterning, and plasticity, both in development and in maturity.

113 ommonalities between homeostatic and Hebbian plasticity but also connect homeostatic regulation of sy

114 bited normal cognitive function and synaptic plasticity but had increased dendritic spine density com

115 ved in neuronal differentiation and synaptic plasticity but the molecular mechanisms behind these pro

116 PNNs restrict cortical network plasticity but the molecular mechanisms involved are unc

117 prisingly invoked mechanisms akin to Hebbian plasticity: Ca(2+)-permeable AMPA receptor upregulation,

118 How plasticity can contribute or hinder adaptation to differ

119 mediated through a common transitional, high-plasticity cell state (HPCS).

120 of observations, while reproducing cellular plasticity commonly observed during development.

121 Some models of phenotypic plasticity conceptualise the response as a relatively si

122 Mechanisms of cellular and circuit-level plasticity continue to shape and reshape many regions of

123 red maintenance of synaptic transmission and plasticity, contributing to autism-associated behavioral

124 This plasticity-coupling link predicts that neurons with high

125 d synaptic scaling and intrinsic homeostatic plasticity, deficits that could be rescued by treatment

126 The design principles for engineering plasticity described can be applied to numerous material

127 and pathological processes, such as neuronal plasticity, development, and viral invasion.

128 tanding of the dynamics and functions of EMT plasticity during cancer metastasis.

129 to determine the mechanisms of mitochondrial plasticity during chronic exposure to cold and hypoxia,

130 Endothelial cells (ECs) display remarkable plasticity during development before becoming quiescent

131 monstrate a potential role of extrapyramidal plasticity during functional recovery after SCI.

132 d receptor membrane trafficking and synaptic plasticity during memory reconsolidation.

133 ers establishing epithelial-mesenchymal cell plasticity during reversible and irreversible EMT.

134 The development and consequences of lineage plasticity during tumorigenesis have remained mysterious

135 e review current understanding of NE lineage plasticity dynamics, exemplified by prostate cancer, NSC

136 ry processing in cortical networks and gates plasticity enabling adaptive behavior.

137 history dependent and error based, providing plasticity essential for flexible decision-making.

138 me that eosinophils are capable of metabolic plasticity, evidenced by increased glucose-derived lacta

139 k a rigorous, mechanistic examination of how plasticity evolves in a large comparative framework.

140 Plasticity extends to visual features beyond ocular domi

141 The plasticity-first hypothesis [2-4] proposes that natural

142 ce a locally adaptive trait, but the role of plasticity for adaptive evolution is still unclear [5-10

143 t activity, excitatory feedback, or synaptic plasticity for storage.

144 wired as well as compensatory reticulospinal plasticity for the recovery of locomotor functions follo

145 oform-specific functions of GSK3 in synaptic plasticity has not been fully explored.

146 tical modulator of blood pressure and neural plasticity; however, the mechanism by which TNFalpha sig

147 The role of phenotypic plasticity in adaptive evolution has been debated for de

148 will help unravel the role of mitochondrial plasticity in aging and disease.

149 ensive genetic variation in predator-induced plasticity in ancestral populations of Daphnia It is unl

150 ay for understanding transient cell fate and plasticity in biological processes.

151 A well-known pathway of lineage plasticity in cancer - the histological transformation o

152 g molecular mechanisms controlling metabolic plasticity in cancer.

153 tex express BDNF as a potential regulator of plasticity in corticostriatal projections in male and fe

154 l signaling protein that suppresses synaptic plasticity in dendritic spines of hippocampal neurons.

155 tion of synaptic transmission and short-term plasticity in endbulb synapses.

156 more, effects of junk-foods on glutamatergic plasticity in females are unknown.

157 nguish laminar specificity of visual circuit plasticity in humans.

158 tween stability and flexibility and enabling plasticity in information processing.

159 ike the critical period for ocular dominance plasticity in mammals, be extended by blocking sensory n

160 Even though plasticity in many traits is genetically controlled, whe

161 tion of acini involves induction of cellular plasticity in multiple non-acinar cell populations.

162 To investigate the role of mesenchymal plasticity in PDAC progression, we generated a PDAC mous

163 aled that the PIs better adapt to structural plasticity in PR with resistance-associated amino acid s

164 cilitates learning in human participants via plasticity in prefrontal white matter tracts and a coloc

165 redictable environment likely is enhanced by plasticity in production of the different types of diasp

166 We show that this plasticity in rats is robust at 1 and at 3 months but re

167 Phenotypic plasticity in relation to temperature can allow organism

168 studies have only investigated life-history plasticity in response to changes in temperature, yet wi

169 The limitation of plasticity in the adult brain impedes functional recover

170 gnaling modulator, enhances ocular dominance plasticity in the adult primary visual cortex (V1).

171 eptors (NMDARs) plays a key role in synaptic plasticity in the central nervous system (CNS).

172 rmed on warm-acclimated fish to test whether plasticity in the form of inducible warm tolerance also

173 e discovery of impaired hippocampal synaptic plasticity in the heterozygous mouse model sheds light o

174 display motor deficits and impaired synaptic plasticity in the striatum.

175 The genetic basis of variation and plasticity in these traits was investigated via genome-w

176 hat 3 mo of OLT1177 diet can rescue synaptic plasticity in this mouse model of AD (P = 0.007 to untre

177 ng vmPFC input to examine punishment-related plasticity in this pathway.

178 atural and sexual selection shape phenotypic plasticity in two congeneric and phenotypically similar

179 ght changes caused by spike timing dependent plasticity increase the distance between the odor repres

180 eep or by REM sleep, whether it results from plasticity increases or stabilization, and whether facil

181 that L4 restricts disinhibition and gates OD plasticity independent of a canonical cortical microcirc

182 opping we found evidence for both individual plasticity (individuals decrease their migration distanc

183 ow that the CP for behavioral and structural plasticity induced by ethyl butyrate (EB) or carbon diox

184 ccumbens, opioid-induced excitatory synaptic plasticity involves presynaptic and postsynaptic element

185 ormones and suggests that hormonal signaling plasticity is a general cross-kingdom strategy to fend o

186 Epigenetic plasticity is a pivotal factor that drives metastasis.

187 Lack of dynamic plasticity is a significant limitation for artificial sy

188 Although plasticity is a valuable trait that allows the human bra

189 This neurotransmitter plasticity is activity-dependent, as was revealed by che

190 hesized that the cell type-specific synaptic plasticity is associated with parallel cell-specific act

191 nstrate that a window of heightened vascular plasticity is coupled to the reestablishment of blood fl

192 Myelin plasticity is critical for neurological function, includ

193 These findings suggest that VWFA plasticity is harnessed to compensate for STGp dysfuncti

194 Accounting for this behavioural plasticity is important, both in terms of measuring effe

195 ells requires metabolic plasticity, and this plasticity is increasingly recognized to play a central

196 Homeostatic plasticity is likely to play a role in diseases associat

197 suggesting that the current level of thermal plasticity is maladaptive in the context of anthropogeni

198 xperimental evidence indicates that synaptic plasticity is metabolically demanding as well.

199 we generated a PDAC mouse model in which CAF plasticity is modulated by genetic depletion of the tran

200 Plasticity is often regarded as a derived adaptation to

201 Such fully reversible plasticity is predominantly governed by the conservative

202 nt, the critical period for ocular dominance plasticity is shortened in NF1 mice due to its early clo

203 with bond strength, indicating that ensemble plasticity is specific to partner approach.

204 thway, because it has been proposed that the plasticity is uniformly expressed across all synapses.

205 e the growing interest in activity-dependent plasticity, it is still unclear whether synaptic plastic

206 This period of enhanced plasticity leads to the sprouting of new axons, the form

207 However, hippocampal synaptic plasticity, learning, and memory are impaired in these m

208 f genotype provenance and whether phenotypic plasticity maintains performance in a changing environme

209 come, and that larger amounts of hippocampal plasticity may not be conducive to positive antidepressa

210 ocus implicated in synaptic transmission and plasticity may serve as a possible biological mediator o

211 anges in tissues can be driven by stochastic plasticity, meaning rare stochastic transitions of singl

212 iverse cellular mechanisms underlying varied plasticity modes.

213 Since the discovery of ocular dominance plasticity, neuroscientists have understood that changes

214 se neurons, which could regulate maladaptive plasticity observed in chronic pain.

215 Where in the brain and how such plasticity occurs remains largely unknown.

216 ery is accompanied by pronounced spontaneous plasticity of axotomized and spared reticulospinal axons

217 is hybrid phenotype can facilitate metabolic plasticity of cancer cells more specifically in metastas

218 In light of the metabolic heterogeneity and plasticity of cancer cells that had until recently remai

219 red expression profiles, revealing extensive plasticity of cell types and cell-type-specific gene exp

220 blood and lymphatic vessels by limiting the plasticity of committed endothelial cells.

221 Herein, we describe an adaptive signaling plasticity of CRLF2-rearranged Ph-like ALL following sel

222 environments, not only does sensing promote plasticity of dispersal morph ratio, individuals who can

223 This unprecedented structural plasticity of helical repeats may be a general regulator

224 lization of different T cell subsets and the plasticity of individual naive T cells to adopt differen

225 ial for evolution of plasticity, and greater plasticity of invader populations than native species ma

226 s brief review examines the training-induced plasticity of key elements in the O(2) transport pathway

227 ccumbens (NAc), structural and physiological plasticity of medium spiny neurons (MSNs) have been link

228 cuss the origin, distribution, function, and plasticity of renin cells within the kidney and immune c

229 etween mouse and human lesions and extensive plasticity of SMC- and endothelial cell-derived cells in

230 hered our understanding of the diversity and plasticity of SSCs that mediate skeletal maintenance and

231 In an attempt to increase the plasticity of the "stage hierarchy" approach as well as

232 many possible contributors for the inherent plasticity of the adult brain.

233 s demonstrate that CBFbeta can determine the plasticity of the metastatic cancer cell phenotype, sugg

234 fications are detected, indicating a certain plasticity of the pathway in the amoeba.

235 g modes is largely encoded in the structural plasticity of the receptors themselves and of their sign

236 enegalensis), the current study confirms the plasticity of the retina in response to the natural phot

237 In particular, the plasticity of these cells or their dynamic ability to tr

238 ical stimulation revealed normal homeostatic plasticity of Up-states, however, Fmr1(-/y) circuits exh

239 a single individual, revealing a structural plasticity of VH1-69-derived bNAbs.

240 t inputs on cortical excitability and neural plasticity often used transcranial magnetic stimulation

241 provide an overview of the impact of lineage plasticity on cancer progression and therapy resistance,

242 Intergenerational plasticity or parental effects-when parental environment

243 complex makeup that also shows developmental plasticity, particularly for 22-nt sRNAs.

244 asome improves behavioral tests and synaptic plasticity phenotypes in a murine model of the disease.

245 yl-4-isoxazolepropionic acid (AMPA) receptor plasticity plays a role in sustaining seizures, seizure

246 er, it remains unclear what role hippocampal plasticity plays in the antidepressant response to ECT.

247 atopallidal transmission, while compensatory plasticity prevents STN hyperactivity and limits cortica

248 and where polygenic evolution of phenotypic plasticity proceeded from standing variation and de novo

249 noradrenergic neuromodulation of hippocampal plasticity processes.

250 evelopmental acquisition of the synapse- and plasticity properties of PV-INs, we investigated conditi

251 piking neurons that emulate transmission and plasticity properties of real synapses.

252 Our findings imply that low connectivity and plasticity provide protective mechanisms against network

253 or tinnitus may need to enhance the cortical plasticity, rather than reverse it.

254 FR-mutant lung cancer, as SOX2-mediated cell plasticity regulated by TGFbeta stimulation and epigenet

255 is known about the role of interneurons and plasticity-related molecules on such mechanisms.

256 MDARs, and in wild-type mice this structural plasticity required activation of mTORC1 and new protein

257 Protein levels of p27 were associated with plasticity/rigidity of the cell cycle and correlated wit

258 We demonstrate that the plasticity rules depend highly on three factors: (1) the

259 ticity, it is still unclear whether synaptic plasticity rules inferred from in vitro experiments are

260 tory population change according to distinct plasticity rules.

261 connectivity motifs that may follow specific plasticity rules.

262 s is genetically controlled, whether and how plasticity's genetic architecture might change in novel

263 It is unlikely that the standing patterns of plasticity shielded Daphnia from selection to permit lon

264 ging patients and athletes to promote neural plasticity, skilled performance, and recovery.

265 corporated the signature short-term synaptic plasticity (STP) profiles of the inhibitory parvalbumin

266 silently' maintained via short-term synaptic plasticity (STSP) without the need for persistent activi

267 systems, ecological factors that can induce plasticity (such as food and density) covary.

268 Because of its involvement in synaptic plasticity, SynGAP has emerged as a critical protein for

269 Transgenerational plasticity (TGP) occurs when the environment encountered

270 upon our understanding of transgenerational plasticity (TGP), which occurs when environments experie

271 r results provide direct evidence for neural plasticity that compensates for the deficiency in the in

272 reby establishing a state of transcriptional plasticity that enables the emergence of antiandrogen re

273 y transmission (iLTD), a form of presynaptic plasticity that involves a protein-synthesis-dependent l

274 Macrophages demonstrate remarkable plasticity that is essential for host defense and tissue

275 essential regulator of ILC3 homeostasis and plasticity that limits physiological ILC1 conversion.

276 reveal a hidden form of inhibitory synaptic plasticity that prevents accumulation of excitatory LTP.

277 elicits a unique form of functional synaptic plasticity that shares several attributes and molecular

278 t aspect in intratumor heterogeneity is cell plasticity-the ability of a cell to switch to new identi

279 nstrations of their importance in regulating plasticity, their precise functional mechanisms remain e

280 ala contribute to such a teaching signal for plasticity, thereby facilitating the formation of fear m

281 hich is likely necessary to maintain network plasticity to accommodate growth and morphogenesis.

282 ine roots of trees exhibit varying degree of plasticity to adapt to environmental stress.

283 hat could harness adolescent neurobehavioral plasticity to improve resilience and recovery for some o

284 s, including S100a10 (p11), linking neuronal plasticity to the antidepressant response.

285 Understanding phenotypic plasticity under natural conditions is hindered by the a

286 Neutrophil diversity and plasticity underlie the dual potential of TANs in the tu

287 s a basic morphogenetic process of high cell plasticity underlying embryogenesis, wound healing, canc

288 ngs suggest that hypoxia-induced respiratory plasticity was characterized by spatially confined mitoc

289 nder projections of climate change, predator plasticity was insufficient to keep pace with prey pheno

290 igns of local adaptation, overall phenotypic plasticity was not sufficient for phenological events to

291 The inclusion of plasticity, which allows shifts in competitive hierarchi

292 n around 10-20% of these patients is lineage plasticity, which manifests in a partial or complete sma

293 SWI/SNF complexes in therapy-related lineage plasticity, which may also be relevant for other solid t

294 upply alone rescued stress-impaired synaptic plasticity, which was blocked by inhibiting neural lacta

295 d subpopulations of MDSCs exhibit remarkable plasticity, with homogeneous/sorted subpopulations givin

296 We also quantified phenotype and plasticity within and among sites and determined the ext

297 Plasticity within hippocampal circuits is essential for

298 lts suggest that the location of ECT-related plasticity within the hippocampus may differ according t

299 come of activity-dependent forms of synaptic plasticity, yet activity-independent processes might als

300 uli are among the main drivers of behavioral plasticity, yet, how animals evolve and modulate functio